نتائج البحث

1

دورية أكاديمية

Unsupervised learning to characterize patients with known coronary artery disease undergoing myocardial perfusion imaging.

المؤلفون: Williams MC, Bednarski BP, Pieszko K, Miller RJH, Kwiecinski J, Shanbhag A, Liang JX, Huang C, Sharir T, Dorbala S, Di Carli MF, Einstein AJ, Sinusas AJ, Miller EJ, Bateman TM, Fish MB, Ruddy TD, Acampa W, Hauser MT, Kaufmann PA, Dey D, Berman DS, Slomka PJ.

المساهمون: Williams, Mc, Bednarski, Bp, Pieszko, K, Miller, Rjh, Kwiecinski, J, Shanbhag, A, Liang, Jx, Huang, C, Sharir, T, Dorbala, S, Di Carli, Mf, Einstein, Aj, Sinusas, Aj, Miller, Ej, Bateman, Tm, Fish, Mb, Ruddy, Td, Acampa, W, Hauser, Mt, Kaufmann, Pa, Dey, D, Berman, D, Slomka, Pj.

العلاقة: info:eu-repo/semantics/altIdentifier/wos/WOS:000974146000001; journal:EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING; https://hdl.handle.net/11588/921211Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85153032278

الإتاحة: https://doi.org/10.1007/s00259-023-06218-zTest
https://hdl.handle.net/11588/921211Test

