المؤلفون: Messier, Stephen P., Callahan, Leigh F., Losina, Elena, Mihalko, Shannon L., Guermazi, Ali, Ip, Edward, Miller, Gary D., Katz, Jeffrey N., Loeser, Richard F., Pietrosimone, Brian G., Soto, Sandra, Cook, James L., Newman, Jovita J., DeVita, Paul, Spindler, Kurt P., Runhaar, Jos, Armitano-Lago, Cortney, Duong, Vicky, Selzer, Faith, Hill, Ryan, Love, Monica, Beavers, Daniel P., Saldana, Santiago, Stoker, Aaron M., Rice, Paige E., Hunter, David J.

المصدر: Messier , S P , Callahan , L F , Losina , E , Mihalko , S L , Guermazi , A , Ip , E , Miller , G D , Katz , J N , Loeser , R F , Pietrosimone , B G , Soto , S , Cook , J L , Newman , J J , DeVita , P , Spindler , K P , Runhaar , J , Armitano-Lago , C , Duong , V , Selzer , F , Hill , R , Love , M , Beavers , D P , ....

مصطلحات موضوعية: /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

الوصف: Background: Osteoarthritis (OA), the leading cause of disability among adults, has no cure and is associated with significant comorbidities. The premise of this randomized clinical trial is that, in a population at risk, a 48-month program of dietary weight loss and exercise will result in less incident structural knee OA compared to control. Methods/design: The Osteoarthritis Prevention Study (TOPS) is a Phase III, assessor-blinded, 48-month, parallel 2 arm, multicenter randomized clinical trial designed to reduce the incidence of structural knee OA. The study objective is to assess the effects of a dietary weight loss, exercise, and weight-loss maintenance program in preventing the development of structural knee OA in females at risk for the disease. TOPS will recruit 1230 ambulatory, community dwelling females with obesity (Body Mass Index (BMI) ≥ 30 kg/m 2 ) and aged ≥50 years with no radiographic (Kellgren-Lawrence grade ≤1) and no magnetic resonance imaging (MRI) evidence of OA in the eligible knee, with no or infrequent knee pain. Incident structural knee OA (defined as tibiofemoral and/or patellofemoral OA on MRI) assessed at 48-months from intervention initiation using the MRI Osteoarthritis Knee Score (MOAKS) is the primary outcome. Secondary outcomes include knee pain, 6-min walk distance, health-related quality of life, knee joint loading during gait, inflammatory biomarkers, and self-efficacy. Cost effectiveness and budgetary impact analyses will determine the value and affordability of this intervention. Discussion: This study will assess the efficacy and cost effectiveness of a dietary weight loss, exercise, and weight-loss maintenance program designed to reduce incident knee OA. Trial registration: ClinicalTrials.gov Identifier: NCT05946044.

وصف الملف: application/pdf

العلاقة: https://pure.eur.nl/en/publications/4f47dedb-a38f-4ef4-8b6f-9146d78ba487Test

الإتاحة: https://doi.org/10.1016/j.ocarto.2023.100418Test
https://pure.eur.nl/en/publications/4f47dedb-a38f-4ef4-8b6f-9146d78ba487Test
https://pure.eur.nl/ws/files/124162103/The_osteoarthritis_prevention_study_TOPS_-_A_randomized_controlled_trial_of_diet_and_exercise_to_prevent_Knee_Osteoarthritis.pdfTest
http://www.scopus.com/inward/record.url?scp=85179044965&partnerID=8YFLogxKTest

المؤلفون: Suedbeck, Jessica R., Russell, Daniel, Armitano‐Lago, Cortney, Ludwig, Emily A.

