المؤلفون: Inge Grundke-Iqbal, Malika Bennecib, Khalid Iqbal, Cheng-Xin Gong

المصدر: FEBS Letters. 490:15-22

مصطلحات موضوعية: Threonine, Time Factors, environment and public health, Biochemistry, Calcium calmodulin protein kinase II, Structural Biology, 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine, Phosphoprotein Phosphatases, Serine, Enzyme Inhibitors, Phosphorylation, Oxazoles, biology, Chemistry, Autophosphorylation, Up-Regulation, Female, Alzheimer disease, medicine.medical_specialty, Protein phosphatase-2A, Metabolically active brain slice, Blotting, Western, Phosphatase, Tau protein, Biophysics, Hyperphosphorylation, tau Proteins, Dephosphorylation, Prosencephalon, Ca2+/calmodulin-dependent protein kinase, Internal medicine, Okadaic Acid, Genetics, medicine, Animals, Rats, Wistar, Protein kinase A, Molecular Biology, Ionophores, Protein phosphatase-1, Protein phosphatase 1, Cell Biology, Rats, enzymes and coenzymes (carbohydrates), Endocrinology, Calcium-Calmodulin-Dependent Protein Kinases, biology.protein, Marine Toxins, Abnormally hyperphosphorylated tau, Calcium-Calmodulin-Dependent Protein Kinase Type 2

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9b436a744c1250acaf353e2d731e8b7Test
https://doi.org/10.1016/s0014-5793Test(01)02127-5

المؤلفون: Thanh T. Nguyen, Robert Grundy, Terence J. O'Brien, Tracy Chen, Niall M. Corcoran, Dennis Velakoulis, Christopher M. Hovens, Nigel C. Jones

المصدر: Neurobiology of Disease, Vol 45, Iss 3, Pp 897-901 (2012)

مصطلحات موضوعية: Male, Sodium selenate, Time Factors, Stimulation, Convulsants, Pharmacology, Selenic Acid, Antioxidants, Pathogenesis, Rats, Sprague-Dawley, Epilepsy, chemistry.chemical_compound, Neuroblastoma, Enzyme Inhibitors, Phosphorylation, Selenium Compounds, Amygdala, Seizure, Dose–response relationship, medicine.anatomical_structure, Neurology, Biochemistry, Proline, tau Proteins, Transfection, lcsh:RC321-571, Leucine, Seizures, Cell Line, Tumor, Okadaic Acid, medicine, Animals, Humans, Hyperphosphorylated tau, Rats, Wistar, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Analysis of Variance, Dose-Response Relationship, Drug, Epilepsy models, Okadaic acid, medicine.disease, Electric Stimulation, Rats, Disease Models, Animal, chemistry, Gene Expression Regulation, Mutation, Selenic acid, Pentylenetetrazole, Therapy

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c1c69d66f0bbddc7bf4e613b4d39c2dTest
https://pubmed.ncbi.nlm.nih.gov/22182692Test

المؤلفون: Jean Jacques Martin, K Koopman, Peter Paul De Deyn, Sebastiaan Engelborghs, Nathalie Le Bastard, Guy Nagels

المساهمون: Internal Medicine Specializations, Clinical sciences, Neurology, Faculty of Engineering, Neuroprotection & Neuromodulation

المصدر: Vrije Universiteit Brussel
Neurochemistry international
Neurochemistry International, 55(4), 214-218. PERGAMON-ELSEVIER SCIENCE LTD

مصطلحات موضوعية: Male, Threonine, Pathology, MILD COGNITIVE IMPAIRMENT, Plaque, Amyloid, CLINICAL-DIAGNOSIS, Degenerative disease, Cerebrospinal fluid, MARKERS, Catalytic Domain, Phosphorylation, Aged, 80 and over, biology, Research Support, Non-U.S. Gov't, Brain, Neurofibrillary Tangles, Alzheimer's disease, Chemistry, Female, Autopsy, Psychology, PHOSPHORYLATED-TAU, Frontotemporal dementia, medicine.medical_specialty, Tau protein, tau Proteins, Sensitivity and Specificity, cerebrospinal fluid, Central nervous system disease, Diagnosis, Differential, Cellular and Molecular Neuroscience, CEREBROSPINAL-FLUID, Alzheimer Disease, Predictive Value of Tests, mental disorders, Journal Article, medicine, Dementia, Humans, Amino Acid Sequence, Hyperphosphorylated tau, Aged, Amyloid beta-Peptides, Dementia with Lewy bodies, biomarkers, Cell Biology, PERFORMANCE, medicine.disease, Peptide Fragments, biology.protein, Human medicine, dementia

وصف الملف: pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c74873e938e64e5d76ef525cb50e63Test
https://biblio.vub.ac.be/vubir/improved-discrimination-of-autopsyconfirmed-alzheimers-disease-ad-from-nonad-dementias-using-csf-ptau181pTest(97c5e850-dd4f-4745-b9a9-ec353839e93e).html

المؤلفون: M. Kidd, D.C. Davies, M.A. Kurt, David R. Howlett, Karen Duff

المساهمون: Uludağ Üniversitesi/Tıp Fakültesi., Kurt, M. Ayberk, AAR-4341-2020

المصدر: Neurobiology of Disease, Vol 14, Iss 1, Pp 89-97 (2003)

