المؤلفون: Baragaña, Beatriz, Forte, Barbara, Choi, Ryan, Nakazawa Hewitt, Stephen, Bueren-Calabuig, Juan A., Pisco, João Pedro, Peet, Caroline, Dranow, David M., Robinson, David A., Jansen, Chimed, Norcross, Neil R., Vinayak, Sumiti, Anderson, Mark, Brooks, Carrie F., Cooper, Caitlin A., Damerow, Sebastian, Delves, Michael, Dowers, Karen, Duffy, James, Edwards, Thomas E., Hallyburton, Irene, Horst, Benjamin G., Hulverson, Matthew A., Ferguson, Liam, Jiménez-Díaz, María Belén, Jumani, Rajiv S., Lorimer, Donald D., Love, Melissa S., Maher, Steven, Matthews, Holly, McNamara, Case W., Miller, Peter, O'Neill, Sandra, Ojo, Kayode K., Osuna-Cabello, Maria, Pinto, Erika, Post, John, Riley, Jennifer, Rottmann, Matthias, Sanz, Laura M., Scullion, Paul, Sharma, Arvind, Shepherd, Sharon M., Shishikura, Yoko, Simeons, Frederick R. C., Stebbins, Erin E., Stojanovski, Laste, Straschil, Ursula, Tamaki, Fabio K., Tamjar, Jevgenia, Torrie, Leah S., Vantaux, Amélie, Witkowski, Benoît, Wittlin, Sergio, Yogavel, Manickam, Zuccotto, Fabio, Angulo-Barturen, Iñigo, Sinden, Robert, Baum, Jake, Gamo, Francisco-Javier, Mäser, Pascal, Kyle, Dennis E., Winzeler, Elizabeth A., Myler, Peter J., Wyatt, Paul G., Floyd, David, Matthews, David, Sharma, Amit, Striepen, Boris, Huston, Christopher D., Gray, David W., Fairlamb, Alan H., Pisliakov, Andrei V., Walpole, Chris, Read, Kevin D., Van Voorhis, Wesley C., Gilbert, Ian H.

وصف الملف: application/pdf

العلاقة: https://edoc.unibas.ch/70292/1/20190423161725_5cbf1e75d8ae9.pdfTest; Baragaña, Beatriz and Forte, Barbara and Choi, Ryan and Nakazawa Hewitt, Stephen and Bueren-Calabuig, Juan A. and Pisco, João Pedro and Peet, Caroline and Dranow, David M. and Robinson, David A. and Jansen, Chimed and Norcross, Neil R. and Vinayak, Sumiti and Anderson, Mark and Brooks, Carrie F. and Cooper, Caitlin A. and Damerow, Sebastian and Delves, Michael and Dowers, Karen and Duffy, James and Edwards, Thomas E. and Hallyburton, Irene and Horst, Benjamin G. and Hulverson, Matthew A. and Ferguson, Liam and Jiménez-Díaz, María Belén and Jumani, Rajiv S. and Lorimer, Donald D. and Love, Melissa S. and Maher, Steven and Matthews, Holly and McNamara, Case W. and Miller, Peter and O'Neill, Sandra and Ojo, Kayode K. and Osuna-Cabello, Maria and Pinto, Erika and Post, John and Riley, Jennifer and Rottmann, Matthias and Sanz, Laura M. and Scullion, Paul and Sharma, Arvind and Shepherd, Sharon M. and Shishikura, Yoko and Simeons, Frederick R. C. and Stebbins, Erin E. and Stojanovski, Laste and Straschil, Ursula and Tamaki, Fabio K. and Tamjar, Jevgenia and Torrie, Leah S. and Vantaux, Amélie and Witkowski, Benoît and Wittlin, Sergio and Yogavel, Manickam and Zuccotto, Fabio and Angulo-Barturen, Iñigo and Sinden, Robert and Baum, Jake and Gamo, Francisco-Javier and Mäser, Pascal and Kyle, Dennis E. and Winzeler, Elizabeth A. and Myler, Peter J. and Wyatt, Paul G. and Floyd, David and Matthews, David and Sharma, Amit and Striepen, Boris and Huston, Christopher D. and Gray, David W. and Fairlamb, Alan H. and Pisliakov, Andrei V. and Walpole, Chris and Read, Kevin D. and Van Voorhis, Wesley C. and Gilbert, Ian H. (2019) Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis. Proceedings of the National Academy of Sciences of the United States of America, 116 (14). pp. 7015-7020.; info:pmid/30894487; urn:ISSN:0027-8424

