المؤلفون: Amani Makkouk, Xue (Cher) Yang, Taylor Barca, Anthony Lucas, Mustafa Turkoz, Jonathan T S Wong, Kevin P Nishimoto, Mary M Brodey, Maryam Tabrizizad, Smitha R Y Gundurao, Lu Bai, Arun Bhat, Zili An, Stewart Abbot, Daulet Satpayev, Blake T Aftab, Marissa Herrman

المصدر: Journal for Immunotherapy of Cancer

مصطلحات موضوعية: Cancer Research, Carcinoma, Hepatocellular, T-Lymphocytes, Immunology, Apoptosis, Mice, SCID, cell engineering, adoptive, Immunotherapy, Adoptive, Mice, Glypicans, Mice, Inbred NOD, innate, Tumor Cells, Cultured, tumor microenvironment, Animals, Humans, Immunology and Allergy, Cell Proliferation, Interleukin-15, Pharmacology, Receptors, Chimeric Antigen, Immune Cell Therapies and Immune Cell Engineering, Liver Neoplasms, Receptors, Antigen, T-Cell, gamma-delta, immunity, Xenograft Model Antitumor Assays, Oncology, Leukocytes, Mononuclear, Molecular Medicine, Female, immunotherapy

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e955ee28a80f5478bb3fb0c7d714e4Test
https://doi.org/10.1136/jitc-2021-003441Test

المؤلفون: Hui Liu, Yu Hsiu T. Lin, Megan Murnane, Geoffrey A. Smith, Christine Lam, Margarette C. Mariano, Arun P. Wiita, Jack Taunton, Sandy W. Wong, Jun O. Liu, Constantine S. Mitsiades, Blake T. Aftab, Ian Ferguson, Byron Hann

المصدر: Haematologica, vol 103, iss 7
Haematologica

مصطلحات موضوعية: 0301 basic medicine, Proteomics, Ruxolitinib, Proteome, Cell Communication, Cardiorespiratory Medicine and Haematology, Plasma Cell Disorders, chemistry.chemical_compound, Mice, Piperidines, Bone Marrow, Tumor Microenvironment, 2.1 Biological and endogenous factors, Medicine, Aetiology, Cancer, Hematology, 3. Good health, STAT Transcription Factors, medicine.anatomical_structure, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Multiple Myeloma, medicine.drug, Signal Transduction, Stromal cell, Plasma Cells, Immunology, Article, 03 medical and health sciences, Rare Diseases, In vivo, Animals, Humans, Pyrroles, Protein Kinase Inhibitors, Janus Kinases, Tumor microenvironment, Tofacitinib, 5.2 Cellular and gene therapies, business.industry, Venetoclax, Animal, Mesenchymal stem cell, Drug Repositioning, Mesenchymal Stem Cells, Phosphoproteins, Xenograft Model Antitumor Assays, Disease Models, Animal, Orphan Drug, 030104 developmental biology, Pyrimidines, chemistry, Disease Models, Cancer research, Bone marrow, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d3bb91b64a9c4e0fbaed43ab5969e84Test
https://escholarship.org/uc/item/99g7601fTest

المؤلفون: P. Leif Bergsagel, Marta Chesi, Marianne Kraus, Christoph Driessen, Laura K. Shawver, Grace J. Lee, Blake T. Aftab, Szerenke Kiss von Soly, Mark Rolfe, Megan Murnane, Ronan Le Moigne, Jinhai Wang, Daniel Anderson, Jeffrey L. Wolf, Arun P. Wiita, Mary Kamala Menon, Emily M. King, Stevan Djakovic, David J. Wustrow, Ferdie Soriano, Constantine S. Mitsiades, Han Jie Zhou, Eduardo Valle, Stephen T. C. Wong, Thomas G. Martin, Zhi Yong Wu, Eugen Dhimolea, Christine Lam, F. Michael Yakes, Julie Rice, Bing Yao

