المؤلفون: Demir, Aylin Bican, Bargiotas, Panagiotis, Berktaş, Deniz Tuncel, İsmailoğulları, Sevda, Akyıldız, Utku Oğan, Karadeniz, Derya, Şenel, Gülçin Benbir, Bassetti, Claudio L. A.

المصدر: Demir, Aylin Bican; Bargiotas, Panagiotis; Berktaş, Deniz Tuncel; İsmailoğulları, Sevda; Akyıldız, Utku Oğan; Karadeniz, Derya; Şenel, Gülçin Benbir; Bassetti, Claudio L. A. (2023). A Turkish Validity and Reliability Study of the Swiss Narcolepsy Scale. Clinical and translational neuroscience, 7(3), p. 16. MDPI 10.3390/ctn7030016

مصطلحات موضوعية: 610 Medicine & health

الوصف: Background: The clinical evaluation of a patient complaining of excessive daytime sleepiness is of crucial importance for the diagnosis of narcolepsy. The Swiss Narcolepsy Scale (SNS) was developed in 2004 as a screening tool for patients with narcolepsy and shown in three different studies to have a high sensitivity and specificity for narcolepsy type 1 (NT1). The aim of this study was to assess the validity and reliability of the Turkish version of SNS (SNS-TR). Patients and Methods: Twenty-one healthy controls, 26 patients with idiopathic hypersomnia, and 27 patients with narcolepsy were recruited from five accredited sleep centers in Turkey. Pearson’s correlation coefficient and degree of freedom were used to determine the validity of each question. Cronbach’s alpha was calculated to assess the internal consistency or reliability of Likert-type questions. The inter-rater reliability was tested using Cohen’s kappa analysis, and the intra-class correlation coefficient (ICC) was used to evaluate the validity and reliability between two evaluations with a one-month interval. Results: Sensitivity and specificity of SNS-TR were 90.5% and 100%, respectively, for diagnosing NT1. Cronbach’s alpha was 0.976, showing a highly reliable level of internal consistency. The inter-rater reliability of the questions and the validity and reliability between two evaluations were moderate or above. Conclusion: This study provides evidence for the validity and reliability of SNS-TR in diagnosing and discriminating NT1 from other disorders of hypersomnolence with a very high sensitivity and specificity.

وصف الملف: application/pdf

العلاقة: https://boris.unibe.ch/191265Test/

الإتاحة: https://doi.org/10.3390/ctn7030016Test
https://boris.unibe.ch/191265/1/Demir__2023__A_Turkish_Validity_and_Reliability_Study.pdfTest
https://boris.unibe.ch/191265Test/

المؤلفون: Per, Hüseyin, İsmailoğulları, Sevda, Çıplaklıgil, Aslı, Kurt Gök , Duygu

الوصف: SS-13 PEDİATRİK YAŞ GRUBUNDA POLİSOMNOGRAFİ ENDİKASYONLARI VE SONUÇLARI: TEK MERKEZİN 23YILLIK DENEYİMİASLI ÇIPLAKLIGİL, SEVDA İSMAİLOĞULLARI, DUYGU KURT GÖK, HÜSEYİN PERERCİYES ÜNİVERSİTESİ TIP FAKÜLTESİ NÖROLOJİ ANABİLİM DALIKAYSERİ ŞEHİR HASTANESİ NÖROLOJİ KLİNİĞİERCİYES ÜNİVERSİTESİ TIP FAKÜLTESİ PEDİATRİK NÖROLOJİ BİLİM DALIAmaç:Bu çalışmada Erciyes Üniversitesi Nöroloji Anabilim Dalı Uyku Laboratuvarı’nda polisomnografi (PSG) yapılan 18yaş altı çocuk hastaları retrospektif olarak incelemek, ön tanılar, semptomlar ile PSG sonuçlarını karşılaştırmakamaçlanmıştır.Metot:2000-2023 yılları arasında laboratuvarımızda PSG ile değerlendirilen çocukların demografik ve klinik özellikleri,ön tanıları, eşlik eden diğer sistemik hastalıkları ve PSG sonuçları geriye dönük olarak değerlendirildi.Bulgular:164 hastanın ,3’ü (n:71) kız, ,7’si (n:93) erkekti. Başvurudaki ortalama yaş 6-14’tü. Hastaların, % 52,5’iise parasomni, ,8’i tanıklı apne ,9’u horlama, ,4’ü gündüz artmış uykululuk (GAU), %6,7’si huzursuzbacaklar sendromu semptom ve ön tanılarıyla gönderilmişti.97 parasomni amaçlı istem vardı.16 tanesi somnanbulizm,12’si uyku terörü,25’i konfüzyonel uyanma, 33 taneside epileptik nöbet- parasomni ayrımı için istenmişti. 21’inde parasomni atağı tespit edildi. Hepsi de konfüzyoneluyanmayla uyumluydu. Yaşları en küçük 6, en büyük 12’ydi. 97 parasomni istem hastasının 36’sı epilepsi içintedavi almaktaydı ve bu hastaların 5’inde parasomni atak tespit edildi.65 çocuktan OSAS ön tanısıyla PSG istenmişti. 39 kişide tanıklı apne,26 kişide horlama vardı. 44’ünde hafif,11’indeorta 8’inde ağır OSAS tespit edildi.2’ sinin PSG’si normaldi. 7’sine adenotonsillektomi,1’ine polipektomi,2’sinePAP tedavisi, 7’sine rinit tedavisi uygulandı.4 nöromüskuler bozukluk olgumuzda (2 duchenne muskuler distrofi(DMD),1 konjenital myastenia gravis (MG), 1 MG) 2 DMD’te normal, 1 konjenital MG’te ağır OSAS, 1 MG’te ortaOSAS tespit edildi.Sendromik vakaların tamamı apne ön tanısıyla gönderilmişti.2 tane klippel feil sendromundaağır OSAS, 2 down sendromu ...

