المؤلفون: R. J. C. M. F. de Kleijn, L. Schropp, J. Westerink, M. Nijkeuter, J. van Laanen, J. Teijink, C. Ünlu, A. W. F. Vos, E. S. van Hattum, B. J. Petri, G. J. de Borst

المصدر: Frontiers in Surgery, Vol 9 (2022)

مصطلحات موضوعية: upper extremity deep venous thrombosis, UEDVT, venous thoracic outlet syndrome, first rib resection and scalenectomy, anticoagulation therapy, Surgery, RD1-811

الوصف: IntroductionCurrent treatment strategies for primary upper extremity deep venous thrombosis (pUEDVT) range from conservative treatment with anticoagulation therapy to invasive treatment with thoracic outlet decompression surgery (TOD), frequently combined with catheter directed thrombolysis, percutaneous transluminal angioplasty, or stenting. Due to a lack of large prospective series with uniform data collection or a randomized trial, the optimal treatment strategy is still under debate. We conducted a multicenter observational study to assess the efficacy and safety of both the conservative and invasive treatment strategies for patients with pUEDVT.MethodsWe retrospectively collected data from patients treated in five vascular referral and teaching hospitals in the Netherlands between 2008 and 2019. Patients were divided into a conservative (Group 1), an invasive treatment group (Group 2) and a cross-over group (Group 3) of patients who received surgical treatment after initial conservative therapy. Follow-up consisted of outpatient clinic visits and an electronic survey. Primary outcome was symptom free survival defined as absence of any symptom of the affected arm reported at last follow-up regardless of severity, or extent of functional disability. Secondary outcomes were incidence of bleeding complications, recurrent venous thromboembolism, surgical complications, and reinterventions.ResultsA total of 115 patients were included (group 1 (N = 45), group 2 (N = 53) or group 3 (N = 27). The symptom free survival was 35.6%, 54.7% and 48.1% after a median follow-up of 36, 26 and 22 months in groups 1, 2 and 3 respectively. Incidence of bleeding complications was 8.6%, 3.8% and 18.5% and recurrent thrombosis occurred in 15.6%, 13.2% and 14.8% in groups 1–3 respectively.ConclusionIn this multicenter retrospective observational cohort analysis the conservative and direct invasive treatments for pUEDVT were deemed safe with low percentages of bleeding complications. Symptom free survival was highest in the direct surgical treatment group but still modest in all subgroups. Perioperative complications were infrequent with no related long term morbidity. Of relevance, pUEDVT patients with confirmed VTOS and recurrent symptoms after conservative treatment may still benefit from TOD surgery. However, symptom free survival of this delayed TOD seems lower than direct surgical treatment and bleeding complications seem to occur more frequently.

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fsurg.2022.1080584/fullTest; https://doaj.org/toc/2296-875XTest

الوصول الحر: https://doaj.org/article/909cdad63f27412bb08e4906c3bb2274Test

المؤلفون: P. Kuru Bektaşoğlu, A.T. Arıkök, B.İ. Ergüder, M.F. Sargon, S. Akyıldız Altun, C. Ünlüer, A. Börekci, H. Kertmen, E. Çelikoğlu, B. Gürer

المصدر: Brain and Spine, Vol 1, Iss , Pp 100801- (2021)

مصطلحات موضوعية: Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2772529421008018Test; https://doaj.org/toc/2772-5294Test

الوصول الحر: https://doaj.org/article/5b69968254d34ffa9df29021cf012753Test

المؤلفون: C. Ünlü, H. Jafari, D. Baleanu

المصدر: Abstract and Applied Analysis, Vol 2013 (2013)

مصطلحات موضوعية: Mathematics, QA1-939

الوصف: A modification of the variational iteration method (VIM) for solving systems of nonlinear fractional-order differential equations is proposed. The fractional derivatives are described in the Caputo sense. The solutions of fractional differential equations (FDE) obtained using the traditional variational iteration method give good approximations in the neighborhood of the initial position. The main advantage of the present method is that it can accelerate the convergence of the iterative approximate solutions relative to the approximate solutions obtained using the traditional variational iteration method. Illustrative examples are presented to show the validity of this modification.

