التفاصيل البيبلوغرافية
| العنوان: |
Importance of mitochondrial haplotypes and maternal lineage in sprint performance among individuals of West African ancestry. |
| المؤلفون: |
Deason, M., Scott, R., Irwin, L., Macaulay, V., Fuku, N., Tanaka, M., Irving, R., Charlton, V., Morrison, E., Austin, K., Pitsiladis, Y. P. |
| المصدر: |
Scandinavian Journal of Medicine & Science in Sports; Apr2012, Vol. 22 Issue 2, p217-223, 7p |
| مصطلحات موضوعية: |
BLACK people, COMPARATIVE studies, CONFIDENCE intervals, DNA, EPIDEMIOLOGY, FISHER exact test, GENETICS, MOTHERS, POLYMERASE chain reaction, QUESTIONNAIRES, RESEARCH funding, RUNNING, DATA analysis, ELITE athletes, CASE-control method |
| مصطلحات جغرافية: |
WEST Africa, JAMAICA, UNITED States |
| مستخلص: |
Mitochondrial DNA (mtDNA) is inherited solely along the matriline, giving insight into both ancestry and prehistory. Individuals of sub-Saharan ancestry are overrepresented in sprint athletics, suggesting a genetic advantage. The purpose of this study was to compare the mtDNA haplogroup data of elite groups of Jamaican and African-American sprinters against respective controls to assess any differences in maternal lineage. The first hypervariable region of mtDNA was haplogrouped in elite Jamaican athletes ( N=107) and Jamaican controls ( N=293), and elite African-American athletes ( N=119) and African-American controls ( N=1148). Exact tests of total population differentiation were performed on total haplogroup frequencies. The frequency of non-sub-Saharan haplogroups in Jamaican athletes and Jamaican controls was similar (1.87% and 1.71%, respectively) and lower than that of African-American athletes and African-American controls (21.01% and 8.19%, respectively). There was no significant difference in total haplogroup frequencies between Jamaican athletes and Jamaican controls ( P=0.551 ± 0.005); however, there was a highly significant difference between African-American athletes and African-American controls ( P<0.001). The finding of statistically similar mtDNA haplogroup distributions in Jamaican athletes and Jamaican controls suggests that elite Jamaican sprinters are derived from the same source population and there is neither population stratification nor isolation for sprint performance. The significant difference between African-American sprinters and African-American controls suggests that the maternal admixture may play a role in sprint performance. [ABSTRACT FROM AUTHOR] |
|
Copyright of Scandinavian Journal of Medicine & Science in Sports is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
