التفاصيل البيبلوغرافية
| العنوان: |
Operational definitions of sarcopenia and their associations with 5-year changes in falls risk in community-dwelling middle-aged and older adults. |
| المؤلفون: |
Scott, D., Hayes, A., Sanders, K., Aitken, D., Ebeling, P., Jones, G. |
| المصدر: |
Osteoporosis International; Jan2014, Vol. 25 Issue 1, p187-193, 7p, 2 Charts, 1 Graph |
| مصطلحات موضوعية: |
RISK factors of falling down, ACADEMIC medical centers, ANALYSIS of variance, CONFIDENCE intervals, EXERCISE tests, LONGITUDINAL method, MUSCLE contraction, MUSCLE strength, MUSCULAR atrophy, REGRESSION analysis, RESEARCH funding, SEX distribution, STATISTICS, T-test (Statistics), INTER-observer reliability, DATA analysis software, DESCRIPTIVE statistics, PHOTON absorptiometry |
| مصطلحات جغرافية: |
TASMANIA |
| مستخلص: |
Summary: Sarcopenia may be diagnosed in the clinic using operational definitions based on low muscle mass or function. This prospective, population-based study revealed that sex-specific associations may exist between operational definitions of sarcopenia and falls in community-dwelling middle-aged and older adults. Introduction: The objective of this study is to verify associations between sarcopenia and falls risk and to determine changes in sarcopenia prevalence over 5 years in middle-aged and older men and women according to different anthropometric and performance-based operational definitions. Methods: N = 681 volunteers (48 % female; mean ± SD age 61.4 ± 7.0 years) participated in baseline and follow-up assessments (mean 5.1 ± 0.5 years later). Appendicular lean mass (ALM) was assessed by dual-energy X-ray absorptiometry, hand grip (HGS) and lower-limb (LLS) strength were assessed by dynamometry, and falls risk was determined using the physiological profile assessment. Anthropometric definitions (ALM/height squared [ALM-H], ALM/weight × 100 and a residuals method [ALM-R]) and performance-based definitions (HGS, LLS and upper- and lower-limb muscle quality [LMQ]) of sarcopenia were examined. The lowest 20 % of the sex-specific distribution for each definition at baseline was classified as sarcopenia. Results: Sarcopenia prevalence increased after 5 years for all operational definitions except ALM-H (men: −4.0 %; women: −5.5 %). Men classified with sarcopenia according to anthropometric definitions, and women classified with sarcopenia according to performance-based definitions, had significant increases in falls risk over 5 years (all P < 0.05) compared to individuals without sarcopenia. Significant sex interactions were observed for ALM-R, LLS and LMQ (all P < 0.05) definitions. Conclusions: Sarcopenia prevalence generally increases at a higher rate when assessed using performance-based definitions. Sarcopenia is associated with increases in falls risk over 5 years in community-dwelling middle-aged and older adults, but sex-specific differences may exist according to different anthropometric or performance-based definitions. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