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1085-3375Test; https://doaj.org/toc/1687-0409Test

الوصول الحر: https://doaj.org/article/096d24eaaf354cb59d7d92c8434b34d8Test

المؤلفون: A. Dogru, C. Unlu, E. Tukenmez Tigen, E.N. Koltka, M. Gura

المصدر: Japanese Journal of Infectious Diseases. 2014, 67(1):5

المؤلفون: A. Salfelder, R. P. Lueken, C. Bormann, A. Gallinat, C. P. Moeller, D. Busche, W. Nugent, E. Krueger, A. Nugent, G. Caglar, Y. Tasci, F. Kayikcioglu, A. Haberal, Th. Hasskamp, M. Krichbaum, N. Aka, G. Köse, G. Sabah, E. S. Sayharman, P. Kumru, K. Karaca, B. Haydardedeoglu, E. Simsek, E. Kilicdag, E. Tarim, T. Bagis, F. S. Dede, B. Dilbaz, H. Dede, A. K. Ilhan, S. Oral, A. Erten, I. E. Ertas, S. Kahyaoglu, I. Turgay, M. Tug, S. Kalyoncu, S. Batioglu, G. Zorlu, C. Arici, M. E. Akar, E. S. Ari, E. Ari, O. U. Erbay, M. O. Caliskan, M. Simsek, O. Taskm, Il. Gümüs, N. O. Turhan, G. Arikan, A. Giuliani, S. Kelekci, Z. Yorgancioglu, B. Yilmaz, L. Yasar, K. Savan, S. Sonmez, C. Kart, M. Vural, H. A. Tanriverdi, E. Cinar, A. Barut, K. Özbay, T. Yardim, B. Demir, N. Kilinc, T. Gul, A. C. Erden, M. K. Kokanali, E. B. Kilicdag, E. Aslan, M. Seval, S. Taskin, B. Özmen, K. Kahraman, A. Yarci, T. Tasci, C. Unlü, M. Gözükücük, S. Kurt, E. A. Bozaci, F. Ortac, A. S. Sönmez, A. G. Zebitay, N. Gezer, H. F. Yazicioglu, G. Mehmetoglu, M. Kocak, Y. L. Algül, J. Ozcan, O. Duman, F. Yazicioglu, Y. Sensoy, S. Koc, Z. Cebi, J. Özcan, S. Sönmez, I. Mendilcioglu, M. Özekinci, M. Ulukus, E. C. Ulukus, Y. Seval, O. Cinar, W. Zheng, A. Arici, L. Erkan, F. Soylu, O. Tatli, V. Ozkent, A. R. Dogan, I. Gün, E. Erdemoglu, H. Sargin, M. Kamaci, F. Sendag, L. Akman, S. Yucebilgin, N. Karadadas, K. Oztekin, O. Bilgin, S. Topuz, E. Cigerli, C. A. Iyibozkurt, E. S. Akhan, H. Saygili, S. Berkman, I. Bezircioglu, E. Karakaya, N. Baran, A. Baloglu, C. Aydin, N. Hizli, B. Cetinkaya, A. Kavas, K. Cukurova, A. Köksal, H. Yetimalar, A. Yildiz, H. Ivit, A. Keklik, F. Pinar, N. Tosun, T. Tuncel, K. Boynukalin, M. C. Salman, O. Ozyuncu, G. Bozdag, A. Ayhan, U. Ates, T. Usta, A. Seyhan, B. Ata, B. Sidal, O. T. Guler, S. Esin, S. Guven, A. Gürban, G. Gürban, S. Özen, A. Kirecci, B. Özkesici, S. Yücel, N. Süer, C. E. Erdemoglu, S. E. Akhan, I. Citil, C. Iyibozkurt, M. D. Kesim, A. Atis, Y. Aydin, D. Özpak, F. Tashan, S. Zeteroglu, A. Kolusari, H. Altunay, H. G. Sahin, O. Erol, S. Sarici, B. S. Dingiloglu, T. Güngör, B. Özdal, S. Cavkaytar, Ü. Bilge, L. Mollamahmutoglu, Konca M. Toprak, S. Özsoy, N. Hekim, E. Özel, M. Senates, C. Yener, N. Göker, E. Caliskan, T. Filiz, G. Yucesoy, E. Coskun, B. Vural, A. Corakci, M. A. Narin, M. M. Meydanli, B. Yildizbas, G. Bolluk, B. Ozdemir, B. S. Ünlü, H. Aytan, S. Evsen, Ö L. Tapisiz, S. Zergeroglu, A. Guler, M. M. Altay, A. Can, A. Ungormus, A. Polat

