المؤلفون: Beck, Jürgen, Fung, Christian, Strbian, Daniel, Bütikofer, Lukas, Z'Graggen, Werner J., Lang, Matthias F., Beyeler, Seraina, Gralla, Jan, Ringel, Florian, Schaller, Karl, Plesnila, Nikolaus, Arnold, Marcel, Hacke, Werner, Jüni, Peter, Mendelow, Alexander David, Stapf, Christian, Al-Shahi Salman, Rustam, Bressan, Jenny, Lerch, Stefanie, Hakim, Arsany, Martinez-Majander, Nicolas, Piippo-Karjalainen, Anna, Vajkoczy, Peter, Wolf, Stefan, Schubert, Gerrit A., Höllig, Anke, Veldeman, Michael, Roelz, Roland, Gruber, Andreas, Rauch, Philip, Mielke, Dorothee, Rohde, Veit, Kerz, Thomas, Uhl, Eberhard, Thanasi, Enea, Huttner, Hagen B., Kallmünzer, Bernd, Jaap Kappelle, L., Deinsberger, Wolfgang, Roth, Christian, Lemmens, Robin, Leppert, Jan, Sanmillan, Jose L., Coutinho, Jonathan M., Hackenberg, Katharina A. M., Reimann, Gernot, Mazighi, Mikael, Bassetti, Claudio L. A., Mattle, Heinrich P, Raabe, Andreas, Fischer, Urs, Andereggen, Lukas, Beseoglu, Kerim, Cereda, Carlo, Coluccia, Daniel, Desfontaines, Philippe, Alonso de Leciñana, Maria, Freyschlag, Christian, Gaberel, Thomas, Gerlach, Rüdiger, Gessler, Florian, Güresir, Erdem, Muñoz, Fernando, Jabbarli, Ramazan, Minnerup, Jens, Moniche, Francisco, Peeters, Andre, Pfeilschifter, Waltraud, Tatlisumak, Turgut, Weiland, Judith, Woitzik, Johannes, Wostrack, Maria, Vandertop, W. P.

مصطلحات موضوعية: ddc:610

الوصف: Background It is unknown whether decompressive craniectomy improves clinical outcome for people with spontaneous severe deep intracerebral haemorrhage. The SWITCH trial aimed to assess whether decompressive craniectomy plus best medical treatment in these patients improves outcome at 6 months compared to best medical treatment alone. Methods In this multicentre, randomised, open-label, assessor-blinded trial conducted in 42 stroke centres in Austria, Belgium, Finland, France, Germany, the Netherlands, Spain, Sweden, and Switzerland, adults (18–75 years) with a severe intracerebral haemorrhage involving the basal ganglia or thalamus were randomly assigned to receive either decompressive craniectomy plus best medical treatment or best medical treatment alone. The primary outcome was a score of 5–6 on the modified Rankin Scale (mRS) at 180 days, analysed in the intention-to-treat population. This trial is registered with ClincalTrials.gov , NCT02258919 , and is completed. Findings SWITCH had to be stopped early due to lack of funding. Between Oct 6, 2014, and April 4, 2023, 201 individuals were randomly assigned and 197 gave delayed informed consent (96 decompressive craniectomy plus best medical treatment, 101 best medical treatment). 63 (32%) were women and 134 (68%) men, the median age was 61 years (IQR 51–68), and the median haematoma volume 57 mL (IQR 44–74). 42 (44%) of 95 participants assigned to decompressive craniectomy plus best medical treatment and 55 (58%) assigned to best medical treatment alone had an mRS of 5–6 at 180 days (adjusted risk ratio [aRR] 0·77, 95% CI 0·59 to 1·01, adjusted risk difference [aRD] −13%, 95% CI −26 to 0, p=0·057). In the per-protocol analysis, 36 (47%) of 77 participants in the decompressive craniectomy plus best medical treatment group and 44 (60%) of 73 in the best medical treatment alone group had an mRS of 5–6 (aRR 0·76, 95% CI 0·58 to 1·00, aRD −15%, 95% CI −28 to 0). Severe adverse events occurred in 42 (41%) of 103 participants receiving decompressive craniectomy plus ...

وصف الملف: application/pdf

العلاقة: https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/113598Test; urn:nbn:de:bvb:384-opus4-1135988; https://nbn-resolving.org/urn:nbn:de:bvb:384-opus4-1135988Test; https://doi.org/10.1016/s0140-6736Test(24)00702-5; https://opus.bibliothek.uni-augsburg.de/opus4/files/113598/113598.pdfTest

الإتاحة: https://doi.org/10.1016/s0140-6736Test(24)00702-5
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/113598Test
https://nbn-resolving.org/urn:nbn:de:bvb:384-opus4-1135988Test
https://opus.bibliothek.uni-augsburg.de/opus4/files/113598/113598.pdfTest

المؤلفون: Best, Jonathan G., Ambler, Gareth, Wilson, Duncan, Du, Houwei, Lee, Keon Joo, Lim, Jae Sung, Teo, Kay Cheong, Mak, Henry, Kim, Young Dae, Song, Tae Jin, Selcuk Demirelli, Derya, Nishihara, Masashi, Yoshikawa, Masaaki, Kubacka, Marta, Zietz, Annaelle, Al-Shahi Salman, Rustam, Jäger, Hans Rolf, Lip, Gregory Y.H., Panos, Leonidas, Goeldlin, Martina B., Slater, Lee Anne, Karayiannis, Christopher Charles, Phan, Thanh G., Bellut, Maximilian, Abrigo, Jill, Cheng, Cyrus, Leung, Thomas W., Chu, Winnie, Chappell, Francesca, Makin, Stephen D.J., Van Dam-Nolen, Dianne H.K., Kooi, M. Eline, Köhler, Sebastian, Staals, Julie, Kuchcinski, Grégory, Bordet, Régis, Dubost, Florian, Wardlaw, Joanna M., Soo, Yannie O.Y., Fluri, Felix, Srikanth, Velandai K., Jung, Simon, Peters, Nils, Hara, Hideo, Yakushiji, Yusuke, Necioglu Orken, Dilek, Heo, Ji Hoe, Lau, Gary Kui Kai, Bae, Hee Joon, Werring, David J.

المصدر: Best , J G , Ambler , G , Wilson , D , Du , H , Lee , K J , Lim , J S , Teo , K C , Mak , H , Kim , Y D , Song , T J , Selcuk Demirelli , D , Nishihara , M , Yoshikawa , M , Kubacka , M , Zietz , A , Al-Shahi Salman , R , Jäger , H R , Lip , G Y H , Panos , L , Goeldlin , M B , Slater , L A , Karayiannis , ....

الوصف: Background and Objectives: Visible perivascular spaces are an MRI marker of cerebral small vessel disease and might predict future stroke. However, results from existing studies vary. We aimed to clarify this through a large collaborative multicenter analysis. Methods: We pooled individual patient data from a consortium of prospective cohort studies. Participants had recent ischemic stroke or transient ischemic attack (TIA), underwent baseline MRI, and were followed up for ischemic stroke and symptomatic intracranial hemorrhage (ICH). Perivascular spaces in the basal ganglia (BGPVS) and perivascular spaces in the centrum semiovale (CSOPVS) were rated locally using a validated visual scale. We investigated clinical and radiologic associations cross-sectionally using multinomial logistic regression and prospective associations with ischemic stroke and ICH using Cox regression. Results: We included 7,778 participants (mean age 70.6 years; 42.7% female) from 16 studies, followed up for a median of 1.44 years. Eighty ICH and 424 ischemic strokes occurred. BGPVS were associated with increasing age, hypertension, previous ischemic stroke, previous ICH, lacunes, cerebral microbleeds, and white matter hyperintensities. CSOPVS showed consistently weaker associations. Prospectively, after adjusting for potential confounders including cerebral microbleeds, increasing BGPVS burden was independently associated with future ischemic stroke (versus 0-10 BGPVS, 11-20 BGPVS: HR 1.19, 95% CI 0.93-1.53; 21+ BGPVS: HR 1.50, 95% CI 1.10-2.06; p = 0.040). Higher BGPVS burden was associated with increased ICH risk in univariable analysis, but not in adjusted analyses. CSOPVS were not significantly associated with either outcome. Discussion: In patients with ischemic stroke or TIA, increasing BGPVS burden is associated with more severe cerebral small vessel disease and higher ischemic stroke risk. Neither BGPVS nor CSOPVS were independently associated with future ICH.

وصف الملف: application/pdf

العلاقة: https://pure.eur.nl/en/publications/2272539e-1c34-4178-ab63-cb70623fb4a1Test

الإتاحة: https://doi.org/10.1212/WNL.0000000000207795Test
https://pure.eur.nl/en/publications/2272539e-1c34-4178-ab63-cb70623fb4a1Test
https://pure.eur.nl/ws/files/125690533/WNL.0000000000207795.pdfTest
http://www.scopus.com/inward/record.url?scp=85181546591&partnerID=8YFLogxKTest

المؤلفون: Wang, Xia, Yang, Jie, Moullaali, Tom J, Sandset, Else Charlotte, Woodhouse, Lisa J, Law, Zhe Kang, Arima, Hisatomi, Butcher, Kenneth S, Delcourt, Candice, Edwards, Leon, Gupta, Salil, Jiang, Wen, Koch, Sebastian, Potter, John, Qureshi, Adnan I, Robinson, Thompson G, Al-Shahi Salman, Rustam, Saver, Jeffrey L, Sprigg, Nikola, Wardlaw, Joanna, Anderson, Craig S, Sakamoto, Yuki, Bath, Philip M, Chalmers, John

مصطلحات موضوعية: Adults, blood pressure, cerebral hemorrhage, hematoma, stroke

الوصف: OBJECTIVE: To investigate whether an earlier time to achieving and maintaining systolic blood pressure (SBP) at 120 to 140 mmHg is associated with favorable outcomes in a cohort of patients with acute intracerebral hemorrhage. METHODS: We pooled individual patient data from randomized controlled trials registered in the Blood Pressure in Acute Stroke Collaboration. Time was defined as time form symptom onset plus the time (hour) to first achieve and subsequently maintain SBP at 120 to 140 mmHg over 24 hours. The primary outcome was functional status measured by the modified Rankin Scale at 90 to 180 days. A generalized linear mixed models was used, with adjustment for covariables and trial as a random effect. RESULTS: A total of 5761 patients (mean age, 64.0 [SD, 13.0], 2120 [36.8%] females) were included in analyses. Earlier SBP control was associated with better functional outcomes (modified Rankin Scale score, 3-6; odds ratio, 0.98 [95% CI, 0.97-0.99]) and a significant lower risk of hematoma expansion (0.98, 0.96-1.00). This association was stronger in patients with bigger baseline hematoma volume (>10 mL) compared with those with baseline hematoma volume ≤10 mL (0.006 for interaction). Earlier SBP control was not associated with cardiac or renal adverse events. CONCLUSIONS: Our study confirms a clear time relation between early versus later SBP control (120-140 mmHg) and outcomes in the one-third of patients with intracerebral hemorrhage who attained sustained SBP levels within this range. These data provide further support for the value of early recognition, rapid transport, and prompt initiation of treatment of patients with intracerebral hemorrhage.

العلاقة: https://nottingham-repository.worktribe.com/output/29836719Test; Stroke; Volume 55; Issue 4; Pagination 849-855; https://nottingham-repository.worktribe.com/file/29836719/1/BASC%20ICH%20Time%20To%20Target%20%20BP%20%20Clean%2018122023Test

الإتاحة: https://doi.org/10.1161/STROKEAHA.123.044358Test
https://nottingham-repository.worktribe.com/file/29836719/1/BASC%20ICH%20Time%20To%20Target%20%20BP%20%20Clean%2018122023Test
https://nottingham-repository.worktribe.com/output/29836719Test

المؤلفون: Senff, Jasper R, Singh, Sanjula D, Pasi, Marco, Jolink, Wilmar M T, Rodrigues, Mark A, Schreuder, Floris H B M, Staals, Julie, Schreuder, Tobien, Douwes, Jules P J, Talsma, Jelmer, McKaig, Brenna N, Kourkoulis, Christina, Yechoor, Nirupama, Anderson, Christopher D, Puy, Laurent, Cordonnier, Charlotte, Wermer, Marieke J H, Rothwell, Peter M, Rosand, Jonathan, Klijn, Catharina J M, Al-Shahi Salman, Rustam, Rinkel, Gabriël J E, Viswanathan, Anand, Goldstein, Joshua N, Brouwers, H Bart

المصدر: Senff , J R , Singh , S D , Pasi , M , Jolink , W M T , Rodrigues , M A , Schreuder , F H B M , Staals , J , Schreuder , T , Douwes , J P J , Talsma , J , McKaig , B N , Kourkoulis , C , Yechoor , N , Anderson , C D , Puy , L , Cordonnier , C , Wermer , M J H , Rothwell , P M , Rosand , J , Klijn , C J M , Al-Shahi Salman ....

