نتائج البحث - "Simone M. Goldinger"

1

Clinical outcome of concomitant vs interrupted BRAF inhibitor therapy during radiotherapy in melanoma patients

المصدر: British Journal of Cancer

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Cancer Research, Radiation-Sensitizing Agents, Skin Neoplasms, medicine.medical_treatment, Medizin, Cohort Studies, 0302 clinical medicine, Antineoplastic Combined Chemotherapy Protocols, Oximes, Vemurafenib, Prospective cohort study, Melanoma, Aged, 80 and over, Imidazoles, Middle Aged, Treatment Outcome, 030220 oncology & carcinogenesis, Female, medicine.drug, Adult, Proto-Oncogene Proteins B-raf, medicine.medical_specialty, Adolescent, Drug Administration Schedule, BRAF, 03 medical and health sciences, Young Adult, Internal medicine, medicine, Humans, ddc:610, dabrafenib, Protein Kinase Inhibitors, radiotherapy, Aged, Retrospective Studies, business.industry, Dabrafenib, Retrospective cohort study, medicine.disease, Radiation therapy, radiation, 030104 developmental biology, Concomitant, Clinical Study, Skin cancer, business

وصف الملف: application/octet-stream

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1e8f1dc9f3855c01558c2eeec19ddedTest
http://europepmc.org/articles/PMC5886123Test

2

A first‐in‐human phase I, multicenter, open‐label, dose‐escalation study of the oral RAF/VEGFR‐2 inhibitor (RAF265) in locally advanced or metastatic melanoma independent from BRAF mutation status

المؤلفون: Kevin B. Kim, Oliver Krieter, David F. McDermott, Keith T. Flaherty, Lyhping Lam, Shefali Kakar, Benjamin Izar, F. Stephen Hodi, Michael B. Atkins, Donald P. Lawrence, Simone M. Goldinger, William H. Sharfman, Reinhard Dummer, Ravi K. Amaravadi, Z. Tang, Jeffrey A. Sosman, Igor Puzanov

المصدر: Cancer Medicine

مصطلحات موضوعية: Placental growth factor, Oncology, Male, Cancer Research, Pathology, Angiogenesis, Pyridines, medicine.medical_treatment, 0302 clinical medicine, 030212 general & internal medicine, Molecular Targeted Therapy, Neoplasm Metastasis, BRAF wild‐type, Biomarker analysis, Melanoma, Original Research, Aged, 80 and over, Imidazoles, Middle Aged, Treatment Outcome, 030220 oncology & carcinogenesis, BRAF‐mutant, Immunohistochemistry, Female, Drug Monitoring, metastatic melanoma, Adult, Proto-Oncogene Proteins B-raf, medicine.medical_specialty, Maximum Tolerated Dose, Antineoplastic Agents, 03 medical and health sciences, Pharmacokinetics, Internal medicine, medicine, Humans, Radiology, Nuclear Medicine and imaging, RAF265, Adverse effect, Protein Kinase Inhibitors, Aged, Neoplasm Staging, business.industry, Growth factor, Clinical Cancer Research, medicine.disease, Pharmacodynamics, Mutation, business, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d11750763d2c877bc35ec8877ec9195bTest
http://europepmc.org/articles/PMC5548886Test

3

Liver Metastasis and Treatment Outcome with Anti-PD-1 Monoclonal Antibody in Patients with Melanoma and NSCLC

المصدر: Cancer immunology research, vol 5, iss 5

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Cancer Research, Pathology, Lung Neoplasms, Programmed Cell Death 1 Receptor, Kaplan-Meier Estimate, Pembrolizumab, CD8-Positive T-Lymphocytes, Metastasis, Antineoplastic Agents, Immunological, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Monoclonal, 80 and over, Medicine, Lymphocytes, Non-Small-Cell Lung, Melanoma, Humanized, Lung, Cancer, Aged, 80 and over, biology, Liver Disease, Liver Neoplasms, Lung Cancer, Pharmacology and Pharmaceutical Sciences, Middle Aged, Treatment Outcome, Immunological, 030220 oncology & carcinogenesis, Cohort, Female, Antibody, Adult, medicine.medical_specialty, Oncology and Carcinogenesis, Immunology, Antineoplastic Agents, Antibodies, Monoclonal, Humanized, Article, Disease-Free Survival, Antibodies, Young Adult, 03 medical and health sciences, Lymphocytes, Tumor-Infiltrating, Clinical Research, Internal medicine, Carcinoma, Humans, Tumor-Infiltrating, Lung cancer, Aged, business.industry, medicine.disease, 030104 developmental biology, biology.protein, Digestive Diseases, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e6e83e1062cd8697d5a6ca0e4709a53Test
https://doi.org/10.1158/2326-6066.cir-16-0325Test

4

Anti-PD-1/PD-L1 immunotherapy in patients with solid organ transplant, HIV or hepatitis B/C infection

