المؤلفون: Marc Heidl, Remo Campiche, Stéphanie Boudon, Eileen Jackson, Anna Vuorinen, Eliane Ursula Wandeler, Alex Odermatt

المصدر: Bioorganic & Medicinal Chemistry. 26:5128-5139

مصطلحات موضوعية: Keratinocytes, Models, Molecular, 0301 basic medicine, Molecular model, Clinical Biochemistry, Pharmaceutical Science, Peptide, Biochemistry, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Drug Discovery, medicine, Humans, Structure–activity relationship, Enzyme Inhibitors, Molecular Biology, IC50, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, Organic Chemistry, 030104 developmental biology, medicine.anatomical_structure, Enzyme, chemistry, Design synthesis, Drug Design, 030220 oncology & carcinogenesis, Molecular Medicine, Cortisone, Peptides, Keratinocyte, hormones, hormone substitutes, and hormone antagonists, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44589089e65dd27c387a1b6f9f5fc8f0Test
https://doi.org/10.1016/j.bmc.2018.09.009Test

المؤلفون: Hannah Forde, Norman F. Taylor, William Drake, Diarmuid Smith, Lucy Ann Behan, Christopher J. Thompson, Amar Agha, John P. Monson

المصدر: Endocrine Practice. 24:875-881

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Hydrocortisone, Hormone Replacement Therapy, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Hypopituitarism, Craniopharyngioma, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, 11β-hydroxysteroid dehydrogenase type 1, Internal medicine, 11-beta-Hydroxysteroid Dehydrogenase Type 1, medicine, Humans, Pituitary Neoplasms, Prolactinoma, Tetrahydrocortisone, Pituitary ACTH Hypersecretion, Growth Disorders, biology, Human Growth Hormone, business.industry, Tetrahydrocortisol, General Medicine, Middle Aged, medicine.disease, Cushing Disease, Cortisone, chemistry, Case-Control Studies, 030220 oncology & carcinogenesis, biology.protein, Female, business, hormones, hormone substitutes, and hormone antagonists, medicine.drug, Hormone

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f774bc5b93c2e330a83e5f04234ec081Test
https://doi.org/10.4158/ep-2018-0154Test

المؤلفون: Xianwu Chen, Xiaoheng Li, Lubin Xie, Ren-Shan Ge, Huitao Li, Yiyan Wang, Linchao Li, Baiping Mao, Tiantian Song, Qingquan Lian, Jianpeng Liu, Lanlan Chen

المصدر: Molecular and Cellular Endocrinology. 472:26-39

مصطلحات موضوعية: Male, 0301 basic medicine, endocrine system, medicine.medical_specialty, Down-Regulation, Cell Count, Biochemistry, Proinflammatory cytokine, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Internal medicine, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Cytokine Receptor gp130, medicine, Animals, Cell Lineage, Testosterone, STAT3, Molecular Biology, Interleukin 4, Cell Proliferation, Interleukin 3, Leydig cell, biology, Interleukin-6, Chemistry, Stem Cells, Leydig Cells, Interleukin, Cell Differentiation, Rats, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, biology.protein, Thy-1 Antigens, Signal transduction, Luteinizing hormone

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95ddb599dbf364b648178fa873e7865eTest
https://doi.org/10.1016/j.mce.2017.11.016Test

المؤلفون: Ki-Ho Chang, Soon Kil Ahn, Sung Pyo Hong, Dongoh Han

المصدر: European Journal of Pharmacology. 835:169-178

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, medicine.medical_specialty, Protein Conformation, Adipose tissue, Adamantane, 030209 endocrinology & metabolism, Mice, 03 medical and health sciences, 0302 clinical medicine, 11β-hydroxysteroid dehydrogenase type 1, Oral administration, 3T3-L1 Cells, Internal medicine, 11-beta-Hydroxysteroid Dehydrogenase Type 1, medicine, Animals, Humans, Enzyme Inhibitors, Pharmacology, biology, Chemistry, Body Weight, medicine.disease, In vitro, Rats, 030104 developmental biology, Endocrinology, Knockout mouse, biology.protein, Metabolic syndrome, hormones, hormone substitutes, and hormone antagonists, Glucocorticoid, Ex vivo, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd7b247f950f88af8b906bc4ded22b4bTest
https://doi.org/10.1016/j.ejphar.2018.08.005Test

المؤلفون: Antje R. Weseler, Aalt Bast, Gesiele Veríssimo

المساهمون: Promovendi NTM, Farmacologie en Toxicologie, RS: NUTRIM - R3 - Respiratory & Age-related Health, RS: FSE UCV Adaptive responses in relation to health effect and safety of nutrition

