المؤلفون: Dario Melilli, Vinícius Felipe Wandscher, Leonardo Ciocca, Giuseppe Currò, Candida Parisi, Giuseppe Gallina, Paolo Baldissara

المصدر: Brazilian Journal of Oral Sciences, Vol 19 (2020)

مصطلحات موضوعية: Air abrasion, dental, Cementation, Denture retention, Surface properties, Dentistry, RK1-715

الوصف: Aim: To evaluate the retention of an endodontic titanium postwith a spherical head for removable partial denture or overdentureattachment according to surface treatment type. Methods: Sixtyhealthy single-rooted teeth, sectioned at the enamel/cementumjunction, were treated endodontically and steadily fixed in theembedding acrylic resin. The titanium posts were subdivided intofour groups: control, no surface treatment (Ctrl); posts with macroretentivegrooves (MR); air abrasion of the post surface (AB); andposts with macro-retentive grooves and air abrasion of the postsurface (MR+AB). The posts were luted in the root canal usingself-adhesive dual resin cement. Pull-out testing was performedusing a universal testing machine until complete detachment wasachieved. After pull-out testing, the metallic posts were examinedunder an optical microscope and the failures were classifiedbased on the cement distribution pattern on the extracted posts:0, no cement left on the post (cement/post failure); 1, postsurface partially covered by adhered cement (post/cement anddentin/cement mixed failure); 2, post surface completely coveredby cement (dentin/cement failure). The retention data wereanalyzed by one-way ANOVA, Bonferroni–Dunn test (p

وصف الملف: electronic resource

العلاقة: https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8658798Test; https://doaj.org/toc/1677-3225Test

الوصول الحر: https://doaj.org/article/ccfd3626086741dd8f8e4b3989ed496cTest

المؤلفون: Marilia Trindade, Jessica Castro de Vasconcelos, Gabriel Ayub, Alex Treiger Grupenmacher, Delma Regina Gomes Huarachi, Marina Viturino, Maria Lucia Correa-Giannella, Yeelen Ballesteros Atala, Denise Engelbrecht Zantut-Wittmann, Maria Candida Parisi, Monica Alves

المصدر: Frontiers in Endocrinology, Vol 12 (2021)

مصطلحات موضوعية: ocular surface, diabetes, Charcot arthropathy, neuropathy, dry eye, cardiovascular autonomic neuropathy, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

الوصف: ObjectiveDiabetes can affect the eye in many ways beyond retinopathy. This study sought to evaluate ocular disease and determine any associations with peripheral neuropathy (PN) or cardiac autonomic neuropathy (CAN) in type 2 diabetes (T2D) and Charcot arthropathy (CA) patients.DesignA total of 60 participants were included, 16 of whom were individuals with T2D/CA, 21 of whom were individuals with T2D who did not have CA, and 23 of whom were healthy controls. Ocular surface evaluations were performed, and cases of dry eye disease (DED) were determined using the Ocular Surface Disease Index (OSDI) questionnaire, ocular surface staining, Schirmer test, and Oculus Keratograph 5M exams. All variables were used to classify DED and ocular surface disorders such as aqueous deficiency, lipid deficiency, inflammation, and ocular surface damage. Pupillary and retinal nerve fiber measurements were added to the protocol in order to broaden the scope of the neurosensory ocular evaluation. PN and CAN were ascertained by clinical examinations involving the Neuropathy Disability Score (for PN) and Ewing’s battery (for CAN).ResultsMost ocular variables evaluated herein differed significantly between T2D patients and controls. When the controls were respectively compared to patients with T2D and to patients with both T2D and CA, they differed substantially in terms of visual acuity (0.92 ± 0.11, 0.73 ± 0.27, and 0.47 ± 0.26, p=0.001), retinal nerve fiber layer thickness (96.83 ± 6.91, 89.25 ± 10.44, and 80.37 ± 11.67 µm, p=0.03), pupillometry results (4.10 ± 0.61, 3.48 ± 0.88, and 2.75 ± 0.81 mm, p=0.0001), and dry eye symptoms (9.19 ± 11.71, 19.83 ± 19.08, and 24.82 ± 24.40, p=0.03). DED and ocular surface damage also differed between individuals with and without CA, and were associated with PN and CAN.ConclusionCA was found to be significantly associated with the severity of ocular findings. DED in cases of CA was also associated with PN and CAN. These findings suggest that intrinsic and complex neurosensory impairment in the ...

