دورية أكاديمية
Pharmacokinetic drivers of toxicity for basic molecules: Strategy to lower pKa results in decreased tissue exposure and toxicity for a small molecule Met inhibitor
| العنوان: | Pharmacokinetic drivers of toxicity for basic molecules: Strategy to lower pKa results in decreased tissue exposure and toxicity for a small molecule Met inhibitor |
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| المؤلفون: | Diaz, Dolores, Ford, Kevin A., Hartley, Dylan P., Harstad, Eric B., Cain, Gary R., Achilles-Poon, Kirsten, Nguyen, Trung, Peng, Jing, Zheng, Zhong, Merchant, Mark, Sutherlin, Daniel P., Gaudino, John J., Kaus, Robert, Lewin-Koh, Sock C., Choo, Edna F., Liederer, Bianca M., Dambach, Donna M. |
| المصدر: | Toxicology and Applied Pharmacology ; volume 266, issue 1, page 86-94 ; ISSN 0041-008X |
| بيانات النشر: | Elsevier BV |
| سنة النشر: | 2013 |
| المجموعة: | ScienceDirect (Elsevier - Open Access Articles via Crossref) |
| مصطلحات موضوعية: | Pharmacology, Toxicology |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1016/j.taap.2012.10.026 |
| الإتاحة: | https://doi.org/10.1016/j.taap.2012.10.026Test https://api.elsevier.com/content/article/PII:S0041008X12004681?httpAccept=text/xmlTest https://api.elsevier.com/content/article/PII:S0041008X12004681?httpAccept=text/plainTest |
| حقوق: | https://www.elsevier.com/tdm/userlicense/1.0Test/ |
| رقم الانضمام: | edsbas.E42D9C94 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.taap.2012.10.026 |
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