المؤلفون: Ivana Gotthardová, Ivan Tkáč

المصدر: Pharmacogenomics. 17:795-804

مصطلحات موضوعية: 0301 basic medicine, endocrine system, Pharmacogenomic Variants, endocrine system diseases, Incretin, 030209 endocrinology & metabolism, Type 2 diabetes, Biology, Pharmacology, Incretins, Polymorphism, Single Nucleotide, Glucagon-Like Peptide-1 Receptor, 03 medical and health sciences, 0302 clinical medicine, Genetics, medicine, Chymotrypsin, Humans, Hypoglycemic Agents, Allele, Dipeptidyl-Peptidase IV Inhibitors, Type 2 Diabetes Mellitus, medicine.disease, Pharmacogenomic Testing, Minor allele frequency, 030104 developmental biology, Diabetes Mellitus, Type 2, KCNQ1 Potassium Channel, Molecular Medicine, Transcription Factor 7-Like 2 Protein, TCF7L2, Pharmacogenetics

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18ed9a983504f61d4f1b6369f29f6c6fTest
https://doi.org/10.2217/pgs-2016-0011Test

المؤلفون: Cristina Barosa, Meera Shah, Robert A. Rizza, John G. Jones, Cátia Marques, Adrian Vella, Ron T. Varghese, Ivan Viegas

المصدر: Diabetes
ResearcherID

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Glucose uptake, 030209 endocrinology & metabolism, Type 2 diabetes, Biology, Polymorphism, Single Nucleotide, 03 medical and health sciences, 0302 clinical medicine, Insulin resistance, Internal medicine, Diabetes mellitus, Internal Medicine, medicine, Humans, Genetic Predisposition to Disease, Genetic Association Studies, Insulin, Middle Aged, Glucose clamp technique, medicine.disease, Metabolism, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 2, Liver, Gluconeogenesis, Case-Control Studies, Glucose Clamp Technique, Female, Insulin Resistance, Transcription Factor 7-Like 2 Protein, TCF7L2

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60d9731e5bd4ee00266d61765d9dacaaTest
https://doi.org/10.2337/db15-1593Test

المؤلفون: Angela Dardano, Giuseppe Daniele, Andrea Mari, Melania Gaggini, Cristina Bianchi, Giuseppina Basta, Mario Comassi, Amalia Gastaldelli, Stefano Del Prato, Roberto Miccoli

المصدر: The Journal of Clinical Endocrinology & Metabolism. 100:E1160-E1167

مصطلحات موضوعية: Blood Glucose, Male, Risk, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Clinical Biochemistry, Incretin, Type 2 diabetes, Biology, INSULIN-SECRETION, POLYPEPTIDE, Polymorphism, Single Nucleotide, Biochemistry, Glucagon, MECHANISMS, Cohort Studies, chemistry.chemical_compound, Endocrinology, BETA-CELL FUNCTION, Internal medicine, medicine, Humans, Genetic Predisposition to Disease, CARRIERS, POLYMORPHISMS, ASSOCIATION, PROINSULIN, INCRETIN, CATENIN, Glucose tolerance test, medicine.diagnostic_test, Insulin, Biochemistry (medical), Glucose Tolerance Test, Middle Aged, Postprandial Period, medicine.disease, Glucose, Postprandial, Diabetes Mellitus, Type 2, chemistry, Female, Glycated hemoglobin, Energy Metabolism, Transcription Factor 7-Like 2 Protein, TCF7L2

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1184815f32e8d6fb0311b878e0eee611Test
https://doi.org/10.1210/jc.2015-1172Test

المؤلفون: Jing Guo, Huili Wang, Ruirui Tian, Li Wei, Enting Ma

المصدر: Clinics, Vol 70, Iss 8, Pp 593-599 (2015)
Clinics
Clinics, Volume: 70, Issue: 8, Pages: 593-599, Published: AUG 2015
Clinics; v. 70 n. 8 (2015); 593-599
Clinics; Vol. 70 Núm. 8 (2015); 593-599
Clinics; Vol. 70 No. 8 (2015); 593-599
Universidade de São Paulo (USP)
instacron:USP

مصطلحات موضوعية: Male, Oncology, China, medicine.medical_specialty, Review, Type 2 diabetes, Polymorphism, Single Nucleotide, Body Mass Index, Risk Factors, Polymorphism (computer science), Internal medicine, Diabetes mellitus, Humans, Medicine, Genetic Association Studies, Genetics, lcsh:R5-920, business.industry, Type 2 Diabetes Mellitus, General Medicine, Odds ratio, medicine.disease, Confidence interval, Type 2 diabetes mellitus (T2DM), Meta-analysis, Diabetes Mellitus, Type 2, rs11196218A/G polymorphism, Female, Transcription factor 7-like 2 (TCF7L2), business, lcsh:Medicine (General), Publication Bias, Transcription Factor 7-Like 2 Protein, Body mass index

وصف الملف: text/html; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::745d3877aaa5827fa601ab1f33889bf7Test
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322015000800593&lng=en&tlng=enTest

المؤلفون: Martijn van de Bunt

المصدر: Diabetologia. 59:2292-2294

مصطلحات موضوعية: 0301 basic medicine, Genetics, Effector, Endocrinology, Diabetes and Metabolism, Locus (genetics), Genome-wide association study, Type 2 diabetes, Human physiology, Biology, ACSL5, medicine.disease, Polymorphism, Single Nucleotide, 03 medical and health sciences, 030104 developmental biology, Diabetes Mellitus, Type 2, Internal Medicine, medicine, Humans, Genetic Predisposition to Disease, TCF Transcription Factors, Transcription Factor 7-Like 2 Protein, TCF7L2, Gene

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdba14fa381eff45d3d32994fa96f0f0Test
https://doi.org/10.1007/s00125-016-4103-4Test

المؤلفون: Andreas Lechner, Rainer Lehmann, Norbert Stefan, Harald Grallert, Hans-Ulrich Häring, Robert Wagner, Louise Fritsche, Andreas Fritsche, Mirjam Sarief

المصدر: Diabetes Res. Clin. Pract. 146, 251-257 (2018)

مصطلحات موضوعية: 0301 basic medicine, endocrine system, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Physiology, 030209 endocrinology & metabolism, Type 2 diabetes, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Pregnancy, Risk Factors, Diabetes mellitus, Genotype, Genetic variation, Liver fat, Internal Medicine, medicine, Humans, Gestational Diabetes, Type 2 Diabetes, Oral Glucose Tolerance Test, Tcf7l2, Insulin Sensitivity, Liver Fat, Proinsulin, business.industry, nutritional and metabolic diseases, Genetic Variation, General Medicine, Middle Aged, medicine.disease, Gestational diabetes, Diabetes, Gestational, 030104 developmental biology, Diabetes Mellitus, Type 2, Female, business, TCF7L2, Transcription Factor 7-Like 2 Protein

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79e06625ca4963b2775aaee78c340b44Test
https://pubmed.ncbi.nlm.nih.gov/30419301Test

المؤلفون: Kofi Agyenim-Boateng, Ayo P. Doumatey, Adebowale Adeyemo, Charles N. Rotimi, Settara C. Chandrasekharappa, Albert G.B. Amoah, Norann A. Zaghloul, Thomas Johnson, William Balogun, Daniel Shriner, Joseph Acheampong, Guanjie Chen, Jie Zhou, Olufemi Fasanmade, Clement Adebamowo, Benjamin A. Eghan, South Africa Zulu Type Diabetes Case-Control Study, Jokotade Adeleye, Jessica E. Nesmith, Francis S. Collins, Samuel Owusu, Timothy L. Hostelley, Carmen C. Leitch, Johnnie Oli, Godfrey Okafor, Georgia M. Dunston, Amy R. Bentley

المساهمون: Adeyemo, Adebowale A [0000-0002-3105-3231], Chen, Guanjie [0000-0002-5745-5618], Bentley, Amy R [0000-0002-0827-9101], Rotimi, Charles N [0000-0001-5759-053X], Apollo - University of Cambridge Repository

المصدر: Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)

مصطلحات موضوعية: 0301 basic medicine, Blood Glucose, Male, CRISPR-Cas9 genome editing, endocrine system diseases, medicine.medical_treatment, General Physics and Astronomy, Apoptosis, 02 engineering and technology, Type 2 diabetes, Ghana, Genome-wide association studies, Gene Knockout Techniques, Mice, Africa, Northern, Insulin-Secreting Cells, Insulin, RNA, Small Interfering, lcsh:Science, Zebrafish, Genetics, Gene Editing, Developing world, education.field_of_study, Multidisciplinary, Homozygote, Middle Aged, 021001 nanoscience & nanotechnology, 3. Good health, Female, Beta cell, 0210 nano-technology, Transcription Factor 7-Like 2 Protein, Genotype, Science, Population, Nigeria, Single-nucleotide polymorphism, Locus (genetics), Biology, Polymorphism, Single Nucleotide, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Diabetes mellitus, medicine, SNP, Animals, Humans, Genetic Predisposition to Disease, education, Genetic Association Studies, Base Sequence, DNA Helicases, nutritional and metabolic diseases, General Chemistry, medicine.disease, Kenya, Disease Models, Animal, 030104 developmental biology, Glucose, Diabetes Mellitus, Type 2, Mutation, lcsh:Q, CRISPR-Cas Systems, Transcriptome

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a6cbf062e794e3bf54c14c4f9cbb616Test
https://pubmed.ncbi.nlm.nih.gov/31324766Test

المؤلفون: M Iwasaki, S Tsugane, Mitsuhiko Noda, Kazuki Yasuda, Atsushi Goto, T Mizoue, M Inoue, Norie Sawada, Taiki Yamaji, M Goto

المصدر: Diabetic medicine : a journal of the British Diabetic Association. 35(5)

مصطلحات موضوعية: 0301 basic medicine, Male, Endocrinology, Diabetes and Metabolism, Type 2 diabetes, Endocrinology, Japan, Risk Factors, Medicine, Prospective Studies, tRNA Methyltransferases, Incidence, Nuclear Proteins, Middle Aged, KCNQ1 Potassium Channel, Female, Risk assessment, Transcription Factor 7-Like 2 Protein, Adult, medicine.medical_specialty, Alpha-Ketoglutarate-Dependent Dioxygenase FTO, Single-nucleotide polymorphism, Risk Assessment, 03 medical and health sciences, Asian People, Internal medicine, Internal Medicine, Cyclin-Dependent Kinase Inhibitor p18, Humans, Genetic Predisposition to Disease, Risk factor, Potassium Channels, Inwardly Rectifying, CDKAL1, Cyclin-Dependent Kinase Inhibitor p16, Aged, Cyclin-Dependent Kinase Inhibitor p15, Homeodomain Proteins, business.industry, Case-control study, Odds ratio, medicine.disease, PPAR gamma, Insulin-Like Growth Factor Binding Protein 2, 030104 developmental biology, Diabetes Mellitus, Type 2, Case-Control Studies, Nested case-control study, Ubiquitin-Conjugating Enzymes, Insulin Receptor Substrate Proteins, business, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c321676fe6811f121c6de34046b142f1Test
https://pubmed.ncbi.nlm.nih.gov/29444352Test

المؤلفون: Adrian Vella, Aleksey V. Matveyenko

المصدر: Journal of Biological Chemistry. 293:14190-14191

مصطلحات موضوعية: 0301 basic medicine, Diabetes risk, 030209 endocrinology & metabolism, Type 2 diabetes, Biology, Fine line, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Insulin-Secreting Cells, Insulin Secretion, medicine, Animals, Humans, Secretion, Insulin secretion, Molecular Biology, Cell Proliferation, Mechanism (biology), Cell Biology, medicine.disease, Phenotype, Cell biology, 030104 developmental biology, Diabetes Mellitus, Type 2, Editors' Picks Highlights, Transcription Factor 7-Like 2 Protein, TCF7L2

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf165dc8c7cb6402ed1d2fbb667f7e5cTest
https://doi.org/10.1074/jbc.h118.005121Test

المؤلفون: Linlin Li, Jingzhi Zhao, Ming Zhang, Jianfeng Zhang, Kaiping Gao, Xinping Luo, Jinjin Wang, Chongjian Wang, Dongsheng Hu

المصدر: Nutrients
Volume 7
Issue 6
Pages 4763-4777
Nutrients, Vol 7, Iss 6, Pp 4763-4777 (2015)

مصطلحات موضوعية: Adult, Male, China, Linkage disequilibrium, Genotyping Techniques, endocrine system diseases, lcsh:TX341-641, Single-nucleotide polymorphism, Biology, Bioinformatics, Polymorphism, Single Nucleotide, Article, Linkage Disequilibrium, Body Mass Index, Young Adult, Asian People, Humans, Genetic Predisposition to Disease, WNT signaling pathway, Allele, Alleles, beta Catenin, Aged, Aged, 80 and over, Genetics, Chinese, Nutrition and Dietetics, Multifactor dimensionality reduction, Haplotype, Wnt signaling pathway, nutritional and metabolic diseases, LRP5, Middle Aged, Glucagon, Logistic Models, Low Density Lipoprotein Receptor-Related Protein-5, Diabetes Mellitus, Type 2, Haplotypes, Case-Control Studies, Female, type 2 diabetes, polymorphisms, Transcription Factor 7-Like 2 Protein, lcsh:Nutrition. Foods and food supply, TCF7L2, Food Science

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4f9c78e0fe4b829061168f823416488Test
https://doi.org/10.3390/nu7064763Test