مصطلحات موضوعية: cerebellum, cohort studies, hemorrhagic stroke, recurrence, stroke, survival

الوصف: BACKGROUND: Spontaneous intracerebral hemorrhage (ICH) in the cerebellum has a poor short-term prognosis, whereas data on the long-term case fatality and recurrent vascular events are sparse. Herewith, we aimed to assess the long-term case fatality and recurrence rate of vascular events after a first cerebellar ICH. METHODS: In this international cohort study, we included patients from 10 hospitals (the United States and Europe from 1997 to 2017) aged =18 years with a first spontaneous cerebellar ICH who were discharged alive. Data on long-term case fatality and recurrence of vascular events (recurrent ICH [supratentoria or infratentorial], ischemic stroke, myocardial infarction, or major vascular surgery) were collected for survival analysis and absolute event rate calculation. RESULTS: We included 405 patients with cerebellar ICH (mean age [SD], 72 [13] years, 49% female). The median survival time was 67 months (interquartile range, 23-100 months), with a cumulative survival rate of 34% at 10-year follow-up (median follow-up time per center ranged: 15-80 months). In the 347 patients with data on vascular events 92 events occurred in 78 patients, after initial cerebellar ICH: 31 (8.9%) patients had a recurrent ICH (absolute event rate, 1.8 per 100 patient-years [95% CI, 1.2-2.6]), 39 (11%) had an ischemic stroke (absolute event rate, 2.3 [95% CI, 1.6-3.2]), 13 (3.7%) had a myocardial infarction (absolute event rate, 0.8 [95% CI, 0.4-1.3]), and 5 (1.4%) underwent major vascular surgery (absolute event rate, 0.3 [95% CI, 0.1-0.7]). The median time to a first vascular event during follow-up was 27 months (interquartile range, 8.7-50 months), with a cumulative hazard of 47% at 10 years. CONCLUSIONS: The long-term prognosis of patients who survive a first spontaneous cerebellar ICH is poor and comparable to that of patients who survive a first supratentorial ICH. Further identification of patients at high risk of vascular events following the initial cerebellar ICH is needed. Including patients with cerebellar ICH ...

العلاقة: https://cris.maastrichtuniversity.nl/en/publications/7c9dc676-a68d-4d58-be65-9ec7a7be4e7cTest

الإتاحة: https://doi.org/10.1161/STROKEAHA.123.044622Test
https://cris.maastrichtuniversity.nl/en/publications/7c9dc676-a68d-4d58-be65-9ec7a7be4e7cTest

