نتائج البحث - "Frank W.G. Leebeek"

1

Thrombin generation is associated with ischemic stroke at a young age

المؤلفون: Hugo ten Cate, Moniek P.M. de Maat, Diederik W.J. Dippel, Samantha J. Donkel, Frank W.G. Leebeek, Karmen Pater

المساهمون: Hematology, Neurology, Interne Geneeskunde, MUMC+: HVC Trombosezorg (8), MUMC+: MA Alg Interne Geneeskunde (9), MUMC+: HVC Pieken Trombose (9), RS: Carim - B04 Clinical thrombosis and Haemostasis

المصدر: Thrombosis Research, 202, 139-144. Elsevier Ltd.
Thrombosis Research, 202, 139-144. Elsevier Science

مصطلحات موضوعية: Thrombin generation, medicine.medical_specialty, Percentile, Young, 030204 cardiovascular system & hematology, Logistic regression, Gastroenterology, HYPERCOAGULABILITY, PLATELET-RICH PLASMA, MECHANISMS, Brain Ischemia, Transient ischemic attack (TIA), 03 medical and health sciences, 0302 clinical medicine, Thrombin, Internal medicine, medicine, Humans, Prospective Studies, Young adult, THROMBOGRAM, Prospective cohort study, MUTATION, Ischemic Stroke, RISK, business.industry, ADULTS, Hematology, Odds ratio, medicine.disease, Confidence interval, Stroke, ATHEROSCLEROSIS, CARDIOVASCULAR-DISEASE, Case-Control Studies, 030220 oncology & carcinogenesis, business, Case-controls studies, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a2a6030cec741d8e15795103aee5f3Test
https://doi.org/10.1016/j.thromres.2021.03.028Test

2

In silico comparison of pharmacokinetic properties of three extended half-life factor IX concentrates

المؤلفون: Max W. F. van Spengler, Laura H. Bukkems, Ron A. A. Mathôt, Tim Preijers, Marjon H. Cnossen, Frank W.G. Leebeek

المساهمون: Pediatrics, Hematology, Graduate School, Pharmacy, Other Research, Amsterdam Gastroenterology Endocrinology Metabolism

المصدر: European Journal of Clinical Pharmacology
European Journal of Clinical Pharmacology, 77(8), 1193-1200. Springer-Verlag
European journal of clinical pharmacology, 77(8), 1193-1200. Springer Verlag

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0db90802c517ab0964ff4f2d73cf9ec9Test
https://doi.org/10.1007/s00228-021-03111-2Test

3

Population Pharmacokinetic Modeling of von Willebrand Factor Activity in von Willebrand Disease Patients after Desmopressin Administration

المؤلفون: Marjon H. Cnossen, Jessica M. Heijdra, Quincy Kieboom, Frank W.G. Leebeek, Nico C B de Jager, Marieke J. H. A. Kruip, Ron A. A. Mathôt

المساهمون: Graduate School, Amsterdam Gastroenterology Endocrinology Metabolism, Pharmacy, ACS - Pulmonary hypertension & thrombosis, Hematology, Pediatrics

المصدر: Thrombosis and haemostasis, 120(10), 1407-1416. Schattauer GmbH
Thrombosis and Haemostasis, 120(10), 1407-1416. Georg Thieme Verlag

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, Adolescent, Population, empirical PK, 030204 cardiovascular system & hematology, Models, Biological, Gastroenterology, Hemostatics, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Von Willebrand factor, Pharmacokinetics, Internal medicine, hemic and lymphatic diseases, von Willebrand Factor, medicine, Von Willebrand disease, Humans, Deamino Arginine Vasopressin, Dosing, desmopressin response, Child, Desmopressin, education, Aged, Volume of distribution, education.field_of_study, biology, business.industry, Hematology, Middle Aged, medicine.disease, Bioavailability, von Willebrand Diseases, 030104 developmental biology, Child, Preschool, biology.protein, Female, business, von Willebrand disease, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0fe40dd543c5765c901bb870f73199bTest
http://www.scopus.com/inward/record.url?scp=85089861052&partnerID=8YFLogxKTest

4

The one-stage assay or chromogenic assay to monitor baseline factor VIII levels and desmopressin effect in non-severe haemophilia A: Superiority or non-inferiority?