العلاقة: https://www.frontiersin.org/articles/10.3389/fendo.2021.585823/fullTest; https://doaj.org/toc/1664-2392Test; https://doaj.org/article/6d3e611c24554f1e8532f4286424d695Test

الإتاحة: https://doi.org/10.3389/fendo.2021.585823Test
https://doaj.org/article/6d3e611c24554f1e8532f4286424d695Test

المؤلفون: Mozania Reis de Matos, Daniele Pereira Santos-Bezerra, Cristiane das Graças Dias Cavalcante, Jacira Xavier de Carvalho, Juliana Leite, Jose Antonio Januario Neves, Sharon Nina Admoni, Marisa Passarelli, Maria Candida Parisi, Maria Lucia Correa-Giannella

المصدر: International Journal of Environmental Research and Public Health; Volume 17; Issue 9; Pages: 3232

مصطلحات موضوعية: diabetic neuropathy, distal symmetric polyneuropathy, primary care, cardiovascular autonomic neuropathy

جغرافية الموضوع: agris

الوصف: The paucity of epidemiological data regarding diabetes complications in Brazil motivated us to evaluate the prevalence rates of distal symmetric polyneuropathy (DSP) and of cardiovascular autonomic neuropathy (CAN) in individuals with type 2 diabetes (T2D) followed in a primary care unit. A total of 551 individuals (59.3% women, 65 years old; diabetes duration of 10 years; HbA1c of 7.2%, medians) were included in this cross-sectional study. DSP was diagnosed by sum of the Neuropathy Symptoms Score (NSS) and Modified Neuropathy Disability Score (NDS) and by the Semmes–Weinstein monofilament. CAN was diagnosed by cardiovascular autonomic reflex tests combined with spectral analysis of heart rate variability. The prevalence rates of DSP were 6.3% and 14.3%, as evaluated by the sum of NSS and NDS and by the Semmes–Weinstein monofilament, respectively. Those with DSP diagnosed by monofilament presented longer diabetes duration, worse glycemic control and a higher stature. The prevalence rates of incipient and definitive CAN were 12.5% and 10%, respectively. Individuals with definitive CAN presented a higher frequency of hypercholesterolemia and of arterial hypertension. The higher prevalence rate of DSP with the use of the monofilament suggests that it may be a more appropriate tool to diagnose DSP in the primary care setting in Brazil.

وصف الملف: application/pdf

العلاقة: Health Behavior, Chronic Disease and Health Promotion; https://dx.doi.org/10.3390/ijerph17093232Test

الإتاحة: https://doi.org/10.3390/ijerph17093232Test

المؤلفون: Daniele Pereira Santos‐Bezerra, Sharon Nina Admoni, Rosana Cristina Mori, Tatiana Souza Pelaes, Ricardo Vesoni Perez, Cleide Guimarães Machado, Maria Beatriz Monteiro, Maria Candida Parisi, Elizabeth Joao Pavin, Marcia Silva Queiroz, Marisa Passarelli, Ubiratan Fabres Machado, Maria Lucia Correa‐Giannella

المصدر: Journal of Diabetes Investigation, Vol 10, Iss 4, Pp 985-989 (2019)

مصطلحات موضوعية: Chronic complications, Epigenetics, Metabolic memory, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

الوصف: Aims/Introduction Epigenetics participate in the pathogenesis of metabolic memory, a situation in which hyperglycemia exerts prolonged deleterious effects even after its normalization. We tested the hypothesis that genetic variants in an epigenetic gene could predispose to diabetes complications. Material and Methods We assessed the frequency of five single‐nucleotide polymorphisms in the gene encoding deoxyribonucleic acid methytransferase 1 (DNMT1; rs8112895, rs7254567, rs11085721, rs17291414 and rs10854076), and their associations with diabetic kidney disease, retinopathy, distal polyneuropathy and autonomic cardiovascular neuropathy in 359 individuals with long‐term type 1 diabetes. Results None of the single‐nucleotide polymorphisms studied was significantly associated with the presence of chronic complications in the overall population. However, after sex stratification, the minor allele C of rs11085721 conferred risk for cardiovascular neuropathy in women after adjustment for confounding variables (odds ratio 2.32; 95% confidence interval 1.26–4.33; P = 0.006). Conclusions The fact that heterozygous mutations in DNMT1 are associated with hereditary sensory autonomic neuropathy provides plausibility to the present finding. If confirmed in independent samples, it suggests that genetic variants in epigenetic genes might predispose to more or fewer epigenetic changes in the face of similar metabolic derangements triggered by hyperglycemia, constituting the “genetics of epigenetics” for microvascular diabetes complications.

