المؤلفون: Xueying Li, Wanhua Qiu, Lu Deng, Jingjing Lin, Wenting Huang, Yuchen Xu, Mulan Zhang, Nigel C. Jones, Runxuan Lin, Huiqin Xu, Li Lin, Peijun Li, Xinshi Wang

المصدر: Journal of Translational Medicine. 20

مصطلحات موضوعية: Aging, Mice, Epilepsy, Seizures, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Animals, Apoptosis, Cognitive Dysfunction, General Medicine, Maze Learning, Glucocorticoids, General Biochemistry, Genetics and Molecular Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5de83cd96a7f669f4877a5c753965c8eTest
https://doi.org/10.1186/s12967-022-03618-xTest

المؤلفون: Jiang-Wen Lu, Wen-Jia Lei, Li-Jun Ling, Lu-Yao Wang, Yi-Kai Lin, Fan Zhang, Meng-Die Li, Fan Pan, Wang-Sheng Wang, Kang Sun

المصدر: Endocrinology. 163

مصطلحات موضوعية: CCAAT-Enhancer-Binding Protein-delta, Hydrocortisone, Aldo-Keto Reductases, Parturition, Fibroblasts, Dinoprostone, Endocrinology, Pregnancy, Cyclooxygenase 2, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Humans, Female, Amnion, Progesterone

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9865cc70c4d106b84bd25673fff4ccaeTest
https://doi.org/10.1210/endocr/bqac148Test

المؤلفون: Guohua An, Nan Wu, David A. Katz

المصدر: Journal of Clinical Pharmacology

مصطلحات موضوعية: 11β‐hydroxysteroid dehydrogenase type 1 inhibitor, animal structures, animal diseases, Pharmacology, nonlinear pharmacokinetics, Models, Biological, Pharmacometrics, Double-Blind Method, 11β-hydroxysteroid dehydrogenase type 1, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Humans, Pharmacology (medical), Volume of distribution, Drug disposition, biology, Dose-Response Relationship, Drug, Nonlinear pharmacokinetics, Chemistry, Low dose, biochemical phenomena, metabolism, and nutrition, Triazoles, bacterial infections and mycoses, drug development, target‐mediated drug disposition, population PK modeling, Drug development, Benzamides, biology.protein, bacteria, Steady state (chemistry), Dose selection

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eff33daac39b64b83c7d0607c563a09Test
http://europepmc.org/articles/PMC8596879Test

المؤلفون: Yiyan Wang, Huitao Li, Ren-Shan Ge, Yingfen Ying, Zengqiang Li, Changchang Li, Haoni Yan, Qiqi Zhu, Xiaoheng Li

المصدر: Toxicology Letters. 342:6-19

مصطلحات موضوعية: Male, 0301 basic medicine, endocrine system, medicine.medical_specialty, medicine.drug_class, Toxicology, CREB, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Proliferating Cell Nuclear Antigen, Internal medicine, Prepuberty, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Halogenated Diphenyl Ethers, medicine, Animals, Increased serum testosterone level, Cholesterol Side-Chain Cleavage Enzyme, Sexual Maturation, Cells, Cultured, Dose-Response Relationship, Drug, Molecular Structure, biology, Leydig cell, Chemistry, Stem Cells, Leydig Cells, SOX9 Transcription Factor, General Medicine, Luteinizing Hormone, Androgen, Rats, Proliferating cell nuclear antigen, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, Gene Expression Regulation, biology.protein, Follicle Stimulating Hormone, Luteinizing hormone, 030217 neurology & neurosurgery, Corn oil

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::687cea5414fb1fc5ac0934ca19e4dcc7Test
https://doi.org/10.1016/j.toxlet.2021.02.006Test

المؤلفون: Chloe G Fenton, Ana Crastin, Claire S Martin, Saicharan Suresh, Isabella Montagna, Bismah Hussain, Amy J Naylor, Simon W Jones, Morten S Hansen, Caroline M Gorvin, Maria Price, Andrew Filer, Mark S Cooper, Gareth G Lavery, Karim Raza, Rowan S Hardy

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 13; Pages: 7334

مصطلحات موضوعية: Inflammation, Organic Chemistry, Osteoclasts, General Medicine, Catalysis, Computer Science Applications, Inorganic Chemistry, Arthritis, Rheumatoid, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Osteoarthritis, Animals, Physical and Theoretical Chemistry, Bone Resorption, Corticosterone, 11β-hydroxysteroid dehydrogenase type 1, inflammatory bone loss, corticosteroids, polyarthritis, osteoclasts, rheumatoid arthritis, Molecular Biology, Glucocorticoids, Spectroscopy

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c65c4bf96ba1c70ece287e1ba71d565Test

المؤلفون: Karen E. Chapman, Michael Weingartner, Petra Klusonova, Denise V. Kratschmar, Gareth G. Lavery, Julia Birk, Alex Odermatt, Simon Stücheli

