المؤلفون: Khumpirapang, Nattakanwadee, Suknuntha, Krit, Wongrattanakamon, Pathomwat, Jiranusornkul, Supat, Anuchapreeda, Songyot, Wellendorph, Petrine, Mullertz, Anette, Rades, Thomas, Okonogi, Siriporn

المصدر: Khumpirapang , N , Suknuntha , K , Wongrattanakamon , P , Jiranusornkul , S , Anuchapreeda , S , Wellendorph , P , Mullertz , A , Rades , T & Okonogi , S 2022 , ' The Binding of Alpinia galanga Oil and Its Nanoemulsion to Mammal GABA(A) Receptors Using Rat Cortical Membranes and an In Silico Modeling Platform ' , Pharmaceutics , vol. 14 , no. 3 , 650 . https://doi.org/10.3390/pharmaceutics14030650Test

مصطلحات موضوعية: Alpinia galanga, essential oil, mammal anesthesia, anesthetic pathway, positive allosteric modulation, binding assay, CLOVE OIL, METHYLEUGENOL, ANTIOXIDANT, 1,8-CINEOLE, MODULATION, ADSORPTION, EXTRACTS, RHIZOMES, CURRENTS, GLYCINE

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.3390/pharmaceutics14030650Test
https://curis.ku.dk/portal/da/publications/the-binding-of-alpinia-galanga-oil-and-its-nanoemulsion-to-mammal-gabaa-receptors-using-rat-cortical-membranes-and-an-in-silico-modeling-platformTest(e76170a8-ff3b-428e-9ee2-5e66cd2bb884).html
https://curis.ku.dk/ws/files/305180817/pharmaceutics_14_00650.pdfTest

المؤلفون: Kaleeckal G. Harikumar, Thomas Coudrat, Aditya J. Desai, Maoqing Dong, Daniela G. Dengler, Sebastian G. B. Furness, Arthur Christopoulos, Denise Wootten, Eduard A. Sergienko, Patrick M. Sexton, Laurence J. Miller

المصدر: Frontiers in Endocrinology, Vol 12 (2021)

مصطلحات موضوعية: cholecystokinin, cholecystokinin receptor, allosteric modulation, cholesterol, obesity, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fendo.2021.789957/fullTest; https://doaj.org/toc/1664-2392Test

الوصول الحر: https://doaj.org/article/895703c860ab400c964a97eea810e55bTest

المؤلفون: Zachary J. Frangos, Ryan P. Cantwell Chater, Robert J. Vandenberg

المصدر: Frontiers in Molecular Biosciences, Vol 8 (2021)

مصطلحات موضوعية: glycine transporter, allosteric modulation, solute carrier 6 (SLC6), neurotransmitter sodium symporters (NSS), lipid modulation, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fmolb.2021.734427/fullTest; https://doaj.org/toc/2296-889XTest

الوصول الحر: https://doaj.org/article/59be87d5f5c9496f8c74f204583d012aTest

المؤلفون: Braulio Muñoz, Trinidad Mariqueo, Pablo Murath, Christian Peters, Gonzalo E. Yevenes, Gustavo Moraga-Cid, Robert W. Peoples, Luis G. Aguayo

المصدر: Frontiers in Molecular Neuroscience, Vol 14 (2021)

مصطلحات موضوعية: receptor pharmacology, glycine receptor, ethanol, allosteric modulation, G-protein, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fnmol.2021.763868/fullTest; https://doaj.org/toc/1662-5099Test

الوصول الحر: https://doaj.org/article/a1e12b7b340445f3965359c8b8f2cef4Test

المؤلفون: Bergh, Cathrine, Heusser, Stephanie A., Howard, Rebecca J., Lindahl, Erik, 1972

المصدر: eLIFE. 10

مصطلحات موضوعية: ligand-gated ion channel, gating, allosteric modulation, molecular dynamics, electrophysiology, markov state model, Xenopus

وصف الملف: print

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-200936Test
https://doi.org/10.7554/eLife.68369Test

