دورية أكاديمية
Spinal meningiomas: Influence of cord compression and radiological features on preoperative functional status and outcome
| العنوان: | Spinal meningiomas: Influence of cord compression and radiological features on preoperative functional status and outcome |
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| المؤلفون: | Baro V., Moiraghi A., Carlucci V., Paun L., Anglani M., Ermani M., Saladino A., Chioffi F., D'Avella D., Landi A., Bartoli A., Dimeco F., Schaller K., Denaro L., Tessitore E. |
| المساهمون: | V. Baro, A. Moiraghi, V. Carlucci, L. Paun, M. Anglani, M. Ermani, A. Saladino, F. Chioffi, D. D'Avella, A. Landi, A. Bartoli, F. Dimeco, K. Schaller, L. Denaro, E. Tessitore |
| بيانات النشر: | MDPI AG |
| سنة النشر: | 2021 |
| المجموعة: | The University of Milan: Archivio Istituzionale della Ricerca (AIR) |
| مصطلحات موضوعية: | Cord compression, Functional outcome, Magnetic resonance imaging, McCormick scale, Spinal meningioma, Tumor volume, Settore MED/27 - Neurochirurgia |
| الوصف: | Background: Radiological parameters predicting the postoperative neurological outcome after resection of a spinal meningioma (SM) are poorly studied, with controversial results. Methods: Observational multicenter cohort (2011–2018) of adult patients undergoing surgery for resection of SM. Tumor-canal volume ratio (TCR), the areas related to the cord and tumor occupancy at maximum compression, the presence of dural tail, calcifications, signs of myelopathy, and postoperative cord expansion were compared with the modified McCormick scale (mMCS) preoperative and at follow-up. Results: In the cohort (n = 90 patients), cord and tumor occupancy as well as cord compression and tumor volume showed a correlation with preoperative mMCS (p < 0.05, R −0.23; p < 0.001, R 0.35; p < 0.005, R −0.29; p < 0.001, R 0.42). Cord occupancy had a strong correlation with cord compression (p < 0.001, R 0.72). Tumor occupancy and TCR were correlated with relative outcome at follow-up (p < 0.005 R 0.3; p < 0.005 R 0.29). No correlation was found between cord re-expansion and clinical outcome at follow-up. Finally, a correlation was shown between preoperative signs of cord myelopathy and mMCS (p < 0.05 R 0.21) at follow-up. Conclusions: Larger tumors showed lower preoperative functional status and a worse clinical outcome. Moreover, preoperative T2 cord signal changes are correlated with a poorer outcome. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/34439337; info:eu-repo/semantics/altIdentifier/wos/WOS:000688841600001; volume:13; issue:16; firstpage:1; lastpage:13; numberofpages:13; journal:CANCERS; http://hdl.handle.net/2434/902957Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85113132917 |
| DOI: | 10.3390/cancers13164183 |
| الإتاحة: | https://doi.org/10.3390/cancers13164183Test http://hdl.handle.net/2434/902957Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.74766656 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/cancers13164183 |
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