المصدر: Archives of Gynecology and Obstetrics. 271:S69-S86

مصطلحات موضوعية: Obstetrics and Gynecology, General Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::235e51ce6aa97f4f3efb5f8e2d7576f0Test
https://doi.org/10.1007/bf02954776Test

المؤلفون: C. Tekcan, M. M. Naki, N. Özcan, M. Cebi, F. Kanadikirik, R. Has, M. Aydoadu, J. P. Frenz, W. Schröder, F. S. Dede, E. E. Kovalak, O. Gelisen, H. Dede, B. Sariisik, A. Haberal, E. Caliskan, E. Turkoz, A. Corakci, S. Ozeren, I. Yucesoy, N. Terzioglu, W. Köhler, A. Feige, J. Atad, R. Auslender, M. Bardicef, I. Calderon, E. Leron, H. Abramovici, I. F. Ertas, S. Kahyaoglu, M. Turgay, N. Sut, B. Yilmaz, M. Ozel, N. Danisman, I. Kocak, C. Üstün, E. Bese, M. Ingec, B. Borekci, M. Yilmaz, S. Kadanali, F. Erdogan, Y. Kumtepe, I. I. Gümüs, N. O. Turhan, E. Tamburaci, O. Gunduz, M. Akar, M. Simsek, G. Zorlu, O. Balci, K. Gezginc, A. Acar, C. Akyürek, A. Biri, I. Guler, O. Himmetoglu, M. Y. Karaoguz, Sevim Balci, H. A. Tanriverdi, D. Usal, E. Cinar, A. Barut, B. Pilanci, A. Imren, D. Öztekin, S. Kurt, S. Tinar, N. Canoruc, A. Kale, E. Kale, A. Yalinkaya, N. Akdeniz, M. Gol, B. Tuna, S. Guclu, S. Altunyurt, N. Demir, B. Ciftci, E. Senol, S. Haznedarohlu, K. Gucuyener, R. Gursoy, I. Turgay, M. Gocmen, R. Neslihanoglu, M. K. Kokanali, C. Kunt, E. G. Yapar, S. Taskin, A. Yarci, E. A. Bozaci, C. Atabekoglu, F. Söylemez, M. Seval, B. Özmen, S. Mammadova, C. Unlü, D. Güleryüz, Ö. Sahincioglu, N. Öztürk, S. Yalvac, A. Erten, I. Dölen, A. Gul, A. Cebeci, A. Gedikbasi, O. Erol, Y. Ceylan, A. I. Tekirdag, M. A. Onan, A. Turp, M. Kurdoglu, G. Gunaydin, Z. Kurdoglu, A. Erdem, O. Tulumbaci, S. Turkoglu, B. Boyaci, M. B. Tiras, O. Kadayifci, S. C. Demir, I. F. Ürünsak, T. Özgünen, I. C. Evrüke, A. B. Güzel, I. F. Urünsak, A. Uckuyu, E. E. Ozcimen, O. Nisanoglu, F. Yanik, S. Akgun, E. Kuscu, N. C. Sayin, M. T. Canda, N. Ahmet, I. Kurt, F. G. Varol, S. Erkanli, K. Caliskan, T. Bagis, E. Kilicdag, E. Tarim, L. Tutuncu, N. Ardic, E. Mungen, A. R. Ergur, Y. Z. Yergok, N. Cölcimen, H. G. Sahin, M. Kamaci, I. Bezircioglu, M. Bicer, D. Uysal, S. Yigit, A. Baloglu, L. Karci, F. Ozder, A. Yüksel, S. Büyükkurt, B. Tatli, I. Kalelioglu, M. D. Kesim, Y. Aydin, A. Atis, A. Gezer, S. Erkan, Y. Simsek, N. Kahraman, S. Uludag, T. Altinok, M. Erdemoglu, Y. Ozcan, G. Köse, T. Tuncel, N. Aka, P. Kumru, M. A. Güven, P. Ciragil, E. Ozdemir, E. Aktan, K. Bozkurt, M. Kilinc, H. Ekerbicer, S. Ceylaner, G. Ceylaner, D. Gul, E. Ertas, C. Batukan, A. Ozbek, G. Demirpolat, M. Uzel, A. Basaran, G. Bozdag, S. Dagdelen, A. Gürlek, S. Beksac, Özkan A. Arici, T. Isparta, F. C. Dikis, S. B. Civas, C. Ispahi, I. K. Kalelioalu, E. Gilbaz, L. Ibrahimoglu, H. Ermis, A. Yildirim, B. Dane, M. Yayla, C. Dane, M. Özek, I. K. Kalelioglu, Dane Cem, Dural Salih, A. Cetin, M. Kiray, E. Ataoglu, Y. Döventas, H. Delier, A. Yildiz, A. Köksal, N. Celik, H. Yetimalar, A. Keklik, H. Ivit, K. Cukurova, D. Hizli, S. Dilbaz, N. Acer, S. Deveci, B. Dilbaz, S. Yilmaz, Bulbul M. Bicer, E. Karakaya, M. Pehlivan, E. Doger, C. Duman, G. Turker, Y. Cakiroglu, S. Ozkan, D. Dundar, S. Caliskan, V. Aksakalli, G. Önal, B. Ö. Demirkaya, M. Yavuz, T. Bozkurt, O. Ozyuncu, M. C. Salman, T. Durukan, L. Onderoglu, O. Deren, A. Ayhan, C. Tufekci, H. Karalök, E. Ilter, L. Cil, A. E. Karalök, H. Akyol, Ö. Oruc, M. Ekin, M. Ülku, P. Caglar, C. Demirel, T. Güngör, L. Mollamahmutoglu, T. Usta, B. Özdemir, U. Ates, N. Numanoglu, A. Seyhan, B. Sidal, B. Ozdemir, S. Ortakuz, A. Öztarhan, O. Dogan, S. Ilbaz, A. Tarcan, A. Sivaslioglu, V. Akbulut, H. Sade, A. Dede, M. Özel, S. Günaydin, U. Atmaca, B. Ata, S. Akar, B. Vural, S. Özkan, P. Costur, H. Dalcik, S. Filiz, I. Yücesoy, E. Erdemoglu, A. Kolusari, A. V. Sahin, A. Tas, C. Dalcik, G. Yücesoy, E. Unlubilgin, B. Demir, M. Sonmezer, M. Erdem, S. Gezer, Ü. Bayar, F. Demir, O. Api, E. Aygün, B. Kars, B. Cengizoglu, S. Bulut, C. Turan, O. Unal, O. Ünal, Y. K. Karageyim, O. Balcik, Ö. Kara, U. Dogance, A. Akil, M. Api, D. Balsak, M. E. Avci, B. Elveren, M. Hanhan, K. Kayhan, B. Özdal, S. Cavkaytar, M. Özat, O. Aksakal, E. Ozdas, T. Filiz, E. Asian, B. Haydardedeoglu, E. Simsek, F. Bolat, S. Ocak, S. Zeteroglu, A. Deveci, A. Gungoren, E. Borazan, A. Hakverdi, A. Andi

