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المؤلفون: Robert Touitou, Géraldine Bart, Marion Couderc, E. Veillard, Pascal Guggenbuhl, P. Coquerelle, Sophie Godot, Christian Lormeau, Denis Mulleman, Guillaume Coiffier, Carine Salliot, Marion Baldeyrou, Beate Hyem, Jean-Marc Ziza, Thomas W. Bauer, René-Marc Flipo, Christelle Darrieutort-Laffite, Raphaèle Seror, Bernard Fouquet, Louis Bernard
المساهمون: Imagerie Moléculaire et Stratégies Théranostiques (IMoST), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Clermont Auvergne (UCA), CHU Gabriel Montpied [Clermont-Ferrand], CHU Clermont-Ferrand
المصدر: Joint Bone Spine
Joint Bone Spine, 2020, 87 (6), pp.538-547. ⟨10.1016/j.jbspin.2020.07.012⟩
Joint Bone Spine, Elsevier Masson, 2020, 87 (6), pp.538-547. ⟨10.1016/j.jbspin.2020.07.012⟩مصطلحات موضوعية: Adult, Staphylococcus aureus, medicine.medical_specialty, medicine.drug_class, [SDV]Life Sciences [q-bio], Antibiotics, 03 medical and health sciences, 0302 clinical medicine, Rheumatology, Internal medicine, Humans, Medicine, Streptococcus gallolyticus, 030212 general & internal medicine, Medical diagnosis, Intensive care medicine, ComputingMilieux_MISCELLANEOUS, Language, 030203 arthritis & rheumatology, Arthritis, Infectious, business.industry, Staphylococcal Infections, medicine.disease, Anti-Bacterial Agents, 3. Good health, Joint aspiration, Infective endocarditis, Septic arthritis, business, Trauma surgery
الوصف: Septic arthritis (SA) in an adult native joint is a rare condition but a diagnostic emergency due to the morbidity and mortality and the functional risk related to structural damage. Current management varies and the recommendations available are dated. The French Rheumatology Society (SFR) Bone and Joint Infection Working Group, together with the French Language Infectious Diseases Society (SPILF) and the French Orthopaedic and Trauma Surgery Society (SOFCOT) have worked according to the HAS methodology to devise clinical practice recommendations to diagnose and treat SA in an adult native joint. One new focus is on the importance of microbiological documentation (blood cultures and joint aspiration) before starting antibiotic treatment, looking for differential diagnoses (microcrystal detection), the relevance of a joint ultrasound to guide aspiration, and the indication to perform a reference X-ray. A cardiac ultrasound is indicated only in cases of SA involving Staphylococcus aureus, oral streptococci, Streptococcus gallolyticus or Enterococcus faecalis, or when infective endocarditis is clinically suspected. Regarding treatment, we stress the importance of medical and surgical collaboration. Antibiotic therapies (drugs and durations) are presented in the form of didactic tables according to the main bacteria in question (staphylococci, streptococci and gram-negative rods). Probabilistic antibiotic therapy should only be used for patients with serious symptoms. Lastly, non-drug treatments such as joint drainage and early physical therapy are the subject of specific recommendations.
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9308e225fae67b0cbfb68fa506305f5Test
https://doi.org/10.1016/j.jbspin.2020.07.012Test -
22
المؤلفون: Claire Bernier, Hélène Aubert, Jean-Marie Berthelot, Antoine Néel, Christian Agard, Sébastien Barbarot, Benoit Le Goff, Mohamed Hamidou, Agathe Masseau, Françoise Kraeber-Bodéré, Christelle Darrieutort-Laffite, Catherine Ansquer
المصدر: Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-10 (2020)
Arthritis Research & Therapyمصطلحات موضوعية: Male, medicine.medical_specialty, lcsh:Diseases of the musculoskeletal system, Interleukin 1 receptor antagonist, Single Center, Cohort Studies, 030207 dermatology & venereal diseases, 03 medical and health sciences, 0302 clinical medicine, Schnitzler syndrome, Musculoskeletal Pain, Internal medicine, medicine, Humans, Bone pain, Retrospective Studies, business.industry, Waldenstrom macroglobulinemia, Retrospective cohort study, Bone scan, medicine.disease, Rash, Rheumatology, Bone lesions, Cohort, Female, medicine.symptom, lcsh:RC925-935, business, 030215 immunology, Research Article, Follow-Up Studies
الوصف: Objective To report on the characteristics and long-term course of rheumatic manifestations in Schnitzler syndrome (SchS). Methods A retrospective cohort study of patients with SchS followed between 2000 and 2020. Inclusion criteria included a diagnosis of SchS (Strasbourg criteria). All available bone scans were reviewed and scored according to the intensity and number of pathological sites. The scintigraphic score was compared with the clinical activity score, CRP level, and treatments. Results Twenty-five patients were included. Median age at diagnosis was 68 years. Eighty patients (72%) had SchS-related rheumatic pain. Most patients had a long-standing isolated rash before constitutional and/or rheumatic symptoms appeared. The monoclonal component level was usually very low (IgMκ in 22/25). Rheumatic pain predominated around the knees. Bone scans revealed abnormal tracer uptake in 15/18 (85%). The scintigraphic score correlated with clinical activity (r = 0.4, p r = 0.47, p p Conclusions Rheumatic manifestations are very prevalent in SchS. However, bone pain can be misleading and contribute to misdiagnosis. Bone scan abnormalities are very prevalent and correlate with disease activity and treatments. IL1-Ra has a dramatic and durable efficacy but may not be required in every patient early on.