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2

دورية أكاديمية

Worldwide Disparities in Recovery of Cardiac Testing 1 Year Into COVID-19

المؤلفون: Einstein A. J., Hirschfeld C., Williams M. C., Vitola J. V., Better N., Villines T. C., Cerci R., Shaw L. J., Choi A. D., Dorbala S., Karthikeyan G., Lu B., Sinitsyn V., Ansheles A. A., Kudo T., Bucciarelli-Ducci C., Norgaard B. L., Maurovich-Horvat P., Campisi R., Milan E., Louw L., Allam A. H., Bhatia M., Sewanan L., Malkovskiy E., Cohen Y., Randazzo M., Narula J., Morozova O., Pascual T. N. B., Pynda Y., Dondi M., Paez D., Hinterleitner G., Lu Y., Xu Z., Hirschfeld C. B., Erinne I., Shetty M., Choi A., Lopez-Mattei J., Parwani P., Goda A., Shirka E., Bouyoucef S., Chelghoum L., Mansouri F., Medjahedi A., Naili Q., Ridouh M., Alasia D., Alberghina L., Aramayo N., Buchara D., Busso F. G., Bustos Rivadero J. J., Camilletti J., Campanelli H., Castro R. B., Daicz M., del Riego H., Dragonetti L., Echazarreta D., Erriest J., Faccio F., Facello A., Gallegos H., Geronazzo R., Glait H., Hasbani V., Jager V., Lewkowicz J. M., Lotti J., Maciel N., Masoli O., Mastrovito E., Medus M., Merani M. F., Molteni S., Montecinos M., Parisi G., Sueldo C. P., Perez de Arenaza D., Quintana L., Radzinschi A., Redruello M., Rodriguez M., Rojas H., Acuna A. R., Schere D., Traverso S., Vazquez G., Zeffiro S., Sakanyan M., Beuzeville S., Boktor R., Crowley M., Downie D. A., Dwivedi G., Elison B., Farouque O., Jasper K., Joshi S., Lee J., Lee K., Lui E., Mcconachie P., Meaker J., Nandurkar D., Neill J., O'Rourke E., O'Sullivan P., Pandos G., Premaratne M., Prior D., Rutherford N., Saunders C., Taubman K., Tauro A., Taylor A., Theuerle J., Thomas P., Tow J., Upton A., Vamadevan S., Wayne V., Wegner E. A., Wong D., Younger J., Beitzke D., Feuchtner G., Sommer O., Weiss K., Maroz-Vadalazhskaya N., Tserakhau U., Homans F., Van De Heyning C. M., Araujo R., Soldat-Stankovic V., Stankovic S., Almeida A., Anselmi C., Azevedo G. S. A., Bittencourt M. S., Pianta D. B., Cabeda E., Carreira L., Coelho I., de Amorim Fernandes F., de Lorenzo A., Delgado R., Erthal F., Fernandes F., Fernandes J., Ferreira de Souza T., Foppa M., Matos Alves W. F., Gontijo C., Gottlieb I., Grossman G., Albernaz Siqueira M. H., Nomura C. H., Koga K. H., Lima R., Lopes R., Marcal Filho H. H., Masiero P., Mastrocola L., Menezes de Siqueira M. E., Mesquita C., Naves D., Penna F., Pinto I., Rocha T., Rocha J. L., Rodrigues A., Salioni L., Sanches A., Santos M., Da Silva L. S., Schvartzman P., Matushita C. S., Senra T., Silva M., Soares C. E., Spiro B., Suaide Silva C. E., Torres R., Monte G. U., Vilela A., Villa A. V., Vitola J., Voss T., Waltrick R., Zapparoli M., Naseer H., Garcheva-Tsacheva M., Ouattara T. F., Thou S., Varoeun S., Abikhzer G., Beanlands R., Chetrit M., Dabreo D., Dennie C., Friedrich M., Hafez M. N., Hanneman K., Miller R., Oikonomou A., Roifman I., Small G., Tandon V., Trivedi A., White J., Zukotynski K., Alay R., Concha C., Massardo T., Abad P., Anzola K., Arturo H., Benitez L., Cadena A., Zamudio C. C., Calderon A., Gutierrez Villamil C. T., Jaimes C., Londono J. L., Lopez N., Merlano-Gaitan S., Murgieitio-Cabrera R., Valencia M., Vergel D., Santamaria A. Z., Solis F., Batinic T., Franceschi M., Paar M. H., Prpic M., Felipe Batista C. J., Cabrera L. O., Peix A., Pena Y., Rochela Vazquez L. M., Ntalas I., Kaminek M., Kincl V., Lang O., Abdulla J., Bottcher M., Busk M., Geisler U., Gormsen L. C., Hansson N., Hess S., Hove J., Jensen L. T., Jensen M. T., Kragholm K. H., Ovrehus K., Rasmussen J., Ronnow Sand N. P., Sondergaard H., Zaremba T., Speckter H., Amores N., Velez M. S., Alrahman T. A., Elsamad S. A., Abdelfattah A., Allam A., Elkaffas S., Hassan M., Hussein E., Ibrahim A., Kandeel A., Ali M. M., Shaaban M., Flores C., Gomez Leiva V. V., Liiver A., Larikka M., Uusitalo V., Agostini D., Berger