التفاصيل البيبلوغرافية
| العنوان: |
Appraisal of Antihyperlipidemic Activities of Lentinus lepideus in Hypercholesterolemic Rats. |
| المؤلفون: |
Ki Nam Yoon, Jae Seong Lee, Hye Young Kim, Kyung Rim Lee, Pyung Gyun Shin, Jong Chun Cheong, Young Bok Yoo, Alam, Nuhu, Tai Moon Ha, Tae Soo Lee |
| المصدر: |
Mycobiology; Dec2011, Vol. 39 Issue 4, p283-289, 7p, 2 Black and White Photographs, 2 Charts, 2 Graphs |
| مصطلحات موضوعية: |
GEL electrophoresis, LENTINUS, MUSHROOMS, HISTOPATHOLOGY, LIPIDS |
| مصطلحات جغرافية: |
SOUTH Korea |
| مستخلص: |
The wild edible mushroom, Lentinus lepideus has recently been cultivated for commercial use in Korea. While the mushroom has been widely used for nutritional and medicinal purposes, the possible anti-hyperlipidemic action is unclear. The effects of dietary L. lepideus on plasma and feces biochemical and on the liver histological status were investigated in hypercholesterolemic rats. Six-wk-old female Sprague-Dawley albino rats were divided into three groups of 10 rats each. Biochemical and histological examinations were performed. A diet containing 5% L. lepideus fruiting bodies reduced plasma total cholesterol, triglyceride, low-density lipoprotein, total lipid, phospholipids, and the ratio of low-density to high-density lipoprotein. Body weight was reduced. The diet did not adversely affect plasma biochemical and enzyme profiles. L. lepideus reduced significantly plasma β- and pre-β-lipoprotein, while α-lipoprotein content was increased. A histological study of hepatic cells by conventional hematoxylin-eosin and oil red O staining revealed normal findings for mushroom-fed hypercholesterolemic rats. The present study suggests that a diet supplemented with L. lepideus can provide health benefits by acting on the atherogenic lipid profile in hypercholesterolemic rats. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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