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52bd4540be4dcd843b01445f9f1276c5Test
http://link.springer.com/article/10.1186/s13075-020-02318-5Test -
23
المؤلفون: Benoit Le Goff, Christelle Darrieutort-Laffite
المساهمون: Service de rhumatologie, Centre Hospitalier Universitaire de Nice (CHU Nice)-Hôpital l'Archet
المصدر: Revue du Rhumatisme monographies
Revue du Rhumatisme monographies, Elsevier, 2020, 87, pp.217-221. ⟨10.1016/j.monrhu.2020.02.004⟩مصطلحات موضوعية: 030203 arthritis & rheumatology, 03 medical and health sciences, 0302 clinical medicine, Rheumatology, [SDV]Life Sciences [q-bio], 030218 nuclear medicine & medical imaging
الوصف: Resume Les tendinopathies calcifiantes de la coiffe sont une des causes les plus frequentes de douleurs chroniques de l’epaule, impactant generalement la vie quotidienne et professionnelle des patients. Apres l’echec du traitement de premiere intention associant antalgiques/AINS, kinesitherapie et infiltration de corticoides, un geste d’exerese de la calcification sous echographie est generalement propose. Cette revue reprend les differentes techniques utilisees : lavage a une ou deux aiguilles ou fragmentation seule, en detaillant leur mise en œuvre, leur efficacite et leurs complications. Les trois techniques ont une efficacite semblant equivalente bien que peu d’etudes comparatives soient disponibles. Les complications rapportees sont peu severes, essentiellement des malaises vagaux au cours du geste et une recrudescence des douleurs dans les 3 a 4 mois suivant le geste. De rares cas de bursites septiques ont ete rapportes (4 en tout). Enfin, bien que la technique soit quasi exclusivement etudiee au niveau de l’epaule, d’autres localisations (hanche, genou, coude) ont egalement ete traitees avec succes.
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f827019fc20f8ce590f937c42940124Test
https://doi.org/10.1016/j.monrhu.2020.02.004Test -
24
المؤلفون: Stéphane Ploteau, Benoit Le Goff, Jean-Marie Berthelot, Christelle Darrieutort-Laffite, Frédéric Douane
المصدر: Joint bone spine. 89(2)
مصطلحات موضوعية: business.industry, Spinal stenosis, Hyperemia, Anatomy, medicine.disease, Thrombosis, Venous stasis, medicine.anatomical_structure, Rheumatology, Pregnancy, Tissue Plasminogen Activator, Vasa nervorum, medicine, Humans, Female, Arachnoiditis, Radiculopathies, business, Varices, Vein, Radiculopathy, Spinal Nerve Roots, Intervertebral Disc Displacement
الوصف: Compression of roots/nerves can disrupt some of their functions, but does not necessarily cause pain. This is illustrated by the frequency of nearly asymptomatic spinal stenosis or disc herniations. In fact, pain of radiculopathies (and nerve entrapments) may mostly be the consequence of intraneural oedema induced by microscopical venous stasis around roots/spinal ganglia (or nerves) not or poorly shown by imaging. This narrative review first lists arguments for a role of congestion of vasa-nervorum in the pathophysiology of radiculopathies, including those induced by disc herniation and spinal stenosis, but also other sources of overpressures in spinal venous plexuses (pregnancy, vena cava atresia and thrombosis, portal hypertension, epidural varices, arterio-venous fistula, vertebral hemangioma or hemangioblastoma). It also details sources of venous congestion around nerves outside the spine, from pelvis (May-Thurner syndrome, Nut-cracker syndrome) to buttocks (superior and inferior gluteal veins), and even thighs and legs. A better recognition of a preeminent role of venous congestion in radiculopathies, plexopathies, and nerve entrapments, should have major consequences: (i) discard the dogma that compression is mandatory to induce root/nerve suffering, since root/nerve adherences in two locations can impair blood flow in vasa-nervorum through root/nerve stretching; (ii) implementation of sensitive techniques to visualise impingement of blood flow around or within roots and nerves; (iii) better prevention of roots/nerves adherence, or arachnoiditis induced by extravascular fibrin deposition secondary to venous stasis.; (iv) optimizing treatments dampening clot formation and/or extravascular fibrin leakage in the intradural/peridural spaces, or around roots/nerves, like guided injection of tissue plasminogen activator.
