التفاصيل البيبلوغرافية
| العنوان: |
Occurrence, elimination, enantiomeric distribution and intra-day variations of chiral pharmaceuticals in major wastewater treatment plants in Beijing, China. |
| المؤلفون: |
Duan, Lei, Zhang, Yizhe, Wang, Bin, Deng, Shubo, Huang, Jun, Wang, Yujue, Yu, Gang |
| المصدر: |
Environmental Pollution; Aug2018, Vol. 239, p473-482, 10p |
| مصطلحات موضوعية: |
CHIRAL drugs, SEWAGE disposal plants, METOPROLOL, VENLAFAXINE |
| مصطلحات جغرافية: |
BEIJING (China) |
| مستخلص: |
The occurrence, eliminations, enantiomeric distribution and intra-day variations of five chiral pharmaceuticals (three beta-blockers and two antidepressants) were investigated in eight major WWTPs in Beijing, China. The results revealed that metoprolol (MTP) and venlafaxine (VFX) were of the highest concentrations among the five determined pharmaceuticals with mean concentrations of 803 ng L −1 and 408 ng L −1 , respectively in influents, and 354 ng L −1 and 165 ng L −1 in effluents, respectively. Their removal efficiencies, intra-day concentration changes and enantiomeric profiles during wastewater treatment were further analyzed. Loads of these two chiral pharmaceuticals were also studied to reveal drug use pattern. A/A/O+MBR (anaerobic/anoxic/oxic + membrane bio-reactor) followed by joint disinfection treatment process exhibited the high removal efficiencies. No or weak enantioselectivity was observed in most WWTPs. However, obvious enantiomeric fraction (EF) changing of MTP was observed in WWTP3 employing A/A/O+MBR. Intra-day concentration fluctuations of MTP were smaller than VFX. A quick response to sudden rise influent concentration of MTP was observed in WWTP1 effluent but EF response lagged behind. Similar bihourly EF variations in influents and effluents were also observed in most WWTPs for MTP and VFX in consideration of hydraulic residence time (HRT). [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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