المؤلفون: Gras-Valentí, Paula, Mora-Muriel, Juan G., Chico-Sánchez, Pablo, Algado-Sellés, Natividad, Soler-Molina, Victor M., Hernández-Maldonado, María, Lameiras-Azevedo, Ana S., Jiménez Sepúlveda, Natali J., Gómez Sotero, Isel L., Villanueva-Ruiz, César O., Barrenengoa-Sañudo, Julio, Fuster-Pérez, Marina, Cánovas-Jávega, Sandra, Cerezo-Milan, Patricia, Monerris-Palmer, Miranda, Llorens-Soriano, Pere, Merino-Lucas, Esperanza, Rodríguez-Diaz, Juan C., Gil-Carbonell, Joan, Sánchez-Martínez, Rosario, Pastor-Cesteros, Rogelio, Mena-Esquivias, Luis, Galiana-Ivars, Maria, Jaime-Sánchez, Francisco A., Margarit-Ferri, Cesar, Gonzalez-deDios, Javier, Lloret, German, García-Alonso, Miguel A., Sánchez-Vela, Pablo, Sánchez-Payá, José

المصدر: Journal of Patient Safety ; volume 17, issue 4, page 323-330 ; ISSN 1549-8425 1549-8417

الوصف: Background Although recommendations to prevent COVID-19 healthcare-associated infections (HAIs) have been proposed, data on their effectivity are currently limited. Objective The aim was to evaluate the effectivity of a program of control and prevention of COVID-19 in an academic general hospital in Spain. Methods We captured the number of COVID-19 cases and the type of contact that occurred in hospitalized patients and healthcare personnel (HCP). To evaluate the impact of the continuous use of a surgical mask among HCP, the number of patients with COVID-19 HAIs and accumulated incidence of HCP with COVID-19 was compared between the preintervention and intervention periods. Results Two hundred fifty-two patients with COVID-19 have been admitted to the hospital. Seven of them had an HAI origin (6 in the preintervention period and 1 in the intervention period). One hundred forty-two HCP were infected with SARS-CoV-2. Of them, 22 (15.5%) were attributed to healthcare (2 in the emergency department and none in the critical care departments), and 120 (84.5%) were attributed to social relations in the workplace or during their non–work-related personal interactions. The accumulated incidence during the preintervention period was 22.3 for every 1000 HCP and 8.2 for every 1000 HCP during the intervention period. The relative risk was 0.37 (95% confidence interval, 0.25 to 0.55) and the attributable risk was −0.014 (95% confidence interval, −0.020 to −0.009). Conclusions A program of control and prevention of HAIs complemented with the recommendation for the continuous use of a surgical mask in the workplace and social environments of HCP effectively decreased the risk of COVID-19 HAIs in admitted patients and HCP.

الإتاحة: https://doi.org/10.1097/pts.0000000000000852Test

المؤلفون: Algado-Sellés, Natividad, Gras-Valentí, Paula, Chico-Sánchez, Pablo, Mora-Muriel, Juan G., Soler-Molina, Victor M., Hernández-Maldonado, María, Lameiras-Azevedo, Ana-Sofía, Jiménez-Sepúlveda, Natali J., Gómez-Sotero, Isel-Lilibeth, Villanueva-Ruiz, Cesar O., Barrenengoa-Sañudo, Julio, Fuster-Pérez, Marina, Cánovas-Javega, Sandra, Cerezo-Milan, Patricia, Monerris-Palmer, Miranda, Esclapez, Ana, Cartagena-Llopis, Lidia, García-Rivera, Claudia, Martínez-Tornero, Iluminada, Nadal-Morante, Verónica, Merino-Lucas, Esperanza, Rodriguez-Diaz, Juan C., Vidal-Catala, Inmaculada, Llorens-Soriano, Pere, San Inocencio, David, Gil-Carbonell, Joan, Montiel-Higuero, Inés, Sánchez-Vela, Pablo, Sánchez-Payá, José

المصدر: American Journal of Preventive Medicine ; volume 59, issue 6, page e221-e229 ; ISSN 0749-3797

مصطلحات موضوعية: Public Health, Environmental and Occupational Health, Epidemiology

الإتاحة: https://doi.org/10.1016/j.amepre.2020.07.014Test
https://api.elsevier.com/content/article/PII:S0749379720303494?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0749379720303494?httpAccept=text/plainTest

المؤلفون: Algado-Sellés, Natividad, Gras-Valentí, Paula, Mora-Muriel, Juan Gabriel, Chico-Sánchez, Pablo, Fuster-Pérez, Marina, Canovas-Javega, Sandra, Villanueva-Ruiz, Cesar O., Leutscher-Vasen, Edith, Lameiras-Azevedo, Ana S., Hernandez-Maldonado, Maria, Jimenez-Sepulveda, Natali J., Sanchez-Paya, Jose