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::882023f8cc3172e7a7bb0c801c413ab5Test
https://pubmed.ncbi.nlm.nih.gov/34653602Test -
25
المصدر: Frontiers in Medicine
Frontiers in Medicine, Vol 8 (2021)مصطلحات موضوعية: medicine.medical_specialty, Medicine (General), diagnosis, Context (language use), Stimulus (physiology), psyche, 03 medical and health sciences, 0302 clinical medicine, Physical medicine and rehabilitation, R5-920, hypersensitisation, Fibromyalgia, medicine, Chronic fatigue syndrome, pain, Restless legs syndrome, 030203 arthritis & rheumatology, business.industry, Cognitive disorder, Chronic pain, Chronic fatigue, General Medicine, medicine.disease, neuro-imaging, Perspective, Medicine, fibromyalgia, fatigue, business, 030217 neurology & neurosurgery
الوصف: The concept of fibromyalgia has progressed to achieve a certain consensus regarding the definition of the condition. We summarize what is known in 2020, be it in terms of diagnosis, with the criteria that have changed over the years, or at the level of the psychological profile, via the notions of “catastrophizing” and “coping” and post-traumatic syndrome. The importance of fatigue and sleep disorders is underlined, with the chronological sequence of post-traumatic syndrome, chronic fatigue, and then amplification of the pain and the onset of multiple associated symptoms. The etiopathogenic debate has been enriched thanks to neuro-imaging data to discover the start of the central neurological signature. The many associated symptoms are reanalyzed in the context of so-called sister conditions which form sometimes more or less separate entities, such as chronic fatigue syndrome or restless legs syndrome for example. What these conditions have in common is hypersensitivity, not just to pain, but also to all exteroceptive stimuli, from deep sensitivity in the neuro-vegetative system, the sense organs and certain functions of the central nervous system, to the psychological aspects and sleep control. In summary, it is possible to define fibromyalgia as a cognitive disorder of cortical integration of chronic pain, with amplification of painful and sensory nociception, decrease in the threshold for the perception of pain, and persistence of a stimulus that maintains the process in chronicity. Fibromyalgia is part of a group of chronic hypersensitivity syndromes of central origin, with a very wide range of means of expression.
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04cf44b17490b63a226cb30e3f2278eeTest
http://europepmc.org/articles/PMC8316633Test -
26
المؤلفون: Caroline Trang, Jean-Marie Berthelot, Yves Maugars, Christelle Darrieutort-Laffite, Benoit Le Goff
المصدر: Joint bone spine. 88(6)
مصطلحات موضوعية: Mycobiota, Innate immune system, biology, business.industry, Microbiota, Fungi, Chromosomal translocation, biology.organism_classification, medicine.disease, Fungal antigen, Microbiology, Gastrointestinal Microbiome, Pathogenesis, CARD Signaling Adaptor Proteins, Mice, Rheumatology, Antigen, Spondylarthritis, Medicine, Animals, Dysbiosis, Humans, business, Bacteria
الوصف: This review lists current evidences for a contribution of gut mycobiota to the pathogenesis of SpA and related conditions. Gut mycobiota has a small size as compared to bacterial microbiota, but an even greater inter- and intra-individual variability. Although most fungi (brought by food or air) are only transitory present, a core mycobiota of gut resident fungi exists, and interplays with bacteria in a complex manner. A dysbiosis of this gut mycobiota has been observed in Crohn's disease and sclerosing cholangitis, with decreased proportion of Saccharomyces cerevisiae and outgrowth of more pathogenic gut fungi. Fungal-induced lower number of commensal gut bacteria can promote translocation of some bacterial/fungal antigens through mucosae, and live fungi can also cross the epithelial border in Crohn's disease. This dysbiosis also lower the ability of bacteria to metabolize tryptophan into regulatory metabolites, consequently enhancing tryptophan metabolism within human cells, which might contribute to fatigue. Translocation of mycobiotal antigens like curdlan (beta-glucan), which plays a major role in the pathogenesis of SpA in the SGK mice, has been observed in humans. This translocation of fungal antigens in human SpA might account for the anti-Saccharomyces antibodies found in this setting. Contribution of fungal antigens to psoriasis and hidradenitis suppurativa would fit with the preferential homing of fungi in the skin area most involved in those conditions. Fungal antigens also possess autoimmune uveitis-promoting function. As genes associated with SpA (CARD9 and IL23R) strongly regulate the innate immune response against fungi, further studies on fungi contribution to SpA are needed.
