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1كتاب
المؤلفون: Beck, James H., Beck, James H.
المصدر: Mennonite Quarterly Review. 75,4 (2001) 407-427
مصطلحات موضوعية: Jews -- Germany, Judaism -- Relations -- Christianity, Christianity and other religions -- Judaism, Jews -- History -- Germany -- 1500-1800, Jews -- Germany -- Worms, Bible. German -- Versions
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2دورية
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3رسالة جامعية
المؤلفون: Beck, James J.W.
مرشدي الرسالة: Wilson, Andrew S., Snaith, Beverly, Hardy, Maryann L.
مصطلحات موضوعية: Radiography, Safeguarding, Child, Abuse, Survey, Interview, Knowledge, Attitude, Practice
الوصف: Background- Diagnostic radiography is an established method of investigating child safeguarding concerns. The role of the radiographer in identifying signs that represent safeguarding concerns and acting as a conduit between the patient and other professionals is less well understood. Aims- To evaluate the role of the radiographer in child safeguarding. Establish the contributory factors that influence that role and identify the measures that can be taken to maximise the contribution that could be made to protect patients. Methods- A multimethod approach of two studies (KAP survey and semi-structured interviews) was implemented sequentially to permit the second study to be influenced by the results of the first. Results - An inconsistent knowledge base in terms of child safeguarding exists. A positive attitude towards the profession’s role was identified and an inference that the profession does contribute to the escalation process, albeit only exceptionally. Conclusion- Those in the earlier stages of their career are most in need of recognising suspicious appearances. Radiographic appearances are commensurate with the modality utilised and needs accounting for within education. Contemporary practice makes assessment of more abstract appearances of child safeguarding concerns challenging. The systems of escalating concerns are known, and the profession is willing and able to contribute. Recommendations- Educational focus on the recognition of pathognomonic signs of abuse and aetiology to permit recognition of occasions when injury and clinical history disagree. Education should also include child safeguarding concerns commensurate with the modality utilised and as part of image reporting. Further research is needed to promote the role of the profession and to evaluate the impact of technological advancement on the profession’s capability to contribute effectively.
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4دورية أكاديمية
المؤلفون: Arsiwala, Lubaina T, Mok, Yejin, Yang, Chao, Ishigami, Junichi, Selvin, Elizabeth, Beck, James D, Allison, Matthew A, Heiss, Gerardo, Demmer, Ryan T, Matsushita, Kunihiro
المصدر: Journal of Periodontology. 93(7)
مصطلحات موضوعية: Cardiovascular, Infectious Diseases, Prevention, Dental/Oral and Craniofacial Disease, Clinical Research, Oral and gastrointestinal, Good Health and Well Being, Atherosclerosis, Humans, Incidence, Periodontal Diseases, Peripheral Arterial Disease, Prospective Studies, Risk Factors, Tooth Loss, cohort studies, periodontal diseases, peripheral arterial disease, tooth loss, Dentistry
الوصف: BackgroundThe association of periodontal disease with atherosclerotic cardiovascular diseases is well known, but not specifically with incident peripheral artery disease (PAD). Therefore, we studied the associations of periodontal disease with incident PAD in a population-based setting.MethodsAmong 9,793 participants (aged 53-75 years) without prevalent PAD, self-reported history of periodontal disease was ascertained. Of these, 5,872 participants underwent full-mouth examinations from which periodontal status was defined using the US Centers for Disease Control and Prevention-American Academy of Periodontology (CDC-AAP) definition. We quantified the association of periodontal disease with incident PAD (defined by hospital admission diagnosis or procedures) using multivariable Cox regression models.ResultsDuring a median follow-up of 20.1 years, 360 participants (3.6%) developed PAD. In models accounting for potential confounders including diabetes and smoking pack-years, there was higher hazard of PAD in participants with self-reported tooth loss because of periodontal disease (hazard ratio:1.54 [95% CI:1.20-1.98]), history of periodontal disease treatment (1.37 [1.05-1.80]), and periodontal disease diagnosis (1.38 [1.09-1.74]), compared to their respective counterparts. The clinical measure of periodontal disease (n = 5,872) was not significantly associated with incident PAD in the fully adjusted model (e.g., 1.53 [0.94-2.50] in CDC-AAP-defined severe periodontal disease versus no disease).ConclusionWe observed a modest association of self-reported periodontal disease, especially when resulting in tooth loss, with incident PAD in the general population. Nonetheless, a larger study with the clinical measure of periodontal disease is warranted.
