مؤتمر
Biomechanics of chiasmal compression: Sensitivity of the mechanical behaviours of nerve fibres to variations in material property and geometry
| العنوان: | Biomechanics of chiasmal compression: Sensitivity of the mechanical behaviours of nerve fibres to variations in material property and geometry |
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| المؤلفون: | Wang, Xiaofei, Neely, Andrew, McIlwaine, Gawn G., Lueck, Christian |
| المساهمون: | Huerta, A., Onate, E., Oliver, X. |
| المصدر: | 11th World Congress on Computational Mechanics, WCCM 2014, 5th European Conference on Computational Mechanics, ECCM 2014 and 6th European Conference on Computational Fluid Dynamics, ECFD 2014 |
| بيانات النشر: | International Center for Numerical Methods in Engineering |
| المجموعة: | Australian National University: ANU Digital Collections |
| مصطلحات موضوعية: | Keywords: Biomechanics, Computational fluid dynamics, Computational mechanics, Design of experiments, Eye protection, Fibers, Materials properties, Sensitivity analysis, Crossing angles, Finite element modelling, Five parameters, Hemianopia, Mechanical behaviour, M Bitemporal hemianopia, Chiasmal compression, Design of experiment, Multi-scale |
| جغرافية الموضوع: | Spain |
| الوقت: | Barcelona, Spain |
| الوصف: | The mechanism of bitemporal hemianopia is still unclear. Previous research suggested that the nerve fibre packing pattern may contribute to the selective damage of nasal (crossed) nerve fibres. Numerical models were built using finite element modelling to study the biomechanics of optic nerve fibres. The sensitivity of the mechanical behaviours of the nerve fibres to variations of five parameters in the nerve fibre model were investigated using design of experiments (DOE). Results show that the crossing angle is a very significant factor that affects a wide range of responses of the model. The strain difference between the crossed and the uncrossed nerve fibres may account for the phenomenon of bitemporal hemianopia. This work also highlights the need for more accurate material properties of the tissues in the model and an improved understanding of the microstructure of the optic chiasm. |
| نوع الوثيقة: | conference object |
| اللغة: | unknown |
| ردمك: | 978-84-942844-7-2 84-942844-7-9 |
| العلاقة: | Joint 11th World Congress on Computational Mechanics, WCCM 2014, the 5th European Conference on Computational Mechanics, ECCM 2014 and the 6th European Conference on Computational Fluid Dynamics, ECFD 2014; http://hdl.handle.net/1885/65572Test; https://openresearch-repository.anu.edu.au/bitstream/1885/65572/7/01_Wang_Biomechanics_of_chiasmal_2014.pdf.jpgTest |
| الإتاحة: | http://hdl.handle.net/1885/65572Test https://openresearch-repository.anu.edu.au/bitstream/1885/65572/7/01_Wang_Biomechanics_of_chiasmal_2014.pdf.jpgTest |
| رقم الانضمام: | edsbas.505F8C29 |
| قاعدة البيانات: | BASE |
| ردمك: | 9788494284472 8494284479 |
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