المؤلفون: Han Chen, Ardalan Naseri, Degui Zhi

مصطلحات موضوعية: Genetics, Neuroscience, Biotechnology, Evolutionary Biology, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, single nucleotide polymorphisms, simulation studies showed, copy number variations, wide association studies, sequencing association studies, suggestive tag variants, random matrix algorithms, phased haplotype information, variant set tests, uk biobank data, many complex traits, descent mapping test, rare genetic variants, variant tests, complex traits, genetic association, rare variants, random projection, haplotype effects, causal variants, genetic loci, genetic associations, genetic architecture

العلاقة: https://figshare.com/articles/figure/GWAS_and_finite-sample_FiMAP_p_values_from_RaPID_IBD_segments_on_chromosome_21_/24714424Test

الإتاحة: https://doi.org/10.1371/journal.pgen.1011057.g006Test
https://figshare.com/articles/figure/GWAS_and_finite-sample_FiMAP_p_values_from_RaPID_IBD_segments_on_chromosome_21_/24714424Test

المؤلفون: Kang, Eun Yong, Martin, Lisa J., Mangul, Serghei, Isvilanonda, Warin, Zou, Jennifer, Ben-David, Eyal, Han, Buhm, Lusis, Aldons J., Shifman, Sagiv, Eskin, Eleazar

المساهمون: Han, Buhm

مصطلحات موضوعية: FUNCTIONAL VARIATION, GENOME, TRAIT, TRANSCRIPTOME, IMBALANCE, CELLS, Allele specific expression, expression quantitative trait loci, causal variants

العلاقة: Genetics, Vol.204 No.3, pp.1057-1064; https://hdl.handle.net/10371/191570Test; 000388502900019; 2-s2.0-84994881321; 71020

الإتاحة: https://doi.org/10.1534/genetics.115.177246Test
https://hdl.handle.net/10371/191570Test

المؤلفون: Hsueh, Wen-Chi, Nair, Anup K., Kobes, Sayuko, Chen, Peng, Goring, Harald H. H., Pollin, Toni I., Malhotra, Alka, Knowler, William C., Baier, Leslie J., Hanson, Robert L.

المصدر: School of Medicine Publications and Presentations

مصطلحات موضوعية: triglycerides, linkage, replication, American Indians genetics, population studies, causal variants, Genetic Structures, Medicine and Health Sciences

وصف الملف: application/pdf

العلاقة: https://scholarworks.utrgv.edu/som_pub/117Test; https://scholarworks.utrgv.edu/context/som_pub/article/1116/viewcontent/2017__nihms917321.pdfTest

الإتاحة: https://doi.org/10.1161/CIRCGENETICS.117.001809Test
https://scholarworks.utrgv.edu/som_pub/117Test
https://scholarworks.utrgv.edu/context/som_pub/article/1116/viewcontent/2017__nihms917321.pdfTest

المؤلفون: Yao, Chen, Joehanes, Roby, Johnson, Andrew D., Huan, Tianxiao, Liu, Chunyu, Freedman, Jane E., Munson, Peter J., Hill, David A, Vidal, Marc, Levy, Daniel

المساهمون: Department of Medicine, Division of Cardiovascular Medicine, UMass Metabolic Network

المصدر: American journal of human genetics ; 100 ; 4 ; 571-580

مصطلحات موضوعية: GWAS, cardiometabolic traits, causal variants, eQTLs, hotspots, mediation, trans, Cellular and Molecular Physiology, Genetics and Genomics, Molecular Biology

العلاقة: Link to Article in PubMed; https://doi.org/10.1016/j.ajhg.2017.02.003Test; Am J Hum Genet. 2017 Apr 6;100(4):571-580. Epub 2017 Mar 9. Link to article on publisher's site; 0002-9297 (Linking); http://hdl.handle.net/20.500.14038/36705Test; https://escholarship.umassmed.edu/metnet_pubs/73Test; metnet_pubs/73