الإتاحة: https://doi.org/10.1073/pnas.1814685116Test
https://edoc.unibas.ch/70292Test/
https://edoc.unibas.ch/70292/1/20190423161725_5cbf1e75d8ae9.pdfTest

المؤلفون: Kovada, Vadims, Withers-Martinez, Chrislaine, Bobrovs, Raitis, Ce̅rule, Hele̅na, Liepins, Edgars, Grinberga, Solveiga, Hackett, Fiona, Collins, Christine R., Kreicberga, Agrita, Jiménez-Díaz, María Belén, Angulo-Barturen, Iñigo, Rasina, Dace, Suna, Edgars, Jaudzems, Kristaps, Blackman, Michael J., Jirgensons, Aigars

المصدر: Journal of Medicinal Chemistry; August 2023, Vol. 66 Issue: 15 p10658-10680, 23p

المؤلفون: Gumbo, Tawanda, Angulo-Barturen, Iñigo, Ferrer-Bazaga, Santiago

المصدر: The Journal of Infectious Diseases, 2015 Jun . 211, S96-S106.

الوصول الحر: http://www.jstor.org/stable/43708413Test

المؤلفون: Brunschwig, Christel, Lawrence, Nina, Taylor, Dale, Abay, Efrem, Njoroge, Mathew, Basarab, Gregory S., Le Manach, Claire, Paquet, Tanya, Cabrera, Diego Gonzàlez, Nchinda, Aloysius T., de Kock, Carmen, Wiesner, Lubbe, Denti, Paolo, Waterson, David, Blasco, Benjamin, Leroy, Didier, Witty, Michael J., Donini, Cristina, Duffy, James, Wittlin, Sergio, White, Karen L., Charman, Susan A., Jiménez-Díaz, Maria Belén, Angulo-Barturen, Iñigo, Herreros, Esperanza, Gamo, Francisco Javier, Rochford, Rosemary, Mancama, Dalu, Coetzer, Theresa L., van der Watt, Mariëtte E., Reader, Janette, Birkholtz, Lyn-Marie, Marsh, Kennan C., Solapure, Suresh M., Burke, John E., McPhail, Jacob A., Vanaerschot, Manu, Fidock, David A., Fish, Paul V., Siegl, Peter, Smith, Dennis A., Wirjanata, Grennady, Noviyanti, Rintis, Price, Ric N., Marfurt, Jutta, Silue, Kigbafori D., Street, Leslie J., Chibale, Kelly

وصف الملف: application/pdf

العلاقة: https://edoc.unibas.ch/65596/1/20180925140908_5baa2564af088.pdfTest; Brunschwig, Christel and Lawrence, Nina and Taylor, Dale and Abay, Efrem and Njoroge, Mathew and Basarab, Gregory S. and Le Manach, Claire and Paquet, Tanya and Cabrera, Diego Gonzàlez and Nchinda, Aloysius T. and de Kock, Carmen and Wiesner, Lubbe and Denti, Paolo and Waterson, David and Blasco, Benjamin and Leroy, Didier and Witty, Michael J. and Donini, Cristina and Duffy, James and Wittlin, Sergio and White, Karen L. and Charman, Susan A. and Jiménez-Díaz, Maria Belén and Angulo-Barturen, Iñigo and Herreros, Esperanza and Gamo, Francisco Javier and Rochford, Rosemary and Mancama, Dalu and Coetzer, Theresa L. and van der Watt, Mariëtte E. and Reader, Janette and Birkholtz, Lyn-Marie and Marsh, Kennan C. and Solapure, Suresh M. and Burke, John E. and McPhail, Jacob A. and Vanaerschot, Manu and Fidock, David A. and Fish, Paul V. and Siegl, Peter and Smith, Dennis A. and Wirjanata, Grennady and Noviyanti, Rintis and Price, Ric N. and Marfurt, Jutta and Silue, Kigbafori D. and Street, Leslie J. and Chibale, Kelly. (2018) UCT943, a next generation Plasmodium falciparum PI4K inhibitor preclinical candidate for the treatment of malaria. Antimicrobial agents and chemotherapy, 62 (9). e00012-e00018.; info:pmid/29941635; urn:ISSN:0066-4804; urn:ISSN:1098-6596

الإتاحة: https://doi.org/10.1128/AAC.00012-18Test
https://edoc.unibas.ch/65596Test/
https://edoc.unibas.ch/65596/1/20180925140908_5baa2564af088.pdfTest