العلاقة: c8c3d73d-cce3-439c-95ef-dc45cbbaf25c; https://avesis.erciyes.edu.tr/publication/details/c8c3d73d-cce3-439c-95ef-dc45cbbaf25c/oaiTest

الإتاحة: https://avesis.erciyes.edu.tr/publication/details/c8c3d73d-cce3-439c-95ef-dc45cbbaf25c/oaiTest

المؤلفون: Hacioglu, Aysa, Karaca, Zuleyha, Dogan, Kesim Hatice, Ismailogullari, Sevda, Emre, Urhan Muhammed, Sezgin, Caglar Asli, Kalay, Nihat, Karabiyik, Ugur, Taheri, Serpil, Unluhizarci, Kursad, Kelestemur, Fahrettin

المصدر: Endocrine Abstracts ; ISSN 1479-6848

الإتاحة: https://doi.org/10.1530/endoabs.99.p410Test
http://www.endocrine-abstracts.org/ea/0099/ea0099P410Test

المؤلفون: İsmailoğulları, Sevda, Erdoğ Şahin, Nagihan, Ertürk Zararsız, Gözde, Cırdı, Gökçe, Kondolot, Meda

الوصف: Objective: To know cultural characteristics of infant sleep pattern andguide the families can be useful to prevent sleep problems. The aim ofthis study to determine the sleep habits during infancy and to evaluatethe effectiveness of sleep training. Materials and Methods: This longitudinal study included 127 healthyinfants. Infants were randomly assigned to intervention group [(IG)n=33] or control group [(CG) n=94] and followed up from the 3rd to18th months at well-child-visits. Face to face sleep training was given tothe IG firstly in the 3rd month and then subsequent follow-ups. Familiesin both groups filled out a detailed questionnaire at each visit. Results: Bed sharing was not detected in the IG. The frequency of rockingwas lower in the IG in each period, the difference was significant onlyat the sixth month (p=0.006). The frequency of sleeping in the supineposition compared to the side position was higher in the IG than CG atthe 3rd, 6th and 9th months (p=0.013, p=0.005, p=0.003; respectively).Bedtime was earlier and duration to fall asleep after night awakeningswas shorter in the IG than CG at 9 and 12 months (p=0.009, p=0.018;p<0.001, p=0.002; respectively). Conclusion: Sleep training during the infancy provide to sleep supineposition, prevents rocking during falling asleep, provide earlier bedtime,and shortens the duration to fall asleep again after night awakenings.Further studies are needed to determine the effectiveness of sleeptraining and to determine the main components of the training. Keywords: Sleep pattern, infancy, sleep training

العلاقة: 6e8a6554-5fa3-4cf3-9f51-3721b2dfe6d1; https://avesis.erciyes.edu.tr/publication/details/6e8a6554-5fa3-4cf3-9f51-3721b2dfe6d1/oaiTest

الإتاحة: https://doi.org/10.4274/jtsm.galenos.2021.55265Test
https://avesis.erciyes.edu.tr/publication/details/6e8a6554-5fa3-4cf3-9f51-3721b2dfe6d1/oaiTest