C., Dietz M., Hyafil F., Ohana M., Prigent K., Regaieg H., Sarda-Mantel L., H-Ici D. O., Ayetey H., Angelidis G., Fragkaki C., Fragkiadaki C., Georgoulias P., Koutelou M., Kyrozi E., Lama N., Prassopoulos V., Spartalis M., Zaglavara T., Gonzalez C., Gutierrez G., Maldonado A., Martinez Y., Kovacs A., Szilveszter B., Banthia N., Bhat V., Choudhury P., Chowdekar V. S., Christopher J., Garg T., Goyal N. K., Gupta R. K., Gupta A., Hephzibah J., Jain S., Krupa J., Kumar P., Kumar S., Lalchandani A., Mishra A., Mishra V. D., Mohan P., Ozair A., Pandey S., Parameswaran R., Patel C., Patel T., Patel S., Vimala L. R., Kumar Sarangi D. P., Sengupta S., Sethi A., Sharma A., Sharma A. K., Sharma P., Shrigiriwar A., Singh S., Singh H., Sood A., Verma A., Vyas A., Soeriadi E. A., Bun E., Hutomo F., Syawaluddin H., Yudistiro R., Albadr A., Assadi M., Emami F., Emami-Ardekani A., Farzanehfar S., Jafari R., Manafi-Farid R., Tajik M., Arnson Y., Fuchs S., Goldkorn R., Kennedy J., Leitman M., Shalev A., Acampa W., Albano D., Alongi P., Arnone G., Assante R., Baritussio A., Bauckneht M., Bianco F., Bonfiglioli R., Bovenzi F., Bruno I., Bruno A., Busnardo E., Califaretti E., Casoni R., Censullo V., Chierichetti F., Chiocchi M., Cittanti C., Clemente A., Cuocolo A., De Rimini M. L., De Vincentis G., Della Tommasina V., Dellegrottaglie S., Erba P. A., Evangelista L., Faggi L., Faragasso E., Florimonte L., Frantellizzi V., Gatti M., Gaudiano A., Gelardi F., Gerali A., Gimelli A., Guglielmo M., Leccisotti L., Liga R., Liguori C., Longo G., Maffione M., Marcassa C., Matassa G., Mele D., Mircoli L., Paccagnella A., Pacella S., Padovano F., Pellegrini D., Pergola V., Pugliese L., Quartuccio N., Rampin L., Ricci F., Rubini G., Russo V., Sambuceti G., Scatteia A., Sciagra R., Spidalieri G., Stefanelli A., Tedeschi C., Ventroni G., Baugh D., Madu E., Aikawa T., Asano H., Fujimoto S., Fujise K., Fukushima Y., Fukuyama K., Ichikawa Y., Ideguchi R., Iguchi N., Imai M., Ishimura H., Isobe S., Ito K., Izawa Y., Kadokami T., Kasai T., Kato T., Kawamoto T., Kiryu S., Kumita S., Manabe O., Maruno H., Matsumoto N., Miyagawa M., Moroi M., Nagamachi S., Nakajima K., Nakazato R., Nanasato M., Naya M., Norikane T., Ohta Y., Otomi Y., Otsuka H., Oyama-Manabe N., Saito M., Sarai M., Sato J., Sato D., Shiraishi S., Takanami K., Takehana K., Taniguchi Y., Teragawa H., Tomizawa N., Umeji K., Wakabayashi Y., Yamada S., Yamazaki S., Yoneyama T., Rawashdeh M., Dautov T., Makhdomi K., Abass M., Garashi M., Siraj Q., Kalnina M., Haidar M., Komiagiene R., Kviecinskiene G., Vajauskas D., Karim N. K. A., Doucoure M., Reichmuth L., Samuel A., Dieng M. L., Naojee A. S., Hernandez E. A., Alducin Tellez C. R., Alexanderson-Rosas E., Barragan E., Cabada M., Calderon D., Carvajal-Juarez I., Esparza J., Gama-Moreno M. G., Quinto V. G., Gonzalez N. C., Herrera-Zarza M. C., Meave A., Medina Verdugo J. G., Melendez G., Morales Murguia R. H., Navarro Quiroz C. S., Ornelas M., Preciado-Anaya A., Preciado-Gutierrez O. U., Puente A., Salazar A. R., Rosales Uvera S. G., Rosales-Uvera S., Serna Macias J. A., Sierra-Galan L., Sierra-Galan L. M., Tirado Alderete J. C., Vallejo E., Faraggi M., Sereegotov E., Ben Rais N., Alaoui N. I., Kyiphyu T., Oo S. T., Win S. M., Zar H., Ghimire R., Neupane M., Glaudemans A., Slart R., Verschure D., Allen B., Edmond J., Mckenzie C., Tie S., Van Pelt N., Worthington K., Young C., Soli I. A., Kana S., Onubogu U., Sani M., Braten A. T., Jorgensen A., Vassbotn H. -E., Al Dhuhli H., Jawa Z., Tag N., Fatima S., Imran M. B., Younis M. N., Saadullah M., Malo Y. H., Lenturut-Katal D., Castillo M., Ortellado J., Akhter A., Cader F. A., Hussain R., Khan S. R., Mandal T., Nasreen F., An Y., Cao D., Gong L., Hou Y., Jia C., Li T., Li C., Liu H., Liu W., Liu J., Ng M. -Y., Shi H., Tang C., Wang X., Wang Z., Wang Y., Wu J., Yi Y., Yuan L., Zhang T., Zhang