المؤلفون: Brunschwig, Christel, Lawrence, Nina, Taylor, Dale, Abay, Efrem, Njoroge, Mathew, Basarab, Gregory S., Le Manach, Claire, Paquet, Tanya, Gonzàlez Cabrera, Diego, Nchinda, Aloysius T., de Kock, Carmen, Wiesner, Lubbe, Denti, Paolo, Waterson, David, Blasco, Benjamin, Leroy, Didier, Witty, Michael J., Donini, Cristina, Duffy, James, Wittlin, Sergio, White, Karen L., Charman, Susan A., Jiménez-Díaz, Maria Belén, Angulo-Barturen, Iñigo, Herreros, Esperanza, Gamo, Francisco Javier, Rochford, Rosemary, Mancama, Dalu, Coetzer, Theresa L., van der Watt, Mariëtte E., Reader, Janette, Birkholtz, Lyn Marie, Marsh, Kennan C., Solapure, Suresh M., Burke, John E., McPhail, Jacob A., Vanaerschot, Manu, Fidock, David A., Fish, Paul V., Siegl, Peter, Smith, Dennis A., Wirjanata, Grennady, Noviyanti, Rintis, Price, Ric N., Marfurt, Jutta, Silue, Kigbafori D., Street, Leslie J., Chibale, Kelly

المصدر: Brunschwig , C , Lawrence , N , Taylor , D , Abay , E , Njoroge , M , Basarab , G S , Le Manach , C , Paquet , T , Gonzàlez Cabrera , D , Nchinda , A T , de Kock , C , Wiesner , L , Denti , P , Waterson , D , Blasco , B , Leroy , D , Witty , M J , Donini , C , Duffy , J , Wittlin , S , White , K L , Charman , S A , Jiménez-Díaz , M ....

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1128/AAC.01941-18Test
https://research.monash.edu/en/publications/c4cfbdd3-c380-4c7e-9135-7d95505f3051Test
https://researchmgt.monash.edu/ws/files/258389869/256602798_oa.pdfTest
http://www.scopus.com/inward/record.url?scp=85055602859&partnerID=8YFLogxKTest

المؤلفون: O' Neill, Paul M, Stocks, Paul A, Sabbani, Sunil, Roberts, Natalie L, Amewu, Richard K, Shore, Emma R, Aljayyoussi, Ghaith, Angulo-Barturén, Iñigo, Belén, María, Díaz, Jiménez, Bazaga, Santiago Ferrer, Martínez, María Santos, Campo, Brice, Sharma, Raman, Charman, Susan A, Ryan, Eileen, Chen, Gong, Shackleford, David M, Davies, Jill, Nixon, Gemma L, Biagini, Giancarlo, Ward, Steve

المصدر: Bioorganic and Medicinal Chemistry, Vol 26, Issue 11, pp. 2996-3005.

مصطلحات موضوعية: WA 110 Prevention and control of communicable diseases. Transmission of infectious diseases, WC 750 Malaria, WC 770 Therapy

وصف الملف: text

العلاقة: https://archive.lstmed.ac.uk/8684/1/synthesis%20and%20profiling%20of%20benzylmorpholine.docxTest; O' Neill, Paul M, Stocks, Paul A, Sabbani, Sunil, Roberts, Natalie L, Amewu, Richard K, Shore, Emma R, Aljayyoussi, Ghaith, Angulo-Barturén, Iñigo, Belén, María, Díaz, Jiménez, Bazaga, Santiago Ferrer, Martínez, María Santos, Campo, Brice, Sharma, Raman, Charman, Susan A, Ryan, Eileen, Chen, Gong, Shackleford, David M, Davies, Jill, Nixon, Gemma L, Biagini, Giancarlo orcid:0000-0001-6356-6595 and Ward, Steve orcid:0000-0003-2331-3192 (2018) 'Synthesis and profiling of benzylmorpholine 1,2,4,5-tetraoxane analogue N205: Towards tetraoxane scaffolds with potential for single dose cure of malaria.'. Bioorganic and Medicinal Chemistry, Vol 26, Issue 11, pp. 2996-3005.

الإتاحة: https://archive.lstmed.ac.uk/8684Test/
https://www.sciencedirect.com/science/article/pii/S0968089618302037Test
https://archive.lstmed.ac.uk/8684/1/synthesis%20and%20profiling%20of%20benzylmorpholine.docxTest

المؤلفون: Mendes, António M., Machado, Marta, Gonçalves-Rosa, Nataniel, Reuling, Isaie J., Foquet, Lander, Marques, Cláudia, Salman, Ahmed M., Yang, Annie S. P., Moser, Kara A., Dwivedi, Ankit, Hermsen, Cornelus C., Jiménez-Díaz, Belén, Viera, Sara, Santos, Jorge M., Albuquerque, Inês, Bhatia, Sangeeta N., Bial, John, Angulo-Barturen, Iñigo, Silva, Joana C., Leroux-Roels, Geert, Janse, Chris J., Khan, Shahid M., Mota, Maria M., Sauerwein, Robert W., Prudêncio, Miguel