المصدر: Molecular cancer therapeutics. 16(11)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Proteasome Endopeptidase Complex, Indoles, Apoptosis, Biology, 03 medical and health sciences, Mice, 0302 clinical medicine, Ubiquitin, P97 Inhibitor CB-5083, medicine, Animals, Humans, Nuclear protein, Multiple myeloma, Cell Proliferation, Adenosine Triphosphatases, Cell growth, Nuclear Respiratory Factor 1, Nuclear Proteins, medicine.disease, Xenograft Model Antitumor Assays, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Pyrimidines, Oncology, Proteasome, 030220 oncology & carcinogenesis, Unfolded protein response, Cancer research, biology.protein, Proteasome inhibitor, Unfolded Protein Response, Multiple Myeloma, Proteasome Inhibitors, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdabd665906a2c466a4f478c5ace23bbTest
https://pubmed.ncbi.nlm.nih.gov/28878026Test

المؤلفون: Peter Walter, Xiaobo Wu, Daniel W. Sherbenou, Bin Liu, Blake T. Aftab, Diego Acosta-Alvear, Thomas G. Martin, Aaron C Logan, Yang Su, Byron Hann, Marc A. Shuman, John P. Atkinson, Jeffrey L. Wolf, Arun P. Wiita, Christopher R. Behrens

المصدر: The Journal of clinical investigation, vol 126, iss 12

مصطلحات موضوعية: 0301 basic medicine, Immunoconjugates, Antibodies, Neoplasm, viruses, Cell, Gene Dosage, Medical and Health Sciences, Mice, Monoclonal, Multiple myeloma, Cancer, Tumor, biology, Antibodies, Monoclonal, General Medicine, Hematology, female genital diseases and pregnancy complications, 3. Good health, medicine.anatomical_structure, 5.1 Pharmaceuticals, Chromosomes, Human, Pair 1, Pair 1, Antibody, Development of treatments and therapeutic interventions, Multiple Myeloma, Human, Biotechnology, Research Article, Antibody-drug conjugate, medicine.drug_class, Immunology, Monoclonal antibody, Chromosomes, Antibodies, Cell Line, Membrane Cofactor Protein, 03 medical and health sciences, Rare Diseases, Clinical Research, Cell Line, Tumor, medicine, Genetics, Animals, Humans, Innate immune system, business.industry, medicine.disease, Xenograft Model Antitumor Assays, 030104 developmental biology, Cell culture, biology.protein, Cancer research, Neoplasm, Bone marrow, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4493ea8c812dbe33beb060ad3da7b1b3Test
https://europepmc.org/articles/PMC5127683Test/

المؤلفون: Sanh Tan Lam, Edna F. Choo, Lillian Lee, Harvey Wong, Amy C. Peterson, Congfen Li, Yongchang Shi, Klaus P. Hoeflich, John Prescott, Geoffrey Del Rosario, Marcia Belvin, Jean-Francois Martini, Ron Aoyama, Peiwen Yu, Joeseph A Ware, Blake T. Aftab, Laurent Vernillet

المصدر: Clinical Cancer Research. 18:3090-3099

مصطلحات موضوعية: MAPK/ERK pathway, Cancer Research, Population, Mice, Nude, Antineoplastic Agents, Pharmacology, Models, Biological, Mice, Piperidines, Pharmacokinetics, In vivo, Cell Line, Tumor, Animals, Humans, Medicine, Potency, education, Protein Kinase Inhibitors, Mitogen-Activated Protein Kinase Kinases, education.field_of_study, business.industry, MEK inhibitor, Melanoma, medicine.disease, Xenograft Model Antitumor Assays, Oncology, Pharmacodynamics, Azetidines, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afddce05a73ecd664670ea98a745ceb1Test
https://doi.org/10.1158/1078-0432.ccr-12-0445Test

المؤلفون: Steve Wong, Jinhai Wang, Laura K. Shawver, Szerenke Kiss von Soly, Mark Rolfe, Julie Rice, Bing Yao, Brajesh Kumar, Martin Kampmann, Daniel Anderson, Eduardo Valle, Blake T. Aftab, Ronan Le Moigne, F. Michael Yakes, Zhi Yong Wu, Mary-Kamala Menon, Jonathan S. Weissman, Antonett Madriaga, Stevan Djakovic, Ferdie Soriano, Han-Jie Zhou, Yuwen Chen, David J. Wustrow