المصدر: International Journal of Dental Hygiene ; volume 21, issue 4, page 731-737 ; ISSN 1601-5029 1601-5037

الوصف: Objective The objective of this study was to compare the effects of 10 commercially available instrument handle designs' mass and diameter on forearm muscle activity during a simulated periodontal scaling experience. Methods A convenience sample of 25 registered dental hygienists was recruited for this IRB‐approved study. Ten commercially available instruments were categorized into four groups based on their masses and diameters: large diameter/light mass, small diameter/light mass, large diameter/heavy mass and small diameter/heavy mass. Participants were randomized to four instruments, one from each group. Participants scaled with each instrument in a simulated oral environment while muscle activity was collected using surface electromyography. Muscle activity was compared among the four instrument group types. Results Muscle activity of the flexor digitorum superficialis was not significantly influenced by instrument mass ( p = 0.60) or diameter ( p = 0.15). Flexor pollicis longus muscle activity was not significantly influenced by instrument mass ( p = 0.81); diameter had a significant effect ( p = 0.001), with smaller diameter instruments producing more muscle activity. For the extensor digitorum communis and extensor carpi radialis brevis, instrument mass did not significantly affect muscle activity ( p = 0.64, p = 0.43), while diameter narrowly failed to reach significance for both muscles ( p = 0.08, p = 0.08); muscle activity for both muscles increased with smaller diameter instruments. Conclusion Results from this study indicate instrument diameter is more influential than mass on muscle activity generation; small diameter instruments increased muscle activity generation when compared to large diameter instruments. Future research in real‐world settings is needed to determine the clinical impact of these findings.

الإتاحة: https://doi.org/10.1111/idh.12750Test

المؤلفون: Pimentel, Ricky, Armitano-Lago, Cortney, MacPherson, Ryan, Sathyan, Anoop, Twiddy, Jack, Peterson, Kaila, Daniele, Michael, Kiefer, Adam W., Lobaton, Edgar, Pietrosimone, Brian, Franz, Jason R.

المصدر: PLoS Digital Health; 5/14/2024, Vol. 3 Issue 5, p1-15, 15p

المؤلفون: Prebor, Jessica, Samulski, Brittany, Armitano-Lago, Cortney, Morrison, Steven

المصدر: Motor Control; Apr2023, Vol. 27 Issue 2, p258-274, 17p

مصطلحات موضوعية: YOUNG adults, OLD age, AGE differences, WALKING speed, MASTICATION

مستخلص: It is widely accepted that the general process of aging can be reflected by changes in motor function. Typically, optimal performance of a given motor task is observed for healthy young adults with declines being observed for individuals at either end of the lifespan. This study was designed to examine differences in the average and variability (i.e., intraindividual variability) of chewing, simple reaction time, postural control, and walking responses. For this study, 15 healthy children, 15 young adults, and 15 older adults participated. Our results indicated the movement performance for the reaction time and postural sway followed a U shape with young adults having faster reaction times and decreased postural sway compared to the children and older adults. However, this pattern was not preserved across all motor tasks with no age differences emerging for (normalized) gait speed, while chewing rates followed a U-shaped curve with older adults and children chewing at faster rates. Taken together, these findings would indicate that the descriptive changes in motor function with aging are heavily influenced by the nature of the task being performed and are unlikely to follow a singular pattern. [ABSTRACT FROM AUTHOR]

: Copyright of Motor Control is the property of Human Kinetics Publishers, Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Carvajal, Alexander Paz, Esrafilian, Amir, Armitano-Lago, Cortney, Munsch, Amanda, Lisee, Caroline M., Bjornsen, Elizabeth S., Buck, Ashley N., Lalush, David, García, José J., Korhonen, Rami K., Pietrosimone, Brian, Mononen, Mika, Franz, Jason

المصدر: Osteoarthritis and Cartilage ; volume 32, page S263-S264 ; ISSN 1063-4584

مصطلحات موضوعية: Orthopedics and Sports Medicine, Biomedical Engineering, Rheumatology

الإتاحة: https://doi.org/10.1016/j.joca.2024.02.380Test
https://api.elsevier.com/content/article/PII:S1063458424004254?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S1063458424004254?httpAccept=text/plainTest

المؤلفون: Armitano-Lago, Cortney^1,2 (AUTHOR) Cortney_Lago@med.unc.edu, Evans-Pickett, Alyssa¹ (AUTHOR), Davis-Wilson, Hope³ (AUTHOR), Munsch, Amanda⁴ (AUTHOR), Longobardi, Lara² (AUTHOR), Willcockson, Helen² (AUTHOR), Schwartz, Todd A.^5,6 (AUTHOR), Franz, Jason R.⁴ (AUTHOR), Pietrosimone, Brian¹ (AUTHOR)

المصدر: Clinical Rheumatology. Apr2024, Vol. 43 Issue 4, p1363-1373. 11p.

