المؤلفون: Soest, Robert, Leeuwen, Pim, Boormans, Joost, Bangma VERVALLEN, CH

المصدر: Soest , R , Leeuwen , P , Boormans , J & Bangma VERVALLEN , CH 2018 , ' Abiraterone and androgen-deprivation therapy for hormone-sensitive metastatic prostate cancer: Is the era of androgen deprivation monotherapy over? - Abirateron in combinatie met androgeendeprivatietherapie bij patiënten met hormoonnaïef gemetastaseerd prostaatcarcinoom ' , Tijdschrift voor Urologie , vol. 8 , no. 4 , pp. 60-65 . https://doi.org/10.1007/s13629-017-0196-xTest

مصطلحات موضوعية: /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, SDG 3 - Good Health and Well-being

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1007/s13629-017-0196-xTest
https://pure.eur.nl/en/publications/8a576d68-2867-4d1b-b899-feb1bbbfb7b7Test
https://pure.eur.nl/ws/files/48318138/Repub_128295_O-A.pdfTest

المؤلفون: Venderbos, Lionne, Roobol - Bouts, Monique, Bangma VERVALLEN, CH, Bergh, RCN, Bokhorst, Leonard, Nieboer, Daan, Godtman, R, Hugosson, J, van der Kwast, T, Steyerberg, Ewout

المصدر: Venderbos , L , Roobol - Bouts , M , Bangma VERVALLEN , CH , Bergh , RCN , Bokhorst , L , Nieboer , D , Godtman , R , Hugosson , J , van der Kwast , T & Steyerberg , E 2016 , ' Rule-based versus probabilistic selection for active surveillance using three definitions of insignificant prostate cancer ' , World Journal of Urology , vol. 34 , no. 2 , pp. 253-260 . https://doi.org/10.1007/s00345-015-1628-yTest

مصطلحات موضوعية: /dk/atira/pure/keywords/researchprograms/AFL001000/EMCMM034901, name=EMC MM-03-49-01, /dk/atira/pure/keywords/researchprograms/AFL001000/EMCNIHES026501, name=EMC NIHES-02-65-01, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

الوصف: To study whether probabilistic selection by the use of a nomogram could improve patient selection for active surveillance (AS) compared to the various sets of rule-based AS inclusion criteria currently used. We studied Dutch and Swedish patients participating in the European Randomized study of Screening for Prostate Cancer (ERSPC). We explored which men who were initially diagnosed with cT1-2, Gleason 6 (Gleason pattern a parts per thousand currency sign3 + 3) had histopathological indolent PCa at RP [defined as pT2, Gleason pattern a parts per thousand currency sign3 and tumour volume (TV) a parts per thousand currency sign0.5 or TV a parts per thousand currency sign 1.3 ml, and TV no part of criteria (NoTV)]. Rule-based selection was according to the Prostate cancer Research International: Active Surveillance (PRIAS), Klotz, and Johns Hopkins criteria. An existing nomogram to define probability-based selection for AS was refitted for the TV1.3 and NoTV indolent PCa definitions. 619 of 864 men undergoing RP had cT1-2, Gleason 6 disease at diagnosis and were analysed. Median follow-up was 8.9 years. 229 (37 %), 356 (58 %), and 410 (66 %) fulfilled the TV0.5, TV1.3, and NoTV indolent PCa criteria at RP. Discriminating between indolent and significant disease according to area under the curve (AUC) was: TV0.5: 0.658 (PRIAS), 0.523 (Klotz), 0.642 (Hopkins), 0.685 (nomogram). TV1.3: 0.630 (PRIAS), 0.550 (Klotz), 0.615 (Hopkins), 0.646 (nomogram). NoTV: 0.603 (PRIAS), 0.530 (Klotz), 0.589 (Hopkins), 0.608 (nomogram). The performance of a nomogram, the Johns Hopkins, and PRIAS rule-based criteria are comparable. Because the nomogram allows individual trade-offs, it could be a good alternative to rigid rule-based criteria.