المؤلفون: Steinmetz, Jaimie, Seeher, Katrin Maria, Schiess, Nicoline, Nichols, Emma, Cao, Bochen, Servili, Chiara, Cavallera, Vanessa, Cousin, Ewerton, Hagins, Hailey, Moberg, Madeline, Mehlman, Max, Abate, Yohannes Habtegiorgis, Abbas, Jaffar, Abbasi, Madineh Akram, Abbasian, Mohammadreza, Abbastabar, Hedayat, Abdelmasseh, Michael, Abdollahi, Mohammad, Abdollahi, Mozhan, Abdollahifar, Mohammad-Amin, Abd-Rabu, Rami, Abdulah, Deldar Morad, Abdullahi, Auwal, Abedi, Aidin, Abedi, Vida, Abeldaño Zuñiga, Roberto Ariel, Abidi, Hassan, Abiodun, Olumide, Aboagye, Richard Gyan, Abolhassani, Hassan, Aboyans, Victor, Abrha, Woldu Aberhe, Abualhasan, Ahmed, Abu-Gharbieh, Eman, Aburuz, Salahdein, Adamu, Lawan Hassan, Addo, Isaac Yeboah, Adebayo, Oladimeji, Adekanmbi, Victor, Adekiya, Tayo Alex, Adikusuma, Wirawan, Adnani, Qorinah Estiningtyas Sakilah, Adra, Saryia, Afework, Tsion, Afolabi, Aanuoluwapo Adeyimika, Afraz, Ali, Afzal, Saira, Aghamiri, Shahin, Agodi, Antonella, Agyemang-Duah, Williams, Ahinkorah, Bright Opoku, Ahmad, Aqeel, Ahmad, Danish, Ahmad, Sajjad, Ahmadzade, Amir Mahmoud, Ahmed, Ali, Ahmed, Ayman, Ahmed, Haroon, Ahmed, Jivan Qasim, Ahmed, Luai, Ahmed, Muktar Beshir, Ahmed, Syed Anees, Ajami, Marjan, Aji, Budi, Ajumobi, Olufemi, Akade, Seyed Esma'Il, Akbari, Morteza, Akbarialiabad, Hossein, Akhlaghi, Shiva, Akinosoglou, Karolina, Akinyemi, Rufus Olusola, Akonde, Maxwell, Al Hasan, Syed Mahfuz, Alahdab, Fares, Al-Ahdal, Tareq Mohammed Ali, Al-Amer, Rasmieh Mustafa, Albashtawy, Mohammed, Albataineh, Mohammad, Aldawsari, Khalifah, Alemi, Hediyeh, Alemi, Sharifullah, Algammal, Abdelazeem, Al-Gheethi, Adel Ali Saeed, Alhalaiqa, Fadwa Alhalaiqa Naji, Alhassan, Robert Kaba, Ali, Abid, Ali, Endale Alemayehu, Ali, Liaqat, Ali, Mohammed Usman, Ali, Musa Mohammed, Ali, Rafat, Ali, Shahid, Ali, Syed Shujait Shujait, Ali, Zahid, Alif, Sheikh Mohammad, Alimohamadi, Yousef, Aliyi, Ahmednur Adem, Aljofan, Mohamad, Aljunid, Syed Mohamed, Alladi, Suvarna, Almazan, Joseph Uy, Almustanyir, Sami, Al-Omari, Basem, Alqahtani, Jaber, Alqasmi, Ibrahim, Alqutaibi, Ahmed Yaseen, Al-Shahi Salman, Rustam, Altaany, Zaid, Al-Tawfiq, Jaffar, Altirkawi, Khalid, Alvis-Guzman, Nelson, Al-Worafi, Yaser Mohammed, Aly, Hany, Aly, Safwat, Alzoubi, Karem, Amani, Reza, Amindarolzarbi, Alireza, Amiri, Sohrab, Amirzade-Iranaq, Mohammad Hosein, Amu, Hubert, Amugsi, Dickson, Amusa, Ganiyu Adeniyi, Amzat, Jimoh, Ancuceanu, Robert, Anderlini, Deanna, Anderson, David, Andrei, Catalina Liliana, Androudi, Sofia, Angappan, Dhanalakshmi, Angesom, Teklit, Anil, Abhishek, Ansari-Moghaddam, Alireza, Anwer, Razique, Arafat, Mosab, Aravkin, Aleksandr, Areda, Demelash, Ariffin, Hany, Arifin, Hidayat, Arkew, Mesay, Ärnlöv, Johan, Arooj, Mahwish, Artamonov, Anton, Artanti, Kurnia Dwi, Aruleba, Raphael Taiwo, Asadi-Pooya, Ali, Asena, Tilahun Ferede, Asghari-Jafarabadi, Mohammad, Ashraf, Muhammad, Ashraf, Tahira, Atalell, Kendalem Asmare, Athari, Seyyed Shamsadin, Atinafu, Bantalem Tilaye Tilaye, Atorkey, Prince, Atout, Maha Moh'D Wahbi, Atreya, Alok, Aujayeb, Avinash, Avan, Abolfazl, Ayala Quintanilla, Beatriz Paulina, Ayatollahi, Haleh, Ayinde, Olatunde, Ayyoubzadeh, Seyed Mohammad, Azadnajafabad, Sina, Azizi, Zahra, Azizian, Khalil, Azzam, Ahmed, Babaei, Mahsa, Badar, Muhammad, Badiye, Ashish, Baghdadi, Soroush, Bagherieh, Sara, Bai, Ruhai, Baig, Atif Amin, Balakrishnan, Senthilkumar, Balalla, Shivanthi, Baltatu, Ovidiu Constantin, Banach, Maciej, Bandyopadhyay, Soham, Banerjee, Indrajit, Baran, Mehmet Firat, Barboza, Miguel, Barchitta, Martina, Bardhan, Mainak, Barker-Collo, Suzanne Lyn, Bärnighausen, Till Winfried, Barrow, Amadou, Bashash, Davood, Bashiri, Hamideh, Bashiru, Hameed Akande, Basiru, Afisu, Basso, João Diogo, Basu, Sanjay, Batiha, Abdul-Monim Mohammad, Batra, Kavita, Baune, Bernhard, Bedi, Neeraj, Begde, Ahmet, Begum, Tahmina, Behnam, Babak, Behnoush, Amir Hossein, Beiranvand, Maryam, Béjot, Yannick, Bekele, Alehegn, Belete, Melaku Ashagrie, Belgaumi, Uzma Iqbal, Bemanalizadeh, Maryam, Bender, Rose, Benfor, Bright, Bennett, Derrick, Bensenor, Isabela, Berice, Betyna, Bettencourt, Paulo, Beyene, Kebede, Bhadra, Abhishek, Bhagat, Devidas, Bhangdia, Kayleigh, Bhardwaj, Nikha, Bhardwaj, Pankaj, Bhargava, Ashish, Bhaskar, Sonu, Bhat, Ajay Nagesh, Bhat, Vivek, Bhatti, Gurjit Kaur, Bhatti, Jasvinder Singh, Bhatti, Rajbir, Bijani, Ali, Bikbov, Boris, Bilalaga, Mariah Malak, Biswas, Atanu, Bitaraf, Saeid, Bitra, Veera, Bjørge, Tone, Bodolica, Virginia, Bodunrin, Aadam Olalekan, Boloor, Archith, Braithwaite, Dejana, Brayne, Carol, Brenner, Hermann, Briko, Andrey, Bringas Vega, Maria, Brown, Julie, Budke, Christine, Buonsenso, Danilo, Burkart, Katrin, Burns, Richard, Bustanji, Yasser, Butt, Muhammad Hammad, Butt, Nadeem Shafique, Butt, Zahid, Cabral, Lucas Scotta, Caetano dos Santos, Florentino Luciano, Calina, Daniela, Campos-Nonato, Ismael, Cao, Chao, Carabin, Hélène, Cárdenas, Rosario, Carreras, Giulia, Carvalho, Andre, Castañeda-Orjuela, Carlos, Casulli, Adriano, Catalá-López, Ferrán, Catapano, Alberico, Caye, Arthur, Cegolon, Luca, Cenderadewi, Muthia, Cerin, Ester, Chacón-Uscamaita, Pamela, Chan, Jeffrey Shi Kai, Chanie, Gashaw Sisay, Charan, Jaykaran, Chattu, Vijay Kumar, Chekol Abebe, Endeshaw, Chen, Hui, Chen, Jianqi, Chi, Gerald, Chichagi, Fatemeh, Chidambaram, Saravana Babu, Chimoriya, Ritesh, Ching, Patrick, Chitheer, Abdulaal, Chong, Yuen Yu, Chopra, Hitesh, Choudhari, Sonali Gajanan, Chowdhury, Enayet Karim, Chowdhury, Rajiv, Christensen, Hanne, Chu, Dinh-Toi, Chukwu, Isaac Sunday, Chung, Eric, Coberly, Kaleb, Columbus, Alyssa, Comachio, Josielli, Conde, Joao, Cortesi, Paolo Angelo, Costa, Vera Marisa, Couto, Rosa, Criqui, Michael, Cruz-Martins, Natália, Dabbagh Ohadi, Mohammad Amin, Dadana, Sriharsha, Dadras, Omid, Dai, Xiaochen, Dai, Zhaoli, d'Amico, Emanuele, Danawi, Hadi, Dandona, Lalit, Dandona, Rakhi, Darwish, Amira Hamed, Das, Saswati, Das, Subasish, Dascalu, Ana Maria, Dash, Nihar Ranjan, Dashti, Mohsen, de la Hoz, Fernando Pio, de la Torre-Luque, Alejandro, de Leo, Diego, Dean, Frances, Dehghan, Amin, Dehghan, Azizallah, Dejene, Hiwot, Demant, Daniel, Demetriades, Andreas, Demissie, Solomon, Deng, Xinlei, Desai, Hardik Dineshbhai, Devanbu, Vinoth Gnana Chellaiyan, Dhama, Kuldeep, Dharmaratne, Samath Dhamminda, Dhimal, Meghnath, Dias da Silva, Diana, Diaz, Daniel, Dibas, Mahmoud, Ding, Delaney, Dinu, Monica, Dirac, M Ashworth, Diress, Mengistie, Do, Thanh Chi, Do, Thao Huynh Phuong, Doan, Khanh Duy Khanh, Dodangeh, Milad, Doheim, Mohamed Fahmy, Dokova, Klara Georgieva, Dongarwar, Deepa, Dsouza, Haneil Larson, Dube, John, Duraisamy, Senbagam, Durojaiye, Oyewole Christopher, Dutta, Sulagna, Dziedzic, Arkadiusz Marian, Edinur, Hisham Atan, Eissazade, Negin, Ekholuenetale, Michael, Ekundayo, Temitope Cyrus, El Nahas, Nevine, El Sayed, Iman, Elahi Najafi, Mohammad Amin, Elbarazi, Iffat, Elemam, Noha Mousaad, Elgar, Frank, Elgendy, Islam, Elhabashy, Hala Rashad, Elhadi, Muhammed, Elilo, Legesse Tesfaye, Ellenbogen, Richard, Elmeligy, Omar Abdelsadek Abdou, Elmonem, Mohamed, Elshaer, Mohammed, Elsohaby, Ibrahim, Emamverdi, Mehdi, Emeto, Theophilus, Endres, Matthias, Esezobor, Christopher Imokhuede, Eskandarieh, Sharareh, Fadaei, Abdolmajid, Fagbamigbe, Adeniyi Francis, Fahim, Ayesha, Faramarzi, Ali, Fares, Jawad, Farjoud Kouhanjani, Mohsen, Faro, Andre, Farzadfar, Farshad, Fatehizadeh, Ali, Fathi, Mobina, Fathi, Saeid, Fatima, Syeda Anum Fatima, Feizkhah, Alireza, Fereshtehnejad, Seyed-Mohammad, Ferrari, Alize, Ferreira, Nuno, Fetensa, Getahun, Firouraghi, Neda, Fischer, Florian, Fonseca, Ana Catarina, Force, Lisa, Fornari, Arianna, Foroutan, Behzad, Fukumoto, Takeshi, Gadanya, Muktar, Gaidhane, Abhay Motiramji, Galali, Yaseen, Galehdar, Nasrin, Gan, Quan, Gandhi, Aravind, Ganesan, Balasankar, Gardner, William, Garg, Naval, Gau, Shuo-Yan, Gautam, Rupesh, Gebre, Teshome, Gebrehiwot, Mesfin, Gebremeskel, Gebreamlak Gebremedhn, Gebreslassie, Haftay Gebremedhin, Getacher, Lemma, Ghaderi Yazdi, Bardiya, Ghadirian, Fataneh, Ghaffarpasand, Fariborz, Ghanbari, Reza, Ghasemi, Mohammadreza, Ghazy, Ramy Mohamed, Ghimire, Sailaja, Gholami, Ali, Gholamrezanezhad, Ali, Ghotbi, Elena, Ghozy, Sherief, Gialluisi, Alessandro, Gill, Paramjit Singh, Glasstetter, Logan, Gnedovskaya, Elena, Golchin, Ali, Golechha, Mahaveer, Goleij, Pouya, Golinelli, Davide, Gomes-Neto, Mansueto, Goulart, Alessandra, Goyal, Anmol, Gray, Richard, Grivna, Michal, Guadie, Habtamu Alganeh, Guan, Bin, Guarducci, Giovanni, Guicciardi, Stefano, Gunawardane, Damitha Asanga, Guo, Hanbing, Gupta, Bhawna, Gupta, Rajeev, Gupta, Sapna, Gupta, Veer Bala, Gupta, Vivek Kumar, Gutiérrez, Reyna Alma, Habibzadeh, Farrokh, Hachinski, Vladimir, Haddadi, Rasool, Hadei, Mostafa, Hadi, Najah, Haep, Nils, Haile, Teklehaimanot Gereziher, Haj-Mirzaian, Arvin, Hall, Brian, Halwani, Rabih, Hameed, Sajid, Hamiduzzaman, Mohammad, Hammoud, Ahmad, Han, Hannah, Hanifi, Nasrin, Hankey, Graeme, Hannan, Md. Abdul, Hao, Junwei, Harapan, Harapan, Hareru, Habtamu Endashaw, Hargono, Arief, Harlianto, Netanja, Haro, Josep Maria, Hartman, Nicholas Nathaniel, Hasaballah, Ahmed, Hasan, Faizul, Hasani, Hamidreza, Hasanian, Mohammad, Hassan, Amr, Hassan, Shoaib, Hassanipour, Soheil, Hassankhani, Hadi, Hassen, Mohammed Bheser, Haubold, Johannes, Hay, Simon, Hayat, Khezar, Hegazy, Mohamed, Heidari, Golnaz, Heidari, Mohammad, Heidari-Soureshjani, Reza, Hesami, Hamed, Hezam, Kamal, Hiraike, Yuta, Hoffman, Howard, Holla, Ramesh, Hopf, Kathleen Pillsbury, Horita, Nobuyuki, Hossain, Md Mahbub, Hossain, Md. Belal, Hossain, Sahadat, Hosseinzadeh, Hassan, Hosseinzadeh, Mehdi, Hostiuc, Sorin, Hu, Chengxi, Huang, Junjie, Huda, Md. Nazmul, Hussain, Javid, Hussein, Nawfal, Huynh, Hong-Han, Hwang, Bing-Fang, Ibitoye, Segun Emmanuel, Ilaghi, Mehran, Ilesanmi, Olayinka Stephen, Ilic, Irena, Ilic, Milena, Immurana, Mustapha, Iravanpour, Farideh, Islam, Sheikh Mohammed Shariful, Ismail, Faisal, Iso, Hiroyasu, Isola, Gaetano, Iwagami, Masao, Iwu, Chidozie, Iyer, Mahalaxmi, Jaan, Ali, Jacob, Louis, Jadidi-Niaragh, Farhad, Jafari, Mahboobeh, Jafarinia, Morteza, Jafarzadeh, Abdollah, Jahankhani, Kasra, Jahanmehr, Nader, Jahrami, Haitham, Jaiswal, Abhishek, Jakovljevic, Mihajlo, Jamora, Roland Dominic G, Jana, Somnath, Javadi, Nilofer, Javed, Saad, Javeed, Saad, Jayapal, Sathish Kumar, Jayaram, Shubha, Jiang, Heng, Johnson, Catherine Owens, Johnson, Walter, Jokar, Mohammad, Jonas, Jost, Joseph, Abel, Joseph, Nitin, Joshua, Charity Ehimwenma, Jürisson, Mikk, Kabir, Ali, Kabir, Zubair, Kabito, Gebisa Guyasa, Kadashetti, Vidya, Kafi, Fatemeh, Kalani, Rizwan, Kalantar, Farnaz, Kaliyadan, Feroze, Kamath, Ashwin, Kamath, Sagarika, Kanchan, Tanuj, Kandel, Amit, Kandel, Himal, Kanmodi, Kehinde Kazeem, Karajizadeh, Mehrdad, Karami, Jafar, Karanth, Shama, Karaye, Ibraheem, Karch, André, Karimi, Aliasghar, Karimi, Hanie, Karimi Behnagh, Arman, Kasraei, Hengameh, Kassebaum, Nicholas, Kauppila, Joonas, Kaur, Harkiran, Kaur, Navjot, Kayode, Gbenga, Kazemi, Foad, Keikavoosi-Arani, Leila, Keller, Cathleen, Keykhaei, Mohammad, Khadembashiri, Mohammad Amin, Khader, Yousef Saleh, Khafaie, Morteza Abdullatif, Khajuria, Himanshu, Khalaji, Amirmohammad, Khamesipour, Faham, Khammarnia, Mohammad, Khan, Maseer, Khan, Moien Ab, Khan, Yusra, Khan Suheb, Mahammed Ziauddin, Khanmohammadi, Shaghayegh, Khanna, Tripti, Khatab, Khaled, Khatatbeh, Haitham, Khatatbeh, Moawiah Mohammad, Khateri, Sorour, Khatib, Mahalaqua Nazli, Khayat Kashani, Hamid Reza, Khonji, Mohammad Saeid, Khorashadizadeh, Fatemeh, Khormali, Moein, Khubchandani, Jagdish, Kian, Saeid, Kim, Grace, Kim, Jihee, Kim, Min Seo, Kim, Yun Jin, Kimokoti, Ruth, Kisa, Adnan, Kisa, Sezer, Kivimäki, Mika, Kochhar, Sonali, Kolahi, Ali-Asghar, Koly, Kamrun Nahar, Kompani, Farzad, Koroshetz, Walter, Kosen, Soewarta, Kourosh Arami, Masoumeh, Koyanagi, Ai, Kravchenko, Michael, Krishan, Kewal, Krishnamoorthy, Vijay, Kuate Defo, Barthelemy, Kuddus, Md Abdul, Kumar, Ashish, Kumar, G Anil, Kumar, Manasi, Kumar, Nithin, Kumsa, Netsanet Bogale, Kundu, Satyajit, Kurniasari, Maria Dyah, Kusuma, Dian, Kuttikkattu, Ambily, Kyu, Hmwe Hmwe, La Vecchia, Carlo, Ladan, Muhammad Awwal, Lahariya, Chandrakant, Laksono, Tri, Lal, Dharmesh