التفاصيل البيبلوغرافية
| العنوان: |
Role of Dual-Acquisition Noninvasive Cardiac CT Imaging for the Detection of Vasospastic Angina. |
| المؤلفون: |
Jin, Xuan1,2 (AUTHOR) xuan880819@126.com, Kang, Eun-Ju3 (AUTHOR) medcarrot@dau.ac.kr, Jin, Cai-De1,4 (AUTHOR) jincaide1118@163.com, Lee, Kwang-Min1 (AUTHOR) tnt849@hanmail.net, Lim, Kyung-Hee1 (AUTHOR), Rha, Seung-Woon5 (AUTHOR) swrha617@yahoo.co.kr, Choi, Cheol-Ung5 (AUTHOR), Yong, Hwan-Seok6 (AUTHOR), Yun, Sung-Cheol7 (AUTHOR), Budoff, Matthew J.8 (AUTHOR), Yu, Long-Hao1,9 (AUTHOR), Kim, Moo-Hyun1 (AUTHOR) kimmh@dau.ac.kr |
| المصدر: |
Journal of Clinical Medicine. Jun2023, Vol. 12 Issue 11, p3753. 12p. |
| مصطلحات موضوعية: |
*COMPUTED tomography, *CARDIAC imaging, *ANGINA pectoris, *CORONARY angiography, *CORONARY artery disease |
| مصطلحات جغرافية: |
ASIA |
| مستخلص: |
Background: Vasospastic angina (VSA) is characterized by chest pain at rest with transient ischemic electrocardiographic changes in the ST segment, and a prompt response to nitrates. Vasospastic angina is among the most frequent of the coronary artery diseases in Asia, and coronary computed tomography angiography (CCTA) may become available as a non-invasive diagnosis method. Methods: We prospectively enrolled 100 patients with suspected vasospastic angina at two centers from 2018 to 2020. All patients underwent baseline CCTA without a vasodilator in the early morning followed by catheterized coronary angiography and spasm testing. CCTA with intravenous infusion of nitrate (IV) was repeated within 2 weeks of baseline CCTA. Vasospastic angina as detected by CCTA was defined as significant stenosis (≥50%) with negative remodeling without definite plaques or diffuse small diameter (<2 mm) of a major coronary artery with a beaded appearance on baseline CT that completely dilated on IV nitrate CT. We analyzed diagnostic performance of dual-acquisition CCTA for the detection of vasospastic angina. Results: The patients were categorized into three groups according to their provocation test result (negative, n = 36; probable positive, n = 18; positive, n = 31). The diagnostic accuracy in terms of CCTA per patient had a sensitivity of 55% (95% CI, 40–69), specificity of 89% (95% CI, 74–97), positive predictive value (PPV) of 87% (95% CI, 72–95), and negative predictive value (NPV) of 59% (95% CI, 51–67). Conclusions: Dual-acquisition CCTA can support the non-invasive detection of vasospastic angina with relatively good specificity and PPV. CCTA was helpful for non-invasive screening of variant angina. [ABSTRACT FROM AUTHOR] |
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