المؤلفون: Marieke J. H. A. Kruip, Luca S Hodes, Iris van Moort, Moniek P.M. de Maat, Sara C. M. Stoof, Lisette M. Schütte, Frank W.G. Leebeek, Marjon H. Cnossen

المساهمون: Hematology, Pediatrics

المصدر: Haemophilia, 26(5), 916-922. Wiley-Blackwell Publishing Ltd
Haemophilia

مصطلحات موضوعية: Adult, Male, desmopressin, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, Adolescent, Haemophilia A, haemophilia A, 030204 cardiovascular system & hematology, Hemophilia A, Gastroenterology, Young Adult, 03 medical and health sciences, chromogenic assay, 0302 clinical medicine, Non inferiority, hemic and lymphatic diseases, Internal medicine, medicine, Humans, Outpatient clinic, Deamino Arginine Vasopressin, one‐stage assay, Desmopressin, Genetics (clinical), Aged, Retrospective Studies, Aged, 80 and over, Factor VIII, business.industry, Chromogenic, One stage, Original Articles, Hematology, General Medicine, Factor VIII Activity, Middle Aged, medicine.disease, Laboratory Science, bleeding phenotype, Original Article, Severe haemophilia A, business, 030215 immunology, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eee7dfef38a887fd6a8e093240acaeb6Test
https://doi.org/10.1111/hae.14106Test

5

Current dosing practices for perioperative factor VIII concentrate treatment in mild haemophilia A patients result in FVIII levels above target

المؤلفون: Nils de Rooij, Hendrika C A M Hazendonk, Reinier M. van Hest, Marjon H. Cnossen, Lisette M. Schütte, Ron A. A. Mathôt, Marieke J. H. A. Kruip, Frank W.G. Leebeek

المساهمون: Pharmacy, AGEM - Endocrinology, metabolism and nutrition, AGEM - Digestive immunity, AII - Inflammatory diseases, ACS - Pulmonary hypertension & thrombosis, Hematology, Pediatrics

المصدر: Haemophilia. Wiley-Blackwell
Haemophilia, 25(6). Wiley-Blackwell Publishing Ltd

مصطلحات موضوعية: Adult, Male, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, Adolescent, animal diseases, Haemophilia A, 030204 cardiovascular system & hematology, Hemophilia A, Target range, Body weight, Gastroenterology, Young Adult, 03 medical and health sciences, 0302 clinical medicine, hemic and lymphatic diseases, Internal medicine, medicine, Humans, In patient, Dosing, Child, Perioperative Period, Genetics (clinical), Aged, Retrospective Studies, Factor VIII, Dose-Response Relationship, Drug, business.industry, Dosing regimen, Hematology, General Medicine, Perioperative, Middle Aged, medicine.disease, Treatment Outcome, Child, Preschool, Mild haemophilia A, Female, business, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::342b66fcf19b13f5978557795f304e50Test
https://doi.org/10.1111/hae.13838Test

6

Dosing of factor VIII concentrate by ideal body weight is more accurate in overweight and obese haemophilia A patients

المؤلفون: Hendrika C A M Hazendonk, Tim Preijers, Frank W.G. Leebeek, R. A. A. Mathôt, Felix J. M. van der Meer, Iris van Moort, Britta A P Laros-van Gorkom, Marjon H. Cnossen, Laurens Nieuwenhuizen, Karina Meijer, Karin Fijnvandraat, Roger E. G. Schutgens

المساهمون: Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Pediatrics, Hematology, Graduate School, Amsterdam Gastroenterology Endocrinology Metabolism, Paediatric Haematology, Amsterdam Reproduction & Development (AR&D), Pharmacy

المصدر: British Journal of Clinical Pharmacology, 87(6), 2602-2613. Wiley
British Journal of Clinical Pharmacology, 87, 2602-2613
British Journal of Clinical Pharmacology, 87(6), 2602-2613. Wiley-Blackwell Publishing Ltd
British journal of clinical pharmacology, 87(6), 2602-2613. Wiley-Blackwell
British Journal of Clinical Pharmacology, 87, 6, pp. 2602-2613
British Journal of Clinical Pharmacology