L., Chavez E., Cruz C., Llontop C., Morales R., Abrihan P., Bustos-Barroso A., Duldulao-Ogbac M., Eduarte C., Obaldo J., Quinon A., San Juan B., San Juan C. J., Sauler-Gomez M. R., Uy M., Kostkiewicz M., Kunikowska J., Teresinska A., Urbanik T., Bettencourt N., Fontes-Carvalho R., Gavina C., Goncalves L., Macedo F., Moreno N., Sousa C., Timoteo A. T., Vidigal M. J., Al Heidous M., Ramanathan S., Arnous S., Aytani S., Byrne A., Gleeson T., Kerins D., O'Brien J., Bang J. -I., Bom H., Cheon M., Cheon G. J., Cho S. -G., Hong C. M., Jeong Y. H., Kang W. J., Kang Y. -K., Kim J. -Y., Oh S. W., So Y., Song H. -C., Won K. S., Yoo S. W., Mitevska I., Vavlukis M., Salobir B. G., Stalc M., Benedek T., Pop M., Stan C., Ansheles A., Dariy O., Gagarina N., Itskovich I., Karalkin A., Kokov A., Marina G., Migunova E., Pospelov V., Ryzhkova D., Sayfullina G., Sergienko V., Shurupova I., Vakhromeeva M., Valiullina N., Zavadovsky K., Zhuravlev K., Abazid R., Al Garni T., Alasnag M., Aljizeeri A., Amer H., Amro A., Hamdy H., Smettei O., Saranovic D. S., Vlajkovic M., Keng F., See J., Berecova Z., Mistinova J. P., Evbuomwan O., Govender N., Hack J., Hadebe B., Hlongwa K., Kaplan M., Lakhi H., Milos K., Modiselle M., More S., Muambadzi N., Scholtz L., Barreiro-Perez M., Blanco I., Broncano J., Camarero A., Casans-Tormo I., De Haro J., Flotats A., Garcia E., Mendiguchia C. G., Jimenez-Heffernan A., Leta R., Diaz J. L., Vega L. L., Manovel-Sanchez A., Monzonis A. M., Patrut B., Pubul V., Perez R. R., Zeidan N., Nanayakkara D., Suliman A., Engblom H., Murtadha M., Ostenfeld E., Simonsson M., Alkadhi H., Buechel R. R., Burger P., Grani C., Kamani C., Kawel-Bohm N., Klaeser B., Manka R., Prior J., Kaewchur T., Khiewvan B., Kositwattanarerk A., Namwongprom S., Thientunyakit T., Sayman H. B., Yuksel M., Sebikali M. J., Okello E., Korol P., Noverko I., Satyr M., Ahmad T., Alfakih K., Andrade I., Buckingham S., Bularga A., Carpenter J. -P., Cole G., Cusack D., David S., Davis P., Fairbairn T., Ghosh A., Ramkumar P. G., Hamilton M., Haque F., Hudson B., Johnstone A., Karthikeyan V. J., Kay M., Khan M. A., Kitt J., Low C. S., Mcalindon E., Mccreavy D., Morrissey B., Motwani M., Na D., Nicol E., Patel D., Rodrigues J., Rofe C., Schofield R., Semple T., Sheikh A., Sinha A., Subedi D., Topping W., Tweed K., Underwood S. R., Weir-Mccall J., Zuhairy H., Abbasi T., Abohashem S., Abramson S., Al-Mallah M., Kumar M. A., Balmer-Swain M., Berman D., Bernheim A., Bhatti S., Biederman R., Bieging E., Bingham S., Bloom S., Blue S., Borges A., Branch K., Bravo P., Buddhe S., Budoff M., Bullock-Palmer R., Cahill M., Candela C., Cao J., Chatterjee S., Chatzizisis Y., Chaudhuri N. R., Cheezum M., Chelliah A., Chen T., Chen M., Chen L., Chokshi A., Chung J., Danciu S., DeSisto W., Dilorenzo M., Doukky R., Duvall W., Ferencik M., Foster C., Fuisz A., Gannon M., German D., Gerson M., Geske J., Hage F., Haider A., Haider S., Hamirani Y., Hassen K., Hendel R., Henkel J., Horgan S., Hyun M., Janardhanan R., Jerome S., Kalra D., Kassop D., Kinkhabwala M., Kinzfogl G., Koch B., Koweek L., Krepp J., Kwon Y., Layer J., Lesser J., Leung S., Lisske B., Magurany K., Markowitz J., Mccullough B., Moalemi A., Moffitt C., Montanez J., Moore W., Morayati S., Mossa-Basha M., Mrsic Z., Murthy V., Nagpal P., Nelson K., Nijjar P., O'Quinn R., Passen E., Patil P., Pursnani A., Quachang N., Rabbat M., Ranjan P., Lozano P. R., Schemmer M., Seifried R., Shah N., Shah A., Shanbhag S., Sharma G., Skotnicki R., Sobczak M., Soman P., Sorrell V., Srichai M., Streeter J., Strickland L., Suliman S., Tebyanian N., Thomas D., Thompson R., Uretsky S., Vallurupalli S., Vandyck-Acquah M., Verma V., Villines T., Weinstein J., Wolinsky D., Zareba K., Zgaljardic M., Beretta M., Ferrando R., Kapitan M., Mut F., Djuraev O., Rozikhodjaeva G., Vera L., Duc B. D., Nguyen X. C., Hiep Nguyen P. M.