المصدر: Infection Control & Hospital Epidemiology ; volume 41, issue S1, page s231-s232 ; ISSN 0899-823X 1559-6834

مصطلحات موضوعية: Infectious Diseases, Microbiology (medical), Epidemiology

الوصف: Background: Hand hygiene (HH) is the most important measure for preventing healthcare-associated infections. The objective is to gain insight into the evolution of the degree of compliance with recommendations (DCR) on HH and its associated factors in the surgical areas of a tertiary-care hospital. Methods: This observational, cross-sectional study, was repeated over time, with direct observation of the DCR on HH during the daily activity of healthcare workers in surgical areas: general surgery, urology, vascular surgery, traumatology, neurosurgery, thoracic surgery, heart surgery, pediatric surgery, otorhinolaryngology, gynecology and obstetrics, ophthalmology. Over 14 years (from 2005 to 2018), 15,946 HH opportunities were registered, together with different additional variables (age, sex, professional position, surgical area ). The 2 test was used to study the association and the crude, and adjusted odds ratios were used to quantify its magnitude. Results: The DCR on HH in surgical areas was 49.7% (95% CI, 48.9%–50.5%), and in the group of nonsurgical areas it was 53.4% (95% CI, 53.1%–54.1%). The area with the highest degree of compliance was urology (56.7%; 95% CI, 53.9%–59.6%), and the area with the lowest degree of compliance was traumatology (43.3%; 95% CI, 40.4%–46.2%). Some associated factors were the indications after an activity has been performed (58.6%; aOR, 2.7; 95% CI, 2.5–2.9) and the availability of pocket-size alcohol-based disinfectant (63.8%; aOR, 2.4; 95% CI, 2.2–2.5). Conclusions: The DCR on HH in surgical areas is lower than in other hospital areas, and there is still some margin for improvement. We have identified some modifiable factors that have an independent association with HH compliance in surgical areas. Focusing on them will increase compliance with HH with the ultimate goal of reducing healthcare-associated infections. Funding: None Disclosures: None

الإتاحة: https://doi.org/10.1017/ice.2020.781Test
https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0899823X20007813Test

المؤلفون: Chico-Sánchez, Pablo, Canovas-Javega, Sandra, Jimenez-Sepulveda, Natali J., Leutscher-Vasen, Edith, Villanueva-Ruiz, Cesar O., Benito-Miralles, Carmen M., Hernandez-Maldonado, Maria, Lameiras-Azevedo, Ana S., Sanchez-Paya, Jose

المصدر: Infection Control & Hospital Epidemiology ; volume 41, issue S1, page s206-s207 ; ISSN 0899-823X 1559-6834

مصطلحات موضوعية: Infectious Diseases, Microbiology (medical), Epidemiology

الوصف: Background: Pseudomonas aeruginosa , is the third etiologic agent of healthcare associated infections, and the most frequent pathogen in ventilator-associated pneumonia (VAP). In critical care units is associated with high mortality, long hospital stay, and high healthcare-associated costs. We evaluated the effectiveness of filter placement in the water taps in critical care units to prevent the occurrence of healthcare-associated infections (HAIa) by Pseudomonas aeruginosa . Methods: This experimental study was both cross-over and open-label in nature. We included patients admitted for >24 hours in critical care units over 24 months. The study was divided into 4 periods of 6 months each. We divided the study into 2 groups: patients in units with filters and patients in units without filters. We compared the incidence density of P. aeruginosa HAIs (number of cases divided by the number of person days) according the ECDC definition of case criteria between the groups. The 2 test was used, and the magnitude of the association was calculated as a rate ratio with a 95% confidence interval, adjusted using a Poisson regression model. Results: Overall, 1,132 patients were included in the study: 595 in units with water tap filters and 537 in units without water tap filters. HAI incidence among patients in units with water tap filters was 5.3 per 1,000 person days stay; without water tap filters, HAI incidence was 4.7 per 1,000 person days stay (HR, 0.94; 95% CI, 0.47–1.90). Conclusions: The preliminary results of this study indicate a a lower incidence of P. aeruginosa HAIs in units with filters placed in water taps than in units without filters. Disclosures: None Funding: None

الإتاحة: https://doi.org/10.1017/ice.2020.749Test
https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0899823X20007497Test

المؤلفون: Chico-Sánchez, Pablo, Mora-Muriel, Juan Gabriel, Gras-Valentí, Paula, Jimenez-Sepulveda, Natali J., Algado-Sellés, Natividad, Gomez-Sotero, Isel, Soler, Victor, Esclapez-Martinez, Ana, Canovas-Javega, Sandra, Sanchez-Paya, Jose

المصدر: Infection Control & Hospital Epidemiology ; volume 41, issue S1, page s84-s85 ; ISSN 0899-823X 1559-6834

