المؤلفون: Boaro, Alessandro, Mahadik, Bhargavi, Petrillo, Anthony, Siddi, Francesca, Devi, Sharmila, Chawla, Shreya, Abunimer, Abdullah M, Feletti, Alberto, Fiorindi, Alessandro, Longatti, Pierluigi, Sala, Francesco, Smith, Timothy R, Mekary, Rania A

المساهمون: Boaro, Alessandro, Mahadik, Bhargavi, Petrillo, Anthony, Siddi, Francesca, Devi, Sharmila, Chawla, Shreya, Abunimer, Abdullah M, Feletti, Alberto, Fiorindi, Alessandro, Longatti, Pierluigi, Sala, Francesco, Smith, Timothy R, Mekary, Rania A

مصطلحات موضوعية: complications, efficacy, endoscopic third ventriculostomy, flexible neuroendoscopy, hydrocephalus, rigid neuroendoscopy

الوصف: Endoscopic third ventriculostomy (ETV) is a well-established surgical procedure for hydrocephalus treatment, but there is sparse evidence on the optimal choice between flexible and rigid approaches. A meta-analysis was conducted to compare efficacy and safety profiles of both techniques in pediatrics and adults. A comprehensive search was conducted on PubMED, EMBASE, and Cochrane until 11/10/2019. Efficacy was evaluated comparing incidence of ETV failure, while safety was defined by the incidence of perioperative complications, intraoperative bleedings, and deaths. Random-effects models were used to pool the incidence. Out of 1365 studies, 46 case series were meta-analyzed, yielding 821 patients who underwent flexible ETV and 2918 who underwent rigid ETV, with an age range of [5days-87years]. Although flexible ETV had a higher incidence of failure in adults (flexible: 54%, 95%CI: 22-82% vs rigid: 20%, 95%CI: 22-82%) possibly due to confounding due to etiology in adults treated with flexible, a smaller difference was seen in pediatrics (flexible: 36%, pediatric: 32%). Safety profiles were acceptable for both techniques, with a certain degree of variability for complications (flexible 2%, rigid 18%) and death (flexible 1%, rigid 3%) in pediatrics as well as complications (rigid 9%, flexible 13%), death (flexible 4%, rigid 6%) and intra-operative bleeding events (rigid 6%, flexible 8%) in adults. No clear superiority in efficacy could be depicted between flexible and rigid ETV for hydrocephalus treatment. Safety profiles varied by age but were acceptable for both techniques. Well-designed comparative studies are needed to assess the optimal endoscopic treatment option for hydrocephalus.

وصف الملف: STAMPA

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34173114; info:eu-repo/semantics/altIdentifier/wos/WOS:000666999500002; volume:45; issue:1; firstpage:199; lastpage:216; numberofpages:18; journal:NEUROSURGICAL REVIEW; http://hdl.handle.net/11562/1045423Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85108827259; https://doi.org/10.1007/s10143-021-01590-6Test

الإتاحة: https://doi.org/10.1007/s10143-021-01590-6Test
http://hdl.handle.net/11562/1045423Test

المؤلفون: Ben-Shlomo, Nir, Rahimi, Amina, Abunimer, Abdullah M., Guenette, Jeffrey P., Juliano, Amy F., Starr, Jacqueline R., Jayender, Jagadeesan, Corrales, C. Eduardo

المصدر: Otology & Neurotology ; volume 45, issue 3, page 311-318 ; ISSN 1537-4505 1531-7129