المساهمون: Einstein, A, Hirschfeld, C, Williams, M, Vitola, J, Better, N, Villines, T, Cerci, R, Shaw, L, Choi, A, Dorbala, S, Karthikeyan, G, Lu, B, Sinitsyn, V, Ansheles, A, Kudo, T, Bucciarelli-Ducci, C, Norgaard, B, Maurovich-Horvat, P, Campisi, R, Milan, E, Louw, L, Allam, A, Bhatia, M, Sewanan, L, Malkovskiy, E, Cohen, Y, Randazzo, M, Narula, J, Morozova, O, Pascual, T, Pynda, Y, Dondi, M, Paez, D, Hinterleitner, G, Lu, Y, Xu, Z, Erinne, I, Shetty, M, Lopez-Mattei, J, Parwani, P, Goda, A, Shirka, E, Bouyoucef, S, Chelghoum, L, Mansouri, F, Medjahedi, A, Naili, Q, Ridouh, M, Alasia, D, Alberghina, L, Aramayo, N, Buchara, D, Busso, F, Bustos Rivadero, J, Camilletti, J, Campanelli, H, Castro, R, Daicz, M, del Riego, H, Dragonetti, L, Echazarreta, D, Erriest, J, Faccio, F, Facello, A, Gallegos, H, Geronazzo, R, Glait, H, Hasbani, V, Jager, V, Lewkowicz, J, Lotti, J, Maciel, N, Masoli, O, Mastrovito, E, Medus, M, Merani, M, Molteni, S, Montecinos, M, Parisi, G, Sueldo, C, Perez de Arenaza, D, Quintana, L, Radzinschi, A, Redruello, M, Rodriguez, M, Rojas, H, Acuna, A, Schere, D, Traverso, S, Vazquez, G, Zeffiro, S, Sakanyan, M, Beuzeville, S, Boktor, R, Crowley, M, Downie, D, Dwivedi, G, Elison, B