العلاقة: https://doi.org/10.1111/jdi.12988Test; https://doaj.org/toc/2040-1116Test; https://doaj.org/toc/2040-1124Test; https://doaj.org/article/a12e2c6a042d43d98e39dfcebac8cc10Test

الإتاحة: https://doi.org/10.1111/jdi.12988Test
https://doaj.org/article/a12e2c6a042d43d98e39dfcebac8cc10Test

المؤلفون: Leonilda Maria Barbosa dos Santos, Silvia B. Marques, Candida Parisi, Elizabeth João Pavin, Sofia Helena Valente de Lemos Marini, Fernando Pradella, Emílio Carlos Elias Baracat, Alessandro dos Santos Farias, Maria Fernanda Vanti Macedo Paulino, Carlos Fernando Macedo, Sofia R. Lieber, Daniela da Silva Camilo, Edilaine G. Guariento, Ana Leda F. Longhini, Gil Guerra, Walkyria Mara Gonçalves Volpini, Letícia Gama e Silva

المصدر: Pediatric Diabetes. 21:606-614

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Adolescent, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Remission, Spontaneous, 030209 endocrinology & metabolism, Disease, Human leukocyte antigen, Gastroenterology, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Gene Frequency, immune system diseases, HLA-DQ Antigens, Internal medicine, Internal Medicine, medicine, Humans, Genetic Predisposition to Disease, 030212 general & internal medicine, Child, Genotyping, HLA-DRB1, Genetic Association Studies, Autoantibodies, Type 1 diabetes, biology, business.industry, Haplotype, Histocompatibility Antigens Class II, Autoantibody, Infant, nutritional and metabolic diseases, medicine.disease, Diabetes Mellitus, Type 1, Haplotypes, Case-Control Studies, Child, Preschool, Pediatrics, Perinatology and Child Health, biology.protein, Female, Antibody, business, Brazil, HLA-DRB1 Chains

الوصف: OBJECTIVE Characterization of partial remission using the insulin dose-adjusted HbA1c (IDAA1c) ≤ 9 definition in a multiethnic Brazilian population of children and adolescents with type 1 diabetes (T1D), in addition with the determination of both Class II HLA genotype and autoantibodies. METHODS We analyzed the prevalence of partial remission in 51 new-onset T1D patients with a median time follow-up of 13 months from diagnosis. For this study, anti-GAD65, anti-IA2 and HLA class II genotyping were considered. RESULTS Partial remission occurred in 41.2% of T1D patients until 3 months after diagnosis, mainly in those aged 5-15 years. We have demonstrated a significant increase in the haplotypes of class II HLA DRB1*0301-DQB1*0201 in children and adolescents with a partial remission phase of the disease (42.9% vs 21.7% in non-remitters, P = .0291). This haplotype was also associated with the reduction of anti-IA2 antibodies production. Homozygote DRB1*03-DQB1*0201/DRB1*03-DQB1*0201 children had the lowest prevalence of IA-2A antibodies (P = .0402). However, this association does not correlate with the time of the remission phase. CONCLUSION Although the number of patients studied was reduced, our data suggested that the association between genetics and decrease in antibody production to certain islet auto-antigen may contribute, at least in part, to the remission phase of T1D.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3ac391ccba4e931b892cb1ef922e328Test
https://doi.org/10.1111/pedi.12999Test

المؤلفون: Paolo Baldissara, Leonardo Ciocca, Dario Melilli, Giuseppe Currò, Candida Parisi, Giuseppe Gallina, Vinícius Felipe Wandscher

المساهمون: Melilli Dario, Wandscher Vinicius Felipe, Ciocca Leonardo, Currò Giuseppe, Parisi Candida, Gallina Giuseppe, Baldissara Paolo, Melilli D., Wandscher V.F., Ciocca L., Curro G., Parisi C., Gallina G., Baldissara P.