المصدر: Chemico-Biological Interactions, 291, 237-244. Elsevier Ireland Ltd

مصطلحات موضوعية: 0301 basic medicine, Time Factors, Flavonols, LUNG EPITHELIAL-CELLS, NF-KAPPA-B, Anti-Inflammatory Agents, Toxicology, medicine.disease_cause, Antioxidants, Cortisol, TERT-BUTYL HYDROPEROXIDE, HISTONE DEACETYLASE 2, 0302 clinical medicine, tert-Butylhydroperoxide, 11-beta-Hydroxysteroid Dehydrogenase Type 1, OXIDATIVE STRESS, Chemistry, Histone deacetylase 2, Interleukin, General Medicine, Oxidants, Cell biology, CORTICOSTEROID RESISTANCE, 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE-1, 030220 oncology & carcinogenesis, medicine.symptom, hormones, hormone substitutes, and hormone antagonists, Glucocorticoid, medicine.drug, LOCAL AMPLIFICATION, Cell Survival, Inflammation, OBSTRUCTIVE PULMONARY-DISEASE, Histone Deacetylases, Cell Line, 03 medical and health sciences, Immune system, medicine, Humans, Glucocorticoids, Flavonoids, Tumor Necrosis Factor-alpha, Macrophages, fungi, Interleukin-8, GRAPE SEED EXTRACT, NFKB1, 030104 developmental biology, Gene Expression Regulation, Cortisone, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b51e7b5c5cc440aee3d2fe9eec36296Test
https://doi.org/10.1016/j.cbi.2018.06.024Test

المؤلفون: Valentina Di Liberto, Ali Rezaei, Heidrun Potschka, Nina Miljanovic, R. Maarten van Dijk, Stefanie M. Hauck

المساهمون: Miljanovic, Nina, Hauck, Stefanie M., van Dijk, R. Maarten, Di Liberto, Valentina, Rezaei, Ali, Potschka, Heidrun

المصدر: Neurobiol. Dis. 157:105423 (2021)
Neurobiology of Disease, Vol 157, Iss, Pp 105423-(2021)

مصطلحات موضوعية: Male, Proteomics, 0301 basic medicine, Proteome, Hippocampus, Epilepsies, Myoclonic, Haploinsufficiency, Scn1a, Synaptic Transmission, Elevated Plus Maze Test, Epilepsy, Mice, 0302 clinical medicine, Tandem Mass Spectrometry, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Genetic epilepsy, Carbon-Nitrogen Ligases, Gene Knock-In Techniques, Gliosis, Neuronal Plasticity, Behavior, Animal, Epileptic encephalopathy, Immunohistochemistry, Astrogliosis, Neurology, Disease Progression, Female, Signal Transduction, RC321-571, Dopamine and cAMP-Regulated Phosphoprotein 32, Neovascularization, Physiologic, Neurosciences. Biological psychiatry. Neuropsychiatry, Biology, Nitric Oxide, 03 medical and health sciences, Dravet syndrome, medicine, Animals, Hyperthermia, Social Behavior, ras-GRF1, Proteomic Profiling, medicine.disease, Vascular Endothelial Growth Factor Receptor-2, NAV1.1 Voltage-Gated Sodium Channel, Disease Models, Animal, 030104 developmental biology, Rotarod Performance Test, Synaptic plasticity, Epileptic Encephalopathy, Genetic Epilepsy, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Open Field Test, Neuroscience, 030217 neurology & neurosurgery, Chromatography, Liquid

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a83b87483ab00ea1c173931eabe59222Test
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=62322Test

المؤلفون: Shanshan Li, Jinyan Cai, Jingjing Zhang, Jiao Guo, Xue Xiao, Yanduan Lin

المصدر: Biomedicine & Pharmacotherapy, Vol 133, Iss, Pp 111060-(2021)

مصطلحات موضوعية: Blood Glucose, Male, 0301 basic medicine, medicine.medical_specialty, Corticotropin-Releasing Hormone, Fingerprint, FTZ, Adipose tissue, Blood lipids, RM1-950, Mass Spectrometry, Streptozocin, Diabetes Mellitus, Experimental, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Insulin resistance, Diabetes mellitus, Adrenocorticotropic Hormone, Internal medicine, 11-beta-Hydroxysteroid Dehydrogenase Type 1, medicine, Animals, Hypoglycemic Agents, 11β-HSD1, Chromatography, High Pressure Liquid, Hypolipidemic Agents, Pharmacology, Chemistry, fungi, General Medicine, medicine.disease, Streptozotocin, Lipids, Metabolism disorder, 030104 developmental biology, Endocrinology, Compositions, 030220 oncology & carcinogenesis, Adipose triglyceride lipase, Therapeutics. Pharmacology, Insulin Resistance, Corticosterone, Biomarkers, hormones, hormone substitutes, and hormone antagonists, Drugs, Chinese Herbal, Hormone, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da34b6fc42fe76de11c06d03baad287aTest
http://www.sciencedirect.com/science/article/pii/S075333222031252XTest