مصطلحات موضوعية: *ANTERIOR cruciate ligament surgery, *EXTRACELLULAR matrix proteins, *GROUND reaction forces (Biomechanics), *CARTILAGE, *GAIT in humans

مستخلص: Purpose: Strong observational evidence has linked changes in limb loading during walking following anterior cruciate ligament reconstruction (ACLR) to posttraumatic osteoarthritis (PTOA). It remains unknown if manipulating peak loading influences joint tissue biochemistry. Thus, the purpose of this study is to determine whether manipulating peak vertical ground reaction force (vGRF) during gait influences changes in serum cartilage oligomeric matrix protein (sCOMP) concentrations in ACLR participants. Methods: Forty ACLR individuals participated in this randomized crossover study (48% female, age = 21.0 ± 4.4 years, BMI = 24.6 ± 3.1). Participants attended four sessions, wherein they completed one of four biofeedback conditions (habitual loading (no biofeedback), high loading (5% increase in vGRF), low loading (5% decrease in vGRF), and symmetrical loading (between-limb symmetry in vGRF)) while walking on a treadmill for 3000 steps. Serum was collected before (baseline), immediately (acute post), 1 h (1 h post), and 3.5 h (3.5 h post) following each condition. A comprehensive general linear mixed model was constructed to address the differences in sCOMP across all conditions and timepoints in all participants and a subgroup of sCOMP Increasers. Results: No sCOMP differences were found across the entire cohort. In the sCOMP Increasers, a significant time × condition interaction was found (F9,206 = 2.6, p = 0.009). sCOMP was lower during high loading than low loading (p = 0.009) acutely (acute post). At 3.5 h post, sCOMP was higher during habitual loading than symmetrical loading (p = 0.001). Conclusion: These data suggest that manipulating lower limb loading in ACLR patients who habitually exhibit an acute increase in sCOMP following walking results in improved biochemical changes linked to cartilage health. Key Points • This study assesses the mechanistic link between lower limb load modification and joint tissue biochemistry at acute and delayed timepoints. • Real-time biofeedback provides a paradigm to experimentally assess the mechanistic link between loading and serum biomarkers. • Manipulating peak loading during gait resulted in a metabolic effect of lower sCOMP concentrations in a subgroup of ACLR individuals. • Peak loading modifications may provide an intervention strategy to mitigate the development of PTOA following ACLR. [ABSTRACT FROM AUTHOR]

المؤلفون: Armitano-Lago, Cortney, Willoughby, Dominic, Kiefer, Adam W.

المصدر: Frontiers in Sports and Active Living ; volume 3 ; ISSN 2624-9367

الوصف: Markerless motion capture systems are promising for the assessment of movement in more real world research and clinical settings. While the technology has come a long way in the last 20 years, it is important for researchers and clinicians to understand the capacities and considerations for implementing these types of systems. The current review provides a SWOT (Strengths, Weaknesses, Opportunities, and Threats) analysis related to the successful adoption of markerless motion capture technology for the assessment of lower-limb musculoskeletal kinematics in sport medicine and performance settings. 31 articles met the a priori inclusion criteria of this analysis. Findings from the analysis indicate that the improving accuracy of these systems via the refinement of machine learning algorithms, combined with their cost efficacy and the enhanced ecological validity outweighs the current weaknesses and threats. Further, the analysis makes clear that there is a need for multidisciplinary collaboration between sport scientists and computer vision scientists to develop accurate clinical and research applications that are specific to sport. While work remains to be done for broad application, markerless motion capture technology is currently on a positive trajectory and the data from this analysis provide an efficient roadmap toward widespread adoption.

