دورية أكاديمية
Image-Guided Magnetic Thermoseed Navigation and Tumor Ablation Using a Magnetic Resonance Imaging System
| العنوان: | Image-Guided Magnetic Thermoseed Navigation and Tumor Ablation Using a Magnetic Resonance Imaging System |
|---|---|
| المؤلفون: | Baker, Rebecca R, Payne, Christopher, Yu, Yichao, Mohseni, Matin, Connell, John J, Lin, Fangyu, Harrison, Ian F, Southern, Paul, Rudrapatna, Umesh S, Stuckey, Daniel J, Kalber, Tammy L, Siow, Bernard, Thorne, Lewis, Punwani, Shonit, Jones, Derek K, Emberton, Mark, Pankhurst, Quentin A, Lythgoe, Mark F |
| المصدر: | Advanced Science , Article 2105333. (2022) (In press). |
| بيانات النشر: | WILEY |
| سنة النشر: | 2022 |
| المجموعة: | University College London: UCL Discovery |
| مصطلحات موضوعية: | magnetic resonance imaging, magnetic resonance imaging-compatible, magnetic resonance navigation, minimally invasive, thermoablation |
| الوصف: | Medical therapies achieve their control at expense to the patient in the form of a range of toxicities, which incur costs and diminish quality of life. Magnetic resonance navigation is an emergent technique that enables image-guided remote-control of magnetically labeled therapies and devices in the body, using a magnetic resonance imaging (MRI) system. Minimally INvasive IMage-guided Ablation (MINIMA), a novel, minimally invasive, MRI-guided ablation technique, which has the potential to avoid traditional toxicities, is presented. It comprises a thermoseed navigated to a target site using magnetic propulsion gradients generated by an MRI scanner, before inducing localized cell death using an MR-compatible thermoablative device. The authors demonstrate precise thermoseed imaging and navigation through brain tissue using an MRI system (0.3 mm), and they perform thermoablation in vitro and in vivo within subcutaneous tumors, with the focal ablation volume finely controlled by heating duration. MINIMA is a novel theranostic platform, combining imaging, navigation, and heating to deliver diagnosis and therapy in a single device. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | text |
| اللغة: | English |
| العلاقة: | https://discovery.ucl.ac.uk/id/eprint/10143474/1/Baker_Image-Guided%20Magnetic%20Thermoseed%20Navigation%20and%20Tumor%20Ablation%20Using%20a%20Magnetic%20Resonance%20Imaging%20System_AOP.pdfTest; https://discovery.ucl.ac.uk/id/eprint/10143474Test/ |
| الإتاحة: | https://discovery.ucl.ac.uk/id/eprint/10143474/1/Baker_Image-Guided%20Magnetic%20Thermoseed%20Navigation%20and%20Tumor%20Ablation%20Using%20a%20Magnetic%20Resonance%20Imaging%20System_AOP.pdfTest https://discovery.ucl.ac.uk/id/eprint/10143474Test/ |
| حقوق: | open |
| رقم الانضمام: | edsbas.3D919722 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |