المؤلفون: Thompson, Alex¹, Devine, Scott² scott.devine@gmail.com, Kattan, Mike³, Muir, Andrew⁴

المصدر: PLoS ONE. Aug2014, Vol. 9 Issue 8, p1-8. 8p.

مصطلحات موضوعية: *VIRAL disease treatment, *BOCEPREVIR, *VIRUS diseases, *PREDICTION theory, *RIBAVIRIN, *PLATELET count, *CLINICAL trials, *MEDICAL decision making, *PATIENTS, *THERAPEUTICS

المؤلفون: Macartney, Malcolm J.¹ malcolm.macartney@nhs.net, Irish, Dianne¹, Bridge, Simon H.¹, Garcia-Diaz, Ana¹, Booth, Clare L.¹, McCormick, Adele L.¹, Labbett, Wendy¹, Smith, Colette², Velazquez, Carmen³, Tanwar, Sudeep⁴, Trembling, Paul⁴, Jacobs, Michael³, Dusheiko, Geoff³, Rosenberg, William^3,4, Haque, Tanzina¹

المصدر: Antiviral Research. May2014, Vol. 105, p112-117. 6p.

مصطلحات موضوعية: *TELAPREVIR, *BOCEPREVIR, *VIRUS diseases, *HEPATITIS C treatment, *DRUG resistance, *VIRAL load, *THERAPEUTICS

المؤلفون: Ada Bertoli, Michael P. Manns, M. Katja Deterding, Vanni Borghi, Silvia Barbaliscia, Elisabetta Degasperi, Julian Schulze zur Wiesch, Velia Chiara Di Maio, Ansgar W. Lohse, Wolfgang Schmidt, Markus Cornberg, Christophe Moreno, Tomas Beyer, Federico García, Johannes Vermehren, Pietro Lampertico, Andreas E. Kremer, Laura Sighinolfi, Felix Piecha, Magdalena Lara, Pier Luigi Toniutto, Christoph Sarrazin, Antonio Craxì, Francesca Ceccherini-Silberstein, Jonas Schreiber, Jesús Santos, Ana Belén Pérez, Alessio Aghemo, William Gennari, Lorenzo Magenta, Manuel Alberto Macias Rodriguez, Heiner Wedermeyer, Ana Fuentes, Stephan Grunwald, Jose Miguel Rosales Zabal, Francisco Téllez, Dolores Merino, Burkhard Jäger, Miguel García Deltoro, Juan Manuel Pascasio-Acevedo, Blanca Figueruela, Andreas Stallmach, Renate Heyne, Valeria Ghisetti, Christoph P. Berg, Carlo Federico Perno, Elisa Fernández-Fuertes, Nikolaus Kordecki, Ana María Martinez Sapiña, Natalia Chueca, Andreas Herrmann, Eva Jägel-Guedes, Vincenza Calvaruso, Maurizio Zazzi, Massimo Andreoni, Lucio Boglione, Mario Angelico, Simona Francioso, Giuseppe Cariti, Cristina Quilez, Tiziano Allice, Christiana Graf, Leopoldo Muñoz-Medina, Fausto Baldanti, Rudolf E. Stauber, Jürgen Siebler, Julia Dietz, Maria Josefa Rodriguez Pardo, Kerstin Port, Heinz Zoller, Juan Carlos Alados, Stefan Zeuzem, Juan Ignacio Arenas Ruiz-Tapiador, Joaquín Cabezas, Stefania Paolucci, Axels Baumgarten, Kai-Henrik Peiffer, Adolfo de Salazar, Pietro Pozzoni, Miguel Jimenez, Hjördis Möller

المساهمون: Dietz J., Di Maio V.C., de Salazar A., Merino D., Vermehren J., Paolucci S., Kremer A.E., Lara M., Pardo M.R., Zoller H., Degasperi E., Peiffer K.-H., Sighinolfi L., Tellez F., Graf C., Ghisetti V., Schreiber J., Fernandez-Fuertes E., Boglione L., Munoz-Medina L., Stauber R., Gennari W., Figueruela B., Santos J., Lampertico P., Zeuzem S., Ceccherini-Silberstein F., Garcia F., Sarrazin C., Aghemo A., Allice T., Andreoni M., Angelico M., Baldanti F., Barbaliscia S., Bertoli A., Borghi V., Calvaruso V., Cariti G., Craxi A., Francioso S., Perno C.F., Pozzoni P., Toniutto P.L., Zazzi M., Perez A.B., Quilez C., Alados J.C., Cabezas J., Ruiz-Tapiador J.I.A., Jimenez M., Pascasio-Acevedo J.M., Rodriguez M.A.M., Zabal J.M.R., Deltoro M.G., Sapina A.M.M., Fuentes A., Chueca N., Berg C.P., Herrmann A., Stallmach A., Port K., Katja Deterding M., Wedermeyer H., Cornberg M., Manns M.P., Moreno C., Wiesch J.S.Z., Piecha F., Lohse A., Siebler J., Kordecki N., Magenta L., Jager B., Moller H., Heyne R., Beyer T., Grunwald S., Baumgarten A., Jagel-Guedes E., Schmidt W.