المؤلفون: Çıplaklıgil, Aslı, Yetkin, Mehmet Fatih, Benli, Şeyma, İsmailoğulları, Sevda

العلاقة: 897d7b4f-6f62-4e0e-bdbd-751a774686ae; https://avesis.erciyes.edu.tr/publication/details/897d7b4f-6f62-4e0e-bdbd-751a774686ae/oaiTest

الإتاحة: https://avesis.erciyes.edu.tr/publication/details/897d7b4f-6f62-4e0e-bdbd-751a774686ae/oaiTest

المؤلفون: ZARARSIZ, GÖKMEN, ALDEMİR, RAMAZAN, Karaca, Zuleyha, Kurt Gok, Duygu, Kelestimur, Fahrettin, TOKMAKÇI, MAHMUT, Firat, Sedat Tarik, İSMAİLOĞULLARI, SEVDA

الوصف: Objectives: Our aim was to investigate the effects of endogenous chronic hypercortisolism on sleep electroencephalogram (EEG) and differences between the adrenocorticotropic hormone (ACTH)-dependent and independent Cushing Syndrome (CS) patients through a sleep spectral analysis program. Methods: A total of 32 patients diagnosed as having endogenous CS (12 ACTH-dependent and 20 ACTH-independent) and a control group comprising 16 healthy individuals were included in the study. Polysomnographic analysis was performed. Blood samples were collected at 08:00 AM for analysis of ACTH and basal cortisol, and at 00:00 AM for midnight cortisol levels. The frequency and power of the slow wave activity (SWA), theta, alpha, and beta waves of the first and last non-rapid eye movement (NREM) cycles were measured with a spectral analysis program. Results: The CS patient group had higher SWA power, especially in the first NREM cycle. In the ACTH-dependent group, SWA maximum and mean power values were higher in the frontal channels in the first NREM, compared to the last NREM sleep stage (p<0.05). Conclusion: Cortisol has been found to be associated with SWA waves, making these waves higher in power, especially in the first NREM phase. This difference was much less pronounced in the final NREM sleep stage. The difference between the first and last NREM sleep stages with respect to the power of SWA in the frontal channel in the ACTH-dependent group suggests that not only cortisol but also high levels of ACTH affect the power of slow waves during sleep.

العلاقة: 0d980a96-5367-4056-be0e-38b314762839; https://avesis.erciyes.edu.tr/publication/details/0d980a96-5367-4056-be0e-38b314762839/oaiTest

الإتاحة: https://doi.org/10.1016/j.neucli.2023.102893Test
https://avesis.erciyes.edu.tr/publication/details/0d980a96-5367-4056-be0e-38b314762839/oaiTest

المؤلفون: Kurt Gök, Duygu, İsmailoğulları, Sevda, Aldemir, Ramazan, Tokmakçı, Mahmut, Firat, Sedat Tarik, Karaca, Züleyha, Keleştemur, Fahrettin, Zararsiz, Gökmen

المصدر: Neurophysiologie Clinique ; volume 53, issue 5, page 102893 ; ISSN 0987-7053

مصطلحات موضوعية: Physiology (medical), Neurology (clinical), Neurology, General Medicine

الإتاحة: https://doi.org/10.1016/j.neucli.2023.102893Test
https://api.elsevier.com/content/article/PII:S0987705323000503?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0987705323000503?httpAccept=text/plainTest

المؤلفون: İSMAİLOĞULLARI, SEVDA, ZARARSIZ, GÖKMEN, Yavuz, Fatih, PER, HÜSEYİN, Kabaagil, Burak

الوصف: Objective: Medical students are under the risk of developing sleep disorders due to heavy curriculum and long studying hours. This condition causes sleep disorders to occur more frequently in medical faculty students compared to the normal society. The present study aims to determine the prevalence of sleep disorders in medical students and the examination of change according to classes.

العلاقة: cf5018b7-0143-459c-825d-fd9c9a224726; https://avesis.erciyes.edu.tr/publication/details/cf5018b7-0143-459c-825d-fd9c9a224726/oaiTest

الإتاحة: https://doi.org/10.4274/jtsm.galenos.2019.46036Test
https://avesis.erciyes.edu.tr/publication/details/cf5018b7-0143-459c-825d-fd9c9a224726/oaiTest

المؤلفون: Bal, Cengiz, Öztürk, Ahmet, Çiçek, Betül, Özdemir, Ahmet, Zararsız, Gökmen, Ünalan, Demet, Ertürk Zararsız, Gözde, Korkmaz, Selçuk, Göksülük, Dinçer, Eldem, Vahap, İsmailoğulları, Sevda, Erdem, Emine, Mazıcıoğlu, Mümtaz M, Kurtoğlu, Selim

