المؤلفون: Cheng, Hao-Wei, 程皓瑋

مرشدي الرسالة: Zhuang, Shao-Xun, 莊紹勳

الوصف: 105
In the coming Internet-of-Things (IOT) era, the market have huge demand for embedded memory. In the past, One-Time-Programing memory are the most promising one because of low cost, easy-integrated on chip and excellent data retention. But the OTP can be only programmed once, which has the risk of miss-coding. However, although Multi-Time-Programming memory can program and erase lots of times, data retention is a serious problem. For the above characteristics, we design a novel rewritable OTP, RW-OTP, which combines both the multi-time programming capability and excellent data retention. First, we will introduce the bilayer RRAM, which is an important element as a storage cell by utilizing the switching characteristic between low resistance state (LRS) and high resistance state (HRS). In order to explore the physical mechanism of RRAM, we designed an experiment to locate the soft-breakdown path by the RTN measurement technique, from which we can extract the trap position and energy level by collecting the capture and emission time. We then locate the generation of traps as a function of time and complete the conductive path for three different conditions, i.e., the paths during forming, set, and reset. Results showed that, in the set path, filament links top-electrode and bottom-electrode and forms a low resistance state (LRS). In the reset path, filament is broken near the top-electrode and became a low resistance state (HRS). Moreover, the interesting characteristics of dielectric-fuse breakdown are also examined. Next, according to the above understandings on the filament formation, we design a new type of OTP which can modify the data at first and store the data permanently when users confirm it is of no problem. The fuse characteristics have excellent retention ability for security requirement. At the circuit level, the one selector and one RRAM (1S1R) array has been designed to resist the sneak current. Other experiments shows that this new type of RW-OTP has the ability of large window, disturb immunity, excellent data retention, and great endurance.

وصف الملف: 76

الإتاحة: http://ndltd.ncl.edu.tw/handle/50476237590221207841Test

المؤلفون: Cheng, Hao‐Wei, Chein, Rong‐Jie, Cheng, Ting‐Jen, Wu, Pei‐Shan, Wu, Hsin‐Yi, Hung, Pei‐Fang, Wang, Chia‐Jen, Hsu, Yuan‐Ling, Wong, Jau‐Min, Yuan, Ang, Wong, Chi‐Huey, Yang, Pan‐Chyr, Pan, Szu‐Hua

المساهمون: National Taiwan University, Academia Sinica, Ministry of Science and Technology

المصدر: Cancer Science ; volume 109, issue 3, page 832-842 ; ISSN 1347-9032 1349-7006

الوصف: Lung cancer is the leading cause of cancer‐related death worldwide. Thus, developing novel therapeutic agents has become critical for lung cancer treatment. In this study, compound AS7128 was selected from a 2‐million entry chemical library screening and identified as a candidate drug against non‐small cell lung cancer in vitro and in vivo. Further investigation indicated that AS7128 could induce cell apoptosis and cell cycle arrest, especially in the mitosis stage. In addition, we also found that iASPP, an oncogenic protein that functionally inhibits p53, might be associated with AS7128 through mass identification. Further exploration indicated that AS7128 treatment could restore the transactivation ability of p53 and, thus, increase the expressions of its downstream target genes, which are related to cell cycle arrest and apoptosis. This occurs through disruption of the interactions between p53 and iASPP in cells. Taken together, AS7128 could bind to iASPP, disrupt the interaction between iASPP and p53, and result in cell cycle arrest and apoptosis. These findings may provide new insight for using iASPP as a therapeutic target for non‐small cell lung cancer treatment.

الإتاحة: https://doi.org/10.1111/cas.13489Test

المؤلفون: Cheng, Hao-Wei, Chen, Yi-Fang, Wong, Jau-Min, Weng, Chia-Wei, Chen, Hsuan-Yu, Yu, Sung-Liang, Chen, Huei-Wen, Yuan, Ang, Chen, Jeremy J.W.

المساهمون: Ministry of Science and Technology, Taiwan

المصدر: Journal of Experimental & Clinical Cancer Research ; volume 36, issue 1 ; ISSN 1756-9966

مصطلحات موضوعية: Cancer Research, Oncology

الإتاحة: https://doi.org/10.1186/s13046-017-0495-3Test

المؤلفون: Hwang, Wen-Li, Chen, Tsung-Chih, Lin, Hsuan-Yu, Chang, Ming-Chih, Hsiao, Pei-Ching, Bai, Li-Yuan, Kuo, Ching-Yuan, Chen, Yeu-Chin, Liu, Ta-Chih, Gau, Jyh-Pyng, Wang, Po-Nan, Hwang, Wei-Shou, Kuo, Ming-Chung, Liu, Chun-Yu, Liu, Yi-Chang, Ma, Ming-Chun, Su, Nai-Wen, Wang, Chuan-Cheng, Wu, Yi-Ying, Yao, Ming, Yeh, Su-Peng, Cheng, Hao-Wei, Lee, Yee-Ming, Ku, Fan-Chen, Tang, Jih-Luh