الوصف: Objective To assess the rate of iatrogenic injury to the inner ear in vestibular schwannoma resections. Study Design Retrospective case review Setting Multiple academic tertiary care hospitals. Patients Patients who underwent retrosigmoid or middle cranial fossa approaches for vestibular schwannoma resection between 1993 and 2015. Intervention Diagnostic with therapeutic implications. Main Outcome Measure Drilling breach of the inner ear as confirmed by operative note or postoperative computed tomography (CT). Results 21.5% of patients undergoing either retrosigmoid or middle fossa approaches to the internal auditory canal were identified with a breach of the vestibulocochlear system. Because of the lack of postoperative CT imaging in this cohort, this is likely an underestimation of the true incidence of inner ear breaches. Of all postoperative CT scans reviewed, 51.8% had an inner ear breach. As there may be bias in patients undergoing postoperative CT, a middle figure based on sensitivity analyses estimates the incidence of inner ear breaches from lateral skull base surgery to be 34.7%. CONCLUSIONS A high percentage of vestibular schwannoma surgeries via retrosigmoid and middle cranial fossa approaches result in drilling breaches of the inner ear. This study reinforces the value of preoperative image analysis for determining risk of inner ear breaches during vestibular schwannoma surgery and the importance of acquiring CT studies postoperatively to evaluate the integrity of the inner ear.

الإتاحة: https://doi.org/10.1097/mao.0000000000004105Test

المؤلفون: Alborno, Yahya, Abunimer, Abdullah M., Abuodeh, Yousef, Salameh, Motasem, Kayali, Hammam, Ahmed, Ghalib

المصدر: European Journal of Orthopaedic Surgery & Traumatology ; volume 33, issue 5, page 1619-1619 ; ISSN 1432-1068

مصطلحات موضوعية: Orthopedics and Sports Medicine, Surgery

الإتاحة: https://doi.org/10.1007/s00590-022-03411-yTest

المؤلفون: Boaro, Alessandro, Mahadik, Bhargavi, Petrillo, Anthony, Siddi, Francesca, Devi, Sharmila, Chawla, Shreya, Abunimer, Abdullah M., Feletti, Alberto, Fiorindi, Alessandro, Longatti, Pierluigi, Sala, Francesco, Smith, Timothy R., Mekary, Rania A.

المساهمون: Università degli Studi di Verona

المصدر: Neurosurgical Review ; volume 45, issue 1, page 199-216 ; ISSN 0344-5607 1437-2320

مصطلحات موضوعية: Neurology (clinical), General Medicine, Surgery

الوصف: Endoscopic third ventriculostomy (ETV) is a well-established surgical procedure for hydrocephalus treatment, but there is sparse evidence on the optimal choice between flexible and rigid approaches. A meta-analysis was conducted to compare efficacy and safety profiles of both techniques in pediatrics and adults. A comprehensive search was conducted on PubMED, EMBASE, and Cochrane until 11/10/2019. Efficacy was evaluated comparing incidence of ETV failure, while safety was defined by the incidence of perioperative complications, intraoperative bleedings, and deaths. Random-effects models were used to pool the incidence. Out of 1365 studies, 46 case series were meta-analyzed, yielding 821 patients who underwent flexible ETV and 2918 who underwent rigid ETV, with an age range of [5 days–87 years]. Although flexible ETV had a higher incidence of failure in adults (flexible: 54%, 95%CI: 22–82% vs rigid: 20%, 95%CI: 22–82%) possibly due to confounding due to etiology in adults treated with flexible, a smaller difference was seen in pediatrics (flexible: 36%, pediatric: 32%). Safety profiles were acceptable for both techniques, with a certain degree of variability for complications (flexible 2%, rigid 18%) and death (flexible 1%, rigid 3%) in pediatrics as well as complications (rigid 9%, flexible 13%), death (flexible 4%, rigid 6%) and intra-operative bleeding events (rigid 6%, flexible 8%) in adults. No clear superiority in efficacy could be depicted between flexible and rigid ETV for hydrocephalus treatment. Safety profiles varied by age but were acceptable for both techniques. Well-designed comparative studies are needed to assess the optimal endoscopic treatment option for hydrocephalus.

الإتاحة: https://doi.org/10.1007/s10143-021-01590-6Test

المؤلفون: Abou-Al-Shaar, Hussam, Krisht, Khaled M., Cohen, Michael A., Abunimer, Abdullah M., Neil, Jayson A., Karsy, Michael, Alzhrani, Gmaan, Couldwell, William T.