المصدر: Journal of Hepatology. 74:801-810

مصطلحات موضوعية: 0301 basic medicine, Hepatitis C Virus, medicine.medical_specialty, Sofosbuvir, Voxilaprevir, Population, resistance-associated substitutions, Direct-acting antiviral, Voxilaprevir/velpatasvir/sofosbuvir, Gastroenterology, Settore MED/07, Telaprevir, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Voxilaprevir/Velpatasvir/Sofosbuvir, Internal medicine, Boceprevir, Rescue therapy, medicine, Resistance-associated substitution, education, direct-acting antivirals, DAA, education.field_of_study, Hepatology, business.industry, virus diseases, Glecaprevir, HCV, rescue therapy, digestive system diseases, Pibrentasvir, Regimen, 030104 developmental biology, chemistry, 030211 gastroenterology & hepatology, Hepatitis C viru, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88cd0ab9dd512362a11eac31e987e6abTest
https://doi.org/10.1016/j.jhep.2020.11.017Test

المؤلفون: Bart Tarbet, Chunlong Ma, Brett L. Hurst, Jun Wang, Yanmei Hu, Tommy Szeto

المصدر: bioRxiv
article-version (status) pre
article-version (number) 1

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, viruses, Cathepsin L, Carbonates, Coronavirus OC43, Human, chemistry.chemical_compound, Coronavirus 229E, Human, Chlorocebus aethiops, boceprevir, Coronavirus 3C Proteases, chemistry.chemical_classification, Alanine, biology, Serine Endopeptidases, virus diseases, Drug Combinations, Infectious Diseases, Middle East Respiratory Syndrome Coronavirus, medicine.symptom, Oligopeptides, Proline, 030106 microbiology, Antiviral Agents, Article, Cell Line, 03 medical and health sciences, Leucine, Boceprevir, medicine, Animals, Humans, Vero Cells, Glycoproteins, Protease, SARS-CoV-2, HEK 293 cells, COVID-19, Virology, Adenosine Monophosphate, GC-376, respiratory tract diseases, COVID-19 Drug Treatment, Coronavirus NL63, Human, 030104 developmental biology, Enzyme, HEK293 Cells, chemistry, Mechanism of action, Cell culture, main protease, calpain inhibitor, Vero cell, biology.protein, Caco-2 Cells, Sulfonic Acids

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::849337b717619b237acbae1f9f408562Test
https://pubmed.ncbi.nlm.nih.gov/33140049Test

المؤلفون: Vanessa Duarte da Costa, Paulo Sergio Fonseca de Sousa, Carlos Eduardo Brandão-Mello, Lia Laura Lewis Ximenez de Souza Rodrigues, Elisabeth Lampe, Francisco C. A. Mello, Estevão Portela Nunes, Nathália Delvaux

المصدر: Clinics and Research in Hepatology and Gastroenterology. 43:700-706

مصطلحات موضوعية: Adult, Male, Simeprevir, Daclatasvir, Genotype, Sofosbuvir, Hepacivirus, Viral Nonstructural Proteins, Antiviral Agents, Telaprevir, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Boceprevir, Drug Resistance, Viral, medicine, Humans, Protease Inhibitors, NS3, Hepatology, business.industry, Gastroenterology, virus diseases, Hepatitis C, Hepatitis C, Chronic, medicine.disease, Virology, chemistry, 030220 oncology & carcinogenesis, Female, 030211 gastroenterology & hepatology, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6554bcf5174fea8849730829a36c694Test
https://doi.org/10.1016/j.clinre.2019.02.009Test

المؤلفون: Bart Tarbet, Chunlong Ma, Jun Wang, Yanmei Hu, Tommy Szeto, Brett L. Hurst

المصدر: ACS Infectious Diseases
bioRxiv

مصطلحات موضوعية: medicine.drug_class, medicine.medical_treatment, viruses, Pharmacology, Article, Cathepsin L, chemistry.chemical_compound, Boceprevir, medicine, boceprevir, chemistry.chemical_classification, Cathepsin, Protease, biology, Chemistry, SARS-CoV-2, virus diseases, COVID-19, GC-376, respiratory tract diseases, Enzyme, Mechanism of action, main protease, calpain inhibitor, Vero cell, biology.protein, Antiviral drug, medicine.symptom

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a86db48e7ca982fb552fabce2cd45d99Test
https://pubmed.ncbi.nlm.nih.gov/33645977Test

المؤلفون: Yuyong Zhou, Troels K. H. Scheel, Shan Feng, Jens Bukh, Karen A. Gammeltoft, Santseharay Ramirez, Judith M. Gottwein, Long V. Pham, Anna Offersgaard, Andrea Galli, Rui Costa, Carlos Rene Duarte Hernandez, Ulrik Fahnøe