Kumar, Lallukka, Tea, Lám, Judit, Lami, Faris Hasan, Landires, Iván, Langguth, Berthold, Lasrado, Savita, Latief, Kamaluddin, Latifinaibin, Kaveh, Lau, Kathryn Mei-Ming, Laurens, Matthew, Lawal, Basira Kankia, Le, Long Khanh Dao, Le, Thao Thi Thu, Ledda, Caterina, Lee, Munjae, Lee, Sang-Woong, Lee, Seung Won, Lee, Wei-Chen, Lee, Yo Han, Leonardi, Matilde, Lerango, Temesgen, Li, Ming-Chieh, Li, Wei, Ligade, Virendra, Lim, Stephen, Linehan, Christine, Liu, Chaojie, Liu, Jue, Liu, Wei, Lo, Chun-Han, Lo, Warren David, Lobo, Stany, Logroscino, Giancarlo, Lopes, Graciliana, Lopukhov, Platon, Lorenzovici, László, Lorkowski, Stefan, Loureiro, Joana, Lubinda, Jailos, Lucchetti, Giancarlo, Lutzky Saute, Ricardo, Ma, Zheng Feei, Mabrok, Mahmoud, Machoy, Monika, Madadizadeh, Farzan, Magdy Abd El Razek, Mohammed, Maghazachi, Azzam, Maghbouli, Nastaran, Mahjoub, Soleiman, Mahmoudi, Morteza, Majeed, Azeem, Malagón-Rojas, Jeadran, Malakan Rad, Elaheh, Malhotra, Kashish, Malik, Ahmad Azam, Malik, Iram, Mallhi, Tauqeer Hussain, Malta, Deborah Carvalho, Manilal, Aseer, Mansouri, Vahid, Mansournia, Mohammad Ali, Marasini, Bishnu, Marateb, Hamid Reza, Maroufi, Seyed Farzad, Martinez-Raga, Jose, Martini, Santi, Martins-Melo, Francisco Rogerlândio, Martorell, Miquel, März, Winfried, Marzo, Roy Rillera, Massano, João, Mathangasinghe, Yasith, Mathews, Elezebeth, Maude, Richard James, Maugeri, Andrea, Maulik, Pallab, Mayeli, Mahsa, Mazaheri, Maryam, Mcalinden, Colm, Mcgrath, John, Meena, Jitendra Kumar, Mehndiratta, Man Mohan, Mendez-Lopez, Max Alberto Mendez, Mendoza, Walter, Mendoza-Cano, Oliver, Menezes, Ritesh, Merati, Mohsen, Meretoja, Atte, Merkin, Alexander, Mersha, Abera, Mestrovic, Tomislav, Mi, Tianyue, Miazgowski, Tomasz, Michalek, Irmina Maria, Mihretie, Ephrem Tesfaye, Minh, Le Huu Nhat, Mirfakhraie, Reza, Mirica, Andreea, Mirrakhimov, Erkin, Mirzaei, Mehdi, Misganaw, Awoke, Misra, Sanjeev, Mithra, Prasanna, Mizana, Biru Abdissa, Mohamadkhani, Ashraf, Mohamed, Nouh Saad, Mohammadi, Esmaeil, Mohammadi, Hiwa, Mohammadi, Shadieh, Mohammadi, Soheil, Mohammadshahi, Marita, Mohammed, Mustapha, Mohammed, Salahuddin, Mohammed, Shafiu, Mohan, Syam, Mojiri-Forushani, Hoda, Moka, Nagabhishek, Mokdad, Ali, Molinaro, Sabrina, Möller, Holger, Monasta, Lorenzo, Moniruzzaman, Md, Montazeri, Fateme, Moradi, Maryam, Moradi, Yousef, Moradi-Lakeh, Maziar, Moraga, Paula, Morovatdar, Negar, Morrison, Shane Douglas, Mosapour, Abbas, Mosser, Jonathan, Mossialos, Elias, Motaghinejad, Majid, Mousavi, Parsa, Mousavi, Seyed Ehsan, Mubarik, Sumaira, Muccioli, Lorenzo, Mughal, Faraz, Mukoro, George Duke, Mulita, Admir, Mulita, Francesk, Musaigwa, Fungai, Mustafa, Ahmad, Mustafa, Ghulam, Muthu, Sathish, Nagarajan, Ahamarshan Jayaraman, Naghavi, Pirouz, Naik, Ganesh, Nainu, Firzan, Nair, Tapas Sadasivan, Najmuldeen, Hastyar Hama Rashid, Nakhostin Ansari, Noureddin, Nambi, Gopal, Namdar Areshtanab, Hossein, Nargus, Shumaila, Nascimento, Bruno Ramos, Naser, Abdallah, Nashwan, Abdulqadir, Nasoori, Hadis, Nasreldein, Ahmed, Natto, Zuhair, Nauman, Javaid, Nayak, Biswa Prakash, Nazri-Panjaki, Athare, Negaresh, Mohammad, Negash, Hadush, Negoi, Ionut, Negoi, Ruxandra Irina, Negru, Serban Mircea, Nejadghaderi, Seyed Aria, Nematollahi, Mohammad Hadi, Nesbit, Olivia, Newton, Charles Richard James, Nguyen, Dang, Nguyen, Hau Thi Hien, Nguyen, Hien Quang, Nguyen, Ngoc-Trinh Thi, Nguyen, Phat Tuan, Nguyen, Van Thanh, Niazi, Robina Khan, Nikolouzakis, Taxiarchis Konstantinos, Niranjan, Vikram, Nnyanzi, Lawrence Achilles, Noman, Efaq Ali, Noroozi, Nafise, Norrving, Bo, Noubiap, Jean Jacques, Nri-Ezedi, Chisom Adaobi, Ntaios, George, Nuñez-Samudio, Virginia, Nurrika, Dieta, Oancea, Bogdan, Odetokun, Ismail, O'Donnell, Martin James, Ogunsakin, Ropo Ebenezer, Oguta, James Odhiambo, Oh, In-Hwan, Okati-Aliabad, Hassan, Okeke, Sylvester Reuben, Okekunle, Akinkunmi Paul, Okonji, Osaretin Christabel, Okwute, Patrick Godwin, Olagunju, Andrew, Olaiya, Muideen Tunbosun, Olana, Matifan Dereje, Olatubi, Matthew Idowu, Oliveira, Gláucia Maria Moraes, Olufadewa, Isaac Iyinoluwa, Olusanya, Bolajoko Olubukunola, Omar Bali, Ahmed, Ong, Sokking, Onwujekwe, Obinna, Ordak, Michal, Orji, Aislyn, Ortega-Altamirano, Doris, Osuagwu, Uchechukwu Levi, Otstavnov, Nikita, Otstavnov, Stanislav, Ouyahia, Amel, Owolabi, Mayowa, P A, Mahesh Padukudru, Pacheco-Barrios, Kevin, Padubidri, Jagadish Rao, Pal, Pramod Kumar, Palange, Padmavali Nanaji, Palladino, Claudia, Palladino, Raffaele, Palma-Alvarez, Raul Felipe, Pan, Feng, Panagiotakos, Demosthenes, Panda-Jonas, Songhomitra, Pandey, Anamika, Pandey, Ashok, Pandian, Jeyaraj Durai, Pangaribuan, Helena Ullyartha, Pantazopoulos, Ioannis, Pardhan, Shahina, Parija, Pragyan Paramita, Parikh, Romil, Park, Seoyeon, Parthasarathi, Ashwaghosha, Pashaei, Ava, Patel, Jay, Patil, Shankargouda, Patoulias, Dimitrios, Pawar, Shrikant, Pedersini, Paolo, Pensato, Umberto, Pereira, David, Pereira, Jeevan, Pereira, Maria Odete, Peres, Mario, Perico, Norberto, Perna, Simone, Petcu, Ionela-Roxana, Petermann-Rocha, Fanny Emily, Pham, Hoang Tran, Phillips, Michael, Pinilla-Monsalve, Gabriel, Piradov, Michael, Plotnikov, Evgenii, Poddighe, Dimitri, Polat, Burcu, Poluru, Ramesh, Pond, Constance Dimity, Poudel, Govinda Raj, Pouramini, Alireza, Pourbagher-Shahri, Ali Mohammad, Pourfridoni, Mohammad, Pourtaheri, Naeimeh, Prakash, Peralam Yegneswaran, Prakash, Sanjay, Prakash, V, Prates, Elton Junio Sady, Pritchett, Natalie, Purnobasuki, Hery, Qasim, Nameer Hashim, Qattea, Ibrahim, Qian, Gangzhen, Radhakrishnan, Venkatraman, Raee, Pourya, Raeisi Shahraki, Hadi, Rafique, Ibrar, Raggi, Alberto, Raghav, Pankaja Raghav, Rahati, Meghdad, Rahim, Fakher, Rahimi, Zahra, Rahimifard, Mahban, Rahman, Md Obaidur, Rahman, Mohammad Hifz Ur, Rahman, Mosiur, Rahman, Muhammad Aziz, Rahmani, Amir Masoud, Rahmani, Shayan, Rahmani Youshanlouei, Hamed, Rahmati, Masoud, Raj Moolambally, Sheetal, Rajabpour-Sanati, Ali, Ramadan, Hazem, Ramasamy, Shakthi Kumaran, Ramasubramani, Premkumar, Ramazanu, Sheena, Rancic, Nemanja, Rao, Indu Ramachandra, Rao, Sowmya, Rapaka, Deepthi, Rashedi, Vahid, Rashid, Ahmed Mustafa, Rashidi, Mohammad-Mahdi, Rashidi Alavijeh, Mehran, Rasouli-Saravani, Ashkan, Rawaf, Salman, Razo, Christian, Redwan, Elrashdy Moustafa Mohamed, Rekabi Bana, Atefe, Remuzzi, Giuseppe, Rezaei, Nazila, Rezaei, Negar, Rezaei, Nima, Rezaeian, Mohsen, Rhee, Taeho Gregory, Riad, Abanoub, Robinson, Stephen, Rodrigues, Mónica, Rodriguez, Jefferson Antonio Buendia, Roever, Leonardo, Rogowski, Emma, Romoli, Michele, Ronfani, Luca, Roy, Priyanka, Roy Pramanik, Koushik, Rubagotti, Enrico, Ruiz, Milagros, Russ, Tom, S Sunnerhagen, Katharina, Saad, Aly, Saadatian, Zahra, Saber, Korosh, Saberikamarposhti, Morteza, Sacco, Simona, Saddik, Basema, Sadeghi, Erfan, Sadeghian, Saeid, Saeed, Umar, Saeed, Usman, Safdarian, Mahdi, Safi, Sher Zaman, Sagar, Rajesh, Sagoe, Dominic, Saheb Sharif-Askari, Fatemeh, Saheb Sharif-Askari, Narjes, Sahebkar, Amirhossein, Sahoo, Soumya Swaroop, Sahraian, Mohammad Ali, Sajedi, Seyed Aidin, Sakshaug, Joseph, Saleh, Mohamed, Salehi Omran, Hossein, Salem, Marwa Rashad, Salimi, Sohrab, Samadi Kafil, Hossein, Samadzadeh, Sara, Samargandy, Saad, Samodra, Yoseph Leonardo, Samuel, Vijaya Paul, Samy, Abdallah, Sanadgol, Nima, Sanjeev, Rama Krishna, Sanmarchi, Francesco, Santomauro, Damian Francesco, Santri, Ichtiarini Nurullita, Santric-Milicevic, Milena, Saravanan, Aswini, Sarveazad, Arash, Satpathy, Maheswar, Saylan, Mete, Sayyah, Mehdi, Scarmeas, Nikolaos, Schlaich, Markus, Schuermans, Art, Schwarzinger, Michaël, Schwebel, David, Selvaraj, Siddharthan, Sendekie, Ashenafi Kibret, Sengupta, Pallav, Senthilkumaran, Subramanian, Serban, Dragos, Sergindo, Mihretu Tagesse, Sethi, Yashendra, Seyedalinaghi, Seyedahmad, Seylani, Allen, Shabani, Mohammad, Shabany, Maryam, Shafie, Mahan, Shahabi, Saeed, Shahbandi, Ataollah, Shahid, Samiah, Shahraki-Sanavi, Fariba, Shahsavari, Hamid, Shahwan, Moyad Jamal, Shaikh, Masood Ali, Shaji, Ks, Sham, Sunder, Shama, Adisu Tafari T, Shamim, Muhammad Aaqib, Shams-Beyranvand, Mehran, Shamsi, Mohammad Anas, Shanawaz, Mohd, Sharath, Medha, Sharfaei, Sadaf, Sharifan, Amin, Sharma, Manoj, Sharma, Rajesh, Shashamo, Bereket Beyene, Shayan, Maryam, Sheikhi, Rahim Ali, Shekhar, Shashank, Shen, Jiabin, Shenoy, Suchitra, Shetty, Pavanchand, Shiferaw, Desalegn Shiferaw, Shigematsu, Mika, Shiri, Rahman, Shittu, Aminu, Shivakumar, K, Shokri, Fereshteh, Shool, Sina, Shorofi, Seyed Afshin, Shrestha, Sunil, Siankam Tankwanchi, Akhenaten Benjamin, Siddig, Emmanuel Edwar, Sigfusdottir, Inga Dora, Silva, João Pedro, Silva, Luís Manuel Lopes Rodrigues, Sinaei, Ehsan, Singh, Balbir Bagicha, Singh, Garima, Singh, Paramdeep, Singh, Surjit, Sirota, Sarah Brooke, Sivakumar, Shravan, Sohag, Abdullah Al Mamun, Solanki, Ranjan, Soleimani, Hamidreza, Solikhah, Solikhah, Solomon, Yerukneh, Solomon, Yonatan, Song, Suhang, Song, Yimeng, Sotoudeh, Houman, Spartalis, Michael, Stark, Benjamin, Starnes, Joseph, Starodubova, Antonina, Stein, Dan, Steiner, Timothy, Stovner, Lars Jacob, Suleman, Muhammad, Suliankatchi Abdulkader, Rizwan, Sultana, Abida, Sun, Jing, Sunkersing, David, Sunny, Angel, Susianti, Hani, Swain, Chandan Kumar, Szeto, Mindy, Tabarés-Seisdedos, Rafael, Tabatabaei, Seyyed Mohammad, Tabatabai, Shima, Tabish, Mohammad, Taheri, Majid, Tahvildari, Azin, Tajbakhsh, Ardeshir, Tampa, Mircea, Tamuzi, Jacques Jl Lukenze, Tan, Ker-Kan, Tang, Haosu, Tareke, Minale, Tarigan, Ingan Ukur, Tat, Nathan, Tat, Vivian, Tavakoli Oliaee, Razieh, Tavangar, Seyed Mohammad, Tavasol, Arian, Tefera, Yibekal Manaye, Tehrani-Banihashemi, Arash, Temesgen, Worku Animaw, Temsah, Mohamad-Hani, Teramoto, Masayuki, Tesfaye, Amensisa Hailu, Tesfaye, Edosa Geta, Tesler, Riki, Thakali, Ocean, Thangaraju, Pugazhenthan, Thapa, Rajshree, Thapar, Rekha, Thomas, Nikhil Kenny, Thrift, Amanda, Ticoalu, Jansje Henny Vera, Tillawi, Tala, Toghroli, Razie, Tonelli, Marcello, Tovani-Palone, Marcos Roberto, Traini, Eugenio, Tran, Nghia Minh, Tran, Ngoc-Ha, Tran, Phu Van, Tromans, Samuel Joseph, Truelsen, Thomas Clement, Truyen, Thien Tan Tri Tai, Tsatsakis, Aristidis, Tsegay, Guesh Mebrahtom, Tsermpini, Evangelia Eirini, Tualeka, Abdul Rohim, Tufa, Derara Girma, Ubah, Chukwudi, Udoakang, Aniefiok John, Ulhaq, Inam, Umair, Muhammad, Umakanthan, Srikanth, Umapathi, Krishna Kishore, Unim, Brigid, Unnikrishnan, Bhaskaran, Vaithinathan, Asokan Govindaraj, Vakilian, Alireza, Valadan Tahbaz, Sahel, Valizadeh, Rohollah, van den Eynde, Jef, Vart, Priya, Varthya, Shoban Babu, Vasankari, Tommi Juhani, Vaziri, Siavash, Vellingiri, Balachandar, Venketasubramanian, Narayanaswamy, Verras, Georgios-Ioannis, Vervoort, Dominique, Villafañe, Jorge Hugo, Villani, Leonardo, Vinueza Veloz, Andres Fernando, Viskadourou, Maria, Vladimirov, Sergey Konstantinovitch, Vlassov, Vasily, Volovat, Simona Ruxandra, Vu, Loc Tri, Vujcic, Isidora, Wagaye, Birhanu, Waheed, Yasir, Wahood, Waseem, Walde, Mandaras Tariku, Wang, Fang, Wang, Shu, Wang, Yanzhong, Wang, Yuan-Pang, Waqas, Muhammad, Waris, Abdul, Weerakoon, Kosala Gayan, Weintraub, Robert, Weldemariam, Abrha Hailay, Westerman, Ronny, Whisnant, Joanna, Wickramasinghe, Dakshitha Praneeth, Wickramasinghe, Nuwan Darshana, Willekens, Barbara, Wilner, Lauren, Winkler, Andrea Sylvia, Wolfe, Charles, Wu, Ai-Min, Wulf Hanson, Sarah, Xu, Suowen, Xu, Xiaoyue, Yadollahpour, Ali, Yaghoubi, Sajad, Yahya, Galal, Yamagishi, Kazumasa, Yang, Lin, Yano, Yuichiro, Yao, Yao, Yehualashet, Sisay Shewasinad, Yeshaneh, Alex, Yesiltepe, Metin, Yi, Siyan, Yiğit, Arzu, Yiğit, Vahit, Yon, Dong Keon, Yonemoto, Naohiro, You, Yuyi, Younis, Mustafa, Yu, Chuanhua, Yusuf, Hadiza, Zadey, Siddhesh, Zahedi, Mohammad, Zakham, Fathiah, Zaki, Nazar, Zali, Alireza, Zamagni, Giulia, Zand, Ramin, Zandieh, Ghazal, Zangiabadian, Moein, Zarghami, Amin, Zastrozhin, Mikhail Sergeevich, Zeariya, Mohammed, Zegeye, Zelalem Banjaw, Zeukeng, Francis, Zhai, Chunxia, Zhang, Chen, Zhang, Haijun, Zhang, Yunquan, Zhang, Zhi-Jiang, Zhao, Hanqing, Zhao, Yang, Zheng, Peng, Zhou, Hengxing, Zhu, Bin, Zhumagaliuly, Abzal, Zielińska, Magdalena, Zikarg, Yossef Teshome, Zoladl, Mohammad, Murray, Christopher, Ong, Kanyin Liane, Feigin, Valery, Vos, Theo, Dua, Tarun

