دورية أكاديمية
A Comparison of the Oral Microbiota in Healthy Dogs and Dogs with Oral Tumors
| العنوان: | A Comparison of the Oral Microbiota in Healthy Dogs and Dogs with Oral Tumors |
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| المؤلفون: | Anja Lisjak, Bruna Correa Lopes, Rachel Pilla, Ana Nemec, Jan S. Suchodolski, Nataša Tozon |
| المصدر: | Animals, Vol 13, Iss 23, p 3594 (2023) |
| بيانات النشر: | MDPI AG, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Veterinary medicine LCC:Zoology |
| مصطلحات موضوعية: | oral microbiota, DNA shotgun sequencing, oral tumors, oral swab, biopsy, dogs, Veterinary medicine, SF600-1100, Zoology, QL1-991 |
| الوصف: | The aim of this study was to further describe the oral microbiota of healthy dogs by DNA shotgun sequencing and compare those to dogs with oral tumors. Oral swabs (representative of all niches of the oral cavity) were collected from healthy dogs (n = 24) and from dogs with different oral tumors (n = 7). DNA was extracted from the swabs and shotgun metagenomic sequencing was performed. Only minor differences in microbiota composition were observed between the two groups. At the phylum level, the Bacteroidota, Proteobacteria, Actinobacteriota, Desulfobacterota and Firmicutes were most abundant in both groups. Observed Operational Taxonomic Units—OTUs (species richness) was significantly higher in the healthy patients, but there was no significant difference in the Shannon diversity index between the groups. No significant difference was found in beta diversity between the groups. The core oral microbiota consisted of 67 bacterial species that were identified in all 24 healthy dogs. Our study provides further insight into the composition of the oral microbiota of healthy dogs and in dogs with oral tumors. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2076-2615 |
| العلاقة: | https://www.mdpi.com/2076-2615/13/23/3594Test; https://doaj.org/toc/2076-2615Test |
| DOI: | 10.3390/ani13233594 |
| الوصول الحر: | https://doaj.org/article/ad4d6cd550c84fc8a210c92a38017964Test |
| رقم الانضمام: | edsdoj.4d6cd550c84fc8a210c92a38017964 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20762615 |
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| DOI: | 10.3390/ani13233594 |