المصدر: npj Vaccines ; volume 3, issue 1 ; ISSN 2059-0105

مصطلحات موضوعية: Pharmacology (medical), Infectious Diseases, Pharmacology, Immunology

الإتاحة: https://doi.org/10.1038/s41541-018-0068-2Test
https://www.nature.com/articles/s41541-018-0068-2.pdfTest
https://www.nature.com/articles/s41541-018-0068-2Test

المؤلفون: Paquet, Tanya, Le Manach, Claire, Cabrera, Diego González, Younis, Yassir, Henrich, Philipp P., Abraham, Tara S., Lee, Marcus C.S., Basak, Rajshekhar, Ghidelli-Disse, Sonja, Lafuente-Monasterio, María José, Bantscheff, Marcus, Ruecker, Andrea, Blagborough, Andrew M., Zakutansky, Sara E., Zeeman, Anne Marie, White, Karen L., Shackleford, David M., Mannila, Janne, Morizzi, Julia, Scheurer, Christian, Angulo-Barturen, Iñigo, Santosmartínez, María, Ferrer, Santiago, Sanz, Laura María, Gamo, Francisco Javier, Reader, Janette, Botha, Mariette, Dechering, Koen J., Sauerwein, Robert W., Tungtaeng, Anchalee, Vanachayangkul, Pattaraporn, Lim, Chek Shik, Burrows, Jeremy, Witty, Michael J., Marsh, Kennan C., Bodenreider, Christophe, Rochford, Rosemary, Solapure, Suresh M., Jiménez-Díaz, María Belén, Wittlin, Sergio, Charman, Susan A., Donini, Cristina, Campo, Brice, Birkholtz, Lyn Marie, Khanson, Kirsten, Drewes, Gerard, Kocken, Clemensh M., Delves, Michael J., Leroy, Didier, Fidock, David A., Waterson, David, Street, Leslie J., Chibale, Kelly

المصدر: Paquet , T , Le Manach , C , Cabrera , D G , Younis , Y , Henrich , P P , Abraham , T S , Lee , M C S , Basak , R , Ghidelli-Disse , S , Lafuente-Monasterio , M J , Bantscheff , M , Ruecker , A , Blagborough , A M , Zakutansky , S E , Zeeman , A M , White , K L , Shackleford , D M , Mannila , J , Morizzi , J , Scheurer , C , Angulo-Barturen , I , Santosmartínez , M ....

مصطلحات موضوعية: /dk/atira/pure/subjectarea/asjc/2700/2700, name=General Medicine

العلاقة: https://discovery.dundee.ac.uk/en/publications/f96e07b3-664b-4f71-be9a-e8c29fb1c1d6Test

الإتاحة: https://doi.org/10.1126/scitranslmed.aad9735Test
https://discovery.dundee.ac.uk/en/publications/f96e07b3-664b-4f71-be9a-e8c29fb1c1d6Test
http://www.scopus.com/inward/record.url?scp=85018309975&partnerID=8YFLogxKTest

المؤلفون: O'Neill, Paul M, Amewu, Richard K, Charman, Susan A, Sabbani, Sunil, Gnädig, Nina F, Straimer, Judith, Fidock, David A, Shore, Emma R, Roberts, Natalie L, Wong, Michael H-L, Hong, W David, Pidathala, Chandrakala, Riley, Chris, Murphy, Ben, Aljayyoussi, Ghaith, Gamo, Francisco Javier, Sanz, Laura, Rodrigues, Janneth, Cortes, Carolina Gonzalez, Herreros, Esperanza, Angulo-Barturén, Iñigo, Jiménez-Díaz, María Belén, Bazaga, Santiago Ferrer, Martínez-Martínez, María Santos, Campo, Brice, Sharma, Raman, Ryan, Eileen, Shackleford, David M, Campbell, Simon, Smith, Dennis A, Wirjanata, Grennady, Noviyanti, Rintis, Price, Ric N, Marfurt, Jutta, Palmer, Michael J, Copple, Ian M, Mercer, Amy E, Ruecker, Andrea, Delves, Michael J, Sinden, Robert E, Siegl, Peter, Davies, Jill, Rochford, Rosemary, Kocken, Clemens H M, Zeeman, Anne-Marie, Nixon, Gemma L, Biagini, Giancarlo, Ward, Steve

المصدر: Nature Communications, Vol 8, e15159.