المساهمون: University of Washington Seattle, Johns Hopkins University School of Medicine Baltimore, Institute for Health Metrics and Evaluation University of Washington, Centre international de Recherche sur le Cancer (CIRC), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Laboratoire d'Informatique, du Traitement de l'Information et des Systèmes (LITIS), Université Le Havre Normandie (ULH), Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Institut national des sciences appliquées Rouen Normandie (INSA Rouen Normandie), Institut National des Sciences Appliquées (INSA)-Normandie Université (NU)-Institut National des Sciences Appliquées (INSA), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), Epidémiologie des Maladies Chroniques en zone tropicale (EpiMaCT), CHU Limoges-Institut d'Epidémiologie Neurologique et de Neurologie Tropicale-Institut National de la Santé et de la Recherche Médicale (INSERM)-OmégaHealth (ΩHealth), Université de Limoges (UNILIM)-Université de Limoges (UNILIM)

المصدر: ISSN: 1474-4422.

مصطلحات موضوعية: [SDV]Life Sciences [q-bio]

الوصف: International audience

العلاقة: hal-04543789; https://unilim.hal.science/hal-04543789Test; https://unilim.hal.science/hal-04543789/documentTest; https://unilim.hal.science/hal-04543789/file/1-s2.0-S1474442224000383-main.pdfTest

الإتاحة: https://doi.org/10.1016/s1474-4422Test(24)00038-3
https://unilim.hal.science/hal-04543789Test
https://unilim.hal.science/hal-04543789/documentTest
https://unilim.hal.science/hal-04543789/file/1-s2.0-S1474442224000383-main.pdfTest