المصدر: Eur J Cancer

مصطلحات موضوعية: 0301 basic medicine, Graft Rejection, Male, Cancer Research, medicine.medical_specialty, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Medizin, HIV Infections, Pembrolizumab, Gastroenterology, Organ transplantation, Article, B7-H1 Antigen, 03 medical and health sciences, 0302 clinical medicine, Antineoplastic Agents, Immunological, Hepatitis B, Chronic, Postoperative Complications, Internal medicine, Neoplasms, medicine, Humans, Molecular Targeted Therapy, Melanoma, Aged, Retrospective Studies, Hepatitis, business.industry, Cancer, Immunotherapy, Hepatitis C, Hepatitis B, Hepatitis C, Chronic, Middle Aged, medicine.disease, Transplant Recipients, Neoplasm Proteins, 030104 developmental biology, Treatment Outcome, Oncology, 030220 oncology & carcinogenesis, Female, business, Viral load

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88ca2382f6383ee824a1796afdc859feTest
https://europepmc.org/articles/PMC10176037Test/

5

Efficacy and safety of oral alitretinoin in severe oral lichen planus - results of a prospective pilot study

المؤلفون: Antonio Cozzio, Mirjana Urosevic-Maiwald, Anna L. Frauchiger, Simone M. Goldinger, Lars E. French, Daniella Jenni, Jivko Kamarachev, Michael Kunz, M. Dippel, Benedetta Belloni, Emmanuella Guenova, J. Mangana, Jil Dreier, Reinhard Dummer

المساهمون: University of Zurich, Dummer, R

المصدر: Journal of the European Academy of Dermatology and Venereology. 30:293-298

مصطلحات موضوعية: Male, medicine.medical_specialty, Time Factors, Administration, Oral, Antineoplastic Agents, Pilot Projects, Tretinoin, 610 Medicine & health, Dermatology, Severity of Illness Index, 2708 Dermatology, 030207 dermatology & venereal diseases, 03 medical and health sciences, Alitretinoin, 0302 clinical medicine, Recurrence, Severity of illness, medicine, Clinical endpoint, Humans, Prospective Studies, Adverse effect, Prospective cohort study, Dose-Response Relationship, Drug, business.industry, Standard treatment, Mouth Mucosa, 10177 Dermatology Clinic, 2725 Infectious Diseases, 030206 dentistry, Middle Aged, medicine.disease, Surgery, Clinical trial, stomatognathic diseases, Retinoid X Receptors, Treatment Outcome, Infectious Diseases, Female, Oral lichen planus, business, Follow-Up Studies, Lichen Planus, Oral, medicine.drug

وصف الملف: 620_Kunz M. et al._Efficacy and safety of oral alitretinoin in severe oral lichen planus_JEADV 2015.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74da6304e63543d9f0741491ec737f2aTest
https://doi.org/10.1111/jdv.13444Test

6

Ipilimumab alone or in combination with nivolumab after progression on anti-PD-1 therapy in advanced melanoma

المساهمون: University of Zurich, Zimmer, Lisa

المصدر: European journal of cancer (Oxford, England : 1990). 75

مصطلحات موضوعية: 0301 basic medicine, Oncology, Adult, Male, Cancer Research, medicine.medical_specialty, Skin Neoplasms, Programmed Cell Death 1 Receptor, Medizin, 610 Medicine & health, Ipilimumab, Pembrolizumab, Kaplan-Meier Estimate, Antibodies, Monoclonal, Humanized, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Medicine, Humans, 1306 Cancer Research, Melanoma, Advanced melanoma, Aged, Retrospective Studies, Aged, 80 and over, business.industry, Anti pd 1, 10177 Dermatology Clinic, Antibodies, Monoclonal, Retrospective cohort study, Middle Aged, medicine.disease, Surgery, 030104 developmental biology, Nivolumab, Treatment Outcome, 030220 oncology & carcinogenesis, Disease Progression, 2730 Oncology, Female, business, Progressive disease, medicine.drug

وصف الملف: Publikation_Goldinger.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b2bf6eab2d21cf7deeefc52fb9bc7b3Test
https://pubmed.ncbi.nlm.nih.gov/28214657Test

7

Pembrolizumab-triggered Uveitis: An Additional Surrogate Marker for Responders in Melanoma Immunotherapy?

المؤلفون: Samia Abed Maillard, Lukas Flatz, Daniel E. Speiser, Reinhard Rüesch, Fabienne Keller, Stefan Diem, Simone M. Goldinger, Ursula Urner-Bloch, Reinhard Dummer, Marco Siano

المساهمون: University of Zurich, Flatz, Lukas

المصدر: Journal of Immunotherapy

مصطلحات موضوعية: Oncology, Male, Cancer Research, medicine.medical_specialty, Skin Neoplasms, medicine.medical_treatment, Immunology, Programmed Cell Death 1 Receptor, 610 Medicine & health, Ipilimumab, Autoimmunity, Pembrolizumab, Antibodies, Monoclonal, Humanized, Uveitis, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Immunology and Allergy, Humans, 1306 Cancer Research, CTLA-4 Antigen, Colitis, Melanoma, Aged, Pharmacology, 2403 Immunology, Surrogate endpoint, business.industry, 10177 Dermatology Clinic, Immunotherapy, Middle Aged, medicine.disease, 3. Good health, 3004 Pharmacology, Treatment Outcome, 030220 oncology & carcinogenesis, Monoclonal, 2723 Immunology and Allergy, 030221 ophthalmology & optometry, Neoplasms, Unknown Primary, business, medicine.drug