مصطلحات موضوعية: obesity, PHARMACOKINETICS, CLEARANCE, Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], Ideal Body Weight, CHILDREN, Overweight, 030226 pharmacology & pharmacy, Gastroenterology, 0302 clinical medicine, hemic and lymphatic diseases, Pharmacology (medical), 030212 general & internal medicine, INDEX, Volume of distribution, education.field_of_study, Middle Aged, modelling and simulation, Original Article, medicine.symptom, Adult, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, Adolescent, VON-WILLEBRAND-FACTOR, Population, Haemophilia A, RECOMBINANT FACTOR-VIII, MASS, Hemophilia A, Young Adult, 03 medical and health sciences, AGE, Pharmacokinetics, Internal medicine, medicine, Humans, Dosing, education, Aged, Pharmacology, Factor VIII, business.industry, Original Articles, medicine.disease, Obesity, SIZE, haemostasis, business, Body mass index

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45ce2ecb1ea7f2d1442bad3d0e357fdaTest
https://research.rug.nl/en/publications/b785c50f-97d8-4f39-b173-ebc413b6381bTest

7

Outcome of Surgical Interventions and Deliveries in Patients with Bleeding of Unknown Cause: An Observational Study

المؤلفون: Marieke J. H. A. Kruip, Marjon H. Cnossen, Celesta W. A. Schipaanboord, Lorenzo G. R. Romano, Elise J. Huisman, Frank W.G. Leebeek, Caroline S B Veen, Moniek P.M. de Maat

المساهمون: Hematology, Pediatrics

المصدر: Thrombosis and Haemostasis, 121(11), 1409-1416. Georg Thieme Verlag

مصطلحات موضوعية: Adult, medicine.medical_specialty, Adolescent, Blood Loss, Surgical, Platelet Transfusion, 030204 cardiovascular system & hematology, Postoperative Hemorrhage, Hemorrhagic Disorders, Risk Assessment, Drug Administration Schedule, Hemostatics, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Blood Coagulation Disorders, Inherited, Pregnancy, Risk Factors, Medicine, Humans, In patient, Child, Retrospective Studies, business.industry, Postpartum Hemorrhage, Hematology, Perioperative, Surgical procedures, Blood Coagulation Disorders, Delivery, Obstetric, Optimal management, Surgery, Pregnancy Complications, Treatment Outcome, Hemostasis, Observational study, Female, business, Surgical interventions, Major bleeding, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ba3fc77520780559a7a4e7d902de964Test
https://pubmed.ncbi.nlm.nih.gov/33853179Test

8

A Novel, Enriched Population Pharmacokinetic Model for Recombinant Factor VIII-Fc Fusion Protein Concentrate in Hemophilia A Patients

المساهمون: Pediatrics, Hematology, Graduate School, Pharmacy, Other Research, Paediatric Haematology, AGEM - Digestive immunity, AGEM - Endocrinology, metabolism and nutrition, ARD - Amsterdam Reproduction and Development, Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET)

المصدر: Thrombosis and Haemostasis, 120(5), 747-757. Georg Thieme Verlag
Thrombosis and haemostasis, 120(5), 747-757. Schattauer GmbH
Thrombosis and Haemostasis, 120(5), 747-757. GEORG THIEME VERLAG KG

مصطلحات موضوعية: 0301 basic medicine, Male, SAMPLES, population, 030204 cardiovascular system & hematology, Hemostatics, 0302 clinical medicine, STAGE, Medicine, Registries, Child, Factor IX, Netherlands, validation, education.field_of_study, PLASMA, Age Factors, Hematology, Middle Aged, Mean absolute percentage error, recombinant factor VIII-Fc, pharmacokinetics, medicine.drug, Adult, medicine.medical_specialty, Adolescent, VON-WILLEBRAND-FACTOR, Recombinant Fusion Proteins, Population, Hemophilia A, Recombinant factor viii, Models, Biological, 03 medical and health sciences, Young Adult, AGE, Pharmacokinetics, Internal medicine, Humans, Dosing, education, Aged, Factor VIII, business.industry, Reproducibility of Results, FACTOR-IX, United Kingdom, NONMEM, Immunoglobulin Fc Fragments, Clinical trial, 030104 developmental biology, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2725ef1b451329b318ac247f4e9fa808Test
https://pure.eur.nl/en/publications/ab0d2602-2004-4fbd-a4b7-d10d7bf577caTest

