المؤلفون: Albena T. Dinkova-Kostova, Holly Robertson, Stephen T. Durant, Steven Vitale, John D. Hayes, Trevor M. Penning, Lauren E. Tebay

المصدر: Free Radical Biology and Medicine. 88:108-146

مصطلحات موضوعية: biology, Carcinogenesis, NF-E2-Related Factor 2, mTORC1, Biochemistry, mTORC2, KEAP1, Article, Ubiquitin ligase, Oxidative Stress, Physiology (medical), Ubiquitin ligase complex, biology.protein, Animals, Humans, Thioredoxin, Signal transduction, Oxidation-Reduction, Protein kinase B, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ce00a9db0f2c22e1554dec0e59e96e0Test
https://doi.org/10.1016/j.freeradbiomed.2015.06.021Test

المؤلفون: Geoff Wells, Hélène Bertrand, Albena T. Dinkova-Kostova, Clarisse Thiollier, Nikolaos D. Georgakopoulos, Adrian Fowkes, Liam Baird, Hiroko Kachi, Marjolein Schaap

المصدر: Journal of Medicinal Chemistry. 58:7186-7194

مصطلحات موضوعية: NF-E2-Related Factor 2, Fluorescence Polarization, digestive system, environment and public health, Protein–protein interaction, Structure-Activity Relationship, Isothiocyanates, Cell Line, Tumor, Drug Discovery, NAD(P)H Dehydrogenase (Quinone), Humans, Computer Simulation, Gene, Transcription factor, Kelch-Like ECH-Associated Protein 1, Dose-Response Relationship, Drug, Chemistry, Intracellular Signaling Peptides and Proteins, Triazoles, respiratory system, KEAP1, Keap1 nrf2, In vitro, Molecular Docking Simulation, HEK293 Cells, Biochemistry, Design synthesis, Sulfoxides, Triazole derivatives, Molecular Medicine, Click Chemistry, Databases, Chemical, Heme Oxygenase-1, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f76d1b3dbeb42db193152b017b60d3aTest
https://doi.org/10.1021/acs.jmedchem.5b00602Test

المؤلفون: Colin J. Meyer, Kira M. Holmström, Liam Baird, Albena T. Dinkova-Kostova, Andrey Y. Abramov

المصدر: Biochemical Society Transactions

مصطلحات موضوعية: Models, Molecular, NF-E2-Related Factor 2, Oxidative phosphorylation, Mitochondrion, Biology, S2, digestive system, environment and public health, Biochemistry, The Keap1/Nrf2 Pathway in Health and Disease, S4, 03 medical and health sciences, 0302 clinical medicine, cytoprotection, Animals, Humans, Transcription factor, 030304 developmental biology, 0303 health sciences, Kelch-Like ECH-Associated Protein 1, PINK1, Intracellular Signaling Peptides and Proteins, respiratory system, KEAP1, Mitochondria, Cell biology, FRET/FLIM, Mitochondrial biogenesis, redox, Ubiquitin ligase complex, Signal transduction, Energy Metabolism, Oxidation-Reduction, Biochemical Society Focused Meetings, 030217 neurology & neurosurgery, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f3f5fc8528ebc20c9df441b71249dc5Test
https://doi.org/10.1042/bst20150003Test

المؤلفون: Evanna L. Mills, Dylan G. Ryan, Deepthi Menon, Michael P. Murphy, Anne F. McGettrick, Richard C. Hartley, Elena V. Knatko, Edward T. Chouchani, Marah C. Runtsch, Paul J. Meakin, Mark M. Hughes, Maureen Higgins, Richard G. Carroll, Lee M. Booty, Dina Dikovskaya, Padraic G. Fallon, Daniel C. Sévin, Mark P. Jedrychowski, Christian Frezza, Gino Brunori, Joanna F. McGouran, Roman Fischer, Michael L.J. Ashford, Emily Hams, Louise K. Modis, Martin S. King, Hiran A. Prag, John Szpyt, Stuart T. Caldwell, Edmund R.S. Kunji, Benedikt M. Kessler, Ana S. H. Costa, Albena T. Dinkova-Kostova, Zbigniew Zaslona, Luke A. J. O'Neill

