دورية أكاديمية
Nucleotide sequence variation of the major histocompatibility complex class II DQA1 gene in different cattle breeds from Nigeria and New Zealand
| العنوان: | Nucleotide sequence variation of the major histocompatibility complex class II DQA1 gene in different cattle breeds from Nigeria and New Zealand |
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| المؤلفون: | Oladosu, OJ, Haruna, IL, Hadebe, SA, Zhou, Huitong, Hickford, Jonathan |
| بيانات النشر: | Elsevier |
| سنة النشر: | 2021 |
| المجموعة: | Lincoln University (New Zealand): Lincoln U Research Archive |
| مصطلحات موضوعية: | major histocompatibility complex (MHC), DQA1, PCR-SSCP, polymorphism, alleles, ANZSRC::3009 Veterinary sciences, ANZSRC::3109 Zoology, Animals, Cattle, HLA-DQ Antigens, Species Specificity, Genes, MHC Class II, Base Sequence, Nigeria, New Zealand |
| جغرافية الموضوع: | Netherlands |
| الوصف: | The major histocompatibility complex (MHC) plays a role in immune response. Among other activities, the bovine MHC genes (BoLA) trigger immune responses, including the activation of antibody-producing B-cells. In this study, White Fulani (n = 24), Red Bororo (n = 5) and Holstein-White × Fulani-cross (n = 11) cattle from Nigeria, and New Zealand Holstein-Friesian × Jersey-cross (n = 40) cattle were used to investigate variability in exon 2 of BoLA-DQA1. Ten alleles were identified using a PCR-Single Strand Conformation Polymorphism (SSCP) approach and their nucleotide sequences confirmed by DNA sequencing. A total of 12.60 % of all nucleotide positions analysed were revealed to be variable and two novel BoLA-DQA1 alleles are reported here for the first time. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | 6 pages; Print-Electronic |
| اللغة: | English |
| تدمد: | 1873-2534 0165-2427 |
| العلاقة: | The original publication is available from Elsevier - https://doi.org/10.1016/j.vetimm.2021.110273Test - http://dx.doi.org/10.1016/j.vetimm.2021.110273Test; Veterinary Immunology and Immunopathology; https://doi.org/10.1016/j.vetimm.2021.110273Test; S0165-2427(21)00091-X; https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=elements_prod&SrcAuth=WosAPI&KeyUT=WOS:000659520400003&DestLinkType=FullRecord&DestApp=WOS_CPLTest; 34044268 (pubmed); https://hdl.handle.net/10182/14776Test |
| DOI: | 10.1016/j.vetimm.2021.110273 |
| الإتاحة: | https://doi.org/10.1016/j.vetimm.2021.110273Test https://hdl.handle.net/10182/14776Test https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=elements_prod&SrcAuth=WosAPI&KeyUT=WOS:000659520400003&DestLinkType=FullRecord&DestApp=WOS_CPLTest |
| حقوق: | © 2021 Elsevier B.V. All rights reserved. |
| رقم الانضمام: | edsbas.3AD0B922 |
| قاعدة البيانات: | BASE |
| تدمد: | 18732534 01652427 |
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| DOI: | 10.1016/j.vetimm.2021.110273 |