وصف الملف: application/pdf

العلاقة: https://pure.eur.nl/en/publications/ca5dfd61-63cb-4186-abc7-42034a530b3aTest

الإتاحة: https://doi.org/10.1007/s00345-015-1628-yTest
https://pure.eur.nl/en/publications/ca5dfd61-63cb-4186-abc7-42034a530b3aTest
http://hdl.handle.net/1765/80209Test

المؤلفون: Wever, Elisabeth, Heijnsdijk, Eveline, Draisma, Gerrit, Bangma VERVALLEN, CH, Roobol - Bouts, Monique, Schröder, Fritz, de Koning, Harry

المصدر: Wever , E , Heijnsdijk , E , Draisma , G , Bangma VERVALLEN , CH , Roobol - Bouts , M , Schröder , F & de Koning , H 2013 , ' Treatment of local-regional prostate cancer detected by PSA screening: benefits and harms according to prognostic factors ' , British Journal of Cancer , vol. 108 , no. 10 , pp. 1971-1977 . https://doi.org/10.1038/bjc.2013.198Test

مصطلحات موضوعية: /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, SDG 3 - Good Health and Well-being

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1038/bjc.2013.198Test
https://pure.eur.nl/en/publications/693f5c40-94d6-4c17-bec5-d8a56dc9e671Test
https://pure.eur.nl/ws/files/47504189/Repub_56355_O-A.pdfTest
http://hdl.handle.net/1765/56355Test

المؤلفون: de Bekker - Grob, Esther, Bliemer, MCJ, Donkers, Bas, Bot, Marie-louise, Korfage, Ida, Roobol - Bouts, Monique, Bangma VERVALLEN, CH, Steyerberg, Ewout

المصدر: de Bekker - Grob , E , Bliemer , MCJ , Donkers , B , Bot , M , Korfage , I , Roobol - Bouts , M , Bangma VERVALLEN , CH & Steyerberg , E 2013 , ' Patients' and urologists' preferences for prostate cancer treatment: a discrete choice experiment ' , British Journal of Cancer , vol. 109 , no. 3 , pp. 633-640 . https://doi.org/10.1038/bjc.2013.370Test

مصطلحات موضوعية: /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, SDG 3 - Good Health and Well-being

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1038/bjc.2013.370Test
https://pure.eur.nl/en/publications/e9c7e59e-c80a-440f-8afd-e6ab76e652c5Test
https://pure.eur.nl/ws/files/47503589/007757.pdfTest
http://hdl.handle.net/1765/41505Test

المؤلفون: Loef, C, Dits, Natasja, Steyerberg, Ewout, Kranse, M, van Leenders, Arno, Bangma VERVALLEN, CH, Kraaij, Robert

المصدر: Loef , C , Dits , N , Steyerberg , E , Kranse , M , van Leenders , A , Bangma VERVALLEN , CH & Kraaij , R 2012 , ' The additional value of TGF beta 1 and IL-7 to predict the course of prostate cancer progression ' , Cancer Immunology Immunotherapy , vol. 61 , no. 6 , pp. 905-910 . https://doi.org/10.1007/s00262-011-1159-3Test

مصطلحات موضوعية: /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, SDG 3 - Good Health and Well-being

الوصف: Given the fact that prostate cancer incidence will increase in the coming years, new prognostic biomarkers are needed with regard to the biological aggressiveness of the prostate cancer diagnosed. Since cytokines have been associated with the biology of cancer and its prognosis, we determined whether transforming growth factor beta 1 (TGF beta 1), interleukin-7 (IL-7) receptor and IL-7 levels add additional prognostic information with regard to prostate cancer-specific survival. Retrospective survival analysis of forty-four prostate cancer patients, that underwent radical prostatectomy, was performed (1989-2001). Age, Gleason score and pre-treatment PSA levels were collected. IL-7, IL-7 receptor and TGF beta 1 levels in prostate cancer tissue were determined by quantitative real-time RT-PCR and their additional prognostic value analyzed with regard to prostate cancer survival. Hazard ratios and their confidence intervals were estimated, and Akaike's information criterio The predictive ability of a model for prostate cancer survival more than doubled when TGF beta 1 and IL-7 were added to a model containing only the Gleason score and pre-treatment PSA (AIC: 18.1 and AIC: 6.5, respectively). IL-7 and TGF beta 1 are promising markers to indicate those at risk for poor prostate cancer survival. This additional information may be of interest with regard to the biological aggressiveness of the diagnosed prostate cancer, especially for those patients screened for prostate cancer and their considered therapy.

