المؤلفون: Johannes Buchner, Yuji Goto, Cardine N. Nokwe, Jirka Peschek, Bernd Reif, Martin Zacharias, Hisashi Yagi, Manuel Hora

المصدر: J. Mol. Biol. 428, 1315-1332 (2016)

مصطلحات موضوعية: 0301 basic medicine, Amyloid, Mutant, Immunoglobulin domain, Immunoglobulin light chain, Fibril, Protein Aggregation, Pathological, Antibodies, 03 medical and health sciences, Structural Biology, Amyloid precursor protein, medicine, Humans, Immunoglobulin Fold, Antibody Amyloid, Domain Stability, Point Mutations, Protein Folding And Aggregation Disease, Molecular Biology, 030102 biochemistry & molecular biology, biology, Chemistry, Point mutation, Amyloidosis, medicine.disease, 030104 developmental biology, Biochemistry, biology.protein, Biophysics, Mutant Proteins, Protein Multimerization

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6b7d8aaf4c8a891635adda40c54727fTest
https://pubmed.ncbi.nlm.nih.gov/26827727Test

المؤلفون: Gerd Multhaup, Elke Prade, Riddhiman Sarkar, Heiko J. Bittner, Juan Miguel López del Amo, Peter W. Hildebrand, Bernd Reif, Gerhard Althoff-Ospelt

مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Amyloid, Plasma protein binding, macromolecular substances, Fibril, Biochemistry, Protein Structure, Secondary, Protein structure, Sulindac, Alzheimer Disease, mental disorders, medicine, Humans, Molecular Biology, Amyloid beta-Peptides, Chemistry, Anti-Inflammatory Agents, Non-Steroidal, Cell Biology, medicine.disease, Small molecule, Protein Structure and Folding, Biophysics, Salt bridge, Alzheimer's disease, Hydrophobic and Hydrophilic Interactions, medicine.drug, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f147c1d01b26fae101e527677407dc0Test
https://europepmc.org/articles/PMC4661391Test/

المؤلفون: Hartmut Oschkinat, Niels Chr. Nielsen, Bernd Reif, Ümit Akbey, Daxiu Wei, Morten Bjerring, Berit Paaske

المصدر: Wei, D, Akbey, U, Jensen, B P, Oschkinat, H, Reif, B, Bjerring, M & Nielsen, N C 2011, ' Optimal 2H rf pulses and 2H-13C cross-polarization methods for solid-state 2H MAS NMR of perdeuterated proteins ', The Journal of Physical Chemistry Letters, vol. 2, no. 11, pp. 1289-1294 . https://doi.org/10.1021/jz200511bTest

مصطلحات موضوعية: Solid-state nuclear magnetic resonance, Chemistry, Cross polarization, Analytical chemistry, Solid-state, General Materials Science, Physical and Theoretical Chemistry, Atomic physics, Optimal control, Quantum, Order of magnitude, Coherence (physics)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d242b0a7e7edac17df9e4de44cb95d3eTest
https://pubmed.ncbi.nlm.nih.gov/26295423Test

المؤلفون: Bernd Reif, Sam Asami

المصدر: Journal of Biomolecular NMR. 52:31-39

مصطلحات موضوعية: Carbon Isotopes, Proton, Protein Conformation, Chemistry, Fatty Acids, Resolution (electron density), Analytical chemistry, Spectrin, Resonance, Protonation, Nuclear magnetic resonance spectroscopy, Biochemistry, Crystallography, Protein structure, Structural biology, Animals, Molecule, Protons, Chickens, Nuclear Magnetic Resonance, Biomolecular, Spectroscopy

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c24dad8d672f218a3755db3720585482Test
https://doi.org/10.1007/s10858-011-9591-4Test

المؤلفون: Bernd Reif, Paola Turano, Enrico Ravera, Giacomo Parigi, Ivano Bertini, Claudio Luchinat

المصدر: Proceedings of the National Academy of Sciences; Vol 108

مصطلحات موضوعية: Multidisciplinary, 010405 organic chemistry, Chemistry, Precipitation (chemistry), Analytical chemistry, Proteins, 010402 general chemistry, 01 natural sciences, 0104 chemical sciences, law.invention, NMR spectra database, Crystallography, Solid-state nuclear magnetic resonance, law, Phase (matter), Physical Sciences, Magic angle spinning, Molecule, Ultracentrifuge, Crystallization, Nuclear Magnetic Resonance, Biomolecular, Ultracentrifugation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f76704fed07150b0dbd84dbc5f473f7Test

المؤلفون: Juan Miguel López del Amo, Ronald Frank, Bernd Reif, Marcus Fändrich, Björn Grüning, Stefan Günther, Jan Bieschke, Erich E. Wanker, Michael Schmidt, Franziska Schiele, Annett Boeddrich, Thomas Wiglenda, Qinwen Wang, Roger Anwyl, Rudi Lurz, Daniela Kleckers, Sigrid Schnoegl, Dominic M. Walsh, Ralf P. Friedrich, Martin Herbst

المصدر: Nature Chemical Biology; Vol 8
Nature Chemical Biology

مصطلحات موضوعية: Models, Molecular, Amyloid, Beta sheet, 010402 general chemistry, Fibril, Hippocampus, Synaptic Transmission, 01 natural sciences, Protein Structure, Secondary, 03 medical and health sciences, Protein structure, Microscopy, Electron, Transmission, Cell Line, Tumor, Oxazines, Humans, Amino Acid Sequence, Molecular Biology, Peptide sequence, 030304 developmental biology, 0303 health sciences, Chemistry, Fibrillogenesis, Long-term potentiation, Cell Biology, Small molecule, Peptide Fragments, 0104 chemical sciences, Biochemistry, Hydrophobic and Hydrophilic Interactions