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb9c2609c7db856b5156dfbf9e51520cTest
https://pubmed.ncbi.nlm.nih.gov/34166798Test -
27
المؤلفون: Benoit Le Goff, Jean-David Albert, Nicolas Dumoulin, Guillaume Coiffier, Grégoire Cormier, Stéphane Varin, Christelle Darrieutort-Laffite
المصدر: The American journal of sports medicine. 49(4)
مصطلحات موضوعية: medicine.medical_specialty, Percutaneous, Physical Therapy, Sports Therapy and Rehabilitation, law.invention, 03 medical and health sciences, Rotator Cuff, 0302 clinical medicine, Randomized controlled trial, law, Shoulder Pain, Post-hoc analysis, medicine, Effective treatment, Humans, Orthopedics and Sports Medicine, Rotator cuff, Calcific tendinopathy, Therapeutic Irrigation, Ultrasonography, Interventional, 030203 arthritis & rheumatology, 030222 orthopedics, business.industry, Calcific tendinitis, medicine.disease, Ultrasound guided, Surgery, medicine.anatomical_structure, Treatment Outcome, Case-Control Studies, Tendinopathy, business
الوصف: Background: Calcific tendinitis of the rotator cuff is a frequent cause of shoulder pain. Ultrasound-guided percutaneous lavage (UGPL) is an effective treatment, but factors associated with good clinical and radiological outcomes still need to be identified. Purpose: To study the clinical, procedural, and radiological characteristics associated with improved shoulder function and the disappearance of calcification on radiograph after UGPL. Study Design: Case-control study; Level of evidence, 3. Methods: This is a post hoc analysis of the CALCECHO trial, a double-blinded randomized controlled trial conducted on 132 patients. The trial assessed the effect of corticosteroid injections after UGPL, and patients were randomly assigned to receive either corticosteroid or saline solution in the subacromial bursa. We analyzed all patients included in the randomized controlled trial as 1 cohort. We collected the patients’ clinical, procedural, and radiological characteristics at baseline and during follow-up (3, 6, and 12 months). Univariable analysis, followed by multivariable stepwise regression through forward elimination, was performed to identify the factors associated with clinical success (Disabilities of the Arm, Shoulder and Hand [DASH] score Results: Good clinical outcomes at 3 months were associated with steroid injections after the procedure (odd ratio [OR], 3.143; 95% CI, 1.105-8.94). At 6 months, good clinical evolution was associated with a lower DASH score at 3 months (OR, 0.92; 95% CI, 0.890-0.956) and calcium extraction (OR, 10.7; 95% CI, 1.791-63.927). A lower DASH at 6 months was also associated with a long-term favorable outcome at 12 months (OR, 0.939; 95% CI, 0.912-0.966). Disappearance of calcification at 3 and 12 months occurred more frequently in patients in whom communication was created between the calcification and the subacromial bursa during the procedure (OR, 2.728 [95% CI, 1.194-6.234] at 3 months; OR, 9.835 [95% CI, 1.977-48.931] at 12 months). Importantly, an association between calcification resorption and good clinical outcome was found at each time point. Conclusion: Assessing patients at 3 months seems to be an essential part of their management strategy. Calcium extraction and creating a communication between the calcific deposits and subacromial bursa are procedural characteristics associated with good clinical and radiological evolution.