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1007/s00262-011-1159-3Test
https://pure.eur.nl/en/publications/eafdef49-49c1-4a4f-a0fe-71e153e2b44cTest
https://pure.eur.nl/ws/files/47449446/Repub_64191_O-A.pdfTest
http://hdl.handle.net/1765/64191Test

المؤلفون: Wever, Elisabeth, Hugosson, J, Heijnsdijk, Eveline, Bangma VERVALLEN, CH, Draisma, Gerrit, de Koning, Harry

المصدر: Wever , E , Hugosson , J , Heijnsdijk , E , Bangma VERVALLEN , CH , Draisma , G & de Koning , H 2012 , ' To be screened or not to be screened? Modeling the consequences of PSA screening for the individual ' , British Journal of Cancer , vol. 107 , no. 5 , pp. 778-784 . https://doi.org/10.1038/bjc.2012.317Test

مصطلحات موضوعية: /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, SDG 3 - Good Health and Well-being

الوصف: BACKGROUND: Screening with prostate-specific antigen (PSA) can reduce prostate cancer mortality, but may advance diagnosis and treatment in time and lead to overdetection and overtreatment. We estimated benefits and adverse effects of PSA screening for individuals who are deciding whether or not to be screened. METHODS: Using a microsimulation model, we estimated lifetime probabilities of prostate cancer diagnosis and death, overall life expectancy and expected time to diagnosis, both with and without screening. We calculated anticipated loss in quality of life due to prostate cancer diagnosis and treatment that would be acceptable to decide in favour of screening. RESULTS: Men who were screened had a gain in life expectancy of 0.08 years but their expected time to diagnosis decreased by 1.53 life-years. Of the screened men, 0.99% gained on average 8.08 life-years and for 17.43% expected time to diagnosis decreased by 8.78 life-years. These figures imply that the anticipated loss in quality of life owing to diagnosis and treatment should not exceed 4.8%, for screening to have a positive effect on quality-adjusted life expectancy. CONCLUSION: The decision to be screened should depend on personal preferences. The negative impact of screening might be reduced by screening men who are more willing to accept the side effects from treatment. British Journal of Cancer (2012) 107, 778-784. doi:10.1038/bjc.2012.317 www.bjcancer.com Published online 17 July 2012 (C) 2012 Cancer Research UK

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1038/bjc.2012.317Test
https://pure.eur.nl/en/publications/c7ab3184-2175-481d-80a4-8d11125cabf5Test
https://pure.eur.nl/ws/files/47448988/REPUB_61258_OA.pdfTest
http://hdl.handle.net/1765/61258Test

المؤلفون: Schroeder, RPJ, van Weerden, Wytske, Krenning, Eric, Bangma VERVALLEN, CH, Berndsen, Saskia, Ligt, Corine, Groen, Harald, Reneman, Suzanne, de Blois, Erik, Breeman, Wout, Jong, Marion

المصدر: Schroeder , RPJ , van Weerden , W , Krenning , E , Bangma VERVALLEN , CH , Berndsen , S , Ligt , C , Groen , H , Reneman , S , de Blois , E , Breeman , W & Jong , M 2011 , ' Gastrin-releasing peptide receptor-based targeting using bombesin analogues is superior to metabolism-based targeting using choline for in vivo imaging of human prostate cancer xenografts ' , European Journal of Nuclear Medicine and Molecular Imaging , vol. 38 , no. 7 , pp. 1257-1266 . https://doi.org/10.1007/s00259-011-1775-3Test

مصطلحات موضوعية: /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, SDG 3 - Good Health and Well-being

الوصف: Purpose Prostate cancer (PC) is a major health problem. Overexpression of the gastrin-releasing peptide receptor (GRPR) in PC, but not in the hyperplastic prostate, provides a promising target for staging and monitoring of PC. Based on the assumption that cancer cells have increased metabolic activity, metabolism-based tracers are also being used for PC imaging. We compared GRPR-based targeting using the (68)Ga-labelled bombesin analogue AMBA with metabolism-based targeting using (18)F-methylcholine ((18)F-FCH) in nude mice bearing human prostate VCaP xenografts. Methods PET and biodistribution studies were performed with both (68)Ga-AMBA and (18)F-FCH in all VCaP tumour-bearing mice, with PC-3 tumour-bearing mice as reference. Scanning started immediately after injection. Dynamic PET scans were reconstructed and analysed quantitatively. Biodistribution of tracers and tissue uptake was expressed as percent of injected dose per gram tissue (%ID/g). Results All tumours were clearly visualized using (68)Ga-AMBA. (18)F-FCH showed significantly less contrast due to poor tumour-to-background ratios. Quantitative PET analyses showed fast tumour uptake and high retention for both tracers. VCaP tumour uptake values determined from PET at steady-state were 6.7 +/- 1.4%ID/g (20-30 min after injection, N=8) for (68)Ga-AMBA and 1.6 +/- 0.5%ID/g (10-20 min after injection, N=8) for (18)F-FCH, which were significantly different (p<0.001). The results in PC-3 tumour-bearing mice were comparable. Biodistribution data were in accordance with the PET results showing VCaP tumour uptake values of 9.5 +/- 4.8% ID/g (N=8) for (68)Ga-AMBA and 2.1 +/- 0.4% ID/g (N=8) for (18)F-FCH. Apart from the GRPR-expressing organs, uptake in all organs was lower for (68)Ga-AMBA than for (18)F-FCH. Conclusion Tumour uptake of (68)Ga-AMBA was higher while overall background activity was lower than observed for (18)F-FCH in the same PC-bearing mice. These results suggest that peptide receptor-based targeting using the bombesin analogue AMBA is ...

