التفاصيل البيبلوغرافية
| العنوان: |
Obesity and sex influence fatty infiltration of the rotator cuff: the Rotator Cuff Outcomes Workgroup (ROW) and Multicenter Orthopaedic Outcomes Network (MOON) cohorts |
| المؤلفون: |
Giri, Ayush, Freeman, Thomas H, Kim, Peter, Kuhn, John E, Garriga, Gustavo A, Khazzam, Michael, Higgins, Laurence D, Matzkin, Elizabeth, Baumgarten, Keith M, Bishop, Julie Y, Brophy, Robert H, Carey, James L, Dunn, Warren R, Jones, Grant L, Ma, C Benjamin, Marx, Robert G, McCarty, Eric C, Poddar, Sourav K, Smith, Matthew V, Spencer, Edwin E, Vidal, Armando F, Wolf, Brian R, Wright, Rick W, Jain, Nitin B |
| المصدر: |
Journal of Shoulder and Elbow Surgery, vol 31, iss 4 |
| بيانات النشر: |
eScholarship, University of California |
| سنة النشر: |
2022 |
| المجموعة: |
University of California: eScholarship |
| مصطلحات موضوعية: |
Nutrition, Obesity, Clinical Research, Prevention, Patient Safety, Adipose Tissue, Female, Humans, Male, Multicenter Studies as Topic, Orthopedics, Risk Factors, Rotator Cuff, Rotator Cuff Injuries, Sex Factors, fatty infiltration, body mass index, sex, cross-sectional study, Clinical Sciences |
| جغرافية الموضوع: |
726 - 735 |
| الوصف: |
BackgroundFatty infiltration (FI) is one of the most important prognostic factors for outcomes after rotator cuff surgery. Established risk factors include advancing age, larger tear size, and increased tear chronicity. A growing body of evidence suggests that sex and obesity are associated with FI; however, data are limited.MethodsWe recruited 2 well-characterized multicenter cohorts of patients with rotator cuff tears (Multicenter Orthopaedic Outcomes Network [MOON] cohort [n=80] and Rotator Cuff Outcomes Workgroup [ROW] cohort [n=158]). We used multivariable logistic regression to evaluate the relationship between body mass index (BMI) and the presence of FI while adjusting for the participant's age at magnetic resonance imaging, sex, and duration of shoulder symptoms, as well as the cross-sectional area of the tear. We analyzed the 2 cohorts separately and performed a meta-analysis to combine estimates.ResultsA total of 27 patients (33.8%) in the Multicenter Orthopaedic Outcomes Network (MOON) cohort and 57 patients (36.1%) in the Rotator Cuff Outcomes Workgroup (ROW) cohort had FI. When BMI < 25 kg/m2 was used as the reference category, being overweight was associated with a 2.37-fold (95% confidence interval [CI], 0.77-7.29) increased odds of FI and being obese was associated with a 3.28-fold (95% CI, 1.16-9.25) increased odds of FI. Women were 4.9 times (95% CI, 2.06-11.69) as likely to have FI as men.ConclusionsAmong patients with rotator cuff tears, obese patients had a substantially higher likelihood of FI. Further research is needed to assess whether modifying BMI can alter FI in patients with rotator cuff tears. This may have significant clinical implications for presurgical surgical management of rotator cuff tears. Sex was also significantly associated with FI, with women having higher odds of FI than men. Higher odds of FI in female patients may also explain previously reported early suboptimal outcomes of rotator cuff surgery and higher pain levels in female patients as compared with male ... |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
unknown |
| العلاقة: |
qt1fc7x0k1; https://escholarship.org/uc/item/1fc7x0k1Test |
| الإتاحة: |
https://escholarship.org/uc/item/1fc7x0k1Test |
| حقوق: |
public |
| رقم الانضمام: |
edsbas.43A18A08 |
| قاعدة البيانات: |
BASE |