المؤلفون: Steinmetz, Jaimie D, Seeher, Katrin Maria, Schiess, Nicoline, Nichols, Emma, Cao, Bochen, Servili, Chiara, Cavallera, Vanessa, Cousin, Ewerton, Hagins, Hailey, Moberg, Madeline E, Mehlman, Max L, Abate, Yohannes Habtegiorgis, Abbas, Jaffar, Abbasi, Madineh Akram, Abbasian, Mohammadreza, Abbastabar, Hedayat, Abdelmasseh, Michael, Abdollahi, Mohammad, Abdollahi, Mozhan, Abdollahifar, Mohammad-Amin, Abd-Rabu, Rami, Abdulah, Deldar Morad, Abdullahi, Auwal, Abedi, Aidin, Abedi, Vida, Abeldaño Zuñiga, Roberto Ariel, Abidi, Hassan, Abiodun, Olumide, Aboagye, Richard Gyan, Abolhassani, Hassan, Aboyans, Victor, Abrha, Woldu Aberhe, Abualhasan, Ahmed, Abu-Gharbieh, Eman, Aburuz, Salahdein, Adamu, Lawan Hassan, Addo, Isaac Yeboah, Adebayo, Oladimeji M, Adekanmbi, Victor, Adekiya, Tayo Alex, Adikusuma, Wirawan, Adnani, Qorinah Estiningtyas Sakilah, Adra, Saryia, Afework, Tsion, Afolabi, Aanuoluwapo Adeyimika, Afraz, Ali, Afzal, Saira, Aghamiri, Shahin, Agodi, Antonella, Agyemang-Duah, Williams, Ahinkorah, Bright Opoku, Ahmad, Aqeel, Ahmad, Danish, Ahmad, Sajjad, Ahmadzade, Amir Mahmoud, Ahmed, Ali, Ahmed, Ayman, Ahmed, Haroon, Ahmed, Jivan Qasim, Ahmed, Luai A, Ahmed, Muktar Beshir, Ahmed, Syed Anees, Ajami, Marjan, Aji, Budi, Ajumobi, Olufemi, Akade, Seyed Esma'il, Akbari, Morteza, Akbarialiabad, Hossein, Akhlaghi, Shiva, Akinosoglou, Karolina, Akinyemi, Rufus Olusola, Akonde, Maxwell, Al Hasan, Syed Mahfuz, Alahdab, Fares, AL-Ahdal, Tareq Mohammed Ali, Al-amer, Rasmieh Mustafa, Albashtawy, Mohammed, AlBataineh, Mohammad T, Aldawsari, Khalifah A, Alemi, Hediyeh, Alemi, Sharifullah, Algammal, Abdelazeem M, Al-Gheethi, Adel Ali Saeed, Alhalaiqa, Fadwa Alhalaiqa Naji, Alhassan, Robert Kaba, Ali, Abid, Ali, Endale Alemayehu, Ali, Liaqat, Ali, Mohammed Usman, Ali, Musa Mohammed, Ali, Rafat, Ali, Shahid, Ali, Syed Shujait Shujait, Ali, Zahid, Alif, Sheikh Mohammad, Alimohamadi, Yousef, Aliyi, Ahmednur Adem, Aljofan, Mohamad, Aljunid, Syed Mohamed, Alladi, Suvarna, Almazan, Joseph Uy, Almustanyir, Sami, Al-Omari, Basem, Alqahtani, Jaber S, Alqasmi, Ibrahim, Alqutaibi, Ahmed Yaseen, Al-Shahi Salman, Rustam, Altaany, Zaid, Al-Tawfiq, Jaffar A, Altirkawi, Khalid A, Alvis-Guzman, Nelson, Al-Worafi, Yaser Mohammed, Aly, Hany, Aly, Safwat, Alzoubi, Karem H, Amani, Reza, Amindarolzarbi, Alireza, Amiri, Sohrab, Amirzade-Iranaq, Mohammad Hosein, Amu, Hubert, Amugsi, Dickson A, Amusa, Ganiyu Adeniyi, Amzat, Jimoh, Ancuceanu, Robert, Anderlini, Deanna, Anderson, David B, Andrei, Catalina Liliana, Androudi, Sofia, Angappan, Dhanalakshmi, Angesom, Teklit W, Anil, Abhishek, Ansari-Moghaddam, Alireza, Anwer, Razique, Arafat, Mosab, Aravkin, Aleksandr Y, Areda, Demelash, Ariffin, Hany, Arifin, Hidayat, Arkew, Mesay, Ärnlöv, Johan, Arooj, Mahwish, Artamonov, Anton A, Artanti, Kurnia Dwi, Aruleba, Raphael Taiwo, Asadi-Pooya, Ali A, Asena, Tilahun Ferede, Asghari-Jafarabadi, Mohammad, Ashraf, Muhammad, Ashraf, Tahira, Atalell, Kendalem Asmare, Athari, Seyyed Shamsadin, Atinafu, Bantalem Tilaye Tilaye, Atorkey, Prince, Atout, Maha Moh'd Wahbi, Atreya, Alok, Aujayeb, Avinash, Avan, Abolfazl, Ayala Quintanilla, Beatriz Paulina, Ayatollahi, Haleh, Ayinde, Olatunde O, Ayyoubzadeh, Seyed Mohammad, Azadnajafabad, Sina, Azizi, Zahra, Azizian, Khalil, Azzam, Ahmed Y, Babaei, Mahsa, Badar, Muhammad, Badiye, Ashish D, Baghdadi, Soroush, Bagherieh, Sara, Bai, Ruhai, Baig, Atif Amin, Balakrishnan, Senthilkumar, Balalla, Shivanthi, Baltatu, Ovidiu Constantin, Banach, Maciej, Bandyopadhyay, Soham, Banerjee, Indrajit, Baran, Mehmet Firat, Barboza, Miguel A, Barchitta, Martina, Bardhan, Mainak, Barker-Collo, Suzanne Lyn, Bärnighausen, Till Winfried, Barrow, Amadou, Bashash, Davood, Bashiri, Hamideh, Bashiru, Hameed Akande, Basiru, Afisu, Basso, João Diogo, Basu, Sanjay, Batiha, Abdul-Monim Mohammad, Batra, Kavita, Baune, Bernhard T, Bedi, Neeraj, Begde, Ahmet, Begum, Tahmina, Behnam, Babak, Behnoush, Amir Hossein, Beiranvand, Maryam, Béjot, Yannick, Bekele, Alehegn, Belete, Melaku Ashagrie, Belgaumi, Uzma Iqbal, Bemanalizadeh, Maryam, Bender, Rose G, Benfor, Bright, Bennett, Derrick A, Bensenor, Isabela M, Berice, Betyna, Bettencourt, Paulo JG, Beyene, Kebede A, Bhadra, Abhishek, Bhagat, Devidas S, Bhangdia, Kayleigh, Bhardwaj, Nikha, Bhardwaj, Pankaj, Bhargava, Ashish, Bhaskar, Sonu, Bhat, Ajay Nagesh, Bhat, Vivek, Bhatti, Gurjit Kaur, Bhatti, Jasvinder Singh, Bhatti, Rajbir, Bijani, Ali, Bikbov, Boris, Bilalaga, Mariah Malak, Biswas, Atanu, Bitaraf, Saeid, Bitra, Veera R, Bjørge, Tone, Bodolica, Virginia, Bodunrin, Aadam Olalekan, Boloor, Archith, Braithwaite, Dejana, Brayne, Carol, Brenner, Hermann, Briko, Andrey, Bringas Vega, Maria L, Brown, Julie, Budke, Christine M, Buonsenso, Danilo, Burkart, Katrin, Burns, Richard A, Bustanji, Yasser, Butt, Muhammad Hammad, Butt, Nadeem Shafique, Butt, Zahid A, Cabral, Lucas Scotta, Caetano dos Santos, Florentino Luciano, Calina, Daniela, Campos-Nonato, Ismael R, Cao, Chao, Carabin, Hélène, Cárdenas, Rosario, Carreras, Giulia, Carvalho, Andre F, Castañeda-Orjuela, Carlos A, Casulli, Adriano, Catalá-López, Ferrán, Catapano, Alberico L, Caye, Arthur, Cegolon, Luca, Cenderadewi, Muthia, Cerin, Ester, Chacón-Uscamaita, Pamela R Uscamaita, Chan, Jeffrey Shi Kai, Chanie, Gashaw Sisay, Charan, Jaykaran, Chattu, Vijay Kumar, Chekol Abebe, Endeshaw, Chen, Hui, Chen, Jianqi, Chi, Gerald, Chichagi, Fatemeh, Chidambaram, Saravana Babu, Chimoriya, Ritesh, Ching, Patrick R, Chitheer, Abdulaal, Chong, Yuen Yu, Chopra, Hitesh, Choudhari, Sonali Gajanan, Chowdhury, Enayet Karim, Chowdhury, Rajiv, Christensen, Hanne, Chu, Dinh-Toi, Chukwu, Isaac Sunday, Chung, Eric, Coberly, Kaleb, Columbus, Alyssa, Comachio, Josielli, Conde, Joao, Cortesi, Paolo Angelo, Costa, Vera Marisa, Couto, Rosa AS, Criqui, Michael H, Cruz-Martins, Natália, Dabbagh Ohadi, Mohammad Amin, Dadana, Sriharsha, Dadras, Omid, Dai, Xiaochen, Dai, Zhaoli, D'Amico, Emanuele, Danawi, Hadi A, Dandona, Lalit, Dandona, Rakhi, Darwish, Amira Hamed, Das, Saswati, Das, Subasish, Dascalu, Ana Maria, Dash, Nihar Ranjan, Dashti, Mohsen, De la Hoz, Fernando Pio, de la Torre-Luque, Alejandro, De Leo, Diego, Dean, Frances E, Dehghan, Amin, Dehghan, Azizallah, Dejene, Hiwot, Demant, Daniel, Demetriades, Andreas K, Demissie, Solomon, Deng, Xinlei, Desai, Hardik Dineshbhai, Devanbu, Vinoth Gnana Chellaiyan, Dhama, Kuldeep, Dharmaratne, Samath Dhamminda, Dhimal, Meghnath, Dias da Silva, Diana, Diaz, Daniel, Dibas, Mahmoud, Ding, Delaney D, Dinu, Monica, Dirac, M Ashworth, Diress, Mengistie, Do, Thanh Chi, Do, Thao Huynh Phuong, Doan, Khanh Duy Khanh, Dodangeh, Milad, Doheim, Mohamed Fahmy, Dokova, Klara Georgieva, Dongarwar, Deepa, Dsouza, Haneil Larson, Dube, John, Duraisamy, Senbagam, Durojaiye, Oyewole Christopher, Dutta, Sulagna, Dziedzic, Arkadiusz Marian, Edinur, Hisham Atan, Eissazade, Negin, Ekholuenetale, Michael, Ekundayo, Temitope Cyrus, El Nahas, Nevine, El Sayed, Iman, Elahi Najafi, Mohammad Amin, Elbarazi, Iffat, Elemam, Noha Mousaad, Elgar, Frank J, Elgendy, Islam Y, Elhabashy, Hala Rashad, Elhadi, Muhammed, Elilo, Legesse Tesfaye, Ellenbogen, Richard G, Elmeligy, Omar Abdelsadek Abdou, Elmonem, Mohamed A, Elshaer, Mohammed, Elsohaby, Ibrahim, Emamverdi, Mehdi, Emeto, Theophilus I, Endres, Matthias, Esezobor, Christopher Imokhuede, Eskandarieh, Sharareh, Fadaei, Abdolmajid, Fagbamigbe, Adeniyi Francis, Fahim, Ayesha, Faramarzi, Ali, Fares, Jawad, Farjoud Kouhanjani, Mohsen, Faro, Andre, Farzadfar, Farshad, Fatehizadeh, Ali, Fathi, Mobina, Fathi, Saeid, Fatima, Syeda Anum Fatima, Feizkhah, Alireza, Fereshtehnejad, Seyed-Mohammad, Ferrari, Alize J, Ferreira, Nuno, Fetensa, Getahun, Firouraghi, Neda, Fischer, Florian, Fonseca, Ana Catarina, Force, Lisa M, Fornari, Arianna, Foroutan, Behzad, Fukumoto, Takeshi, Gadanya, Muktar A, Gaidhane, Abhay Motiramji, Galali, Yaseen, Galehdar, Nasrin, Gan, Quan, Gandhi, Aravind P, Ganesan, Balasankar, Gardner, William M, Garg, Naval, Gau, Shuo-Yan, Gautam, Rupesh K, Gebre, Teshome, Gebrehiwot, Mesfin, Gebremeskel, Gebreamlak Gebremedhn, Gebreslassie, Haftay Gebremedhin, Getacher, Lemma, Ghaderi Yazdi, Bardiya, Ghadirian, Fataneh, Ghaffarpasand, Fariborz, Ghanbari, Reza, Ghasemi, MohammadReza, Ghazy, Ramy Mohamed, Ghimire, Sailaja, Gholami, Ali, Gholamrezanezhad, Ali, Ghotbi, Elena, Ghozy, Sherief, Gialluisi, Alessandro, Gill, Paramjit Singh, Glasstetter, Logan M, Gnedovskaya, Elena V, Golchin, Ali, Golechha, Mahaveer, Goleij, Pouya, Golinelli, Davide, Gomes-Neto, Mansueto, Goulart, Alessandra C, Goyal, Anmol, Gray, Richard J, Grivna, Michal, Guadie, Habtamu Alganeh, Guan, Bin, Guarducci, Giovanni, Guicciardi, Stefano, Gunawardane, Damitha Asanga, Guo, Hanbing, Gupta, Bhawna, Gupta, Rajeev, Gupta, Sapna, Gupta, Veer Bala, Gupta, Vivek Kumar, Gutiérrez, Reyna Alma, Habibzadeh, Farrokh, Hachinski, Vladimir, Haddadi, Rasool, Hadei, Mostafa, Hadi, Najah R, Haep, Nils, Haile, Teklehaimanot Gereziher, Haj-Mirzaian, Arvin, Hall, Brian J, Halwani, Rabih, Hameed, Sajid, Hamiduzzaman, Mohammad, Hammoud, Ahmad, Han, Hannah, Hanifi, Nasrin, Hankey, Graeme J, Hannan, Md Abdul, Hao, Junwei, Harapan, Harapan, Hareru, Habtamu Endashaw, Hargono, Arief, Harlianto, Netanja I, Haro, Josep Maria, Hartman, Nicholas Nathaniel, Hasaballah, Ahmed I, Hasan, Faizul, Hasani, Hamidreza, Hasanian, Mohammad, Hassan, Amr, Hassan, Shoaib, Hassanipour, Soheil, Hassankhani, Hadi, Hassen, Mohammed Bheser, Haubold, Johannes, Hay, Simon I, Hayat, Khezar, Hegazy, Mohamed I, Heidari, Golnaz, Heidari, Mohammad, Heidari-Soureshjani, Reza, Hesami, Hamed, Hezam, Kamal, Hiraike, Yuta, Hoffman, Howard J, Holla, Ramesh, Hopf, Kathleen Pillsbury, Horita, Nobuyuki, Hossain, Md Mahbub, Hossain, Md Belal, Hossain, Sahadat, Hosseinzadeh, Hassan, Hosseinzadeh, Mehdi, Hostiuc, Sorin, Hu, Chengxi, Huang, Junjie, Huda, Md Nazmul, Hussain, Javid, Hussein, Nawfal R, Huynh, Hong-Han, Hwang, Bing-Fang, Ibitoye, Segun Emmanuel, Ilaghi, Mehran, Ilesanmi, Olayinka Stephen, Ilic, Irena M, Ilic, Milena D, Immurana, Mustapha, Iravanpour, Farideh, Islam, Sheikh Mohammed Shariful, Ismail, Faisal, Iso, Hiroyasu, Isola, Gaetano, Iwagami, Masao, Iwu, Chidozie CD, Iyer, Mahalaxmi, Jaan, Ali, Jacob, Louis, Jadidi-Niaragh, Farhad, Jafari, Mahboobeh, Jafarinia, Morteza, Jafarzadeh, Abdollah, Jahankhani, Kasra, Jahanmehr, Nader, Jahrami, Haitham, Jaiswal, Abhishek, Jakovljevic, Mihajlo, Jamora, Roland Dominic G, Jana, Somnath, Javadi, Nilofer, Javed, Saad, Javeed, Saad, Jayapal, Sathish Kumar, Jayaram, Shubha, Jiang, Heng, Johnson, Catherine Owens, Johnson, Walter D, Jokar, Mohammad, Jonas, Jost B, Joseph, Abel, Joseph, Nitin, Joshua, Charity Ehimwenma, Jürisson, Mikk, Kabir, Ali, Kabir, Zubair, Kabito, Gebisa Guyasa, Kadashetti, Vidya, Kafi, Fatemeh, Kalani, Rizwan, Kalantar, Farnaz, Kaliyadan, Feroze, Kamath, Ashwin, Kamath, Sagarika, Kanchan, Tanuj, Kandel, Amit, Kandel, Himal, Kanmodi, Kehinde Kazeem, Karajizadeh, Mehrdad, Karami, Jafar, Karanth, Shama D, Karaye, Ibraheem M, Karch, André, Karimi, Aliasghar, Karimi, Hanie, Karimi Behnagh, Arman, Kasraei, Hengameh, Kassebaum, Nicholas J, Kauppila, Joonas H, Kaur, Harkiran, Kaur, Navjot, Kayode, Gbenga A, Kazemi, Foad, Keikavoosi-Arani, Leila, Keller, Cathleen, Keykhaei, Mohammad, Khadembashiri, Mohammad Amin, Khader, Yousef Saleh, Khafaie, Morteza Abdullatif, Khajuria, Himanshu, Khalaji, Amirmohammad, Khamesipour, Faham, Khammarnia, Mohammad, Khan, Maseer, Khan, Moien AB, Khan, Yusra H, Khan Suheb, Mahammed Ziauddin, Khanmohammadi, Shaghayegh, Khanna, Tripti, Khatab, Khaled, Khatatbeh, Haitham, Khatatbeh, Moawiah Mohammad, Khateri, Sorour, Khatib, Mahalaqua Nazli, Khayat Kashani, Hamid Reza, Khonji, Mohammad Saeid, khorashadizadeh, Fatemeh, Khormali, Moein, Khubchandani, Jagdish, Kian, Saeid, Kim, Grace, Kim, Jihee, Kim, Min Seo, Kim, Yun Jin, Kimokoti, Ruth W, Kisa, Adnan, Kisa, Sezer, Kivimäki, Mika, Kochhar, Sonali, Kolahi, Ali-Asghar, Koly, Kamrun Nahar, Kompani, Farzad, Koroshetz, Walter J, Kosen, Soewarta, Kourosh Arami, Masoumeh, Koyanagi, Ai, Kravchenko, Michael A, Krishan, Kewal, Krishnamoorthy, Vijay, Kuate Defo, Barthelemy, Kuddus, Md Abdul, Kumar, Ashish, Kumar, G Anil, Kumar, Manasi, Kumar, Nithin, Kumsa, Netsanet Bogale, Kundu, Satyajit, Kurniasari, Maria Dyah, Kusuma, Dian, Kuttikkattu, Ambily, Kyu, Hmwe Hmwe, La Vecchia, Carlo, Ladan, Muhammad Awwal, Lahariya, Chandrakant, Laksono, Tri, Lal, Dharmesh