وصف الملف: 667_Diem S. et al._Pembrolizumab-trigged Uveitis_Immunotherapy 2016.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1463f1e7d3676f85f258311a918183d6Test
https://pubmed.ncbi.nlm.nih.gov/27662340Test

8

An exploratory study investigating the metabolic activity and local cytokine profile in patients with melanoma treated with pazopanib and paclitaxel

المؤلفون: Michael Kunz, Phil F. Cheng, Emmanuella Guenova, S. Thurneysen, Reinhard Dummer, Simone M. Goldinger, Mirjam Nägeli, M. Ziegler, J. Mangana, Nicoletta F Jaberg-Bentele, Hannes W. Nagel, Mitch Levesque

المصدر: The British journal of dermatology. 175(5)

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, medicine.medical_specialty, Indazoles, Skin Neoplasms, Paclitaxel, medicine.drug_class, medicine.medical_treatment, Administration, Oral, Dermatology, Pharmacology, Tyrosine-kinase inhibitor, Drug Administration Schedule, Pazopanib, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, CXCL13, Infusions, Intravenous, Melanoma, Sulfonamides, medicine.diagnostic_test, business.industry, medicine.disease, 3. Good health, Up-Regulation, CXCL1, 030104 developmental biology, Cytokine, Pyrimidines, Treatment Outcome, chemistry, 030220 oncology & carcinogenesis, Skin biopsy, Cytokines, Female, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87069b105088f39a96cedaa42343db17Test
https://pubmed.ncbi.nlm.nih.gov/27168024Test

9

Acquired BRAF inhibitor resistance: A multicenter meta-analysis of the spectrum and frequencies, clinical behaviour, and phenotypic associations of resistance mechanisms

المصدر: European journal of cancer (Oxford, England : 1990), vol 51, iss 18

مصطلحات موضوعية: Oncology, Neuroblastoma RAS viral oncogene homolog, Male, Cancer Research, Skin Neoplasms, Time Factors, Resistance, DNA Mutational Analysis, Drug Resistance, Medizin, Kaplan-Meier Estimate, Bioinformatics, medicine.disease_cause, Risk Factors, 2.1 Biological and endogenous factors, Aetiology, Vemurafenib, Melanoma, Cancer, Mutation, Tumor, Dabrafenib, Acquired, Middle Aged, Phenotype, Europe, Treatment Outcome, Splice, Meta-analysis, Public Health and Health Services, Disease Progression, Female, medicine.drug, Signal Transduction, Proto-Oncogene Proteins B-raf, medicine.medical_specialty, Oncology and Carcinogenesis, NRAS, Antineoplastic Agents, Biology, Disease-Free Survival, Article, BRAF, MEK1, Clinical Research, Internal medicine, Genetics, medicine, Biomarkers, Tumor, Humans, Genetic Predisposition to Disease, Oncology & Carcinogenesis, Protein Kinase Inhibitors, Proportional Hazards Models, Proportional hazards model, Australia, medicine.disease, MAPK, United States, Drug Resistance, Neoplasm, Neoplasm, Biomarkers

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d736e92c73836efddc7f57510f57badTest
https://pubmed.ncbi.nlm.nih.gov/26608120Test

10

Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial

المساهمون: University of Zurich, Ribas, Antoni

المصدر: The Lancet. Oncology, vol 16, iss 8
Lancet Oncol

مصطلحات موضوعية: Oncology, Male, Skin Neoplasms, Time Factors, Medizin, Drug Resistance, Pembrolizumab, Kaplan-Meier Estimate, chemistry.chemical_compound, Antineoplastic Combined Chemotherapy Protocols, Monoclonal, 80 and over, Melanoma, Humanized, Cancer, Aged, 80 and over, education.field_of_study, Antibodies, Monoclonal, 10177 Dermatology Clinic, Middle Aged, Intention to Treat Analysis, Treatment Outcome, 6.1 Pharmaceuticals, Disease Progression, Female, 2730 Oncology, medicine.drug, Adult, medicine.medical_specialty, Adolescent, Dacarbazine, Population, Clinical Trials and Supportive Activities, Oncology and Carcinogenesis, Ipilimumab, Antineoplastic Agents, 610 Medicine & health, Antibodies, Monoclonal, Humanized, Article, Antibodies, Disease-Free Survival, Young Adult, Clinical Research, Internal medicine, medicine, Humans, Oncology & Carcinogenesis, education, Aged, Performance status, business.industry, Evaluation of treatments and therapeutic interventions, Interim analysis, medicine.disease, Carboplatin, Surgery, chemistry, Drug Resistance, Neoplasm, Neoplasm, business, Progressive disease

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4cfc7c0dc19ed0d5bc8a82c2ccdcc1eTest
https://doi.org/10.5167/uzh-113041Test

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