المصدر: Archives of Gynecology and Obstetrics. 271:S1-S32

مصطلحات موضوعية: medicine.medical_specialty, business.industry, Obstetrics, Obstetrics and Gynecology, Medicine, General Medicine, business, Human genetics, Maternal-fetal medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::b9e63836b490efffe7374f3f11dafda4Test
https://doi.org/10.1007/bf02954772Test

المؤلفون: İdris Koçak, C Unlü, R Aytaç, Cem Demirel, C Ustün

المساهمون: Ondokuz Mayıs Üniversitesi

المصدر: Journal of Obstetrics and Gynaecology. 21:187-191

مصطلحات موضوعية: Agonist, medicine.medical_specialty, medicine.drug_class, business.industry, medicine.medical_treatment, media_common.quotation_subject, Obstetrics and Gynecology, medicine.disease, Polycystic ovary, Anovulation, Endocrinology, Internal medicine, Follicular phase, medicine, Endocrine system, Ovulation induction, business, Ovulation, Hormone, media_common

الوصف: We performed a prospective study to assess the effects of a starting dose of 50 units of recombinant follicle stimulating hormone (Puregon) during gonadotrophin-releasing hormone agonist therapy (Suprecur) on follicular development in patients with clomiphene citrate-resistant polycystic ovary syndrome (PCOS). In a prospective clinical trial, 25 women with clomiphene citrate-resistant PCOS who wanted to become pregnant were treated by a low-dose step-up protocol of SC recombinant follicle stimulating hormone administration during gonadotrophin-releasing hormone agonist therapy, monitored by transvaginal ultrasonography and retrospectively by serum endocrine assays taken at each monitoring visit. Cancellation of cycles, ovulation, rate and size of follicles growth, serum E2 concentration and pregnancy were recorded. All patients exhibited a response: 22 patients ovulated, of whom 10 conceived. Using the low-dose protocol during gonadotrophin-releasing hormone agonist therapy permitted induction of ovulation safely and successfully in patients with clomiphene citrate-resistant PCOS who were patients previously difficult to treat with the conventional ovulation induction protocol.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f12cc57beb2f57dc8f0a56bc6b0d38d4Test
https://doi.org/10.1080/01443610020026182Test

