التفاصيل البيبلوغرافية
| العنوان: |
The Role of Surveillance Inspections in Reducing False-Positives of SARS-CoV-2 Omicron Variants during the COVID-19 Epidemic. |
| المؤلفون: |
Liu, Li-Li, Zheng, Yu-Hong, Zhang, You-Quan, Lin, Jin-Piao, Luo, Zhi-Lin, Yu, Liu-Min, Gao, Shi-Hua, Chen, Falin |
| المصدر: |
Canadian Journal of Infectious Diseases & Medical Microbiology; 4/19/2023, Vol. 2023, p1-8, 8p |
| مصطلحات موضوعية: |
SARS-CoV-2 Omicron variant, COVID-19 pandemic, INVERSE relationships (Mathematics), QUALITY control |
| مصطلحات جغرافية: |
QUANZHOU Shi (China) |
| مستخلص: |
Objective. This study aims to assess the effectiveness of surveillance inspections conducted by the provincial health committee in Quanzhou city during a COVID-19 outbreak in reducing false-positive results in SARS-CoV-2 RT-PCR assays. Method. The team conducted on-site inspections of laboratories that participated in mass screening, recording any violations of rules. Results. The positive cases in five rounds of mass screening were 23, 173, and 4 in Licheng District, Fengze District, and Luojang District, respectively. The false-positive rates in the five rounds of mass screening were 0.0099%, 0.0063%, 0.0018%, 0.0006%, and 0%, respectively. The study also recorded that the number of violations in the seven selected laboratories was 36, 68, 69, 42, 60, 54 and 47. The corresponding false-positive rates were 0.0012%, 0.0060%, 0.0082%, 0.0032%, 0.0060%, 0.0027%, and 0.0021%, respectively. The study found a positive correlation between false-positive rates and the number of violations (r = 0.905, P = 0.005), and an inverse correlation between false-positive rates and the frequency of surveillance inspections (r = −0.950, P < 0.001). Conclusion. Daily surveillance inspection in laboratories can remind laboratories to strictly comply with standard procedures, focus on laboratory quality control, and reduce the occurrence of false-positive cases in SARS-CoV-2 nucleic acid tests to some extent. This study recommends that government decision-making departments establish policies and arrange experts to conduct daily surveillance inspections to improve laboratory quality control. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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