المصدر: Brazilian Journal of Oral Sciences, Vol 19 (2020)

مصطلحات موضوعية: Materials science, Root canal, Dentistry, 03 medical and health sciences, 0302 clinical medicine, Settore MED/28 - Malattie Odontostomatologiche, Surface properties, Dentin, medicine, Air abrasion, dental, General Dentistry, Acrylic resin, Denture Retention, Cementation, Cement, Universal testing machine, 030505 public health, Enamel paint, business.industry, Air abrasion, dental cementation. Denture retention. Surface Properties, technology, industry, and agriculture, RK1-715, 030206 dentistry, medicine.anatomical_structure, visual_art, visual_art.visual_art_medium, 0305 other medical science, business, Denture retention, Removable partial denture

الوصف: Aim: To evaluate the retention of an endodontic titanium post with a spherical head for removable partial denture or overdenture attachment according to surface treatment type. Methods: Sixty healthy single-rooted teeth, sectioned at the enamel/cementum junction, were treated endodontically and steadily fixed in the embedding acrylic resin. The titanium posts were subdivided into four groups: control, no surface treatment (Ctrl); posts with macro-retentive grooves (MR); air abrasion of the post surface (AB); and posts with macro-retentive grooves and air abrasion of the post surface (MR+AB). The posts were luted in the root canal using self-adhesive dual resin cement. Pull-out testing was performed using a universal testing machine until complete detachment was achieved. After pull-out testing, the metallic posts were examined under an optical microscope and the failures were classified based on the cement distribution pattern on the extracted posts: 0, no cement left on the post (cement/post failure); 1, post surface partially covered by adhered cement (post/cement and dentin/cement mixed failure); 2, post surface completely covered by cement (dentin/cement failure). The retention data were analyzed by one-way ANOVA, Bonferroni–Dunn test (p

وصف الملف: ELETTRONICO

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::081f881bd5ab3d032bd8d08121602354Test
https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8658798Test

المؤلفون: Vinícius Saura, Alexandre Leme Godoy dos Santos, Rafael Trevisan Ortiz, Maria Cândida Parisi, Túlio Diniz Fernandes, Márcia Nery

المصدر: Acta Ortopédica Brasileira, Vol 18, Iss 3, Pp 148-151 (2010)

مصطلحات موضوعية: Diabetes Melito, Neuropatias diabéticas, Marcha, Diabetes Mellitus, Diabetic neuropathies, Gait, Medicine, Orthopedic surgery, RD701-811

الوصف: OBJETIVO: Analisar a amplitude de movimento do tornozelo e as forças de reação vertical do solo envolvidas na marcha de pacientes portadores de diabetes com e sem neuropatia periférica. CASUÍSTICA E MÉTODO: 36 indivíduos divididos em três grupos: Controle - GC: 10 indivíduos sem diabetes, Diabetes - GD: 10 indivíduos portadores de diabetes sem neuropatia periférica e Neuropatia - GDN: 16 indivíduos portadores de diabetes e neuropatia diabética periférica. Foi realizada análise da marcha - AMTI® OR6/6, e da amplitude de movimento articular tíbio-társica - Sistema Vicom 640® - de todos os participantes. RESULTADOS: O primeiro e segundo pico de força vertical de reação do solo são maiores no grupo Neuropatia e a amplitude de movimento articular do tornozelo é menor nos grupos Diabetes e Neuropatia. CONCLUSÃO: A amplitude de movimento da articulação tíbio-társica está diminuida nos diabetéticos, independente da presença ou ausência de neuropatia periférica, e os diabéticos com neuropatia periférica, apresentaram aumento no primeiro e no segundo pico da força de reação vertical do solo durante a marcha. OBJECTIVE: The purpose of this study was to analyze the range of movement of the ankle and the vertical ground reaction force involved in gait among diabetic patients with and without peripheral neuropathy. SAMPLE AND METHOD: 36 individuals were divided into three groups: Control group - CG: 10 individuals without diabetes, Diabetic group - DG: 10 individuals with diabetes without peripheral neuropathy and Neuropathy, and Diabetic neuropathic group - DNG: 16 individuals with diabetes and peripheral diabetic neuropathy. Gait - AMTI® OR6/6m and range of tibiotarsal joint movement - System Vicom 640® was carried out in all the participants. RESULTS: The first and second vertical ground reaction force peaks were statistically higher in the neuropathy group, and the range of ankle motion was lower in the Diabetes and Neuropathy groups. CONCLUSION: The range of movement of the tibiotarsal joint is lower in diabetics, ...