المصدر: Cancer cell, vol 28, iss 5

مصطلحات موضوعية: Cancer Research, Indoles, Nude, Apoptosis, Mice, SCID, Mice, 0302 clinical medicine, Neoplasms, Homeostasis, 2.1 Biological and endogenous factors, Molecular Targeted Therapy, Nuclear protein, Enzyme Inhibitors, Aetiology, Cancer, Regulation of gene expression, Adenosine Triphosphatases, 0303 health sciences, Tumor, Molecular Structure, Blotting, Reverse Transcriptase Polymerase Chain Reaction, Nuclear Proteins, Endoplasmic Reticulum-Associated Degradation, Ubiquitinated Proteins, AAA proteins, 3. Good health, Cell biology, Gene Expression Regulation, Neoplastic, Oncology, 030220 oncology & carcinogenesis, RNA Interference, Western, Biotechnology, Blotting, Western, Oncology and Carcinogenesis, Mice, Nude, Biology, Endoplasmic-reticulum-associated protein degradation, SCID, Article, Cell Line, 03 medical and health sciences, Cell Line, Tumor, Genetics, ERAD pathway, Animals, Humans, Oncology & Carcinogenesis, 030304 developmental biology, Neoplastic, Endoplasmic reticulum, HEK 293 cells, Neurosciences, Cell Biology, HCT116 Cells, Xenograft Model Antitumor Assays, Pyrimidines, HEK293 Cells, Gene Expression Regulation, Unfolded protein response, CRISPR-Cas Systems, K562 Cells

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8c0010f90064594c471ccfefe9d9d4dTest
https://escholarship.org/uc/item/1mg4031wTest

المؤلفون: Charles M. Rudin, Jun O. Liu, Blake T. Aftab, Irina Dobromilskaya

المصدر: Cancer Research. 71:6764-6772

مصطلحات موضوعية: Cancer Research, Lung Neoplasms, Bevacizumab, Angiogenesis, Itraconazole, Antifungal drug, Angiogenesis Inhibitors, Antineoplastic Agents, Mice, SCID, Adenocarcinoma, Pharmacology, Biology, Article, Neovascularization, Mice, Cell Movement, Mice, Inbred NOD, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Antineoplastic Combined Chemotherapy Protocols, medicine, Animals, Humans, Lung cancer, Cells, Cultured, Aged, Tube formation, Dose-Response Relationship, Drug, Neovascularization, Pathologic, Endothelial Cells, Cancer, Hypoxia-Inducible Factor 1, alpha Subunit, medicine.disease, Xenograft Model Antitumor Assays, Oncology, Carcinoma, Squamous Cell, Intercellular Signaling Peptides and Proteins, Cisplatin, Drug Screening Assays, Antitumor, medicine.symptom, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b030299e6434523fc10f0bbcf18a80Test
https://doi.org/10.1158/0008-5472.can-11-0691Test

المؤلفون: Dipankar Pramanik, Saeed R. Khan, Ming Zhao, Venugopal Chenna, Chaoxin Hu, Collins Karikari, Michelle A. Rudek, Seung-Mo Hong, Nathaniel R. Campbell, Charles M. Rudin, Anirban Maitra, Blake T. Aftab

المصدر: Molecular cancer therapeutics. 11(1)

مصطلحات موضوعية: Male, Patched Receptors, Cancer Research, Mice, Nude, Receptors, Cell Surface, Biology, Deoxycytidine, Zinc Finger Protein GLI1, Article, Receptors, G-Protein-Coupled, Mice, Downregulation and upregulation, GLI1, Cell Line, Tumor, Animals, Humans, Hedgehog Proteins, Cell Proliferation, Cell growth, Smoothened Receptor, Xenograft Model Antitumor Assays, Gemcitabine, Hedgehog signaling pathway, Pancreatic Neoplasms, Patched-1 Receptor, Oncology, Biochemistry, biology.protein, Cancer research, Systemic administration, Nanoparticles, Signal transduction, Tumor Suppressor Protein p53, Smoothened, Medulloblastoma, Signal Transduction, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333a813f2897d579f3402dae5ed50a88Test
https://pubmed.ncbi.nlm.nih.gov/22027695Test