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/80n0s8hgTest
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5دورية أكاديمية
المساهمون: U.S. Department of Veterans Affairs
المصدر: Journal of Biomedical Materials Research Part B: Applied Biomaterials ; volume 112, issue 3 ; ISSN 1552-4973 1552-4981
الوصف: Patients implanted with osseointegrated (OI) prosthetic systems have reported vastly improved upper and lower extremity prosthetic function compared with their previous experience with socket‐suspension systems. However, OI systems have been associated with superficial and deep‐bone infections and implant loosening due, in part, to a failure of the osseointegration process. Although monitoring the osseointegration using circulating biomarkers has clinical relevance for understanding the progression of osseointegration with these devices, it has yet to be established. Ten patients were enrolled in this study. Blood samples were collected at pre‐selected times, starting before implantation surgery, and continuing to 12 months after the second surgery. Bone formation markers, bone resorption markers, and circulating amino acids were measured from blood samples. A linear mixed model was generated for each marker, incorporating patient ID and age with the normalized marker value as the response variable. Post hoc comparisons were made between 1 week before Stage 1 Surgery and all subsequent time points for each marker, followed by multiple testing corrections. Serial radiographic imaging of the residual limb containing the implant was obtained during follow‐up, and the cortical index (CI) was calculated for the bone at the porous region of the device. Two markers of bone formation, specifically bone‐specific alkaline phosphatase (Bone‐ALP) and amino‐terminal propeptide of type I procollagen (PINP), exhibited significant increases when compared with the baseline levels of unloaded residual bone prior to the initial surgery, and they subsequently returned to their baseline levels by the 12‐month mark. Patients who experienced clinically robust osseointegration experienced increased cortical bone thickness at the porous coated region of the device. A medium correlation was observed between Bone‐ALP and the porous CI values up to PoS2‐M1 ( p = .056), while no correlation was observed for PINP. An increase in ...
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6دورية أكاديمية
المساهمون: U.S. Department of Veterans Affairs
المصدر: Journal of Biomedical Materials Research Part B: Applied Biomaterials ; volume 112, issue 2 ; ISSN 1552-4973 1552-4981
الوصف: Hydroxyapatite (HA)‐based materials are widely used as bone substitutes due to their inherent biocompatibility, osteoconductivity, and bio‐absorption properties. However, HA scaffolds lack compressive strength when compared to autograft bone. It has been shown that the fluoridated form of HA, fluorapatite (FA), can be sintered to obtain this desired strength as well as slower degradation properties. Also, FA surfaces have been previously shown to promote stem cell differentiation toward an osteogenic lineage. Thus, it was hypothesized that FA, with and without stromal vascular fraction (SVF), would guide bone healing to an equal or better extent than the clinical gold standard. The regenerative potentials of these scaffolds were tested in 32 Lewis rats in a femoral condylar defect model with untreated (negative), isograft (positive), and commercial HA as controls. Animals were survived for 12 weeks post‐implantation. A semi‐quantitative micro‐CT analysis was developed to quantify the percent new bone formation within the defects. Our model showed significantly higher ( p < .05) new bone depositions in all apatite groups compared to the autograft group. Overall, the FA group had the most significant new bone deposition, while the differences between HA, FA, and FA + SVF were insignificant ( p > .05). Histological observations supported the micro‐CT findings and highlighted the presence of healthy bone tissues without interposing capsules or intense immune responses for FA groups. Most importantly, the regenerating bone tissue within the FA + SVF scaffolds resembled the architecture of the surrounding trabecular bone, showing intertrabecular spaces, while the FA group presented a denser cortical bone‐like architecture. Also, a lower density of cells was observed near FA granules compared to HA surfaces, suggesting a reduced immune response. This first in vivo rat study supported the tested hypothesis, illustrating the utility of FA as a bone scaffold material.
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7تقرير
المؤلفون: Beck, James L.
