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المؤلفون: Jason A. Carter, Léonie Strömich, Matthew Peacey, Sarah R. Chapin, Lars Velten, Lars M. Steinmetz, Benedikt Brors, Sheena Pinto, Hannah V. Meyer
المصدر: Nature Communications. 13
مصطلحات موضوعية: Multidisciplinary, Central tolerance, General Physics and Astronomy, Cell Differentiation, Epithelial Cells, Thymus Gland, General Chemistry, General Biochemistry, Genetics and Molecular Biology, Epitopes, Humans, Data integration, Gene expression, Transcriptome, Transcriptomics
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a43e221d3ce4d90f0900d8b921378109Test
https://doi.org/10.1038/s41467-022-31750-1Test -
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المؤلفون: Sheena Pinto, Bruno Kyewski, Benedikt Brors, Corey N. Miller, Chloé Michel, Rita Küchler, Mark S. Anderson
المصدر: The Journal of Immunology. 199:3488-3503
مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, Cellular differentiation, Immunology, Cell, Apoptosis, Thymus Gland, Rats, Sprague-Dawley, Mice, 03 medical and health sciences, Agglutinin, Pregnancy, Lectins, medicine, Animals, Humans, Immunology and Allergy, Cell Lineage, Cells, Cultured, Mice, Knockout, Regulation of gene expression, MHC class II, biology, Histocompatibility Antigens Class II, FOXN1, Cell Differentiation, Epithelial Cells, Rats, Cell biology, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, Gene Expression Regulation, biology.protein, Female, Biomarkers, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70fefd1ab5ec945e00696024102c279fTest
https://doi.org/10.4049/jimmunol.1700203Test -
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المؤلفون: Bruno Kyewski, Sheena Pinto, Wolfgang Huber, Michelle Nguyen, Lars M. Steinmetz, Rita Küchler, Alejandro Reyes, Kristin Rattay, Philip Brennecke
المصدر: Nature immunology
مصطلحات موضوعية: Immunology, Autoimmunity, Thymus Gland, Biology, Autoantigens, Article, Mice, Single-cell analysis, Gene expression, Immunology and Allergy, Animals, Humans, RNA, Messenger, Gene, Regulation of gene expression, Genetics, Gene Expression Profiling, RNA, Epithelial Cells, Chromatin Assembly and Disassembly, Chromatin, Cell biology, Gene expression profiling, Self Tolerance, Gene Expression Regulation, Ectopic expression, Single-Cell Analysis
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::831e3424f869d132aa0b4c8e6fb34f21Test
http://europepmc.org/articles/PMC4675844Test -
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المؤلفون: Bruno Kyewski, Sheena Pinto, Iris Martin, Chloé Michel, Rita Küchler
المصدر: Journal of immunological methods. 457
مصطلحات موضوعية: 0301 basic medicine, Immunology, Population, Cell Count, Thymus Gland, 03 medical and health sciences, Mice, In vivo, medicine, Immunology and Allergy, Animals, education, Lymph node, Cell Proliferation, education.field_of_study, DNA synthesis, Staining and Labeling, Chemistry, Cell growth, Cell Differentiation, Epithelial Cells, Flow Cytometry, Deoxyuridine, Small intestine, Epithelium, Cell biology, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, Administration, Intravenous, Ex vivo
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::634e4971f547692a8c9a8b9769d7dceeTest
https://pubmed.ncbi.nlm.nih.gov/29605230Test -
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المؤلفون: Meinrad Busslinger, Esther Lutgens, Norbert Gerdes, Tomoyoshi Yamano, Jelena Nedjic, Benedikt Brors, Madlen Steinert, Maria Hinterberger, Sheena Pinto, Naozumi Ishimaru, Sandra D Koser, Bruno Kyewski, Ludger Klein
المساهمون: Medical Biochemistry, ACS - Amsterdam Cardiovascular Sciences, AII - Amsterdam institute for Infection and Immunity
المصدر: Immunity, 42(6), 1048-1061. Cell Press
مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Immunology, Context (language use), Thymus Gland, Biology, Autoantigens, Mice, Negative selection, Downregulation and upregulation, Animals, Humans, Immunology and Allergy, CD40 Antigens, Clonal Selection, Antigen-Mediated, Antigen-presenting cell, Cells, Cultured, Mice, Knockout, Antigen Presentation, B-Lymphocytes, Mice, Inbred BALB C, Repertoire, Histocompatibility Antigens Class II, Cell Differentiation, Central T-cell tolerance induction, Immunoglobulin Class Switching, Cell biology, Infectious Diseases, Central Tolerance, B7-1 Antigen, Central tolerance, CD80, Signal Transduction, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81a56a3afa14eff3431ef68e94209df0Test
https://doi.org/10.1016/j.immuni.2015.05.013Test -