المصدر: Antimicrobial Agents and Chemotherapy
Gammeltoft, K A, Zhou, Y, Duarte Hernandez, C R, Galli, A, Offersgaard, A, Costa, R, Pham, L V, Fahnøe, U, Feng, S, Scheel, T K H, Ramirez, S, Bukh, J & Gottwein, J M 2021, ' Hepatitis C Virus Protease Inhibitors Show Differential Efficacy and Interactions with Remdesivir for Treatment of SARS-CoV-2 in Vitro ', Antimicrobial Agents and Chemotherapy, vol. 65, no. 9, e02680-20 . https://doi.org/10.1128/AAC.02680-20Test

مصطلحات موضوعية: Viral Protease Inhibitors, Voxilaprevir, Vaniprevir, viruses, coronavirus, repurposing, synergy, Hepacivirus, Antiviral Agents, Telaprevir, chemistry.chemical_compound, Boceprevir, Chlorocebus aethiops, medicine, Animals, Humans, Pharmacology (medical), Protease Inhibitors, Vero Cells, Pharmacology, Alanine, SARS-CoV-2, Danoprevir, virus diseases, COVID-19, Glecaprevir, Hepatitis C, Chronic, Virology, Hepatitis C, antiviral, Adenosine Monophosphate, COVID-19 Drug Treatment, Infectious Diseases, Grazoprevir, chemistry, Narlaprevir, Spike Glycoprotein, Coronavirus, combination treatment, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0fc2c433c7de0ed40ca06a8bfe3c408Test
https://pubmed.ncbi.nlm.nih.gov/34097489Test

المؤلفون: Peihua Niu, Cheng Zhao, Yan Wu, George F. Gao, Wenjie Tan, Hao Song, Qisheng Wang, Fei Ye, Yong Feng, Huan Sun, Jianxun Qi, Baoying Huang, Yi Shi, Lifeng Fu, Feng Yu, Xuebing Li

المصدر: Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Pyrrolidines, medicine.medical_treatment, viruses, General Physics and Astronomy, 02 engineering and technology, Viral Nonstructural Proteins, medicine.disease_cause, Crystallography, X-Ray, Virus Replication, chemistry.chemical_compound, Catalytic Domain, Chlorocebus aethiops, lcsh:Science, Coronavirus 3C Proteases, Coronavirus, Multidisciplinary, Nanocrystallography, High-throughput screening, virus diseases, Proteases, 021001 nanoscience & nanotechnology, Cysteine Endopeptidases, 0210 nano-technology, Coronavirus Infections, Proline, Science, Pneumonia, Viral, RNA-dependent RNA polymerase, Biology, Antiviral Agents, General Biochemistry, Genetics and Molecular Biology, Virus, Article, 03 medical and health sciences, Betacoronavirus, Boceprevir, medicine, Animals, Protease Inhibitors, Pandemics, Vero Cells, Protease, Binding Sites, SARS-CoV-2, COVID-19, General Chemistry, biochemical phenomena, metabolism, and nutrition, RNA-Dependent RNA Polymerase, Virology, Feline infectious peritonitis, High-Throughput Screening Assays, COVID-19 Drug Treatment, Disease Models, Animal, 030104 developmental biology, chemistry, Vero cell, lcsh:Q, Sulfonic Acids

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1944eab284fa289b9ee413e830e95f5Test
http://europepmc.org/articles/PMC7474075Test

المؤلفون: R. Lavanya, Ravichandiran Velayutham, Himani Balutia, Kuldeep K. Roy, Rishitha Gundala

مصطلحات موضوعية: Simeprevir, NS3, Protease, business.industry, medicine.medical_treatment, virus diseases, medicine.disease, digestive system diseases, Telaprevir, chemistry.chemical_compound, Grazoprevir, chemistry, Paritaprevir, Boceprevir, medicine, Cancer research, Liver cancer, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::d94281cf56549e7b0ad36fe2fb27ab4cTest
https://doi.org/10.1016/b978-0-12-818168-3.00009-7Test

المؤلفون: E.C. Jones, S. Cure, Joris Diels, F. Bianic, S. Gavart

مصطلحات موضوعية: medicine.medical_specialty, Genotype, Proline, Hepacivirus, Pharmacology, Antiviral Agents, law.invention, Telaprevir, chemistry.chemical_compound, Randomized controlled trial, law, Internal medicine, Boceprevir, medicine, Credible interval, Humans, Randomized Controlled Trials as Topic, business.industry, Ribavirin, virus diseases, Bayes Theorem, General Medicine, Odds ratio, Hepatitis C, Chronic, chemistry, Meta-analysis, Drug Therapy, Combination, business, Oligopeptides, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c57cba2f311ba52487f9c8400d13e484Test