المصدر: Frontiers in Surgery ; volume 7 ; ISSN 2296-875X

الإتاحة: https://doi.org/10.3389/fsurg.2020.00001Test

المؤلفون: Abunimer, Abdullah M., Hammoudeh, Lubna, Dee, Edward Christopher, Lak, Asad M., Chi, John, Lu, Yi, Groff, Michael, Shin, John H., Lam, Miranda B., Zaidi, Hasan A.

المصدر: European Spine Journal ; volume 32, issue 3, page 994-1002 ; ISSN 0940-6719 1432-0932

مصطلحات موضوعية: Orthopedics and Sports Medicine, Surgery

الإتاحة: https://doi.org/10.1007/s00586-022-07505-3Test

المؤلفون: Almekkawi, Ahmad Kareem, El Ahmadieh, Tarek Y, Wu, Eva M, Abunimer, Abdullah M, Abi-Aad, Karl R, Aoun, Salah G, Plitt, Aaron R, El Tecle, Najib E, Patel, Toral, Stummer, Walter, Bendok, Bernard R

المصدر: Operative Neurosurgery ; volume 19, issue 1, page 1-8 ; ISSN 2332-4252 2332-4260

الوصف: BACKGROUND For optimizing high-grade glioma resection, 5-aminolevulinic acid is a reliable tool. However, its efficacy in low-grade glioma resection remains unclear. OBJECTIVE To study the role of 5-aminolevulinic acid in low-grade glioma resection and assess positive fluorescence rates and the effect on the extent of resection. METHODS A systematic review of PubMed, Google Scholar, and Cochrane was performed from the date of inception to February 1, 2019. Studies that correlated 5-aminolevulinic acid fluorescence with low-grade glioma in the setting of operative resection were selected. Studies with biopsy only were excluded. Positive fluorescence rates were calculated. The quality index of the selected papers was provided. No patient information was used, so Institutional Review Board approval and patient consent were not required. RESULTS A total of 12 articles met the selection criteria with 244 histologically confirmed low-grade glioma patients who underwent microsurgical resection. All patients received 20 mg/kg body weight of 5-aminolevulinic acid. Only 60 patients (n = 60/244; 24.5%) demonstrated visual intraoperative 5-aminolevulinic acid fluorescence. The extent of resection was reported in 4 studies; however, the data combined low- and high-grade tumors. Only 2 studies reported on tumor location. Only 3 studies reported on clinical outcomes. The Zeiss OPMI Pentero microscope was most commonly used across all studies. The average quality index was 14.58 (range: 10-17), which correlated with an overall good quality. CONCLUSION There is an overall low correlation between 5-aminolevulinic acid fluorescence and low-grade glioma. Advances in visualization technology and using standardized fluorescence quantification methods may further improve the visualization and reliability of 5-aminolevulinic acid fluorescence in low-grade glioma resection.

الإتاحة: https://doi.org/10.1093/ons/opz336Test
http://academic.oup.com/ons/article-pdf/19/1/1/33348192/opz336.pdfTest

المؤلفون: Lak, Asad Mehmood, Abunimer, Abdullah M, Rahimi, Amina, Tafel, Ian, Zaidi, Hasan Aqdas

المصدر: Neurosurgery ; volume 66, issue Supplement 1, page 310-820 ; ISSN 0148-396X

الإتاحة: https://doi.org/10.1093/neuros/nyz310_820Test

المؤلفون: Aboulebda, Mohanad, Salman, Loay A., Hammad, Mohammad, Foodool, Mazin A., Kong, Geraldine, Abunimer, Abdullah M., Abu Hejleh, Hasan A., Ahmedq, Ghalib

المصدر: Journal of Musculoskeletal Surgery & Research (JMSR); Jul-Sep2023, Vol. 7 Issue 3, p164-169, 6p

المؤلفون: Abou-Al-Shaar, Hussam, Abunimer, Abdullah M., White, Timothy G., Dehdashti, Amir R.

المصدر: Acta Neurochirurgica ; volume 161, issue 1, page 85-86 ; ISSN 0001-6268 0942-0940

مصطلحات موضوعية: Neurology (clinical), Surgery

الإتاحة: https://doi.org/10.1007/s00701-018-3741-3Test