المؤلفون: S M M, de Castro, P, Joosse, C, Unlü, E P H, Steller

المصدر: Emergency medicine journal : EMJ. 26(11)

مصطلحات موضوعية: Tibial Fractures, Jogging, Fractures, Stress, Humans, Female, Middle Aged, Osteoarthritis, Knee, Arthralgia, Magnetic Resonance Imaging

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::f52e43558ab7c7478c608f8609d804deTest
https://pubmed.ncbi.nlm.nih.gov/19850807Test

المؤلفون: C, Unlü, S, Böhmer, D H, Maas

المصدر: Fortschritte der Medizin. 108(23)

مصطلحات موضوعية: Male, Humans, Female, Fertilization in Vitro, Antigens, Embryo Transfer, Infertility, Female, Spermatozoa, Zona Pellucida

الوصف: Immunologic disturbances must be considered a major cause of unexplained infertility. To evaluate the influence of sperm antibodies (SPAB) and zona pellucida antibodies (ZPAB) on the pregnancy rate, we have screened patients treated by in-vitro fertilization (IVF) and embryo transfer (ET) in the Department of Obstetrics and Gynecology of the School of Medicine, Hannover, for the presence of sperm antibodies and zona pellucida antibodies in the serum, cervical mucus and uterine secretions, and also in the serum and ejaculate of the husbands. After embryo transfer the concentrations of progesterone and beta-hCG in the sera were determined to evaluate the luteal phase and to detect early pregnancy. Among 122 women 11 clinical pregnancies were achieved; 8 of these pregnant women showed negative antibody reactions, while only 3 women with significant positive reactions for SPAB or ZPAB became pregnant. Only one pregnancy occurred in 24 women with high ZPAB titers. In conclusion, determinations of SPAB- and ZPAB-titers in serum and genital secretions are highly recommended in the evaluation of infertile couples.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::f0ae90af4f934691e48b42fcb309384cTest
https://pubmed.ncbi.nlm.nih.gov/2210581Test

المؤلفون: S, Böhmer, F, Degenhardt, C, Unlü, K, Jagla, W, Bader

المصدر: Zeitschrift fur Geburtshilfe und Perinatologie. 194(3)

مصطلحات موضوعية: Postoperative Complications, Pregnancy, Suture Techniques, Infant, Newborn, Humans, Female, Uterine Cervical Incompetence, Cervix Uteri, Ultrasonography

الوصف: Up to now postoperative control of the uterine cervix following cerclage was performed by bimanual palpation. Since clinical use of transvaginal sonography it is possible to get objective results about preoperative morphology of the cervix (exact cervical length, dilatation of the cervical canal and opening of internal and external os). Besides postoperative vaginal sonography following cerclage can ascertain lengthening and stabilization of the incompetent cervix and localize the ligature's position. 75 pregnant women between 15th and 30th week of gestation were examined using a 5-MHz vaginal sector scanner probe following Shirodkar cerclage to gain information about the residual cervical length and the distance from the surface of the ectocervix to the ligature's position within the anterior and posterior lip of the cervix. The mean postoperative cervical length was 3.75 cm (1.5 cm-6.5 cm). Compared to the preoperative average length of 3.0 cm (0.5 cm-5.0 cm) the cerclage resulted in an increase of about 25%. The average distance from the surface of the ectocervix to the ligature at anterior lip of the cervix was 1.85 cm, ranging from 0.9 cm to 2.6 cm. The mean value at the posterior lip was 1.56 cm, ranging from 0.8 cm to 2.0 cm. This study showed that the actual positions of ligatures after cerclage operations varied very much. Unsatisfying position can be an explanation why some preterm deliveries can not be prevented. Therefore it is recommended to control the position of the cerclage ligation postoperatively using transvaginal sonography.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::b16cbd8f74c0c5dfa8e6a0a44d161661Test
https://pubmed.ncbi.nlm.nih.gov/2198725Test