المؤلفون: Hyo Hyun Seo, Myeong Sam Park, Seoyeon Kyung, Seunghyun Kang, Jeong Su-Gyeong, Seok Kyun Yun, Sang Hyun Moh, Abadie Sophie, Hyeonju Yeo, Kyung-Eun Lee

المصدر: International Journal of Molecular Sciences
Volume 21
Issue 22
International Journal of Molecular Sciences, Vol 21, Iss 8439, p 8439 (2020)

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, collagen, Protein Conformation, Gene Expression, Stimulation, Human skin, Skin Aging, Tissue Culture Techniques, lcsh:Chemistry, 030207 dermatology & venereal diseases, 0302 clinical medicine, Kisspeptin, Skin Physiological Phenomena, 11-beta-Hydroxysteroid Dehydrogenase Type 1, 11β-HSD1, lcsh:QH301-705.5, Spectroscopy, Skin, Kisspeptins, Molecular Structure, integumentary system, MMP-1, Biological activity, General Medicine, Computer Science Applications, Cell biology, Matrix Metalloproteinase 1, hormones, hormone substitutes, and hormone antagonists, Ultraviolet Rays, Neuropeptide, Biology, Models, Biological, Catalysis, Article, Collagen Type I, Kisspeptin-mimicking fragments, Cell Line, Inorganic Chemistry, 03 medical and health sciences, Humans, Secretion, RNA, Messenger, Physical and Theoretical Chemistry, Molecular Biology, skin aging, Solid-Phase Synthesis Techniques, Interleukin-6, Organic Chemistry, Interleukin-8, Molecular Mimicry, Fibroblasts, Peptide Fragments, 030104 developmental biology, lcsh:Biology (General), lcsh:QD1-999, Hormone

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a23a9a7d7e3526a42f7f35977c8f1840Test

المؤلفون: Chen, Jingfei, Mishra, Ritu, Yu, Yaqin, McDonald, Jeffrey G., Eckert, Kaitlyn M., Gao, Lu, Mendelson, Carole R.

المصدر: FASEB J

مصطلحات موضوعية: Male, Mice, Knockout, Tumor Necrosis Factor-alpha, CCAAT-Enhancer-Binding Protein-beta, Epithelial Cells, Article, Mice, Fetus, Receptors, Glucocorticoid, 11-beta-Hydroxysteroid Dehydrogenase Type 1, CCAAT-Enhancer-Binding Protein-alpha, CCAAT-Enhancer-Binding Proteins, Animals, Cytokines, Female, RNA, Messenger, Glucocorticoids, Lung, hormones, hormone substitutes, and hormone antagonists, Protein Binding, Signal Transduction, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::b3ee6503189a4e888281fd49fd07be7fTest
https://europepmc.org/articles/PMC7713510Test/

المؤلفون: Kang Sun, Yuan Wang, Shuanggang Hu, Hanting Zhao, Qinling Zhu, Yanzhi Du, Zhenyi Zhu, Xinyu Li, Rui Xu, Jiaxing Li, Jufang Yao, Ying Ding, Guangxin Yao, Jia Qi, Yun Sun

المصدر: Metabolism: clinical and experimental. 119

مصطلحات موضوعية: 0301 basic medicine, endocrine system, medicine.medical_specialty, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Drug Evaluation, Preclinical, Dehydroepiandrosterone, 030209 endocrinology & metabolism, Ovary, Piperazines, Anovulation, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Insulin resistance, 11β-hydroxysteroid dehydrogenase type 1, Internal medicine, 11-beta-Hydroxysteroid Dehydrogenase Type 1, medicine, Animals, Humans, Enzyme Inhibitors, Cells, Cultured, Estrous cycle, Sulfonamides, biology, business.industry, nutritional and metabolic diseases, medicine.disease, Polycystic ovary, female genital diseases and pregnancy complications, Rats, Disease Models, Animal, Thiazoles, 030104 developmental biology, medicine.anatomical_structure, biology.protein, Female, Insulin Resistance, business, Infertility, Female, hormones, hormone substitutes, and hormone antagonists, Hormone, Polycystic Ovary Syndrome

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0ea5e7c84ec54e3c2abae3dcad7cee3Test
https://pubmed.ncbi.nlm.nih.gov/33722534Test