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e855bca0fe1586773a1e4c6ad4a64346Test
https://pubmed.ncbi.nlm.nih.gov/33719606Test -
28
المؤلفون: Christelle Darrieutort-Laffite, Pascale Guillot, Jean-Marie Berthelot, Benoit Le Goff, Joëlle Glémarec, Yves Maugars
المصدر: Revue du Rhumatisme. 87:89-91
مصطلحات موضوعية: Rheumatology, business.industry, Medicine, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::2e47021b51d5a6830443f5ad41458d35Test
https://doi.org/10.1016/j.rhum.2019.07.017Test -
29دورية أكاديمية
المؤلفون: Nicolas Dumoulin (802389), Grégoire Cormier (9439115), Stéphane Varin (10310245), Guillaume Coiffier (10310248), Jean-David Albert (10310251), Benoit Le Goff (10310254), Christelle Darrieutort-Laffite (10310257)
مصطلحات موضوعية: Orthopaedics, Surgery, Sports Medicine, rotator cuff, calcific tendinitis, treatment, prognostic factor
الوصف: Supplemental material, sj-pdf-1-ajs-10.1177_0363546521992359 for Factors Associated With Clinical Improvement and the Disappearance of Calcifications After Ultrasound-Guided Percutaneous Lavage of Rotator Cuff Calcific Tendinopathy: A Post Hoc Analysis of a Randomized Controlled Trial by Nicolas Dumoulin, Grégoire Cormier, Stéphane Varin, Guillaume Coiffier, Jean-David Albert, Benoit Le Goff and Christelle Darrieutort-Laffite in The American Journal of Sports Medicine
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المؤلفون: Stéphane Varin, Grégoire Cormier, Lucie Planche, Benoit Le Goff, Guillaume Coiffier, Jean-David Albert, Christelle Darrieutort-Laffite, Yves Maugars
المصدر: Annals of the Rheumatic Diseases. 78:837-843
مصطلحات موضوعية: Adult, Male, Visual analogue scale, medicine.medical_treatment, Immunology, Equivalence Trials as Topic, Punctures, Methylprednisolone, General Biochemistry, Genetics and Molecular Biology, Injections, Intra-Articular, Rotator Cuff, 03 medical and health sciences, 0302 clinical medicine, Double-Blind Method, Rheumatology, Tendinitis, Shoulder Pain, Humans, Immunology and Allergy, Medicine, Therapeutic Irrigation, Glucocorticoids, Saline, Ultrasonography, Interventional, Pain Measurement, 030203 arthritis & rheumatology, Pain, Postoperative, 030222 orthopedics, Dry needling, business.industry, Calcinosis, Calcific tendinitis, Middle Aged, medicine.disease, Acute Pain, Treatment Outcome, Anesthesia, Tendinopathy, Female, Saline Solution, Subacromial bursa, business, Follow-Up Studies, medicine.drug, Calcification
الوصف: ObjectiveSteroid injections are common after an ultrasound-guided puncture and lavage (UGPL) of calcific tendonitis of the rotator cuff. However, steroids may prevent calcification resorption and negatively affect tendon healing. Our study was designed to determine whether saline solution was non-inferior to steroids in the prevention of acute pain reactions in the week following UGPL.MethodsThis was a randomised, double-blinded, controlled non-inferiority trial with 12-month follow-up. We included 132 patients (66 in each group) with symptomatic calcification measuring more than 5 mm. Patients received 1 mL of saline or steroid (methylprednisolone 40 mg) in the subacromial bursa at the end of UGPL. Primary outcome was the maximal pain during the week following the procedure with a prespecified non-inferiority margin of 10 mm (0–100 visual analogue scale). Secondary outcomes included pain at rest and during activity, function (disabilities of the arm, shoulder and hand score) and radiological evolution of the calcification over the 12-month follow-up.ResultsThe estimated mean difference in the first week’s maximal pain between these two groups was 11.76 (95% CI 3.78 to 19.75). Steroids significantly improved VAS pain at rest and during activities, as well as function at 7 days and 6 weeks. They did not change the rate of calcification resorption, which occurred in 83% and 74% of patients at 12 months in the saline and steroid groups.ConclusionNon-inferiority of saline when compared with steroids could not be established. However, steroid injection improved pain in the 6 weeks following the procedure, and function in the 3 months after, with no significant effect on calcification resorption.Trial registration numberNTC02403856.
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcece3babe2a404951bc62970e939b9fTest
https://doi.org/10.1136/annrheumdis-2018-214971Test