مصطلحات موضوعية: QV 256 Antimalarials, QV 38 Drug action, QX 20 Research (General), QX 600 Insect control. Tick control, WC 750 Malaria, WC 765 Prevention and control

وصف الملف: text

العلاقة: https://archive.lstmed.ac.uk/7196/1/Nature_Comm_8_15159_2017.pdfTest; O'Neill, Paul M, Amewu, Richard K, Charman, Susan A, Sabbani, Sunil, Gnädig, Nina F, Straimer, Judith, Fidock, David A, Shore, Emma R, Roberts, Natalie L, Wong, Michael H-L, Hong, W David, Pidathala, Chandrakala, Riley, Chris, Murphy, Ben, Aljayyoussi, Ghaith, Gamo, Francisco Javier, Sanz, Laura, Rodrigues, Janneth, Cortes, Carolina Gonzalez, Herreros, Esperanza, Angulo-Barturén, Iñigo, Jiménez-Díaz, María Belén, Bazaga, Santiago Ferrer, Martínez-Martínez, María Santos, Campo, Brice, Sharma, Raman, Ryan, Eileen, Shackleford, David M, Campbell, Simon, Smith, Dennis A, Wirjanata, Grennady, Noviyanti, Rintis, Price, Ric N, Marfurt, Jutta, Palmer, Michael J, Copple, Ian M, Mercer, Amy E, Ruecker, Andrea, Delves, Michael J, Sinden, Robert E, Siegl, Peter, Davies, Jill, Rochford, Rosemary, Kocken, Clemens H M, Zeeman, Anne-Marie, Nixon, Gemma L, Biagini, Giancarlo orcid:0000-0001-6356-6595 and Ward, Steve orcid:0000-0003-2331-3192 (2017) 'A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance.'. Nature Communications, Vol 8, e15159.

الإتاحة: https://archive.lstmed.ac.uk/7196Test/
http://www.nature.com/articles/ncomms15159Test
https://archive.lstmed.ac.uk/7196/1/Nature_Comm_8_15159_2017.pdfTest

المؤلفون: Baker, David A, Stewart, Lindsay B, Large, Jonathan M, Bowyer, Paul W, Ansell, Keith H, Jiménez-Díaz, María B, El Bakkouri, Majida, Birchall, Kristian, Dechering, Koen J, Bouloc, Nathalie S, Coombs, Peter J, Whalley, David, Harding, Denise J, Smiljanic-Hurley, Ela, Wheldon, Mary C, Walker, Eloise M, Dessens, Johannes T, Lafuente, María José, Sanz, Laura M, Gamo, Francisco-Javier, Ferrer, Santiago B, Hui, Raymond, Bousema, Teun, Angulo-Barturén, Iñigo, Merritt, Andy T, Croft, Simon L, Gutteridge, Winston E, Kettleborough, Catherine A, Osborne, Simon A

وصف الملف: text

العلاقة: https://researchonline.lshtm.ac.uk/id/eprint/4349230/1/s41467-017-00572-x.pdfTest; https://researchonline.lshtm.ac.uk/id/eprint/4349230/1/malarial%20cGMP-dependent%20protein%20kinase_GREEN%20AAM.pdfTest; Baker, David A ; Stewart, Lindsay B ; Large, Jonathan M; Bowyer, Paul W; Ansell, Keith H; Jiménez-Díaz, María B; El Bakkouri, Majida; Birchall, Kristian; Dechering, Koen J; Bouloc, Nathalie S; +19 more. Coombs, Peter J; Whalley, David; Harding, Denise J; Smiljanic-Hurley, Ela; Wheldon, Mary C; Walker, Eloise M ; Dessens, Johannes T ; Lafuente, María José; Sanz, Laura M; Gamo, Francisco-Javier; Ferrer, Santiago B; Hui, Raymond; Bousema, Teun; Angulo-Barturén, Iñigo; Merritt, Andy T; Croft, Simon L ; Gutteridge, Winston E; Kettleborough, Catherine A; Osborne, Simon A; (2017) A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission. Nature communications, 8 (1). 430-. ISSN 2041-1723 DOI: https://doi.org/10.1038/s41467-017-00572-xTest

الإتاحة: https://doi.org/10.1038/s41467-017-00572-xTest
https://researchonline.lshtm.ac.uk/id/eprint/4349230Test/
https://researchonline.lshtm.ac.uk/id/eprint/4349230/1/s41467-017-00572-x.pdfTest
https://researchonline.lshtm.ac.uk/id/eprint/4349230/1/malarial%20cGMP-dependent%20protein%20kinase_GREEN%20AAM.pdfTest