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المؤلفون: Tim Holland-Letz, Bruno Kyewski, Fabian Brunk, Alla Slynko, Sheena Pinto, Chloé Michel, Annette Kopp-Schneider
المصدر: European journal of immunology. 47(7)
مصطلحات موضوعية: 0301 basic medicine, Stromal cell, TEC, Cellular differentiation, education, Immunology, Genes, MHC Class II, Gene Expression, chemical and pharmacologic phenomena, Thymus Gland, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Organ Culture Techniques, Immunology and Allergy, Animals, Cell Lineage, Progenitor cell, Cells, Cultured, MHC class II, Thymocytes, biology, hemic and immune systems, Epithelial cell adhesion molecule, Cell Differentiation, Epithelial Cells, Models, Theoretical, Epithelial Cell Adhesion Molecule, Embryonic stem cell, Cell biology, 030104 developmental biology, chemistry, biology.protein, B7-1 Antigen, Leukocyte Common Antigens, Stem cell, tissues, 030215 immunology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b44088e36672097a7582b0b9f3fb2c7Test
https://pubmed.ncbi.nlm.nih.gov/28439878Test -
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المؤلفون: Bruno Kyewski, Hans Jürgen Stark, Sheena Pinto, Stefanie Egle, Petra Boukamp, Katrin Schmidt
المصدر: The Journal of Immunology. 190:1085-1093
مصطلحات موضوعية: Fibroblast Growth Factor 7, Cell division, T-Lymphocytes, Immunology, Cell Culture Techniques, Thymus Gland, Mice, Organ Culture Techniques, Pregnancy, Animals, Humans, Immunology and Allergy, Cell Lineage, Cells, Cultured, Regulation of gene expression, Thymocytes, biology, Lymphopoiesis, RANK Ligand, FOXN1, Epithelial Cells, Forkhead Transcription Factors, Dermis, Fibroblasts, Coculture Techniques, In vitro, Cell biology, Mice, Inbred C57BL, Gene Expression Regulation, Microscopy, Fluorescence, Organ Specificity, RANKL, T cell differentiation, B7-1 Antigen, biology.protein, Female, Developmental biology, Cell Division, CD80, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e879e602ec8c9a28afc689f6b9bce7Test
https://doi.org/10.4049/jimmunol.1201843Test -
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المؤلفون: Stefanie Rösch, Bruno Kyewski, Klaus Hexel, Sheena Pinto, Jens Derbinski
المصدر: Proceedings of the National Academy of Sciences. 105:657-662
مصطلحات موضوعية: T cell, Locus (genetics), Thymus Gland, Autoimmune Diseases, Mice, Gene expression, medicine, Animals, Lactation, Gene, Mice, Knockout, Regulation of gene expression, Mice, Inbred C3H, Stochastic Processes, Multidisciplinary, biology, Caseins, Epithelial Cells, Biological Sciences, Milk Proteins, Autoimmune regulator, Molecular biology, medicine.anatomical_structure, Gene Expression Regulation, B7-1 Antigen, Lactalbumin, biology.protein, Female, Whey Acidic Protein, Central tolerance
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4054052ee86818f40e8a10740f41a8aaTest
https://doi.org/10.1073/pnas.0707486105Test -
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المؤلفون: Bruno Kyewski, Hans Jürgen Stark, Sheena Pinto, Iris Martin, Petra Boukamp
المصدر: Journal of Visualized Experiments.
مصطلحات موضوعية: Cell type, Stromal cell, General Chemical Engineering, Cellular differentiation, T cell, Gene Expression, Thymus Gland, Biology, General Biochemistry, Genetics and Molecular Biology, Mice, Pregnancy, medicine, Animals, Cell Proliferation, Thymocytes, General Immunology and Microbiology, Cell growth, General Neuroscience, RANK Ligand, FOXN1, Cell Differentiation, Epithelial Cells, Coculture Techniques, Cell biology, Mice, Inbred C57BL, medicine.anatomical_structure, Female, Stromal Cells, Developmental biology, CD80, Developmental Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c25ef5f3fb2c6b2795903677a7e6107Test
https://doi.org/10.3791/52614Test -
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المؤلفون: Bruno Kyewski, Sheena Pinto, Benedikt Brors, Nathalie Harder, Stefan Wild, Karl Rohr, Hannah Schmidt-Glenewinkel, Chloé Michel
المصدر: Proceedings of the National Academy of Sciences. 110
مصطلحات موضوعية: Genetics, Multidisciplinary, Cellular differentiation, Gene Expression, Cell Differentiation, Epithelial Cells, Context (language use), Thymus Gland, Biology, Antigenic Variation, Autoantigens, Tolerance induction, Self Tolerance, PNAS Plus, Multigene Family, Gene expression, Humans, Gene pool, Central tolerance, Gene, Overlapping gene
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec40596648438b30f98cf19e54737ea8Test
https://doi.org/10.1073/pnas.1308311110Test