العلاقة: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-78522010000300006Test; https://doaj.org/toc/1413-7852Test; https://doaj.org/toc/1809-4406Test; https://doaj.org/article/ac466f6497484a9faee214605fd7bdc4Test

الإتاحة: https://doi.org/10.1590/S1413-78522010000300006Test
https://doaj.org/article/ac466f6497484a9faee214605fd7bdc4Test

المؤلفون: Ana Maria Estivalete Marchionatti, Candida Parisi, Leonardo Ciocca, Vinícius Felipe Wandscher, Paolo Baldissara, Carlo Monaco

المساهمون: Baldissara, Paolo, Wandscher, Vinícius Felipe, Marchionatti, Ana Maria Estivalete, Parisi, Candida, Monaco, Carlo, Ciocca, Leonardo

مصطلحات موضوعية: Molar, optical properties, Ceramics, Materials science, Light, Optical Phenomena, Post hoc, Surface Properties, Color, 02 engineering and technology, translucency, zirconia, lithium disilicate, dental ceramics, translucency, optical properties, Dental Materials, 03 medical and health sciences, 0302 clinical medicine, Materials Testing, Humans, Cubic zirconia, Ceramic, Composite material, zirconia, lithium disilicate, dental ceramics, Crowns, 030206 dentistry, Mechanical resistance, 021001 nanoscience & nanotechnology, Dental Porcelain, Toughening, Dental Prosthesis Design, Spectrophotometry, visual_art, visual_art.visual_art_medium, Computer-Aided Design, Contrast ratio, Zirconium, Oral Surgery, Dark chamber, 0210 nano-technology

الوصف: Statement of problem: Although several monolithic zirconia ceramics have recently been introduced, the need for improved optical properties remains. The newest cubic-zirconia has been claimed to have optimal translucency characteristics for esthetic restorations. Purpose: This in vitro study evaluated the optical properties of novel cubic ultratranslucent (UT) and supertranslucent (ST) zirconia by comparing them with lithium disilicate (L-DIS) glass-ceramic for the manufacture of monolithic computer-aided design and computer-aided manufacturing (CAD-CAM) molar crowns. Material and methods: The UT and ST multilayered zirconia and the low-translucency grade L-DIS were milled. Eighty monolithic crowns were made from 2 CAD files, corresponding to thicknesses of 1.0 and 1.5 mm, and subdivided (n=20) into 4 groups: UT1.0, UT1.5, ST1.0, and L-DIS1.5. All groups were shaded using A2 color standard. Translucency of the crowns was measured by total transmission, using a photoradiometer in a dark chamber; furthermore, the contrast ratio was analyzed using a dental spectrophotometer applied to the buccal surface of the crowns. Data were analyzed using the Kruskal-Wallis and post hoc multiple Mann-Whitney U tests with Bonferroni correction (α=.05 divided by the number of tests performed in each set). Results: When the ceramic types were analyzed, using total transmission and contrast methods, they showed significantly different translucency levels: UT1.0>ST1.0>UT1.5>L-DIS1.5 (total transmission P

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73884ab552b84ab4c39ba2c8f2ac7ea8Test
http://hdl.handle.net/11585/674105Test

المؤلفون: Roberto Scotti, Vinícius Felipe Wandscher, Candida Parisi, R. Garcia Fonseca, Leonardo Ciocca, Paolo Baldissara, C. Castelletti

المساهمون: P. Baldissara , C. Parisi, C. Castelletti, R. Scotti, V.F. Wandscher, R. Garcia Fonseca, L. Ciocca

المصدر: Dental Materials. 34:e7-e8

مصطلحات موضوعية: Dental ceramics, Validation study, Materials science, Mechanics of Materials, Fatigue testing, Fatigue cycling, Wear, Zirconia ceramics, General Materials Science, Machine design, General Dentistry, Reliability engineering

