التفاصيل البيبلوغرافية
| العنوان: |
Universitat Autonoma de Barcelona Reports Findings in Cardiovascular Research [Asymmetric Myocardial Involvement as an Early Indicator of Cardiac Dysfunction in Pediatric Dystrophinopathies: A Study on Cardiac Magnetic Resonance (CMR) Parametric...]. |
| المصدر: |
Pediatrics Week; 5/17/2024, p424-424, 1p |
| مصطلحات موضوعية: |
CARDIAC magnetic resonance imaging, HEART diseases, BECKER muscular dystrophy, PEDIATRIC cardiology, VENTRICULAR septum |
| مصطلحات جغرافية: |
BARCELONA (Spain) |
| مستخلص: |
A recent study conducted by researchers at the Universitat Autonoma de Barcelona in Spain explores the use of cardiac magnetic resonance (CMR) parametric mappings for early detection of myocardial involvement in pediatric dystrophinopathies, such as Duchenne and Becker muscular dystrophy. The study found that CMR mappings, specifically native T1 (nT1) and extracellular volume (ECV), showed significant variations in patients with dystrophinopathies compared to a control group. While higher mapping values did not directly correlate with dysfunction, there was a significant negative correlation between asymmetric involvement in nT1 and ECV with left ventricular ejection fraction (LVEF), suggesting their potential as early biomarkers. The researchers concluded that larger, longitudinal studies are needed to further understand and improve risk stratification in dystrophinopathies. [Extracted from the article] |
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| قاعدة البيانات: |
Complementary Index |