المساهمون: Novartis Pharma AG, Basel

المصدر: International Journal of Hematology ; volume 115, issue 5, page 704-712 ; ISSN 0925-5710 1865-3774

مصطلحات موضوعية: Hematology

الإتاحة: https://doi.org/10.1007/s12185-022-03311-1Test

المؤلفون: Huakun Que, Mark Junjie Li, Cheng Hao Wei, Ji Kui Wang, Guoying Lin, Shi Xiang Lu

المصدر: International Journal of Machine Learning and Cybernetics. 10:1313-1322

مصطلحات موضوعية: business.industry, 020209 energy, 020208 electrical & electronic engineering, Computational intelligence, Feature selection, Pattern recognition, 02 engineering and technology, Grey relational analysis, Fault detection and isolation, Support vector machine, Artificial Intelligence, Kriging, Ground-penetrating radar, Pattern recognition (psychology), 0202 electrical engineering, electronic engineering, information engineering, Computer Vision and Pattern Recognition, Artificial intelligence, business, Software, Mathematics

الوصف: The prediction of the dissolved gases content in an oil-immersed power transformer is very important for early fault detection. However, it is quite difficult to obtain accurate predictions due to the non-linearity of gas data. Different machine learning technics have been used to solve this problem, but they neither consider the relationship of different gases nor the sampling errors. In this paper, we propose to use Grey relational analysis (GRA) to calculate grey relational coefficients for gas feature selection and a Gaussian process regression (GPR) to predict dissolved gas value. In this method, both the relationship of gas features and sampling errors are considered. Four algorithms of ANN, SVM, LSSVM and GPR are used in gas prediction. We conducted experiments on eight dissolved gas datasets. The comparison results have shown that the GRA method is effective in selecting good gas features. The performance of prediction of gas values is significantly improved.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::48bc9af7d739a4d58b4fac078fa5dd01Test
https://doi.org/10.1007/s13042-018-0812-yTest

المؤلفون: Yuan, Ang, Lin, Chien-Yuan, Chou, Cheng-Hung, Shih, Chia-Ming, Chen, Chih-Yuan, Cheng, Hao-Wei, Chen, Yi-Fang, Chen, Jeremy J. W., Chen, Jyh-Horng, Yang, Pan-Chyr, Chang, Chen

المساهمون: Bernhard, Eric J.

المصدر: PLoS ONE ; volume 6, issue 1, page e16062 ; ISSN 1932-6203

الإتاحة: https://doi.org/10.1371/journal.pone.0016062Test

المؤلفون: Ho, Bing-Ching, Yu, Sung-Liang, Chen, Jeremy J.W., Chang, Sui-Yuan, Yan, Bo-Shiun, Hong, Qi-Sheng, Singh, Sher, Kao, Chuan-Liang, Chen, Hsuan-Yu, Su, Kang-Yi, Li, Ker-Chau, Cheng, Chiou-Ling, Cheng, Hao-Wei, Lee, Jen-Yi, Lee, Chun-Nan, Yang, Pan-Chyr

المصدر: Cell Host & Microbe ; volume 9, issue 1, page 58-69 ; ISSN 1931-3128

مصطلحات موضوعية: Virology, Microbiology, Parasitology

الإتاحة: https://doi.org/10.1016/j.chom.2010.12.001Test
https://api.elsevier.com/content/article/PII:S1931312810004117?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S1931312810004117?httpAccept=text/plainTest

مستخلص: Files of various file formats are converted into markup language files, such as HTML files or XML-based files, and a compound web document is generated from the markup language files so that the compound web document may be displayed using a web browser, such as Internet Explorer. Files of the above-mentioned file formats may include a PowerPoint file (*.ppt), a Word file (*.doc), an Excel file (*.xls), a single packaged web page (*.mht), and an image file (*.bmp, *.jpg, *.gif, *.png). Thus the compound web document may be retrieved without linking any other files.

المؤلفون: Ma, Shang-Chih, Cheng, Hao-Wei, Tan, Tan-Hsu

المصدر: 2018 7th International Symposium on Next Generation Electronics (ISNE)

الإتاحة: https://doi.org/10.1109/isne.2018.8394699Test
http://xplorestaging.ieee.org/ielx7/8385418/8393497/08394699.pdf?arnumber=8394699Test

مستخلص: A system and method of automatically transforming instant message transmission modes on the Internet is disclosed. The transformation system is applied to a Java-based instant messenger and could be automatically transformed to four transmission modes in accordance with different network environments. The four transmission modes include the socket mode (i.e. direct connection through socket), HTTP 1.1 mode (i.e. connection through a proxy server and a firewall that both support HTTP 1.1), HTTP 1.0 mode (i.e. connection through a proxy server and a firewall that both support HTTP 1.0) and a pure-HTML mode (i.e. without JAVA applet).