Fluorimetric determination of high levels of middle molecules in plasma of uremic patients under treatment with hemodialysis or hemofiltration.

التفاصيل البيبلوغرافية
العنوان: Fluorimetric determination of high levels of middle molecules in plasma of uremic patients under treatment with hemodialysis or hemofiltration.
المؤلفون: Russo, Luigi
المساهمون: Huggins Laboratory
المصدر: ESAO 10th Annual Meeting ; Xth ESAO Annual Meeting. Abstract Book, 1983; p.83. ; https://hal.archives-ouvertes.fr/hal-03879536Test ; Xth ESAO Annual Meeting. Abstract Book, 1983; p.83., Sep 1983, Bologna, Italy. pp.73
بيانات النشر: HAL CCSD
سنة النشر: 1983
المجموعة: Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe)
مصطلحات موضوعية: middle molecules, fluorometry, hemodialysis, uremia, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
جغرافية الموضوع: Bologna, Italy
الوصف: International audience ; Free and weakly bound middle molecules were determined in plasma of 16 uremic patients by ultrafiltration or anafiltration and fluorometry. A fluorescence scan was performed on liquids and peaks ot emission of different wavelengths recorded. Samples were assayed before and after treatment with hemodialysis or hemofiltra- tion.The results have shown:-high concentrations of MM in uremic plasma;-a decrease of concentration of MM in plasma after HD and HF (35%);-no difference in decrease of weakly bound middle molecules after HD or HF. A nomogram was deviced for the combined evaluation of free and bound molecules. Fluorimetric scan of filtrates have shown different patterns before and after the excretory procedures indicating the presence of peaks resistant to the procedures. Molecular weight and protein binding are two fundamental properties of toxic compounds to be evaluated for the decision on the most efficient artificial excretory system.
نوع الوثيقة: conference object
اللغة: English
العلاقة: hal-03879536; https://hal.archives-ouvertes.fr/hal-03879536Test
الإتاحة: https://hal.archives-ouvertes.fr/hal-03879536Test
رقم الانضمام: edsbas.FB3417CB
قاعدة البيانات: BASE