المصدر: British Journal of Pharmacology

مصطلحات موضوعية: 0301 basic medicine, Oxysterols, Lifelong Health and Therapeutics–Research Papers, medicine.drug_class, Carbenoxolone, Dehydrogenase, 11β‐hydroxysteroid dehydrogenase, Pharmacology, Bile Acids and Salts, Mice, 03 medical and health sciences, 0302 clinical medicine, 11-beta-Hydroxysteroid Dehydrogenase Type 1, medicine, bile acid, Animals, Glucocorticoids, Mice, Knockout, chemistry.chemical_classification, disease, Bile acid, Endoplasmic reticulum, inhibitor, 030104 developmental biology, Enzyme, chemistry, Knockout mouse, biomarker, Biomarker (medicine), glucocorticoid, Biomarkers, hormones, hormone substitutes, and hormone antagonists, 030217 neurology & neurosurgery, Glucocorticoid, Research Paper, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d65dfa9605f285c8c2884fa59f04a1bTest
https://doi.org/10.1111/bph.15367Test

المؤلفون: Cirillo, Nicola, Morgan, David J, Pedicillo, Maria Carmela, Celentano, Antonio, Lo Muzio, Lorenzo, McCullough, Michael J, Prime, Stephen S

المصدر: Cirillo , N , Morgan , D J , Pedicillo , M C , Celentano , A , Lo Muzio , L , McCullough , M J & Prime , S S 2017 , ' Characterisation of the cancer-associated glucocorticoid system : key role of 11β-hydroxysteroid dehydrogenase type 2 ' , British Journal of Cancer , vol. 117 , no. 7 , pp. 984-993 . https://doi.org/10.1038/bjc.2017.243Test

مصطلحات موضوعية: 11-beta-Hydroxysteroid Dehydrogenase Type 1, 11-beta-Hydroxysteroid Dehydrogenase Type 2, Adrenocorticotropic Hormone, CD8-Positive T-Lymphocytes, Carcinoma, Squamous Cell, Cell Adhesion, Cell Proliferation, Cortisone, Culture Media, Conditioned, Down-Regulation, Epithelial Cells, Gene Silencing, Glycyrrhetinic Acid, HT29 Cells, Humans, Hydrocortisone, Keratinocytes, MCF-7 Cells, Melanoma, Paracrine Communication, Receptors, Glucocorticoid, Skin Neoplasms, Journal Article

وصف الملف: application/pdf

العلاقة: https://research-information.bris.ac.uk/en/publications/68381e00-4bc4-4b46-955e-64c35ba40c62Test

الإتاحة: https://doi.org/10.1038/bjc.2017.243Test
https://hdl.handle.net/1983/68381e00-4bc4-4b46-955e-64c35ba40c62Test
https://research-information.bris.ac.uk/en/publications/68381e00-4bc4-4b46-955e-64c35ba40c62Test
https://research-information.bris.ac.uk/ws/files/135847643/BJC_REV1_final.pdfTest
https://research-information.bris.ac.uk/ws/files/135847642/bjc2017243.pdfTest

المؤلفون: Rahul Singh, Vijay Kumar Bhardwaj, Pralay Das, Rituraj Purohit

المصدر: Chemical communications (Cambridge, England). 58(32)

مصطلحات موضوعية: 11-beta-Hydroxysteroid Dehydrogenase Type 1, Materials Chemistry, Metals and Alloys, Ceramics and Composites, General Chemistry, Enzyme Inhibitors, hormones, hormone substitutes, and hormone antagonists, Catalysis, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f95153395d026c89a9f07631de053a7aTest
https://pubmed.ncbi.nlm.nih.gov/35362492Test

المؤلفون: Afroze Abbas, Marian Schini, Gemma Ainsworth, Sarah R Brown, Jamie Oughton, Rachel K Crowley, Mark S Cooper, Rebecca J Fairclough, Richard Eastell, Paul M Stewart

مصطلحات موضوعية: Niacinamide, Hydrocortisone, Endocrinology, Diabetes and Metabolism, Biochemistry (medical), Clinical Biochemistry, Osteocalcin, Biochemistry, Postmenopause, Bone Diseases, Metabolic, Endocrinology, Piperidines, 11-beta-Hydroxysteroid Dehydrogenase Type 2, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Humans, Female, Bone Remodeling, Glucocorticoids, hormones, hormone substitutes, and hormone antagonists

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e162639b53ee80003f49c30138444f10Test
https://eprints.whiterose.ac.uk/184441/7/dgac100.pdfTest

المؤلفون: David M. Burns, Chunhong He, Yun-Long Li, Jincong Zhuo, Ding-Quan Qian, Lihua Chen, Ravi Jalluri, Sharon Diamond, Maryanne B. Covington, Yanlong Li, Richard Wynn, Peggy Scherle, Swamy Yeleswaram, Gregory Hollis, Steve Friedman, Brian Metcalf, Wenqing Yao

المصدر: Bioorganicmedicinal chemistry letters. 73

مصطلحات موضوعية: Metabolic Syndrome, Diabetes Mellitus, Type 2, Hydrocortisone, Organic Chemistry, Clinical Biochemistry, Drug Discovery, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Pharmaceutical Science, Molecular Medicine, Humans, Enzyme Inhibitors, Molecular Biology, Biochemistry

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbbafe40c80b68974928f2b0a5dbd9bdTest
https://pubmed.ncbi.nlm.nih.gov/35835377Test