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1007/s00259-011-1775-3Test
https://pure.eur.nl/en/publications/d85ca7af-785f-4a7b-92e2-239331ade9c7Test
https://pure.eur.nl/ws/files/47126700/21431398_OA.pdfTest
http://hdl.handle.net/1765/24025Test

المؤلفون: Blijenberg, BG, Wildhagen, Mark, Bangma VERVALLEN, CH, Finlay, JA, Väisänen, V, Schröder, Fritz

المصدر: Blijenberg , BG , Wildhagen , M , Bangma VERVALLEN , CH , Finlay , JA , Väisänen , V & Schröder , F 2003 , ' Comparison of two assays for human kallikrein 2 ' , Clinical Chemistry , vol. 49 , no. 2 , pp. 243-247 . https://doi.org/10.1373/49.2.243Test

مصطلحات موضوعية: /dk/atira/pure/keywords/researchprograms/AFL001000/EMCMM034901, name=EMC MM-03-49-01

وصف الملف: application/pdf

العلاقة: https://pure.eur.nl/en/publications/db19e10c-ae49-40a4-87a3-4ad57a162801Test

الإتاحة: https://doi.org/10.1373/49.2.243Test
https://pure.eur.nl/en/publications/db19e10c-ae49-40a4-87a3-4ad57a162801Test
https://pure.eur.nl/ws/files/46512656/12560346.pdfTest
http://hdl.handle.net/1765/10086Test

المؤلفون: Kusaka, N, Nasu, Y, Arata, R, Saika, T, Tsushima, T, Kraaij, Robert, Bangma VERVALLEN, CH, Kumon, H

المصدر: Kusaka , N , Nasu , Y , Arata , R , Saika , T , Tsushima , T , Kraaij , R , Bangma VERVALLEN , CH & Kumon , H 2001 , ' Transrectal ultrasound for monitoring murine orthotopic prostate tumor ' , Prostate , vol. 47 , pp. 118-124 . https://doi.org/10.1002/pros.1054Test

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1002/pros.1054Test
https://pure.eur.nl/en/publications/837f2d54-ed05-4849-8a8b-7c3c13140238Test
https://pure.eur.nl/ws/files/46628599/Kusaka_et_al-2001-The_Prostate.pdfTest
http://hdl.handle.net/1765/65408Test

المؤلفون: Heijnsdijk, Eveline, Bangma VERVALLEN, CH, Borras, JM, Carvalho Delgado Marques, Tiago, Castells, X, Eklund, M, Espinas, JA, Graefen, M, Gronberg, H, Lansdorp - Vogelaar, Iris, Leeuwen, Pim, Nelen, V, Recker, F, Roobol - Bouts, Monique, Vandenbulcke, P, de Koning, Harry

المصدر: Heijnsdijk , E , Bangma VERVALLEN , CH , Borras , JM , Carvalho Delgado Marques , T , Castells , X , Eklund , M , Espinas , JA , Graefen , M , Gronberg , H , Lansdorp - Vogelaar , I , Leeuwen , P , Nelen , V , Recker , F , Roobol - Bouts , M , Vandenbulcke , P & de Koning , H 2018 , ' Summary statement on screening for prostate cancer in Europe ' , International Journal of Cancer , vol. 142 , no. 4 , pp. 741-746 . ....

مصطلحات موضوعية: /dk/atira/pure/keywords/researchprograms/AFL001000/EMCMM034901, name=EMC MM-03-49-01, /dk/atira/pure/keywords/researchprograms/AFL001000/EMCNIHES026501, name=EMC NIHES-02-65-01, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

العلاقة: https://pure.eur.nl/en/publications/ffaf62e4-ceca-49b3-b459-ced27307c04bTest

الإتاحة: https://doi.org/10.1002/ijc.31102Test
https://pure.eur.nl/en/publications/ffaf62e4-ceca-49b3-b459-ced27307c04bTest
http://hdl.handle.net/1765/103639Test