9

Circulating Angiogenic Mediators in Patients with Moderate and Severe von Willebrand Disease: A Multicentre Cross-Sectional Study

المؤلفون: Jelle Adelmeijer, Jeroen Eikenboom, Johanna G. van der Bom, Y V Sanders, Evelien P. Mauser-Bunschoten, Karina Meijer, Karin Fijnvandraat, Frank W.G. Leebeek, Britta A P Laros-van Gorkom, Marjon H. Cnossen, Dafna J. Groeneveld, Ton Lisman

المساهمون: ACS - Amsterdam Cardiovascular Sciences, Paediatric Infectious Diseases / Rheumatology / Immunology, ACS - Pulmonary hypertension & thrombosis, Groningen Institute for Organ Transplantation (GIOT), Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Hematology, Pediatrics

المصدر: Thrombosis and Haemostasis
Thrombosis and Haemostasis, 118, 152-160
Thrombosis and haemostasis, 118(1), 152-160. Schattauer GmbH
Thrombosis and Haemostasis, 118, 1, pp. 152-160
Thrombosis and Haemostasis, 118(1), 152-160. GEORG THIEME VERLAG KG
Thrombosis and Haemostasis, 118(1), 152-160. Georg Thieme Verlag

مصطلحات موضوعية: Male, Vascular Endothelial Growth Factor A, 0301 basic medicine, Angiogenesis, Galectin 3, Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], 030204 cardiovascular system & hematology, Pathogenesis, chemistry.chemical_compound, 0302 clinical medicine, hemic and lymphatic diseases, WEIBEL-PALADE BODIES, Child, Netherlands, Aged, 80 and over, Neovascularization, Pathologic, biology, Blood Proteins, Hematology, Middle Aged, ANGIODYSPLASIA, VEGF, Vascular endothelial growth factor, von Willebrand Diseases, Vascular endothelial growth factor A, Child, Preschool, cardiovascular system, Female, Gastrointestinal Hemorrhage, circulatory and respiratory physiology, Adult, EXPRESSION, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, Adolescent, Galectins, Young Adult, 03 medical and health sciences, All institutes and research themes of the Radboud University Medical Center, Von Willebrand factor, Osteoprotegerin, Internal medicine, von Willebrand Factor, Angiopoietin-1, Journal Article, medicine, Weibel–Palade body, Von Willebrand disease, Humans, Aged, GALECTIN-3, OSTEOPROTEGERIN, business.industry, Endothelial Cells, Infant, FACTOR PROPEPTIDE, medicine.disease, Cross-Sectional Studies, 030104 developmental biology, Endocrinology, Gene Expression Regulation, chemistry, ENDOTHELIAL GROWTH-FACTOR, ANGIOPOIETIN-2, CELLS, biology.protein, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eed2f5d189299ab2c8d26c2c78671f9fTest
https://doi.org/10.1160/th17-06-0397Test

10

Positioning extended half-life concentrates for future use: a practical proposal

المؤلفون: Karin Fijnvandraat, Angelique Nederlof, Ron A. A. Mathôt, Frank W.G. Leebeek, Krista Fischer, Marjon H. Cnossen

المساهمون: AGEM - Digestive immunity, Pharmacy, AGEM - Endocrinology, metabolism and nutrition, ACS - Pulmonary hypertension & thrombosis, Paediatric Infectious Diseases / Rheumatology / Immunology, Pediatrics, Hematology

المصدر: Haemophilia, 24(5), e369-e372. Wiley-Blackwell
Haemophilia, 24(5), E369-E372. Wiley-Blackwell Publishing Ltd
Haemophilia, 24(5), e369. Wiley-Blackwell

وصف الملف: image/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c8ae66c38a7ac251726b188be9add8Test
https://doi.org/10.1111/hae.13588Test

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