Kumar, Lallukka, Tea, Lám, Judit, Lami, Faris Hasan, Landires, Iván, Langguth, Berthold, Lasrado, Savita, Latief, Kamaluddin, Latifinaibin, Kaveh, Lau, Kathryn Mei-Ming, Laurens, Matthew B, Lawal, Basira Kankia, Le, Long Khanh Dao, Le, Thao Thi Thu, Ledda, Caterina, Lee, Munjae, Lee, Sang-woong, Lee, Seung Won, Lee, Wei-Chen, Lee, Yo Han, Leonardi, Matilde, Lerango, Temesgen L, Li, Ming-Chieh, Li, Wei, Ligade, Virendra S, Lim, Stephen S, Linehan, Christine, Liu, Chaojie, Liu, Jue, Liu, Wei, Lo, Chun-Han, Lo, Warren David, Lobo, Stany W, Logroscino, Giancarlo, Lopes, Graciliana, Lopukhov, Platon D, Lorenzovici, László, Lorkowski, Stefan, Loureiro, Joana A, Lubinda, Jailos, Lucchetti, Giancarlo, Lutzky Saute, Ricardo, Ma, Zheng Feei, Mabrok, Mahmoud, Machoy, Monika, Madadizadeh, Farzan, Magdy Abd El Razek, Mohammed, Maghazachi, Azzam A, Maghbouli, Nastaran, Mahjoub, Soleiman, Mahmoudi, Morteza, Majeed, Azeem, Malagón-Rojas, Jeadran N, Malakan Rad, Elaheh, Malhotra, Kashish, Malik, Ahmad Azam, Malik, Iram, Mallhi, Tauqeer Hussain, Malta, Deborah Carvalho, Manilal, Aseer, Mansouri, Vahid, Mansournia, Mohammad Ali, Marasini, Bishnu P, Marateb, Hamid Reza, Maroufi, Seyed Farzad, Martinez-Raga, Jose, Martini, Santi, Martins-Melo, Francisco Rogerlândio, Martorell, Miquel, März, Winfried, Marzo, Roy Rillera, Massano, João, Mathangasinghe, Yasith, Mathews, Elezebeth, Maude, Richard James, Maugeri, Andrea, Maulik, Pallab K, Mayeli, Mahsa, Mazaheri, Maryam, McAlinden, Colm, McGrath, John J, Meena, Jitendra Kumar, Mehndiratta, Man Mohan, Mendez-Lopez, Max Alberto Mendez, Mendoza, Walter, Mendoza-Cano, Oliver, Menezes, Ritesh G, Merati, Mohsen, Meretoja, Atte, Merkin, Alexander, Mersha, Abera M, Mestrovic, Tomislav, Mi, Tianyue, Miazgowski, Tomasz, Michalek, Irmina Maria, Mihretie, Ephrem Tesfaye, Minh, Le Huu Nhat, Mirfakhraie, Reza, Mirica, Andreea, Mirrakhimov, Erkin M, Mirzaei, Mehdi, Misganaw, Awoke, Misra, Sanjeev, Mithra, Prasanna, Mizana, Biru Abdissa, Mohamadkhani, Ashraf, Mohamed, Nouh Saad, Mohammadi, Esmaeil, Mohammadi, Hiwa, Mohammadi, Shadieh, Mohammadi, Soheil, Mohammadshahi, Marita, Mohammed, Mustapha, Mohammed, Salahuddin, Mohammed, Shafiu, Mohan, Syam, Mojiri-forushani, Hoda, Moka, Nagabhishek, Mokdad, Ali H, Molinaro, Sabrina, Möller, Holger, Monasta, Lorenzo, Moniruzzaman, Md, Montazeri, Fateme, Moradi, Maryam, Moradi, Yousef, Moradi-Lakeh, Maziar, Moraga, Paula, Morovatdar, Negar, Morrison, Shane Douglas, Mosapour, Abbas, Mosser, Jonathan F, Mossialos, Elias, Motaghinejad, Majid, Mousavi, Parsa, Mousavi, Seyed Ehsan, Mubarik, Sumaira, Muccioli, Lorenzo, Mughal, Faraz, Mukoro, George Duke, Mulita, Admir, Mulita, Francesk, Musaigwa, Fungai, Mustafa, Ahmad, Mustafa, Ghulam, Muthu, Sathish, Nagarajan, Ahamarshan Jayaraman, Naghavi, Pirouz, Naik, Ganesh R, Nainu, Firzan, Nair, Tapas Sadasivan, Najmuldeen, Hastyar Hama Rashid, Nakhostin Ansari, Noureddin, Nambi, Gopal, Namdar Areshtanab, Hossein, Nargus, Shumaila, Nascimento, Bruno Ramos, Naser, Abdallah Y, Nashwan, Abdulqadir JJ, Nasoori, Hadis, Nasreldein, Ahmed, Natto, Zuhair S, Nauman, Javaid, Nayak, Biswa Prakash, Nazri-Panjaki, Athare, Negaresh, Mohammad, Negash, Hadush, Negoi, Ionut, Negoi, Ruxandra Irina, Negru, Serban Mircea, Nejadghaderi, Seyed Aria, Nematollahi, Mohammad Hadi, Nesbit, Olivia D, Newton, Charles Richard James, Nguyen, Dang H, Nguyen, Hau Thi Hien, Nguyen, Hien Quang, Nguyen, Ngoc-Trinh Thi, Nguyen, Phat Tuan, Nguyen, Van Thanh, Niazi, Robina Khan, Nikolouzakis, Taxiarchis Konstantinos, Niranjan, Vikram, Nnyanzi, Lawrence Achilles, Noman, Efaq Ali, Noroozi, Nafise, Norrving, Bo, Noubiap, Jean Jacques, Nri-Ezedi, Chisom Adaobi, Ntaios, George, Nuñez-Samudio, Virginia, Nurrika, Dieta, Oancea, Bogdan, Odetokun, Ismail A, O'Donnell, Martin James, Ogunsakin, Ropo Ebenezer, Oguta, James Odhiambo, Oh, In-Hwan, Okati-Aliabad, Hassan, Okeke, Sylvester Reuben, Okekunle, Akinkunmi Paul, Okonji, Osaretin Christabel, Okwute, Patrick Godwin, Olagunju, Andrew T, Olaiya, Muideen Tunbosun, Olana, Matifan Dereje, Olatubi, Matthew Idowu, Oliveira, Gláucia Maria Moraes, Olufadewa, Isaac Iyinoluwa, Olusanya, Bolajoko Olubukunola, Omar Bali, Ahmed, Ong, Sokking, Onwujekwe, Obinna E, Ordak, Michal, Orji, Aislyn U, Ortega-Altamirano, Doris V, Osuagwu, Uchechukwu Levi, Otstavnov, Nikita, Otstavnov, Stanislav S, Ouyahia, Amel, Owolabi, Mayowa O, P A, Mahesh Padukudru, Pacheco-Barrios, Kevin, Padubidri, Jagadish Rao, Pal, Pramod Kumar, Palange, Padmavali Nanaji, Palladino, Claudia, Palladino, Raffaele, Palma-Alvarez, Raul Felipe, Pan, Feng, Panagiotakos, Demosthenes, Panda-Jonas, Songhomitra, Pandey, Anamika, Pandey, Ashok, Pandian, Jeyaraj Durai, Pangaribuan, Helena Ullyartha, Pantazopoulos, Ioannis, Pardhan, Shahina, Parija, Pragyan Paramita, Parikh, Romil R, Park, Seoyeon, Parthasarathi, Ashwaghosha, Pashaei, Ava, Patel, Jay, Patil, Shankargouda, Patoulias, Dimitrios, Pawar, Shrikant, Pedersini, Paolo, Pensato, Umberto, Pereira, David M, Pereira, Jeevan, Pereira, Maria Odete, Peres, Mario FP, Perico, Norberto, Perna, Simone, Petcu, Ionela-Roxana, Petermann-Rocha, Fanny Emily, Pham, Hoang Tran, Phillips, Michael R, Pinilla-Monsalve, Gabriel D, Piradov, Michael A, Plotnikov, Evgenii, Poddighe, Dimitri, Polat, Burcu, Poluru, Ramesh, Pond, Constance Dimity, Poudel, Govinda Raj, Pouramini, Alireza, Pourbagher-Shahri, Ali Mohammad, Pourfridoni, Mohammad, Pourtaheri, Naeimeh, Prakash, Peralam Yegneswaran, Prakash, Sanjay, Prakash, V, Prates, Elton Junio Sady, Pritchett, Natalie, Purnobasuki, Hery, Qasim, Nameer Hashim, Qattea, Ibrahim, Qian, Gangzhen, Radhakrishnan, Venkatraman, Raee, Pourya, Raeisi Shahraki, Hadi, Rafique, Ibrar, Raggi, Alberto, Raghav, Pankaja Raghav, Rahati, Meghdad M, Rahim, Fakher, Rahimi, Zahra, Rahimifard, Mahban, Rahman, Md Obaidur, Rahman, Mohammad Hifz Ur, Rahman, Mosiur, Rahman, Muhammad Aziz, Rahmani, Amir Masoud, Rahmani, Shayan, Rahmani Youshanlouei, Hamed, Rahmati, Masoud, Raj Moolambally, Sheetal, Rajabpour-Sanati, Ali, Ramadan, Hazem, Ramasamy, Shakthi Kumaran, Ramasubramani, Premkumar, Ramazanu, Sheena, Rancic, Nemanja, Rao, Indu Ramachandra, Rao, Sowmya J, Rapaka, Deepthi, Rashedi, Vahid, Rashid, Ahmed Mustafa, Rashidi, Mohammad-Mahdi, Rashidi Alavijeh, Mehran, Rasouli-Saravani, Ashkan, Rawaf, Salman, Razo, Christian, Redwan, Elrashdy Moustafa Mohamed, Rekabi Bana, Atefe, Remuzzi, Giuseppe, Rezaei, Nazila, Rezaei, Negar, Rezaei, Nima, Rezaeian, Mohsen, Rhee, Taeho Gregory, Riad, Abanoub, Robinson, Stephen R, Rodrigues, Mónica, Rodriguez, Jefferson Antonio Buendia, Roever, Leonardo, Rogowski, Emma LB, Romoli, Michele, Ronfani, Luca, Roy, Priyanka, Roy Pramanik, Koushik, Rubagotti, Enrico, Ruiz, Milagros A, Russ, Tom C, S Sunnerhagen, Katharina, Saad, Aly MA, Saadatian, Zahra, Saber, Korosh, SaberiKamarposhti, Morteza, Sacco, Simona, Saddik, Basema, Sadeghi, Erfan, Sadeghian, Saeid, Saeed, Umar, Saeed, Usman, Safdarian, Mahdi, Safi, Sher Zaman, Sagar, Rajesh, Sagoe, Dominic, Saheb Sharif-Askari, Fatemeh, Saheb Sharif-Askari, Narjes, Sahebkar, Amirhossein, Sahoo, Soumya Swaroop, Sahraian, Mohammad Ali, Sajedi, Seyed Aidin, Sakshaug, Joseph W, Saleh, Mohamed A, Salehi Omran, Hossein, Salem, Marwa Rashad, Salimi, Sohrab, Samadi Kafil, Hossein, Samadzadeh, Sara, Samargandy, Saad, Samodra, Yoseph Leonardo, Samuel, Vijaya Paul, Samy, Abdallah M, Sanadgol, Nima, Sanjeev, Rama Krishna, Sanmarchi, Francesco, Santomauro, Damian Francesco, Santri, Ichtiarini Nurullita, Santric-Milicevic, Milena M, Saravanan, Aswini, Sarveazad, Arash, Satpathy, Maheswar, Saylan, Mete, Sayyah, Mehdi, Scarmeas, Nikolaos, Schlaich, Markus P, Schuermans, Art, Schwarzinger, Michaël, Schwebel, David C, Selvaraj, Siddharthan, Sendekie, Ashenafi Kibret, Sengupta, Pallav, Senthilkumaran, Subramanian, Serban, Dragos, Sergindo, Mihretu Tagesse, Sethi, Yashendra, SeyedAlinaghi, SeyedAhmad, Seylani, Allen, Shabani, Mohammad, Shabany, Maryam, Shafie, Mahan, Shahabi, Saeed, Shahbandi, Ataollah, Shahid, Samiah, Shahraki-Sanavi, Fariba, Shahsavari, Hamid R, Shahwan, Moyad Jamal, Shaikh, Masood Ali, Shaji, KS, Sham, Sunder, Shama, Adisu Tafari T, Shamim, Muhammad Aaqib, Shams-Beyranvand, Mehran, Shamsi, Mohammad Anas, Shanawaz, Mohd, Sharath, Medha, Sharfaei, Sadaf, Sharifan, Amin, Sharma, Manoj, Sharma, Rajesh, Shashamo, Bereket Beyene, Shayan, Maryam, Sheikhi, Rahim Ali, Shekhar, Shashank, Shen, Jiabin, Shenoy, Suchitra M, Shetty, Pavanchand H, Shiferaw, Desalegn Shiferaw, Shigematsu, Mika, Shiri, Rahman, Shittu, Aminu, Shivakumar, KM, Shokri, Fereshteh, Shool, Sina, Shorofi, Seyed Afshin, Shrestha, Sunil, Siankam Tankwanchi, Akhenaten Benjamin, Siddig, Emmanuel Edwar, Sigfusdottir, Inga Dora, Silva, João Pedro, Silva, Luís Manuel Lopes Rodrigues, Sinaei, Ehsan, Singh, Balbir Bagicha, Singh, Garima, Singh, Paramdeep, Singh, Surjit, Sirota, Sarah Brooke, Sivakumar, Shravan, Sohag, Abdullah Al Mamun, Solanki, Ranjan, Soleimani, Hamidreza, Solikhah, Solikhah, Solomon, Yerukneh, Solomon, Yonatan, Song, Suhang, Song, Yimeng, Sotoudeh, Houman, Spartalis, Michael, Stark, Benjamin A, Starnes, Joseph R, Starodubova, Antonina V, Stein, Dan J, Steiner, Timothy J, Stovner, Lars Jacob, Suleman, Muhammad, Suliankatchi Abdulkader, Rizwan, Sultana, Abida, Sun, Jing, Sunkersing, David, Sunny, Angel, Susianti, Hani, Swain, Chandan Kumar, Szeto, Mindy D, Tabarés-Seisdedos, Rafael, Tabatabaei, Seyyed Mohammad, Tabatabai, Shima, Tabish, Mohammad, Taheri, Majid, Tahvildari, Azin, Tajbakhsh, Ardeshir, Tampa, Mircea, Tamuzi, Jacques JL Lukenze, Tan, Ker-Kan, Tang, Haosu, Tareke, Minale, Tarigan, Ingan Ukur, Tat, Nathan Y, Tat, Vivian Y, Tavakoli Oliaee, Razieh, Tavangar, Seyed Mohammad, Tavasol, Arian, Tefera, Yibekal Manaye, Tehrani-Banihashemi, Arash, Temesgen, Worku Animaw, Temsah, Mohamad-Hani, Teramoto, Masayuki, Tesfaye, Amensisa Hailu, Tesfaye, Edosa Geta, Tesler, Riki, Thakali, Ocean, Thangaraju, Pugazhenthan, Thapa, Rajshree, Thapar, Rekha, Thomas, Nikhil Kenny, Thrift, Amanda G, Ticoalu, Jansje Henny Vera, Tillawi, Tala, Toghroli, Razie, Tonelli, Marcello, Tovani-Palone, Marcos Roberto, Traini, Eugenio, Tran, Nghia Minh, Tran, Ngoc-Ha, Tran, Phu Van, Tromans, Samuel Joseph, Truelsen, Thomas Clement, Truyen, Thien Tan Tri Tai, Tsatsakis, Aristidis, Tsegay, Guesh Mebrahtom, Tsermpini, Evangelia Eirini, Tualeka, Abdul Rohim, Tufa, Derara Girma, Ubah, Chukwudi S, Udoakang, Aniefiok John, Ulhaq, Inam, Umair, Muhammad, Umakanthan, Srikanth, Umapathi, Krishna Kishore, Unim, Brigid, Unnikrishnan, Bhaskaran, Vaithinathan, Asokan Govindaraj, Vakilian, Alireza, Valadan Tahbaz, Sahel, Valizadeh, Rohollah, Van den Eynde, Jef, Vart, Priya, Varthya, Shoban Babu, Vasankari, Tommi Juhani, Vaziri, Siavash, Vellingiri, Balachandar, Venketasubramanian, Narayanaswamy, Verras, Georgios-Ioannis, Vervoort, Dominique, Villafañe, Jorge Hugo, Villani, Leonardo, Vinueza Veloz, Andres Fernando, Viskadourou, Maria, Vladimirov, Sergey Konstantinovitch, Vlassov, Vasily, Volovat, Simona Ruxandra, Vu, Loc Tri, Vujcic, Isidora S, Wagaye, Birhanu, Waheed, Yasir, Wahood, Waseem, Walde, Mandaras Tariku, Wang, Fang, Wang, Shu, Wang, Yanzhong, Wang, Yuan-Pang, Waqas, Muhammad, Waris, Abdul, Weerakoon, Kosala Gayan, Weintraub, Robert G, Weldemariam, Abrha Hailay, Westerman, Ronny, Whisnant, Joanna L, Wickramasinghe, Dakshitha Praneeth, Wickramasinghe, Nuwan Darshana, Willekens, Barbara, Wilner, Lauren B, Winkler, Andrea Sylvia, Wolfe, Charles DA, Wu, Ai-Min, Wulf Hanson, Sarah, Xu, Suowen, Xu, Xiaoyue, Yadollahpour, Ali, Yaghoubi, Sajad, Yahya, Galal, Yamagishi, Kazumasa, Yang, Lin, Yano, Yuichiro, Yao, Yao, Yehualashet, Sisay Shewasinad, Yeshaneh, Alex, Yesiltepe, Metin, Yi, Siyan, Yiğit, Arzu, Yiğit, Vahit, Yon, Dong Keon, Yonemoto, Naohiro, You, Yuyi, Younis, Mustafa Z, Yu, Chuanhua, Yusuf, Hadiza, Zadey, Siddhesh, Zahedi, Mohammad, Zakham, Fathiah, Zaki, Nazar, Zali, Alireza, Zamagni, Giulia, Zand, Ramin, Zandieh, Ghazal GZ, Zangiabadian, Moein, Zarghami, Amin, Zastrozhin, Mikhail Sergeevich, Zeariya, Mohammed GM, Zegeye, Zelalem Banjaw, Zeukeng, Francis, Zhai, Chunxia, Zhang, Chen, Zhang, Haijun, Zhang, Yunquan, Zhang, Zhi-Jiang, Zhao, Hanqing, Zhao, Yang, Zheng, Peng, Zhou, Hengxing, Zhu, Bin, Zhumagaliuly, Abzal, Zielińska, Magdalena, Zikarg, Yossef Teshome, Zoladl, Mohammad, Murray, Christopher JL, Ong, Kanyin Liane, Feigin, Valery L, Vos, Theo, Dua, Tarun