المساهمون: Biyoistatistik

الوصف: Objective: As in adults, hypertension is also an important risk factor for cardiovascular disease in children. We aimed to evaluate the effect of sleep duration on blood pressure in normal weight Turkish children aged between 11-17 years. Methods: This cross-sectional study was conducted in the primary and secondary schools of the two central and ten outlying districts of Kayseri, Turkey. Subjects were 2860 children and adolescents (1385 boys, 1475 girls). Systolic and diastolic blood pressures were measured according to the recommendations of the Fourth Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents. Sleep duration was classified as follows: ≤8 hours, 8.1-8.9 hours, 9.0-9.9 hours or ≥10 hours. Results: For short sleeper boys and girls (participants with a sleep duration ≤8 h) the prevalence of prehypertension and hypertension was 35.0% and 30.8%, respectively. In univariate binary logistic regression analyses (age-adjusted), each unit increment in sleep duration (hours) in boys and girls, decreased the prehypertension and hypertension risk by 0.89 [odds ratio (OR)] [confidance interval (CI); 0.82-0.98] and 0.88 (OR) (CI; 0.81-0.97), respectively (p<0.05). In multiple binary logistic regression analyses [age- and body mass index (BMI)-adjusted] the location of the school and sleep duration categories were shown to be the most important factors for prehypertension and hypertension in both genders, while household income was the most important factor, only in boys. Conclusions: A sleep duration ≤8 h is an independent risk factor for prehypertension and hypertension in Turkish children aged 11-17 years.

وصف الملف: text/plain; application/pdf

العلاقة: Journal of Clinical Research in Pediatric Endocrinology; https://doi.org/10.4274/jcrpe.4557Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838373Test/; http://hdl.handle.net/11655/16386Test; 10; 51; 58

الإتاحة: https://doi.org/10.4274/jcrpe.4557Test
http://hdl.handle.net/11655/16386Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838373Test/

المؤلفون: Kurtoglu, Selim, Ismailogullari, Sevda, Cicek, Betül, Korkmaz, Selcuk, Ozdemir, Ahmet, ZARARSIZ, GÖZDE, ZARARSIZ, Gökmen, Mazicioglu, MUSTAFA MÜMTAZ, Erdem, Emine, ÜNALAN, Demet, ÖZTÜRK, Ahmet, GÖKSÜLÜK, DİNÇER, Bal, Cengiz, Eldem, Vahap

الوصف: © 2018 by Turkish Pediatric Endocrinology and Diabetes Society.Objective: As in adults, hypertension is also an important risk factor for cardiovascular disease in children. We aimed to evaluate the effect of sleep duration on blood pressure in normal weight Turkish children aged between 11-17 years. Methods: This cross-sectional study was conducted in the primary and secondary schools of the two central and ten outlying districts of Kayseri, Turkey. Subjects were 2860 children and adolescents (1385 boys, 1475 girls). Systolic and diastolic blood pressures were measured according to the recommendations of the Fourth Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents. Sleep duration was classified as follows: ≤8 hours, 8.1-8.9 hours, 9.0-9.9 hours or ≥10 hours. Results: For short sleeper boys and girls (participants with a sleep duration ≤8 h) the prevalence of prehypertension and hypertension was 35.0% and 30.8%, respectively. In univariate binary logistic regression analyses (age-adjusted), each unit increment in sleep duration (hours) in boys and girls, decreased the prehypertension and hypertension risk by 0.89 [odds ratio (OR)] [confidance interval (CI); 0.82-0.98] and 0.88 (OR) (CI; 0.81-0.97), respectively (p<0.05). In multiple binary logistic regression analyses [age- and body mass index (BMI)-adjusted] the location of the school and sleep duration categories were shown to be the most important factors for prehypertension and hypertension in both genders, while household income was the most important factor, only in boys. Conclusions: A sleep duration ≤8 h is an independent risk factor for prehypertension and hypertension in Turkish children aged 11-17 years.

العلاقة: fd0fcc8f-cbaf-42da-b6ad-903509abed92; https://avesis.erciyes.edu.tr/publication/details/fd0fcc8f-cbaf-42da-b6ad-903509abed92/oaiTest

الإتاحة: https://doi.org/10.4274/jcrpe.4557Test
https://avesis.erciyes.edu.tr/publication/details/fd0fcc8f-cbaf-42da-b6ad-903509abed92/oaiTest