يعرض 1 - 10 نتائج من 59 نتيجة بحث عن '"Clark III, Donald"', وقت الاستعلام: 1.17s تنقيح النتائج
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    دورية أكاديمية
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    المصدر: Blood Pressure Monitoring ; volume 29, issue 1, page 23-30 ; ISSN 1359-5237

    الوصف: Background Mean systolic and diastolic blood pressure (SBP and DBP) on ambulatory blood pressure (BP) monitoring (ABPM) are higher among Black compared with White adults. With 48 to 72 BP measurements obtained over 24 h, ABPM can generate parameters other than mean BP that are associated with increased risk for cardiovascular events. There are few data on race differences in ABPM parameters other than mean BP. Methods To estimate differences between White and Black participants in ABPM parameters, we used pooled data from five US-based studies in which participants completed ABPM (n = 2580). We calculated measures of SBP and DBP level, including mean, load, peak, and measures of SBP and DBP variability, including average real variability (ARV) and peak increase. Results There were 1513 (58.6%) Black and 1067 (41.4%) White participants with mean ages of 56.1 and 49.0 years, respectively. After multivariable adjustment, asleep SBP and DBP load were 5.7% (95% CI: 3.5–7.9%) and 2.7% (95% CI: 1.1–4.3%) higher, respectively, among Black compared with White participants. Black compared with White participants also had higher awake DBP ARV (0.3 [95%CI: 0.0–0.6] mmHg) and peak increase in DBP (0.4 [95% CI: 0.0–0.8] mmHg). There was no evidence of Black:White differences in awake measures of SBP level, asleep peak SBP or DBP, awake and asleep measures of SBP variability or asleep measures of DBP variability after multivariable adjustment. Conclusion Asleep SBP load, awake DBP ARV and peak increase in awake DBP were higher in Black compared to White participants, independent of mean BP on ABPM.

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    المصدر: Journal of Cardiac Failure; Feb2023, Vol. 29 Issue 2, p150-157, 8p

    مستخلص: • A lower serum vitamin D 3 concentration has been associated with an increased risk of cardiovascular disease. However, the associations between serum vitamin D 3 levels and heart failure with preserved ejection fraction (HFpEF) have not been well-characterized. • Lower serum vitamin D 3 levels were associated with left ventricular concentric remodeling and incident HF, mainly HFpEF in Black Americans. • Further investigation is required to examine whether supplementation of vitamin D 3 can prevent left ventricular concentric remodeling and incident HFpEF in Black Americans. In observational studies, a lower serum vitamin D 3 concentration has been associated with an increased risk of cardiovascular disease. However, the associations between serum vitamin D 3 levels and left ventricular (LV) structure and heart failure with preserved ejection fraction (HFpEF) have not been well-characterized among Black Americans. The prevalence of vitamin D 3 deficiency is higher among Black Americans than in other race/ethnicity groups. We hypothesized that serum vitamin D 3 levels are associated with LV concentric remodeling and incident HFpEF in Black Americans. Among 5306 Black Americans in the Jackson Heart Study cohort, we investigated the relationships between serum vitamin D 3 levels and LV structure and function, evaluated with echocardiography, and incident HF hospitalization, categorized as either HF with reduced EF (HFrEF; an EF of <50%) or HFpEF (an EF of ≥50%). After adjustment for possible confounding factors, lower vitamin D 3 levels were associated with greater relative wall thickness (β for 1 standard deviation [SD] increase –0.003, 95% confidence interval –0.005 to –0.000). Over a median follow-up period of 11 years (range 10.2–11.0 years), 340 participants developed incident HF (7.88 cases per 1000 person-years), including 146 (43%) HFrEF and 194 (57%) HFpEF cases. After adjustment, higher serum vitamin D 3 levels were associated with decreased hazard for HF overall (hazard ratio for 1 SD increase 0.88, 95% confidence interval 0.78–0.99) driven by a significant association with HFpEF (hazard ratio for 1 SD increase 0.84, 95% confidence interval 0.71–0.99). In this community-based Black American cohort, lower serum vitamin D 3 levels were associated with LV concentric remodeling and an increased hazard for HF, mainly HFpEF. Further investigation is required to examine whether supplementation with vitamin D 3 can prevent LV concentric remodeling and incident HFpEF in Black Americans. [Display omitted] [ABSTRACT FROM AUTHOR]

    : Copyright of Journal of Cardiac Failure is the property of W B Saunders and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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    المصدر: Hypertension (0194911X); Oct2022, Vol. 79 Issue 10, p2199-2201, 3p

    مستخلص: Two recent pivotal studies offer an opportunity to shift the thinking on population strategies to reduce dietary sodium intake to improve cardiovascular health. Sorting out the potential contribution of increasing potassium intake in these studies has been a matter of interest for decades.[3] Increasing potassium intake without lowering sodium intake has a modest effect on lowering blood pressure. [Extracted from the article]

    : Copyright of Hypertension (0194911X) is the property of Lippincott Williams & Wilkins and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)