المساهمون: Prag, Hiran [0000-0002-4753-8567], King, Martin [0000-0001-6030-5154], Kunji, Edmund [0000-0002-0610-4500], Frezza, Christian [0000-0002-3293-7397], Murphy, Mike [0000-0003-1115-9618], Apollo - University of Cambridge Repository

المصدر: Nature. 556(7699)

مصطلحات موضوعية: Lipopolysaccharides, 0301 basic medicine, Alkylation, Carboxy-Lyases, NF-E2-Related Factor 2, Metabolite, Anti-Inflammatory Agents, Article, Mice, 03 medical and health sciences, chemistry.chemical_compound, Animals, Humans, Cysteine, Rats, Wistar, Transcription factor, Hydro-Lyases, Cysteine metabolism, Feedback, Physiological, Inflammation, Kelch-Like ECH-Associated Protein 1, Multidisciplinary, Macrophages, Proteins, Succinates, Interferon-beta, KEAP1, Rats, HEK293 Cells, 030104 developmental biology, chemistry, Biochemistry, Cytokines, Aconitate decarboxylase, Cattle, Female, lipids (amino acids, peptides, and proteins)

وصف الملف: application/pdf; application/msword

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9a845963587a3e1de2e622af776d8afTest
http://ora.ox.ac.uk/objects/uuidTest:

المؤلفون: John Hardy, Martine Vercelletto, Noemí Esteras, Albena T. Dinkova-Kostova, Isabelle Le Ber, Eva Carro, Fernando Bartolome, Ángeles Martín-Requero, Tadashi Honda, Andrey Y. Abramov, Claire Boutoleau-Bretonnière, Audrey Gabelle

المساهمون: Bartolomé Robledo, Fernando [0000-0001-9322-8933], Esteras, Noemí [0000-0002-7938-6131], Martín-Requero, Ángeles [0000-0002-3416-9440], Boutoleau-Bretonnière, Claire [0000-0001-9051-6315], Ber, Isabelle Le [0000-0002-2508-5181], Honda, Tadashi [0000-0003-0746-9453], Dinkova-Kostova, Albena T. [0000-0003-0316-9859], Hardy, John A. [0000-0002-3122-0423], Bartolomé Robledo, Fernando, Esteras, Noemí, Martín-Requero, Ángeles, Boutoleau-Bretonnière, Claire, Ber, Isabelle Le, Honda, Tadashi, Dinkova-Kostova, Albena T., Hardy, John A.

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname
Scientific Reports, Vol 8, Iss 1, Pp 1-2 (2018)
Scientific Reports
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid

مصطلحات موضوعية: Male, NF-E2-Related Factor 2, Cell Respiration, Energy metabolism, lcsh:Medicine, Computational biology, Biology, Electron Transport, Pentose Phosphate Pathway, Sequestosome-1 Protein, Homeostasis, Humans, Author Correction, lcsh:Science, Aged, 80 and over, Membrane Potential, Mitochondrial, Multidisciplinary, Published Erratum, lcsh:R, Middle Aged, NAD, Mitochondria, Phenotype, Mutation, Flavin-Adenine Dinucleotide, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, Female, lcsh:Q, Energy Metabolism, Reactive Oxygen Species

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52e6472d9702083933ed2895327020e6Test
http://hdl.handle.net/10261/188885Test

المؤلفون: John D. Hayes, Albena T. Dinkova-Kostova

المصدر: Cancer cell. 32(5)

مصطلحات موضوعية: 0301 basic medicine, Genetics, Cancer Research, Kelch-Like ECH-Associated Protein 1, Oncogene, NF-E2-Related Factor 2, Stress signaling, Drug Resistance, Signal transducing adaptor protein, Cell Biology, Biology, KEAP1, Ubiquitin ligase, Cell biology, 03 medical and health sciences, 030104 developmental biology, Oncology, Neoplasms, Cancer cell, biology.protein, Humans, Gene, Adaptor Proteins, Signal Transducing

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ef48c39e6257f18a27ee33f2fabf5fcTest
https://pubmed.ncbi.nlm.nih.gov/29033244Test

المؤلفون: Albena T. Dinkova-Kostova, John D. Hayes

المصدر: Molecular cell. 68(1)