مصطلحات موضوعية: Quantum Physics
الوصف: A neo-classical relativistic mechanics theory is presented where the spin of an electron is a natural part of its space-time path as a point particle. The fourth-order equation of motion corresponds to the same Lagrangian function in proper time as in special relativity except for an additional spin energy term. The total motion can be decomposed into a sum of a local spin motion about a point and a global motion of this point, called the spin center. The global motion is sub-luminal and obeys Newton's second law in proper time, the time for a clock fixed at the spin center, while the total motion occurs at the speed of light c, consistent with the eigenvalues of Dirac's velocity operators having magnitude c. The local spin motion corresponds to Schr\"odinger's zitterbewegung and is a perpetual motion, which for a free electron has a circular path in the spin-center frame. In an electro-magnetic field, this spin motion generates magnetic and electric dipole energies through the Lorentz force on the electron's point charge. The corresponding electric dipole energy is consistent with the spin-orbit coupling term in the corrected Pauli non-relativistic Hamiltonian but the magnetic dipole energy is one half of that in Dirac's theory. By defining a spin tensor as the angular momentum of the electron's total motion about its spin center, the fundamental equations of motion can be re-written in an identical form to those of the Barut-Zanghi electron theory. These equations of motion can then be expressed using operators applied to a state function of proper time satisfying a Dirac-Schr\"odinger spinor equation. The operators produce dynamic variables without any probability implications. For the free electron, the state function satisfies Dirac's relativistic wave equation when the Lorentz transformation is applied to express proper time in terms of an observer's space-time coordinates.
Comment: Version 3 is the same as that published in Foundations of Physics in May 2023 except that 2 typos in Eqs. (B.3), (B.4) are corrected. There is an obvious typo in the identity for the Dirac matrices on page 21 of the FOP paper; it is not in the 3 arXiv versions. The paper title was changed slightly in the FOP paper from the first two arXiv versions and Section 6: Concluding Remarks was revisedالوصول الحر: http://arxiv.org/abs/2108.07267Test
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8دورية
المؤلفون: Beck, James C., Maj
المصدر: Marine Corps Gazette. 08/1991 75(8):86-91
مصطلحات موضوعية: KINETIC ENERGY WEAPONS, MARINE CORPS - United States - Equipment, ANTITANK WEAPONS
الوصف: illus
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9دورية أكاديمية
المؤلفون: Tanner, Caroline M, Cummings, Steven R, Schwarzschild, Michael A, Brown, Ethan G, Dorsey, E Ray, Espay, Alberto J, Galifianakis, Nicholas B, Goldman, Samuel M, Litvan, Irene, Luthra, Nijee, McFarland, Nikolaus R, Mitchell, Kyle T, Standaert, David G, Bauer, Douglas C, Greenspan, Susan L, Beck, James C, Lyles, Kenneth W
المصدر: NPJ Parkinson's disease. 7(1)
الوصف: The Trial of Parkinson's And Zoledronic acid (TOPAZ, https://clinicaltrials.gov/ct2/show/NCT03924414Test ) is a unique collaboration between experts in movement disorders and osteoporosis to test the efficacy of zoledronic acid, an FDA-approved parenteral treatment for osteoporosis, for fracture prevention in people with neurodegenerative parkinsonism. Aiming to enroll 3,500 participants age 65 years or older, TOPAZ is one of the largest randomized, placebo-controlled clinical trials ever attempted in parkinsonism. The feasibility of TOPAZ is enhanced by its design as a U.S.- wide home-based trial without geographical limits. Participants receive information from multiple sources, including specialty practices, support groups and websites. Conducting TOPAZ in participants' homes takes advantage of online consent technology, the capacity to confirm diagnosis using telemedicine and the availability of research nursing to provide screening and parenteral therapy in homes. Home-based clinical research may provide an efficient, convenient, less expensive method that opens participation in clinical trials to almost anyone with parkinsonism.
الوصول الحر: https://escholarship.org/uc/item/0ph6d58wTest
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10دورية أكاديمية
المؤلفون: Pei, Jin-Song, Gay-Balmaz, François, Luscher, Darby J, Beck, James L, Todd, Michael D, Wright, Joseph P, Qiao, Yu, Quadrelli, Marco B, Farrar, Chuck R, Lieven, Nicholas AJ
المصدر: Nonlinear Dynamics. 103(2)
مصطلحات موضوعية: Mem-models, Absement, Generalized momentum, Nonlinear state-space representation, Hybrid dynamical system, Continuum damage mechanics, Damage variable, Strain ratcheting, Wiechert model, Classical Preisach model, Mathematical Sciences, Engineering, Acoustics
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/44n2t4jgTest