المؤلفون: Leach, Katie, Gregory, Karen J, Kufareva, Irina, Khajehali, Elham, Cook, Anna E, Abagyan, Ruben, Conigrave, Arthur D, Sexton, Patrick M, Christopoulos, Arthur

المصدر: Cell Research. 26(5)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, 1.1 Normal biological development and functioning, Underpinning research, Allosteric Regulation, Amines, Amino Acid Sequence, Amino Acids, Binding Sites, Calcium, HEK293 Cells, Humans, Mutation, Pharmaceutical Preparations, Receptors, Calcium-Sensing, Signal Transduction, Structure-Activity Relationship, allosteric modulation, drug discovery, G protein-coupled receptor, molecular modeling, mutagenesis, structural biology, Clinical Sciences, Developmental Biology, Biochemistry and cell biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/0q05v2mcTest

المؤلفون: Li Z, Li J, Liu L, Deng W, Liu Q, Liu R, Zhang W, He Z, Fan L, Yang Y, Duan Y, Hou H, Wang X, Yang Z, Chen S, Wang Y, Huang N, Chen J

المصدر: Drug Design, Development and Therapy, Vol Volume 14, Pp 2585-2594 (2020)

مصطلحات موضوعية: alpha2-adrenoceptor, selectivity, linker length, allosteric modulation, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: https://www.dovepress.com/structural-insight-into-the-mechanism-of-4-aminoquinolines-selectivity-peer-reviewed-article-DDDTTest; https://doaj.org/toc/1177-8881Test

الوصول الحر: https://doaj.org/article/92b41eef8b6e478ea886a8a76adf9091Test

المؤلفون: Wei-Ven Tee, Enrico Guarnera, Igor N. Berezovsky

المصدر: Current Research in Structural Biology, Vol 2, Iss , Pp 191-203 (2020)

مصطلحات موضوعية: Protein allostery, Protein intrinsic disorder, Order-disorder transitions, Allosteric modulation, Allosteric free energy, Allosteric control scale, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2665928X20300192Test; https://doaj.org/toc/2665-928XTest

الوصول الحر: https://doaj.org/article/51630aabf736437d861b835a44d1cb4fTest

المؤلفون: Xiaoyan Wang (8433), Dongsheng Liu (73360), Ling Shen (86009), Fahui Li (6306830), Yongze Li (433770), Lingyun Yang (2291101), Tiandan Xu (11512319), Houchao Tao (1915252), Deqiang Yao (11512322), Lijie Wu (340022), Kunio Hirata (480519), Laura M. Bohn (503155), Alexandros Makriyannis (32548), Xiaohong Liu (50816), Tian Hua (799051), Zhi-Jie Liu (33474), Jiangyun Wang (1421851)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Biotechnology, Inorganic Chemistry, Infectious Diseases, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, unnatural amino acid, uncovering conformational states, ray crystallography methods, previously unrecognized pre, phenyl ­ alanine, gpcr allosteric modulation, genetically encoded probes, explain org27569 ’, cannabinoid receptor 1, baculovirus expression system, allosteric modulator org27569, allosteric modulation model, agonists synergistically stabilize, environmentally sensitive site, allosteric modulation mechanism, 19 , f nmr ), f nmr, mtff ), target protein, powerful tool

العلاقة: https://figshare.com/articles/journal_contribution/A_Genetically_Encoded_F_19_NMR_Probe_Reveals_the_Allosteric_Modulation_Mechanism_of_Cannabinoid_Receptor_1/16722791Test

الإتاحة: https://doi.org/10.1021/jacs.1c06847.s001Test

المؤلفون: Cathrine Bergh, Stephanie A Heusser, Rebecca Howard, Erik Lindahl

المصدر: eLife, Vol 10 (2021)

مصطلحات موضوعية: ligand-gated ion channel, gating, allosteric modulation, molecular dynamics, electrophysiology, markov state model, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://elifesciences.org/articles/68369Test; https://doaj.org/toc/2050-084XTest

الوصول الحر: https://doaj.org/article/8d7ef17dfa724cc3afa78e5417a615beTest