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f30fcb247be102ca7b8ff9fa4541a40Test

المؤلفون: Anna Klukovits, Friedrich W. Herberg, Kornelia Hampel, Dmitry Kashin, Kerstin Zühlke, Judit Verli, Andrey C. da Costa Goncalves, Mangesh Joshi, Hannelore Haase, Martin W. Bergmann, Bernd Reif, Marta Dr. Szaszak, Dorothea Lorenz, Robert S. Kass, Dermot M.F. Cooper, Hans G. Genieser, Ingo Morano, Solveig Grossmann, Sabine Friedl, Bastian Zimmermann, Marie C. Moutty, Peter Schmieder, Frank Christian, Hendrikje Göttert, George S. Baillie, Frank Götz, Carolyn Vargas, Walter Rosenthal, Miles D. Houslay, Jens Furkert, Jens Peter von Kries, Róbert Gáspár, Claudia Noack, Stephan Drewianka, Debbie Willoughby, Enno Klussmann

المصدر: The Journal of Biological Chemistry
The journal of biological chemistry, 286: 9079-9096

مصطلحات موضوعية: Male, Allosteric regulation, Cyclic AMP (cAMP), Adenylate Cyclase (Adenylyl Cyclase), AKAP18, A Kinase Anchor Proteins, Biology, Biochemistry, Rats, Inbred WKY, Second Messenger Systems, Protein Phosphorylation, 03 medical and health sciences, Enzyme activator, AKAP150, 0302 clinical medicine, AKAP, Allosteric Regulation, Cyclic AMP, Myocyte, Animals, Protein phosphorylation, Myocytes, Cardiac, Protein kinase A, Molecular Biology, Protein Kinase Inhibitors, 030304 developmental biology, Heart Failure, 0303 health sciences, Protein Kinase A (PKA), Cell Biology, Yotiao, Cyclic AMP-Dependent Protein Kinases, Myocardial Contraction, 3. Good health, Cell biology, Rats, Enzyme Activation, Compartmentalization, Protein-Protein Interactions, Second messenger system, Chronic Disease, Signal Transduction, Compartmentalized Signaling, Signal transduction, 030217 neurology & neurosurgery

وصف الملف: text

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::524465e5c34273c7764a0932ea83b11aTest
http://europepmc.org/articles/PMC3058960Test

المؤلفون: Bernd Reif, Uwe Fink, Juan Miguel López del Amo

المصدر: Journal of Biomolecular NMR. 48:203-212

مصطلحات موضوعية: Protein Conformation, Hydrogen bond, Protein dynamics, Relaxation (NMR), Analytical chemistry, Deuterium Exchange Measurement, Proteins, Spectrin, Hydrogen Bonding, Deuterium, Amides, Biochemistry, src Homology Domains, chemistry.chemical_compound, Solid-state nuclear magnetic resonance, chemistry, Computational chemistry, Amide, Kinetic isotope effect, Hydrogen–deuterium exchange, Nuclear Magnetic Resonance, Biomolecular, Spectroscopy, Hydrogen

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca2241e1d3dbb9ffdcfde31f1502f1f9Test
https://doi.org/10.1007/s10858-010-9450-8Test

المؤلفون: Alexey Krushelnitsky, Tatiana Zinkevich, Detlef Reichert, Veniamin Chevelkov, Bernd Reif

المصدر: Journal of the American Chemical Society. 132:11850-11853

مصطلحات موضوعية: Residue (complex analysis), Magnetic Resonance Spectroscopy, Time Factors, Scale (ratio), Chemistry, Relaxation (NMR), Temperature, Analytical chemistry, Spectrin, Protonation, General Chemistry, Biochemistry, Catalysis, Microsecond, Colloid and Surface Chemistry, Microcrystalline, Animals, Irradiation, Chickens

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29043027b15b819cec9dbefebcf1e39cTest
https://doi.org/10.1021/ja103582nTest

المؤلفون: Muralidhar Dasari, Julia Ness, Sascha Weggen, Bruno Bulic, Gerd Multhaup, Stephanie Unterreitmeier, Lisa-Marie Munter, Ronald Gust, Luise Richter, Peter W. Hildebrand, Bernd Reif, Dieter Langosch, Michael Beyermann

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 107(33): 14597–14602

مصطلحات موضوعية: Models, Molecular, CHO Cells, Plasma protein binding, Amyloid beta-Protein Precursor, Cricetulus, Sulindac, Cricetinae, Amyloid precursor protein, Animals, Humans, Amino Acid Sequence, Peptide sequence, chemistry.chemical_classification, Amyloid beta-Peptides, Multidisciplinary, Molecular Structure, biology, Chemistry, P3 peptide, Surface Plasmon Resonance, Biological Sciences, Peptide Fragments, Transmembrane protein, Amino acid, Ectodomain, Biochemistry, biology.protein, Amyloid Precursor Protein Secretases, Protein Multimerization, Amyloid precursor protein secretase, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba34c6bfcfa929650b3f6e4b1809a369Test
https://doi.org/10.1073/pnas.1003026107Test