الوصف: Purpose/Aim: Fatigue resistance is a crucial factor for the clinical long-term survival of prosthetic restorations. High strength full-contour ceramics combined with CAD/CAM technology showed promising clinical outcomes and lower costs; however, their fatigue resistance was seldom compared to natural teeth. Aim of this study was to validate a fatigue testing machine concept comparing the fatigue survival and the wear patterns of monolithic ceramic crowns to those of sound human teeth. The null hypothesis was that the fatigue resistance and the wear pattern induced by the machine did not differ among the tested groups (alpha=.05) Materials and Methods: Five groups (n=20) of monolithic crowns of different thickness (1.0mm Y-TZP HT, 1.0mm cubic-zirconia UT, 1.5mm cubic-ziconia UT, 1.0mm cubic-zirconia ST, all from Kuraray-Noritake, and 1.5mm lithium-disilicate, L-DIS, from Ivoclar Vivadent) and 20 human sound third molars have been collected and mounted in epoxy-resin cylinders, then subjected to impact fatigue cycles (Ball-Mill). The specimens were analyzed after 10, 20, 30 and 60min cycling, then analyzed every hour until a total time of 480min cycling. Wear and damage analysis was carried out using a stereomicroscope. The material losses (mm3) were calculated (Rhinoceros software) by comparing the digital impressions (Carestream CS3500 scanner) of each specimen at the different time intervals. Gehan-Breslow-Wilcoxon test and Kruskal-Wallis with post-hoc Dunn's test were applied to survival and volume loss data (alpha=.05). Results: After 480min 1.0mm Y-TZP HT showed the highest fatigue resistance, similar (p>0.05) to 1.5mm UT cubic-zirconia and 1.5mm L-DIS. 1.0mm UT cubic-zirconia showed the highest failure rate (p

وصف الملف: ELETTRONICO

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bc6a3b7a9e2d3b5a4e54598b7370294Test
https://doi.org/10.1016/j.dental.2018.08.016Test

المؤلفون: Paolo Baldissara, Roberto Scotti, M. A. Croce, R. Tiozzo, Candida Parisi

المساهمون: R. SCOTTI, R. TIOZZO, C. PARISI, M.A. CROCE, P. BALDISSARA

المصدر: International Endodontic Journal. 41:651-657

مصطلحات موضوعية: Materials science, food.ingredient, Cytotoxicity test, Biocompatibility, Cell Survival, Gingiva, cytotoxicity test, endodontic filler, fibroblasts cultures, resin sealers, Composite Resins, BIOCOMPATIBILITY, Root Canal Filling Materials, CITOTOXICITY ASSAY, food, Humans, Viability assay, Composite material, General Dentistry, Incubation, Cells, Cultured, Chromatography, Anova test, fibroblasts culture, Fibroblasts, Gutta-Percha, Filler (animal food), Ex vivo

الوصف: Aim To evaluate the biocompatibility of a resin-based endodontic filler (RealSeal) using the indirect cytotoxicity test. Methodology Human gingival fibroblasts were cultured ex vivo. Pellets of the materials to be tested were incubated for 24, 48, and 72 h at 37 °C under sterile conditions to obtain their eluates. The fibroblasts were exposed to either diluted (50%) or undiluted eluates for 24 h. A culture medium with foetal calf serum was added to the control wells. Cell viability was estimated by 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide method. The data concerning cell viability were statistically analyzed using one-way anova test and Bonferroni multiple comparisons test. Results Eluates obtained after 24 h of incubation with the resin filler did not reduce cellular viability. An increase in cellular viability, as compared with control cells, was observed in the gutta-percha group. The undiluted eluate from the polyether material was cytotoxic, causing an 82 ± 4% decrease in cellular viability. Eluates obtained after 48 h of incubation with the resin filler increased cellular viability, whereas the polyether significantly reduced viability. Gutta-percha did not cause any detectable change. After 72 h of incubation the eluate of the resin filler caused an increase in cellular viability, as did gutta-percha, whereas polyether caused a significant decrease. Conclusions RealSeal resin filler was nontoxic in this laboratory model. Further investigations are necessary to verify its usefulness in clinical applications.

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1674dc3e656c7b0b17887c8a9fbd16d5Test
https://doi.org/10.1111/j.1365-2591.2008.01403.xTest