مصطلحات موضوعية: cardiac testing, cardiovascular disease, coronaviru, COVID-19, global health

الوصف: Background: The extent to which health care systems have adapted to the COVID-19 pandemic to provide necessary cardiac diagnostic services is unknown. Objectives: The aim of this study was to determine the impact of the pandemic on cardiac testing practices, volumes and types of diagnostic services, and perceived psychological stress to health care providers worldwide. Methods: The International Atomic Energy Agency conducted a worldwide survey assessing alterations from baseline in cardiovascular diagnostic care at the pandemic's onset and 1 year later. Multivariable regression was used to determine factors associated with procedure volume recovery. Results: Surveys were submitted from 669 centers in 107 countries. Worldwide reduction in cardiac procedure volumes of 64% from March 2019 to April 2020 recovered by April 2021 in high- and upper middle-income countries (recovery rates of 108% and 99%) but remained depressed in lower middle- and low-income countries (46% and 30% recovery). Although stress testing was used 12% less frequently in 2021 than in 2019, coronary computed tomographic angiography was used 14% more, a trend also seen for other advanced cardiac imaging modalities (positron emission tomography and magnetic resonance; 22%-25% increases). Pandemic-related psychological stress was estimated to have affected nearly 40% of staff, impacting patient care at 78% of sites. In multivariable regression, only lower-income status and physicians’ psychological stress were significant in predicting recovery of cardiac testing. Conclusions: Cardiac diagnostic testing has yet to recover to prepandemic levels in lower-income countries. Worldwide, the decrease in standard stress testing is offset by greater use of advanced cardiac imaging modalities. Pandemic-related psychological stress among providers is widespread and associated with poor recovery of cardiac testing.

وصف الملف: STAMPA

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/35589162; info:eu-repo/semantics/altIdentifier/wos/WOS:000844180900005; volume:79; issue:20; firstpage:2001; lastpage:2017; numberofpages:17; journal:JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY; https://hdl.handle.net/10281/419558Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85129674907

الإتاحة: https://doi.org/10.1016/j.jacc.2022.03.348Test
https://hdl.handle.net/10281/419558Test

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3

دورية أكاديمية

Prognostic value of pericoronary adipose tissue and coronary vascular function by cardiac 82Rb PET/CT imaging in patients with suspected coronary artery disease and normal myocardial perfusion imaging

المؤلفون: Gaudieri, V, Zampella, E, Nappi, C, Assante, R, Mannarino, T, D"antonio, A, Giordano, A, Buongiorno, P, Petretta, M, Acampa, W, Arumugam, P, Cuocolo, A

المصدر: European Heart Journal - Cardiovascular Imaging ; volume 22, issue Supplement_1 ; ISSN 2047-2404 2047-2412

مصطلحات موضوعية: Cardiology and Cardiovascular Medicine, Radiology, Nuclear Medicine and imaging, General Medicine

الوصف: Funding Acknowledgements Type of funding sources: None. Introduction Pericoronary adipose tissue, due to its proximity to coronary arteries, has been proposed contribute to the progression of coronary atherosclerosis. Purpose The aim of this study was to evaluate the prognostic value of pericoronary fat thickness (PCFT), coronary artery calcium (CAC) score and myocardial perfusion reserve (MPR) by hybrid 82Rubidium (82Rb) PET/CT imaging in patients with suspected coronary artery disease (CAD) and normal myocardial perfusion imaging (MPI). Methods A total of 640 patients without overt CAD and with normal rest-stress 82Rb PET/CT MPI were studied. PCFT was calculated on CT images as the maximum fat thickness (mm) between heart surface and visceral epicardium surrounding the main coronary arteries. CAC score was categorized as 0, <400 or ≥400. MPR was considered reduced when <2. Endpoints events were cardiac death, nonfatal myocardial infarction and coronary revascularization. Results During a follow-up of 42 ± 13 months, 29 events occurred (cumulative event rate 5%). Patients with events were older (66 ± 13 vs. 60 ± 13 years, p < 0.01), had higher PCFT (13 ± 2 vs 11 ± 2 mm, p < 0.001), higher prevalence of CAC score ≥400 (48% vs. 21%, p < 0.01), and lower MPR (2.1 ± 0.7 vs. 2.7 ± 0.7, p < 0.001) compared to those without. A higher prevalence of MPR <2 was observed in patients with events (48% vs. 18, p < 0.001) compared to those without. Patients with reduced MPR had higher PCFT compared to those with normal MPR (12 ± 2 vs. 11 ± 1 mm, p < 0.01). A PCFT value of 11.2 mm was the best trade-off between sensitivity and specificity to detect a reduced MPR. Event rate was higher in patients above this threshold compared to those below (8% vs. 1.5%, p < 0.001). At Cox univariate analysis, age (p < 0.05), PCFT >11.2 mm (p < 0.001), CAC score ≥400 (p < 0.01), and MPR <2 (p < 0.001) were predictors of ...

