المؤلفون: Prota, Andrea E.¹ andrea.prota@psi.ch, Lucena-Agell, Daniel², Yuntao Ma³, Estevez-Gallego, Juan², Shuo Li³, Bargsten, Katja¹, Josa-Prado, Fernando², Altmann, Karl-Heinz⁴, Gaillard, Natacha¹, Shinji Kamimura⁵, Mühlethaler, Tobias¹, Gago, Federico⁶, Oliva, Maria A.², Steinmetz, Michel O.^1,7, Wei-Shuo Fang³ wfang@imm.ac.cn, Díaz, J. Fernando² fer@cib.csic.es

المصدر: eLife. 3/28/2023, p1-35. 35p.

مصطلحات موضوعية: *TUBULINS, *MICROTUBULES, *TAXANES, *MOLECULAR dynamics, *PACLITAXEL, *ATOMIC interactions, *CRYSTAL structure

المؤلفون: Pérez-Peña, Helena, Abel, Anne-Catherine, Shevelev, Maxim, Prota, Andrea E., Pieraccini, Stefano, Horvath, Dragos

المصدر: Biomolecules (2218-273X); Feb2023, Vol. 13 Issue 2, p285, 35p

مصطلحات موضوعية: TUBULINS, DRUG design, COMPUTER-assisted drug design, DESIGN techniques, COMPUTER-aided design, MOLECULAR dynamics

المؤلفون: Boiarska, Zlata, Pérez‐Peña, Helena, Abel, Anne‐Catherine, Marzullo, Paola, Álvarez‐Bernad, Beatriz, Bonato, Francesca, Santini, Benedetta, Horvath, Dragos, Lucena‐Agell, Daniel, Vasile, Francesca, Sironi, Maurizio, Díaz, J. Fernando, Prota, Andrea E., Pieraccini, Stefano, Passarella, Daniele

المصدر: Chemistry - A European Journal; 1/24/2023, Vol. 29 Issue 5, p1-12, 12p

مصطلحات موضوعية: MICROTUBULES, TUBULINS, CYTOTOXINS, NATURAL products

المؤلفون: Mühlethaler, Tobias, Milanos, Lampros, Ortega, Jose Antonio, Blum, Thorsten B., Gioia, Dario, Roy, Bibhas, Prota, Andrea E., Cavalli, Andrea, Steinmetz, Michel O.

المصدر: Angewandte Chemie; 6/20/2022, Vol. 134 Issue 25, p1-11, 11p

مصطلحات موضوعية: TUBULINS, SMALL molecules, DRUG design, CHEMICAL synthesis, MICROTUBULES

المؤلفون: Marzullo, Paola, Boiarska, Zlata, Pérez‐Peña, Helena, Abel, Anne‐Catherine, Álvarez‐Bernad, Beatriz, Lucena‐Agell, Daniel, Vasile, Francesca, Sironi, Maurizio, Altmann, Karl‐Heinz, Prota, Andrea E., Díaz, J. Fernando, Pieraccini, Stefano, Passarella, Daniele

المصدر: Chemistry - A European Journal; 1/10/2022, Vol. 28 Issue 2, p1-10, 10p

مصطلحات موضوعية: TUBULINS, MOLECULAR docking, CRYSTAL structure, CANCER treatment, ACYLATION

المؤلفون: Mühlethaler, Tobias, Gioia, Dario, Prota, Andrea E., Sharpe, May E., Cavalli, Andrea, Steinmetz, Michel O.

المصدر: Angewandte Chemie; 6/7/2021, Vol. 133 Issue 24, p13443-13454, 12p

مصطلحات موضوعية: BINDING site assay, TUBULINS, SMALL molecules, ALLOSTERIC regulation, MOLECULAR dynamics, BINDING sites

المؤلفون: Matthew, Susan, Qi-Yin Chen, Ratnayake, Ranjala, Fermaintt, Charles S., Lucena-Agell, Daniel, Bonato, Francesca, Prota, Andrea E., Seok Ting Lim, Xiaomeng Wang, Díaz, J. Fernando, Risinger, April L., Paul, Valerie J., Oliva, Maria Ángela, Luesch, Hendrik

المصدر: Proceedings of the National Academy of Sciences of the United States of America; 3/2/2021, Vol. 118 Issue 9, p1-11, 11p

مصطلحات موضوعية: TUBULINS, MARINE natural products, BINDING agents, NATURAL products, BINDING sites

المؤلفون: Steinmetz, Michel O.^1,2 michel.steinmetz@psi.ch, Prota, Andrea E.¹ andrea.prota@psi.ch

المصدر: Trends in Cell Biology. Oct2018, Vol. 28 Issue 10, p776-792. 17p.

مصطلحات موضوعية: *MICROTUBULES, *PACLITAXEL, *EUKARYOTIC cells, *ANTINEOPLASTIC agents, *TUBULINS, *CANCER treatment, THERAPEUTIC use of alkaloids

المؤلفون: Boiarska, Zlata, Pérez‐Peña, Helena, Abel, Anne‐Catherine, Marzullo, Paola, Álvarez‐Bernad, Beatriz, Bonato, Francesca, Santini, Benedetta, Horvath, Dragos, Lucena‐Agell, Daniel, Vasile, Francesca, Sironi, Maurizio, Díaz, J. Fernando, Prota, Andrea E., Pieraccini, Stefano, Passarella, Daniele

المصدر: Chemistry - A European Journal; 1/24/2023, Vol. 29 Issue 5, p1-1, 1p

مصطلحات موضوعية: TUBULINS, TREE trunks

المؤلفون: Waight, Andrew B., Bargsten, Katja, Doronina, Svetlana, Steinmetz, Michel O., Sussman, Django, Prota, Andrea E.

المصدر: PLoS ONE; 8/12/2016, Vol. 11 Issue 8, p1-14, 14p

مصطلحات موضوعية: CANCER cells, ANTINEOPLASTIC agents, TUBULINS, MICROTUBULES, DRUG synergism