مصطلحات موضوعية: Pathology, Mutant, Hippocampus, Paired helical filaments, Beta-amyloid, Gene, Amyloid beta-Protein Precursor, Mice, Amyloid precursor protein, Senile plaques, Transgenes, Phosphorylation, Aged, 80 and over, biology, Chemistry, Age Factors, Brain, Immunogold labelling, Alzheimer's disease, Middle Aged, Neurology, β-Amyloid, Alzheimer’s disease, Neurofibrillary tangles, Adult, medicine.medical_specialty, A-beta amyloidosis, Immunocytochemistry, Mice, Transgenic, tau Proteins, Neurosciences & neurology, Dystrophic neurites, Presenilin, lcsh:RC321-571, Accumulation, Alzheimer Disease, mental disorders, Electron microscopy, medicine, Presenilin-1, Animals, Humans, Hyperphosphorylated tau, Transgenic mouse brain, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Aged, Neurosciences, Membrane Proteins, Molecular biology, nervous system diseases, Cortex (botany), Missense mutations, Mutation, biology.protein, Familial alzheimers-disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a770a75c3c38bfafa75b2662a0a9c6bTest
https://pubmed.ncbi.nlm.nih.gov/13678670Test

المؤلفون: Roger M. Nitsch, Mario Merlini, Debora Wanner

المساهمون: University of Zurich, Merlini, Mario

المصدر: Acta Neuropathologica

مصطلحات موضوعية: Male, 0301 basic medicine, Pathology, Internal elastic lamina, Cerebral arteries, 2804 Cellular and Molecular Neuroscience, Hippocampus, Neutrophil elastase, 0302 clinical medicine, Perivascular space, Netherlands, Aged, 80 and over, biology, Brain, 11359 Institute for Regenerative Medicine (IREM), medicine.anatomical_structure, 2728 Neurology (clinical), Blood-Brain Barrier, 10076 Center for Integrative Human Physiology, Disease Progression, Female, Cerebral amyloid angiopathy, Collagen, Alzheimer's disease, medicine.medical_specialty, Clinical Neurology, Neuroimaging, tau Proteins, 610 Medicine & health, Blood–brain barrier, Cerebrovascular pathology, Pathology and Forensic Medicine, 03 medical and health sciences, Cellular and Molecular Neuroscience, Alzheimer Disease, mental disorders, medicine, Humans, Hyperphosphorylated tau, Aged, Retrospective Studies, Psychiatric Status Rating Scales, Analysis of Variance, Original Paper, business.industry, medicine.disease, Vascular smooth muscle, Actins, Elastin, 2734 Pathology and Forensic Medicine, Cerebral Amyloid Angiopathy, 030104 developmental biology, Microvessels, biology.protein, 570 Life sciences, Neurology (clinical), business, 030217 neurology & neurosurgery

وصف الملف: 10.1007_s00401-016-1560-2.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ab20e964ecf501f750e4613986a566Test

المؤلفون: Malika Bennecib, Inge Grundke-Iqbal, Khalid Iqbal, Cheng-Xin Gong

المصدر: FEBS Letters. (1):87-93

مصطلحات موضوعية: Glycogen synthase kinase-3, Protein phosphatase-2A, Phosphatase, Tau protein, Biophysics, Hyperphosphorylation, tau Proteins, Biochemistry, Dephosphorylation, chemistry.chemical_compound, Glycogen Synthase Kinase 3, Prosencephalon, Structural Biology, GSK-3, CDC2 Protein Kinase, Okadaic Acid, Genetics, Phosphoprotein Phosphatases, Animals, Protein Phosphatase 2, Enzyme Inhibitors, Phosphorylation, Rats, Wistar, Protein kinase A, Molecular Biology, Oxazoles, biology, Glycogen Synthase Kinases, Protein phosphatase 1, Cyclin-Dependent Kinase 5, Protein phosphatase-1, Cell Biology, Okadaic acid, Molecular biology, Cyclin-Dependent Kinases, Cyclin dependent protein kinase, Rats, chemistry, Calcium-Calmodulin-Dependent Protein Kinases, biology.protein, Female, Marine Toxins, Alzheimer disease, Abnormally hyperphosphorylated tau

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::834170c3ae4abdecdab1b245eaea7396Test

المؤلفون: Fiona Grüninger, Annica Rönnbäck, Antonio Piras, Caroline Graff, Ludovic Collin

المصدر: Acta Neuropathologica Communications

مصطلحات موضوعية: 0301 basic medicine, Male, Pathology, medicine.medical_specialty, Tau protein, Cathepsin D, Nerve Tissue Proteins, tau Proteins, Neuropathology, Biology, Pathology and Forensic Medicine, Progressive supranuclear palsy, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Alzheimer Disease, Lysosomal-Associated Membrane Protein 1, Sequestosome-1 Protein, medicine, Autophagy, Corticobasal degeneration, Humans, Hyperphosphorylated tau, Adaptor Proteins, Signal Transducing, Aged, Aged, 80 and over, Research, Neurodegeneration, Brain, Neurodegenerative Diseases, Middle Aged, medicine.disease, Tauopathy, 030104 developmental biology, Postmortem Changes, biology.protein, Female, Dementia, Neurology (clinical), Supranuclear Palsy, Progressive, Alzheimer's disease, Lysosomes, Microtubule-Associated Proteins, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a9c6360904ae24be19721f78fbd5682Test