الإتاحة: https://doi.org/10.1016/j.ajhg.2017.02.003Test
https://doi.org/20.500.14038/36705Test
https://hdl.handle.net/20.500.14038/36705Test
https://escholarship.umassmed.edu/metnet_pubs/73Test

المؤلفون: Ha Vu, Jason Ernst

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Biotechnology & Applied Microbiology, Genetics & Heredity, CHROMATIN-STATE DISCOVERY, DNA METHYLATION, SYSTEMATIC ANNOTATION, POINT MUTATIONS, CAUSAL VARIANTS, ELEMENTS, ORGANIZATION, LANDSCAPE, ENHANCERS, STEM, Chromatin, Epigenomics, Genome, Human, Genomics, Humans, Molecular Sequence Annotation, 31 Biological Sciences, 3102 Bioinformatics and Computational Biology, Biotechnology, Genetics, Human Genome, 1 Underpinning research, 1.1 Normal biological development and functioning, Generic health relevance, Environmental Sciences

العلاقة: http://hdl.handle.net/10779/DRO/DU:23796762.v1Test; https://figshare.com/articles/journal_contribution/Universal_annotation_of_the_human_genome_through_integration_of_over_a_thousand_epigenomic_datasets/23796762Test

الإتاحة: http://hdl.handle.net/10779/DRO/DU:23796762.v1Test
https://figshare.com/articles/journal_contribution/Universal_annotation_of_the_human_genome_through_integration_of_over_a_thousand_epigenomic_datasets/23796762Test

المؤلفون: Constantin Polychronakos, Muhammad Saqib, Asif Mir, Luc Marchand, Ibrar Rafique, Muhammad Naeem

المصدر: BMC Endocrine Disorders
BMC Endocrine Disorders, Vol 21, Iss 1, Pp 1-6 (2021)

مصطلحات موضوعية: Pediatrics, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Consanguinity, Type 2 diabetes, Disease, Sulfonylurea Receptors, Diseases of the endocrine glands. Clinical endocrinology, Maturity onset diabetes of the young, symbols.namesake, Causal variants, Diabetes mellitus, Glucokinase, Genetics, Basic Helix-Loop-Helix Transcription Factors, medicine, Humans, Insulin, Paired Box Transcription Factors, Hepatocyte Nuclear Factor 1-alpha, Potassium Channels, Inwardly Rectifying, Adaptor Proteins, Signal Transducing, Hepatocyte Nuclear Factor 1-beta, Homeodomain Proteins, Sanger sequencing, Autosomal dominant type, business.industry, Diabetes, High-Throughput Nucleotide Sequencing, Lipase, Sequence Analysis, DNA, General Medicine, RC648-665, medicine.disease, HNF1A, Repressor Proteins, src-Family Kinases, Diabetes Mellitus, Type 2, Hepatocyte Nuclear Factor 4, MODY, Trans-Activators, symbols, Apoptosis Regulatory Proteins, business, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79ce2911884cc8960a6a0a3cc21e0b56Test
https://doi.org/10.1186/s12902-021-00891-7Test

المؤلفون: Benner, Christian, Spencer, Chris C. A., Havulinna, Aki S., Salomaa, Veikko, Ripatti, Samuli, Pirinen, Matti

المساهمون: Clinicum, Institute for Molecular Medicine Finland, Samuli Olli Ripatti / Principal Investigator, Department of Public Health, Biostatistics Helsinki, Complex Disease Genetics, Statistical and population genetics

مصطلحات موضوعية: CAUSAL VARIANTS, STATISTICS, IMPUTATION, RISK, 3142 Public health care science, environmental and occupational health