مصطلحات موضوعية: Infectious Diseases, Microbiology (medical), Epidemiology

الوصف: Background: Annual flu vaccination is the most effective way to prevent the disease and its complications. Vaccine effectiveness (EV) varies from season to season, requiring annual re-evaluation. The objective of this study was to estimate the preliminary effectiveness of the influenza vaccine until epidemiological week 4 of the 2019–2020 season, in patients admitted to a tertiary-level hospital. Method : We conducted a case-control study at University General Hospital, Alicante, Spain, during the 2019–2020 season. We included all patients hospitalized with influenza confirmed by laboratory test (ie, PCR positive for influenza) during the period between epidemiological week 40 of 2019 and epidemiological week 4 of 2020. These were considered cases, and those with clinical suspicion of influenza and negative RT-PCR were considered controls. Vaccination coverage was calculated in cases and in controls, determining the odds ratio. We calculated the vaccine effectiveness (VE) and its 95% confidence interval using the following formula: VE = (1 − odds ratio) ×100. Result : We included 545 patients: 61 cases and 484 controls. The overall EV for influenza cases prevention was 40.7% (95% CI, −17.1 to 70.1), and for those >1 year of age, the overall EV was 56.9% (95% CI, 13.9–78.5). Conclusion: The 2019–2020 Influenza vaccine was effective in preventing influenza cases in patients admitted up to week 4 of the 2019–2020 season. These results are preliminary and may vary; they should be re-evaluated at the end of the season. Funding: None Disclosures: None

الإتاحة: https://doi.org/10.1017/ice.2020.579Test
https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0899823X20005796Test

المؤلفون: Chico-Sánchez, Pablo, Gras-Valentí, Paula, Algado-Sellés, Natividad, Jiménez-Sepúlveda, Natali Juliet, Rodríguez-Díaz, Juan Carlos, Merino-Lucas, Esperanza, Galiana-Ivars, María, Fuster-Pérez, Marina, Cartagena-Llopis, Lidia, Balboa Esteve, Sonia, Cánovas-Jávega, Sandra, Esclapez-Martínez, Ana, Monerris-Palmer, Miranda, Cerezo-Millán, Patricia, Sánchez-Payá, José, Ronda-Pérez, Elena

المساهمون: Universidad de Alicante. Departamento de Enfermería Comunitaria, Medicina Preventiva y Salud Pública e Historia de la Ciencia, Salud Pública

مصطلحات موضوعية: Critical care, Cross infection, Evaluation study, Medicina Preventiva y Salud Pública

الوصف: Background: Pseudomonas aeruginosa (PA) is the third leading aetiological agent in healthcare-associated infections (HAIs) and the one most frequently found in patients with pneumonia associated with mechanical ventilation. In intensive care units (ICU), its appearance is associated with higher mortality, an increase in the days spent on ventilation, and hospital stay length and costs. Thus, evaluating strategies for preventing these infections is essential for their control. Therefore, our objective was to evaluate the effectiveness of the systematic use of antimicrobial filters in preventing PA infections in critical care units. Methods: This was an open experimental crossover study. A total of 2,156 patients admitted for more than 24 hours in critical care units were included, 1,129 of them in units with filters, and 1,027 in units without filters. The study groups were followed-up for 24 months and HAIs were checked for the presence of PA. Chi-squared test were used to compare the rate of HAIs between groups and we calculated 95% confidence intervals adjusted by Poisson regression for the rate ratio (RR) of the association magnitude. Results: Both groups were homogeneous in terms of intrinsic and extrinsic patient factors. The incidence of PA infections in the units with filters was 5.5 cases/1,000 hospitalized days and 5.4/1,000 hospitalized days for the units without water filters (RR = 1.09 [0.67-1.79]). Conclusions: Routine placing antimicrobial filters in the water taps in critical care units was not an effective means of preventing the emergence of HAIs caused by PA. ; This study has been funded by: Instituto de Salud Carlos III (Carlos III Health Institute) through Fund for Health Research (FIS), Ministry of Health, Spanish Government. Project # PI15/01344; Generalitat Valenciana (Valencian Regional Government) Grants for Support to a Research or Technology Transfer Project. Project # APOTIP/2016/A/011; Alicante Institute for Health and Biomedical Research through Grants to supplement the development ...

العلاقة: https://doi.org/10.1016/j.ajic.2021.10.029Test; info:eu-repo/grantAgreement/ISCIII//PI15%2F01344; American Journal of Infection Control. 2022, 50(4): 435-439. https://doi.org/10.1016/j.ajic.2021.10.029Test; 0196-6553 (Print); 1527-3296 (Online); http://hdl.handle.net/10045/122651Test

الإتاحة: https://doi.org/10.1016/j.ajic.2021.10.029Test
http://hdl.handle.net/10045/122651Test