الإتاحة: https://doi.org/10.1093/ehjci/jeaa356.354Test
http://academic.oup.com/ehjcimaging/article-pdf/22/Supplement_1/jeaa356.354/36214722/jeaa356.354.pdfTest

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4

دورية أكاديمية

Prognostic value of heart rate reserve in patients with suspected coronary artery disease undergoing stress myocardial perfusion imaging

المؤلفون: Nappi, C, Petretta, M, Cantoni, V, Green, R, Assante, R, Zampella, E, Gaudieri, V, Mannarino, T, D"antonio, A, Manganelli, M, Piscopo, L, Ponsiglione, A, Acampa, W, Cuocolo, A

المصدر: European Heart Journal - Cardiovascular Imaging ; volume 22, issue Supplement_3 ; ISSN 2047-2404 2047-2412

مصطلحات موضوعية: Cardiology and Cardiovascular Medicine, Radiology, Nuclear Medicine and imaging, General Medicine

الوصف: Funding Acknowledgements Type of funding sources: None. Background. The prognostic value of stress myocardial perfusion single-photon emission computed tomography (MPS) has been widely demonstrated. Also, chronotropic incompetence, evaluated by heart rate reserve (HRR) is associated with increased risk of adverse events. Yet, the incremental prognostic value of HRR over stress MPS data has not been fully investigated. Purpose. To assess the incremental prognostic value of HRR over stress MPS finding in patients with suspected coronary artery disease (CAD) undergoing exercise stress MPS. Methods. The study population consisted of 866 consecutive patients with suspected CAD undergoing exercise stress-MPS at University of Naples Federico II, between May 2002 and January 2014 as part of their diagnostic program. The primary study endpoint was all-cause mortality. All patients were followed for at least 60 months. HRR was calculated as the difference between peak exercise and resting HR, divided by the difference of age-predicted maximal and resting HR and expressed as percent. The summed difference score (SDS) was considered an index of ischemic burden. Patients were considered to have mild ischemia with a SDS of 2 to 6, and moderate-severe ischemia with a SDS ≥6. During follow-up, the occurrence of all-cause of deaths was noted and considered as event. Follow-up was censored at 84 months. Results. During follow-up, 61 deaths occurred, with a 7% cumulative event rate. Patients experiencing death were older (56.2 ± 10.7 years vs. 66.4 ± 8.6 years), with a higher prevalence of male gender (56% vs. 87 %, P < 0.05) and diabetes mellitus (23% vs. 36%, P < 0.05). At stress-MPS, patients with event had lower mean values of HRR (53.2 ± 21.3% vs. 61.5 ± 16.4%, P < 0.0001) and higher prevalence of moderate-severe ischemia (24% vs. 8%, P < 0.0001). The best trade-off between sensitivity and specificity for identifying chronotropic incompetence was a HRR <67% with an area under the ...

الإتاحة: https://doi.org/10.1093/ehjci/jeab111.037Test
http://academic.oup.com/ehjcimaging/article-pdf/22/Supplement_3/jeab111.037/39199380/jeab111.037.pdfTest

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5

دورية أكاديمية

Use of coronary artery calcium scanning as a triage for invasive coronary angiography

المؤلفون: Assante R., Klain M., Acampa W.