مصطلحات موضوعية: 0301 basic medicine, Epigenomics, NF-E2-Related Factor 2, Cell, Regulator, Biology, environment and public health, Antioxidants, law.invention, 03 medical and health sciences, 0302 clinical medicine, law, medicine, Humans, Epigenetics, Molecular Biology, Mechanism (biology), Cell Biology, respiratory system, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Acetylation, Cancer cell, Suppressor, Oxidation-Reduction, Protein Processing, Post-Translational, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6872d90ba1b81ed213056a29ab8ce5a8Test
https://pubmed.ncbi.nlm.nih.gov/28985511Test

المؤلفون: Michael Batie, Alena Shmakova, Tom Owen-Hughes, Albena T. Dinkova-Kostova, Ramasubramanian Sundaramoorthy, Daniel Bandarra, Elena V. Knatko, Ivan Muñoz, John Biddlestone, Sonia Rocha

مصطلحات موضوعية: 0303 health sciences, Messenger RNA, Angiogenesis, Colorectal cancer, Cancer, Biology, Bioinformatics, medicine.disease, 3. Good health, Chromatin, 03 medical and health sciences, 0302 clinical medicine, 030220 oncology & carcinogenesis, Cancer cell, Gene expression, medicine, Cancer research, SIN3A, 030304 developmental biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62d055da54cbbf85bc4dacac35d6a53bTest
https://doi.org/10.1101/176032Test

المؤلفون: Ali Gorji, Albena T Dinkova Kostova, Stjepana Kovac, Nico Melzer, Sven G. Meuth, Alexander M. Herrmann

المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 18, Iss 9, p 1935 (2017)

مصطلحات موضوعية: 0301 basic medicine, Review, Pharmacology, Mitochondrion, medicine.disease_cause, Endoplasmic Reticulum, Epileptogenesis, lcsh:Chemistry, Epilepsy, 0302 clinical medicine, Adenosine Triphosphate, Calcium dynamics, Homeostasis, lcsh:QH301-705.5, Spectroscopy, chemistry.chemical_classification, reactive oxygen species, Cell Death, Acquired epilepsy, General Medicine, Computer Science Applications, Mitochondria, NF-E2-Related Factor 2, Biology, Catalysis, Nrf2, Inorganic Chemistry, 03 medical and health sciences, Seizures, medicine, Animals, Humans, Physical and Theoretical Chemistry, Molecular Biology, Reactive oxygen species, calcium, Research, Organic Chemistry, Cell Membrane, medicine.disease, Oxidative Stress, 030104 developmental biology, lcsh:Biology (General), lcsh:QD1-999, chemistry, Calcium Channels, Energy Metabolism, Neuroscience, 030217 neurology & neurosurgery, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b99ddf0d7d6afa74ce83f70daa6f9dTest
https://pubmed.ncbi.nlm.nih.gov/28885567Test

المؤلفون: James Ferguson, Paul Talalay, Ying Zhang, Jed W. Fahey, Albena T. Dinkova-Kostova, Sukirti Kalra, Akira Saito, Suqing Zheng, Maureen Higgins, Elena V. Knatko, Charlotte M. Proby, Robert S. Dawe, Sally H. Ibbotson, Jeffrey T.-J. Huang, Rosemary G. Clarke, Andrea L. Benedict, Tadashi Honda

المصدر: Cancer Prevention Research. 8:475-486

مصطلحات موضوعية: Cancer Research, Skin erythema, Neoplasms, Radiation-Induced, Skin Neoplasms, NF-E2-Related Factor 2, Ultraviolet Rays, Blotting, Western, Biology, Real-Time Polymerase Chain Reaction, medicine.disease_cause, environment and public health, Article, Mice, Downregulation and upregulation, Solar Energy, medicine, Animals, Humans, RNA, Messenger, Carcinogen, Skin, Mice, Knockout, Mice, Hairless, Reverse Transcriptase Polymerase Chain Reaction, Activator (genetics), Interleukin, respiratory system, Healthy Volunteers, Hairless, Mice, Inbred C57BL, Oxidative Stress, Oncology, Immunology, Cancer research, Female, Carcinogenesis, Biomarkers, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d612ec6c81346da85ab140b7f521e02Test
https://doi.org/10.1158/1940-6207.capr-14-0362Test