التفاصيل البيبلوغرافية
| العنوان: |
Smoking-related idiopathic interstitial pneumonia |
| المؤلفون: |
Flaherty, Kevin R, Fell, Charlene, Aubry, Marie-Christine, Brown, Kevin, Colby, Thomas, Costabel, Ulrich, Franks, Teri J, Gross, Barry H, Hansell, David M, Kazerooni, Ella, Kim, Dong Soon, King, Talmadge E, Kitachi, Masanori, Lynch, David, Myers, Jeff, Nagai, Sonoko, Nicholson, Andrew G, Poletti, Venerino, Raghu, Ganesh, Selman, Moises, Toews, Galen, Travis, William, Wells, Athol U, Vassallo, Robert, Martinez, Fernando J |
| المصدر: |
European Respiratory Journal, vol 44, iss 3 |
| بيانات النشر: |
eScholarship, University of California |
| سنة النشر: |
2014 |
| المجموعة: |
University of California: eScholarship |
| مصطلحات موضوعية: |
Biomedical and Clinical Sciences, Clinical Sciences, Lung, Pneumonia & Influenza, Clinical Research, Tobacco Smoke and Health, Prevention, Tobacco, Infectious Diseases, Clinical Trials and Supportive Activities, Pneumonia, Respiratory, Adult, Aged, Carbon Monoxide, Female, Humans, Idiopathic Interstitial Pneumonias, International Cooperation, Male, Mental Recall, Mexico, Middle Aged, Models, Organizational, Prognosis, Pulmonary Medicine, Radiology, Republic of Korea, Retrospective Studies |
| جغرافية الموضوع: |
594 - 602 |
| الوصف: |
Cigarette smoking is a key factor in the development of numerous pulmonary diseases. An international group of clinicians, radiologists and pathologists evaluated patients with previously identified idiopathic interstitial pneumonia (IIP) to determine unique features of cigarette smoking. Phase 1 (derivation group) identified smoking-related features in patients with a history of smoking (n=41). Phase 2 (validation group) determined if these features correctly predicted the smoking status of IIP patients (n=100) to participants blinded to smoking history. Finally, the investigators sought to determine if a new smoking-related interstitial lung disease phenotype could be defined. Phase 1 suggested that preserved forced vital capacity with disproportionately reduced diffusing capacity of the lung for carbon monoxide, and various radiographic and histopathological findings were smoking-related features. In phase 2, the kappa coefficient among clinicians was 0.16 (95% CI 0.11-0.21), among the pathologists 0.36 (95% CI 0.32-0.40) and among the radiologists 0.43 (95% CI 0.35-0.52) for smoking-related features. Eight of the 100 cases were felt to represent a potential smoking-related interstitial lung disease. Smoking-related features of interstitial lung disease were identified in a minority of smokers and were not specific for smoking. This study is limited by its retrospective design, the potential for recall bias in smoking history and lack of information on second-hand smoke exposure. Further research is needed to understand the relationship between smoking and interstitial lung disease. |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
unknown |
| العلاقة: |
qt81h0b8cn; https://escholarship.org/uc/item/81h0b8cnTest |
| الإتاحة: |
https://escholarship.org/uc/item/81h0b8cnTest |
| حقوق: |
public |
| رقم الانضمام: |
edsbas.60C14AE7 |
| قاعدة البيانات: |
BASE |