المساهمون: Assante, R., Klain, M., Acampa, W.

مصطلحات موضوعية: Calcium, Coronary Angiography, Coronary Vessel, Human, Referral and Consultation, Tomography, Emission-Computed, Single-Photon, Coronary Artery Disease, Triage

العلاقة: info:eu-repo/semantics/altIdentifier/wos/WOS:000462203700039; volume:26; issue:2; firstpage:613; lastpage:615; numberofpages:3; journal:JOURNAL OF NUCLEAR CARDIOLOGY; http://hdl.handle.net/11588/840587Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85031904208

الإتاحة: https://doi.org/10.1007/s12350-017-1076-8Test
http://hdl.handle.net/11588/840587Test

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6

دورية أكاديمية

Computed tomography and nuclear medicine for the assessment of coronary inflammation: clinical applications and perspectives

المؤلفون: Guaricci A. I., Neglia D., Acampa W., Andreini D., Baggiano A., Bianco F., Carrabba N., Conte E., Gaudieri V., Mushtaq S., Napoli G., Pergola V., Pontone G., Pedrinelli R., Mercuro G., Indolfi C., Guglielmo M.

المساهمون: A.I. Guaricci, D. Neglia, W. Acampa, D. Andreini, A. Baggiano, F. Bianco, N. Carrabba, E. Conte, V. Gaudieri, S. Mushtaq, G. Napoli, V. Pergola, G. Pontone, R. Pedrinelli, G. Mercuro, C. Indolfi, M. Guglielmo

مصطلحات موضوعية: 18F-FDG PET, coronary artery disease, coronary computed tomography angiography, epicardial adipose tissue, pericoronary adipose tissue, Settore MED/11 - Malattie dell'Apparato Cardiovascolare

الوصف: There is increasing evidence that in patients with atherosclerotic cardiovascular disease (ASCVD) under optimal medical therapy, a persisting dysregulation of the lipid and glucose metabolism, associated with adipose tissue dysfunction and inflammation, predicts a substantial residual risk of disease progression and cardiovascular events. Despite the inflammatory nature of ASCVD, circulating biomarkers such as high-sensitivity C-reactive protein and interleukins may lack specificity for vascular inflammation. As known, dysfunctional epicardial adipose tissue (EAT) and pericoronary adipose tissue (PCAT) produce pro-inflammatory mediators and promote cellular tissue infiltration triggering further pro-inflammatory mechanisms. The consequent tissue modifications determine the attenuation of PCAT as assessed and measured by coronary computed tomography angiography (CCTA). Recently, relevant studies have demonstrated a correlation between EAT and PCAT and obstructive coronary artery disease, inflammatory plaque status and coronary flow reserve (CFR). In parallel, CFR is well recognized as a marker of coronary vasomotor function that incorporates the haemodynamic effects of epicardial, diffuse and small-vessel disease on myocardial tissue perfusion. An inverse relationship between EAT volume and coronary vascular function and the association of PCAT attenuation and impaired CFR have already been reported. Moreover, many studies demonstrated that 18F-FDG PET is able to detect PCAT inflammation in patients with coronary atherosclerosis. Importantly, the perivascular FAI (fat attenuation index) showed incremental value for the prediction of adverse clinical events beyond traditional risk factors and CCTA indices by providing a quantitative measure of coronary inflammation. As an indicator of increased cardiac mortality, it could guide early targeted primary prevention in a wide spectrum of patients. In this review, we summarize the current evidence regarding the clinical applications and perspectives of EAT and PCAT ...

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/37052223; info:eu-repo/semantics/altIdentifier/wos/WOS:000992168300008; volume:24; issue:Suppl. 1; firstpage:E67; lastpage:E76; numberofpages:10; journal:JOURNAL OF CARDIOVASCULAR MEDICINE; https://hdl.handle.net/2434/1001782Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85152305862

الإتاحة: https://doi.org/10.2459/JCM.0000000000001433Test
https://hdl.handle.net/2434/1001782Test

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