وصف الملف: application/pdf

العلاقة: This work was financially supported by the Doctoral Programme in Population Health (C.B.), the Academy of Finland [257654 and 288509 to M.P.; 251217 and 255847 to S.R.] and a Wellcome Trust Career Development Fellowship to C.C.A.S [097364/Z/11/Z]. S.R. was further supported by the Academy of Finland Center of Excellence for Complex Disease Genetics, EU FP7 projects ENGAGE (201413), BioSHaRE (261433), the Finnish Foundation for Cardiovascular Research, Biocentrum Helsinki and the Sigrid Juselius Foundation.; Benner , C , Spencer , C C A , Havulinna , A S , Salomaa , V , Ripatti , S & Pirinen , M 2016 , ' FINEMAP : efficient variable selection using summary data from genome-wide association studies ' , Bioinformatics , vol. 32 , no. 10 , pp. 1493-1501 . https://doi.org/10.1093/bioinformatics/btw018Test; ORCID: /0000-0002-1664-1350/work/29075051; 84970015769; 3b22b1ef-11bc-48d4-a20b-647ff19cb32a; http://hdl.handle.net/10138/164645Test; 000376656900008

الإتاحة: http://hdl.handle.net/10138/164645Test

المؤلفون: Xiaoqing Cheng (8685924), Fenglan Zhang (4984496), Jingwen Gong (4046288), Yige Li (10176194), Dan Zhou (29408), Jing Wang (6206297), Eu Gene Vong (12035467), Ying Yuan (133529), Maode Lai (15338), Dandan Zhang (228849)

مصطلحات موضوعية: Biochemistry, Genetics, Molecular Biology, Biotechnology, Immunology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, wide association studies, strong linkage disequilibrium, promising therapeutic target, 160 susceptibility loci, specific enhancer activity, modulating enhancer activity, putative functional variant, eqtl association data, comprehensive functional annotation, related gwas signals, div >< p, 1 might serve, potential causal variants, potential functional variants, crc susceptibility snps, functional annotation, functional variants, regulatory potential, crc activity

العلاقة: https://figshare.com/articles/dataset/CRC-related_loci_associated_with_chromatin_accessibility_/19110568Test

الإتاحة: https://doi.org/10.1371/journal.pgen.1010050.s009Test

المؤلفون: Xiaoqing Cheng (8685924), Fenglan Zhang (4984496), Jingwen Gong (4046288), Yige Li (10176194), Dan Zhou (29408), Jing Wang (6206297), Eu Gene Vong (12035467), Ying Yuan (133529), Maode Lai (15338), Dandan Zhang (228849)

مصطلحات موضوعية: Biochemistry, Genetics, Molecular Biology, Biotechnology, Immunology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, wide association studies, strong linkage disequilibrium, promising therapeutic target, 160 susceptibility loci, specific enhancer activity, modulating enhancer activity, putative functional variant, eqtl association data, comprehensive functional annotation, related gwas signals, div >< p, 1 might serve, potential causal variants, potential functional variants, crc susceptibility snps, functional annotation, functional variants, regulatory potential, crc activity

العلاقة: https://figshare.com/articles/dataset/The_significant_eQTL_SNPs_in_sigmoid_and_transverse_colon_tissues_from_GTEx_/19110565Test

الإتاحة: https://doi.org/10.1371/journal.pgen.1010050.s008Test

المؤلفون: Xiaoqing Cheng (8685924), Fenglan Zhang (4984496), Jingwen Gong (4046288), Yige Li (10176194), Dan Zhou (29408), Jing Wang (6206297), Eu Gene Vong (12035467), Ying Yuan (133529), Maode Lai (15338), Dandan Zhang (228849)

مصطلحات موضوعية: Biochemistry, Genetics, Molecular Biology, Biotechnology, Immunology, Cancer, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, wide association studies, strong linkage disequilibrium, promising therapeutic target, 160 susceptibility loci, specific enhancer activity, modulating enhancer activity, putative functional variant, eqtl association data, comprehensive functional annotation, related gwas signals, div >< p, 1 might serve, potential causal variants, potential functional variants, crc susceptibility snps, functional annotation, functional variants, regulatory potential, crc activity

العلاقة: https://figshare.com/articles/figure/Luciferase_reporter_assays_of_two_PREs_containing_candidate_functional_SNPs_/19110595Test

الإتاحة: https://doi.org/10.1371/journal.pgen.1010050.g003Test