المصدر: The Lancet Neurology , 23 (4) pp. 344-381. (2024)

الوصف: BACKGROUND: Disorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous publications from the Global Burden of Disease, Injuries, and Risk Factor Study estimated the burden of 15 neurological conditions in 2015 and 2016, but these analyses did not include neurodevelopmental disorders, as defined by the International Classification of Diseases (ICD)-11, or a subset of cases of congenital, neonatal, and infectious conditions that cause neurological damage. Here, we estimate nervous system health loss caused by 37 unique conditions and their associated risk factors globally, regionally, and nationally from 1990 to 2021. METHODS: We estimated mortality, prevalence, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life-years (DALYs), with corresponding 95% uncertainty intervals (UIs), by age and sex in 204 countries and territories, from 1990 to 2021. We included morbidity and deaths due to neurological conditions, for which health loss is directly due to damage to the CNS or peripheral nervous system. We also isolated neurological health loss from conditions for which nervous system morbidity is a consequence, but not the primary feature, including a subset of congenital conditions (ie, chromosomal anomalies and congenital birth defects), neonatal conditions (ie, jaundice, preterm birth, and sepsis), infectious diseases (ie, COVID-19, cystic echinococcosis, malaria, syphilis, and Zika virus disease), and diabetic neuropathy. By conducting a sequela-level analysis of the health outcomes for these conditions, only cases where nervous system damage occurred were included, and YLDs were recalculated to isolate the non-fatal burden directly attributable to nervous system health loss. A comorbidity correction was used to calculate total prevalence of all conditions that affect the nervous system combined. FINDINGS: Globally, the 37 ...

وصف الملف: application/pdf

العلاقة: https://discovery.ucl.ac.uk/id/eprint/10189389/1/Sunkersing_Global,%20regional,%20and%20national%20burden%20of%20disorders%20affecting%20the%20nervous%20system_VoR.pdfTest; https://discovery.ucl.ac.uk/id/eprint/10189389Test/

الإتاحة: https://discovery.ucl.ac.uk/id/eprint/10189389/1/Sunkersing_Global,%20regional,%20and%20national%20burden%20of%20disorders%20affecting%20the%20nervous%20system_VoR.pdfTest
https://discovery.ucl.ac.uk/id/eprint/10189389Test/

المؤلفون: Best, Jonathan G, Ambler, Gareth, Wilson, Duncan, Du, Houwei, Lee, Keon-Joo, Lim, Jae-Sung, Teo, Kay Cheong, Mak, Henry, Kim, Young Dae, Song, Tae-Jin, Selcuk Demirelli, Derya, Nishihara, Masashi, Yoshikawa, Masaaki, Kubacka, Marta, Zietz, Annaelle, Al-Shahi Salman, Rustam, Jäger, Hans Rolf, Lip, Gregory YH, Panos, Leonidas, Goeldlin, Martina B, Slater, Lee-Anne, Karayiannis, Christopher Charles, Phan, Thanh G, Bellut, Maximilian, Abrigo, Jill, Cheng, Cyrus, Leung, Thomas W, Chu, Winnie, Chappell, Francesca, Makin, Stephen DJ, van Dam-Nolen, Dianne HK, Kooi, M Eline, Köhler, Sebastian, Staals, Julie, Kuchcinski, Grégory, Bordet, Régis, Dubost, Florian, Wardlaw, Joanna M, Soo, Yannie OY, Fluri, Felix, Srikanth, Velandai K, Jung, Simon, Peters, Nils, Hara, Hideo, Yakushiji, Yusuke, Necioglu Orken, Dilek, Heo, Ji-Hoe, Lau, Gary Kui Kai, Bae, Hee-Joon, Werring, David J

المصدر: Neurology , 102 (1) , Article e207795. (2024)

الوصف: BACKGROUND AND OBJECTIVES: Visible perivascular spaces are an MRI marker of cerebral small vessel disease and might predict future stroke. However, results from existing studies vary. We aimed to clarify this through a large collaborative multicenter analysis. METHODS: We pooled individual patient data from a consortium of prospective cohort studies. Participants had recent ischemic stroke or transient ischemic attack (TIA), underwent baseline MRI, and were followed up for ischemic stroke and symptomatic intracranial hemorrhage (ICH). Perivascular spaces in the basal ganglia (BGPVS) and perivascular spaces in the centrum semiovale (CSOPVS) were rated locally using a validated visual scale. We investigated clinical and radiologic associations cross-sectionally using multinomial logistic regression and prospective associations with ischemic stroke and ICH using Cox regression. RESULTS: We included 7,778 participants (mean age 70.6 years; 42.7% female) from 16 studies, followed up for a median of 1.44 years. Eighty ICH and 424 ischemic strokes occurred. BGPVS were associated with increasing age, hypertension, previous ischemic stroke, previous ICH, lacunes, cerebral microbleeds, and white matter hyperintensities. CSOPVS showed consistently weaker associations. Prospectively, after adjusting for potential confounders including cerebral microbleeds, increasing BGPVS burden was independently associated with future ischemic stroke (versus 0-10 BGPVS, 11-20 BGPVS: HR 1.19, 95% CI 0.93-1.53; 21+ BGPVS: HR 1.50, 95% CI 1.10-2.06; p = 0.040). Higher BGPVS burden was associated with increased ICH risk in univariable analysis, but not in adjusted analyses. CSOPVS were not significantly associated with either outcome. DISCUSSION: In patients with ischemic stroke or TIA, increasing BGPVS burden is associated with more severe cerebral small vessel disease and higher ischemic stroke risk. Neither BGPVS nor CSOPVS were independently associated with future ICH.

وصف الملف: text

العلاقة: https://discovery.ucl.ac.uk/id/eprint/10184966/1/Clinical%20Associations%20and%20Prognostic%20Value.pdfTest; https://discovery.ucl.ac.uk/id/eprint/10184966Test/

الإتاحة: https://discovery.ucl.ac.uk/id/eprint/10184966/1/Clinical%20Associations%20and%20Prognostic%20Value.pdfTest
https://discovery.ucl.ac.uk/id/eprint/10184966Test/

المؤلفون: Wade, Julia, Farrar, Nicola, Realpe, Alba X., Donovan, Jenny L., Forsyth, Laura, Harkness, Kirsty A., Hutchinson, Peter J.A., Kitchen, Neil, Lewis, Steff C., Loan, James J.M., Stephen, Jacqueline, Al-Shahi Salman, Rustam, Mallucci, Conor, White, Philip M., Eriksson, Madeleine, Hayat, Raza, Kinsella, Elaine, Lewis, Katherine, Neilson, Aileen R., White, David C.S., Boyd, Julia, Bullen, Alastair, Maclean, Morag, Stoddart, Andrew, Phair, Sandra, Evans, Helen, Noakes, Jo, Alexander, Debra, Keerie, Catriona, Linsley, Christopher, Milne, Garry, Norrie, John, Bunch, Janet, Douthwaite, Kathryn, Temple, Simon, Hogg, James, Scott, David, Spallone, Pat, Stuart, Ian, Wardlaw, Joanna M., Palmer, Jeb, Sakka, Eleni, Mukerji, Nitin, Cirstea, Emanuel, Davies, Susan, Giannakaki, Venetia, Kadhim, Ammar, Kennion, Oliver, Islam, Moidul, Ferguson, Lucie

المصدر: eClinicalMedicine ; page 102557 ; ISSN 2589-5370

مصطلحات موضوعية: General Medicine

الإتاحة: https://doi.org/10.1016/j.eclinm.2024.102557Test
https://api.elsevier.com/content/article/PII:S2589537024001366?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2589537024001366?httpAccept=text/plainTest

المؤلفون: Vacek, Adam, Mair, Grant, White, Philip, Bath, Philip M, Muir, Keith W, Al-Shahi Salman, Rustam, Martin, Chloe, Dye, David, Chappell, Francesca M, von Kummer, Rüdiger, Macleod, Malcolm, Sprigg, Nikola, Wardlaw, Joanna M

المساهمون: Medical Research Council, Stroke Association

المصدر: Journal of Stroke and Cerebrovascular Diseases ; volume 33, issue 1, page 107512 ; ISSN 1052-3057

مصطلحات موضوعية: Cardiology and Cardiovascular Medicine, Neurology (clinical), Rehabilitation, Surgery

الإتاحة: https://doi.org/10.1016/j.jstrokecerebrovasdis.2023.107512Test
https://api.elsevier.com/content/article/PII:S1052305723005335?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S1052305723005335?httpAccept=text/plainTest

المؤلفون: Moullaali, Tom J, Wang, Xia, Sandset, Else Charlotte, Woodhouse, Lisa J, Law, Zhe Kang, Arima, Hisatomi, Butcher, Kenneth S, Chalmers, John, Delcourt, Candice, Edwards, Leon, Gupta, Salil, Jiang, Wen, Koch, Sebastian, Potter, John, Qureshi, Adnan I, Robinson, Thompson G, Al-Shahi Salman, Rustam, Saver, Jeffrey L, Sprigg, Nikola, Wardlaw, Joanna M, Anderson, Craig S, Bath, Philip M

المصدر: Journal of Neurology Neurosurgery & Psychiatry. 93(1)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Clinical Research, Clinical Trials and Supportive Activities, Evaluation of treatments and therapeutic interventions, 6.1 Pharmaceuticals, Good Health and Well Being, Adult, Aged, Antihypertensive Agents, Blood Pressure, Cerebral Hemorrhage, Female, Humans, Hypertension, Male, Middle Aged, Randomized Controlled Trials as Topic, Treatment Outcome, stroke, meta-analysis, Blood Pressure in Acute Stroke (BASC) Investigators, Medical and Health Sciences, Psychology and Cognitive Sciences, Neurology & Neurosurgery, Clinical sciences, Neurosciences

الوصف: ObjectiveTo summarise evidence of the effects of blood pressure (BP)-lowering interventions after acute spontaneous intracerebral haemorrhage (ICH).MethodsA prespecified systematic review of the Cochrane Central Register of Controlled Trials, EMBASE and MEDLINE databases from inception to 23 June 2020 to identify randomised controlled trials that compared active BP-lowering agents versus placebo or intensive versus guideline BP-lowering targets for adults 6 mL) and proportional (>33%) haematoma growth at 24 hours. Meta-analysis used a one-stage approach, adjusted using generalised linear mixed models with prespecified covariables and trial as a random effect.ResultsOf 7094 studies identified, 50 trials involving 11 494 patients were eligible and 16 (32.0%) shared patient-level data from 6221 (54.1%) patients (mean age 64.2 [SD 12.9], 2266 [36.4%] females) with a median time from symptom onset to randomisation of 3.8 hours (IQR 2.6-5.3). Active/intensive BP-lowering interventions had no effect on the primary outcome compared with placebo/guideline treatment (adjusted OR for unfavourable shift in modified Rankin scale scores: 0.97, 95% CI 0.88 to 1.06; p=0.50), but there was significant heterogeneity by strategy (pinteraction=0.031) and agent (pinteraction6 ml, adjusted OR 0.75, 95%CI 0.60 to 0.92; p=0.0077) and relative (≥33%, adjusted OR 0.82, 95%CI 0.68 to 0.99; p=0.034) haematoma growth.InterpretationOverall, a broad range of interventions to lower BP within 7 days of ICH onset had no overall benefit on functional recovery, despite reducing bleeding. The treatment effect appeared to vary according to strategy and agent.Prospero registration numberCRD42019141136.

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7808n32hTest