التفاصيل البيبلوغرافية
| العنوان: |
The Role of Thermal Effects in Plasma Medical Applications: Biological and Calorimetric Analysis |
| المؤلفون: |
Luigi Cordaro, Gianluca De Masi, Alessandro Fassina, Clarice Gareri, Antonio Pimazzoni, Daniele Desideri, Ciro Indolfi, Emilio Martines |
| المصدر: |
Applied Sciences; Volume 9; Issue 24; Pages: 5560 |
| بيانات النشر: |
Multidisciplinary Digital Publishing Institute |
| سنة النشر: |
2019 |
| المجموعة: |
MDPI Open Access Publishing |
| مصطلحات موضوعية: |
atmospheric pressure plasma jet (APPJ), cold atmospheric plasma (CAP), plasma medicine, blood coagulation, tissue damage |
| جغرافية الموضوع: |
agris |
| الوصف: |
Plasma Medicine tools exploit the therapeutic effects of the exposure of living matter to plasma produced at atmospheric pressure. Since these plasmas are usually characterized by a non-thermal equilibrium (highly energetic electrons, low temperature ions), thermal effects on the substrate are usually considered negligible. Conversely, reactive oxygen and nitrogen species (RONS), UV radiation and metastables are thought to play a major role. In this contribution, we compare the presence of thermal effects in different operational regimes (corresponding to different power levels) of the Plasma Coagulation Controller (PCC), a plasma source specifically designed for accelerating blood coagulation. In particular, we analyze the application of PCC on human blood samples (in vitro) and male Wistar rats tissues (in vivo). Histological analysis points out, for the highest applied power regime, the onset of detrimental thermal effects such as red cell lysis in blood samples and tissues damages in in-vivo experiments. Calorimetric bench tests performed on metallic targets show that the current coupled by the plasma on the substrate induces most of measured thermal loads through a resistive coupling. Furthermore, the distance between the PCC nozzle and the target is found to strongly affect the total power. |
| نوع الوثيقة: |
text |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
Applied Biosciences and Bioengineering; https://dx.doi.org/10.3390/app9245560Test |
| DOI: |
10.3390/app9245560 |
| الإتاحة: |
https://doi.org/10.3390/app9245560Test |
| حقوق: |
https://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: |
edsbas.33EC8F4E |
| قاعدة البيانات: |
BASE |