الإتاحة: https://doi.org/10.3389/fspor.2021.809898Test

المؤلفون: Suedbeck, Jessica R., Armitano-Lago, Cortney

المصدر: Dental Hygiene Faculty Publications

مصطلحات موضوعية: Instrumentation, Ergonomics, Musculoskeletal disorders, Modified scaling techniques, Dental hygienists, Dental Hygiene, Musculoskeletal Diseases, Occupational Health and Industrial Hygiene

الوصف: Purpose: Dental hygienists perform precision instrumentation tasks repetitively throughout the workday, placing them at increased risk for developing a musculoskeletal disorder. The purpose of this pilot study was to determine differences in muscle activity and pinch force generation between the traditional scaling technique and a modified scaling technique. Methods: A convenience sample of dental hygienists (n=12) acted as their own controls in this counterbalance-designed pilot study. Muscle activity and pinch forces were assessed while participants performed traditional and modified scaling techniques with designated instruments on artificial calculus applied to the lower left quadrant of a typodont, for a period of five minutes. Surface electromyography was used to measure muscle activity; sensors attached to the instrument handle measured pinch forces. Participants were surveyed regarding the instruments used and scaling technique preferences at the conclusion of the session. Parametric and non-parametric tests were used to analyze the data. Descriptive statistics were used to analyze the exit survey. Results: The modified scaling technique required less muscle activity than the traditional technique while scaling, however results were not significant (p >0.05). The traditional scaling technique required greater overall pinch force during scaling (p =.00). Pairwise comparisons revealed significant differences between pinch force generation in the thumb for the two scaling techniques (Z = -2.401, p= 0.016) and in the index finger (Z = -2.223, p= 0.026). The traditional scaling technique generated more pinch force (thumb x = 7.25±4.99, index finger x=2.86±2.14) when compared to the modified scaling technique (thumb x=4.52±2.32, index finger x=1.65±1.28). Participants had a slightly higher preference for the instrument utilized for the modified scaling technique in terms of balance, maneuverability, overall comfort and the associated scaling technique as compared to the instrument utilized for the ...

وصف الملف: application/pdf

العلاقة: https://digitalcommons.odu.edu/dentalhygiene_fac_pubs/53Test; https://digitalcommons.odu.edu/context/dentalhygiene_fac_pubs/article/1053/viewcontent/Suedbeck_2021_TheEffectsoftheTraditionalScalingTechniqueVersusOCR.pdfTest

الإتاحة: https://digitalcommons.odu.edu/dentalhygiene_fac_pubs/53Test
https://digitalcommons.odu.edu/context/dentalhygiene_fac_pubs/article/1053/viewcontent/Suedbeck_2021_TheEffectsoftheTraditionalScalingTechniqueVersusOCR.pdfTest

المؤلفون: Kiefer, Adam W., Armitano-Lago, Cortney, Sathyan, Anoop, Longobardi, Lara, Loeser, Richard, Spang, Jeffrey T., Cohen, Kelly, Pietrosimone, Brian G.

المصدر: Medicine & Science in Sports & Exercise ; volume 53, issue 8S, page 114-114 ; ISSN 1530-0315 0195-9131

الإتاحة: https://doi.org/10.1249/01.mss.0000760460.97900.6eTest

المؤلفون: Armitano-Lago, Cortney, Chaaban, Courtney, Cain, M Spencer, MacPherson, Ryan, Elpers, Jackson R., Padua, Darin, Silva, Paula L., Wikstrom, Erik A., Kiefer, Adam W.

المصدر: Medicine & Science in Sports & Exercise ; volume 53, issue 8S, page 176-176 ; ISSN 1530-0315 0195-9131

الإتاحة: https://doi.org/10.1249/01.mss.0000761116.63791.a0Test