نتائج البحث - "Rinath Jeselsohn"

1

A Distinct Chromatin State Drives Therapeutic Resistance in Invasive Lobular Breast Cancer

المصدر: Cancer Res

مصطلحات موضوعية: Carcinoma, Lobular, Tamoxifen, Cancer Research, Receptors, Estrogen, Oncology, Drug Resistance, Neoplasm, Carcinoma, Ductal, Breast, Humans, Breast Neoplasms, Female, Prognosis, Chromatin, Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0ba56c1184a5cedf045c241e017be95Test
https://doi.org/10.1158/0008-5472.can-21-3186Test

2

The oral selective oestrogen receptor degrader (SERD) AZD9496 is comparable to fulvestrant in antagonising ER and circumventing endocrine resistance

المؤلفون: Agostina Nardone, Rachel Schiff, Henry Brown, Meghana V. Trivedi, Martin Shea, Mark Pilling, Jamunarani Veeraraghavan, Chandandeep Nagi, Rinath Jeselsohn, Carmine De Angelis, Oona Delpuech, Maria Letizia Cataldo, Tamika Mitchell, C. Kent Osborne, Mothaffar F. Rimawi, Hazel M. Weir, Gary C. Chamness, Xiaoyong Fu, Susan G. Hilsenbeck

المساهمون: Pilling, Mark [0000-0002-7446-6597], Apollo - University of Cambridge Repository, Nardone, A., Weir, H., Delpuech, O., Brown, H., De Angelis, C., Cataldo, M. L., Fu, X., Shea, M. J., Mitchell, T., Veeraraghavan, J., Nagi, C., Pilling, M., Rimawi, M. F., Trivedi, M., Hilsenbeck, S. G., Chamness, G. C., Jeselsohn, R., Osborne, C. K., Schiff, R.

المصدر: British Journal of Cancer

مصطلحات موضوعية: Cancer Research, Indoles, Neoplasms, Hormone-Dependent, Breast Neoplasms, Article, 03 medical and health sciences, chemistry.chemical_compound, Mice, MCF-7 Cell, 0302 clinical medicine, Breast cancer, Cinnamate, In vivo, medicine, Animals, Humans, Receptor, skin and connective tissue diseases, Fulvestrant, Cancer, Cell Proliferation, Estradiol, Animal, Cell growth, Estrogens, medicine.disease, Estrogen, Metastatic breast cancer, 3. Good health, Tamoxifen, Oncology, chemistry, Receptors, Estrogen, Indole, Cell culture, Cinnamates, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Cancer research, MCF-7 Cells, Heterografts, Female, Growth inhibition, Heterograft, Breast Neoplasm, Human, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1307add3c66d5075ec69b579adb4aedTest
http://europepmc.org/articles/PMC6353941Test

3

Are We Ready to Use ESR1 Mutations in Clinical Practice

المؤلفون: Rinath Jeselsohn

المصدر: Breast Care. 12:309-313

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c30b1b324f668483a8057a0dace9f7dTest
https://doi.org/10.1159/000481428Test

4

The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells

المصدر: eLife, Vol 7 (2018)
eLife

مصطلحات موضوعية: 0301 basic medicine, Indoles, Pyridines, medicine.medical_treatment, Estrogen receptor, Ligands, Piperazines, Protein Structure, Secondary, acquired drug resistance, 0302 clinical medicine, selective estrogen receptor Degrader, Biology (General), skin and connective tissue diseases, Fulvestrant, Cancer Biology, General Neuroscience, General Medicine, 3. Good health, 030220 oncology & carcinogenesis, MCF-7 Cells, Medicine, Female, hormones, hormone substitutes, and hormone antagonists, medicine.drug, Protein Binding, Research Article, Human, estrogen receptor, Selective Estrogen Receptor Modulators, QH301-705.5, Science, Breast Neoplasms, Palbociclib, General Biochemistry, Genetics and Molecular Biology, Bazedoxifene, 03 medical and health sciences, Structure-Activity Relationship, Breast cancer, breast cancer, Protein Domains, medicine, Humans, General Immunology and Microbiology, hormone therapy, business.industry, Estrogen Receptor alpha, medicine.disease, Antiestrogen, Tamoxifen, 030104 developmental biology, Drug Resistance, Neoplasm, Raloxifene Hydrochloride, Mutation, Cancer research, Mutant Proteins, Hormone therapy, business, Estrogen receptor alpha, ESR1 Somatic Mutation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a690f4a60a1ddcc6a9caac9dd90769d1Test
https://elifesciences.org/articles/37161Test

5

Blockade of AP-1 Potentiates Endocrine Therapy and Overcomes Resistance

المساهمون: Malorni, Luca, Giuliano, Mario, Migliaccio, Ilenia, Wang, Tao, Creighton, Chad J., Lupien, Mathieu, Fu, Xiaoyong, Hilsenbeck, Susan G., Healy, Nuala, DE ANGELIS, Carmine, Mazumdar, Abhijit, Trivedi, Meghana V., Massarweh, Suleiman, Gutierrez, Carolina, DE PLACIDO, Sabino, Jeselsohn, Rinath, Brown, Myle, Brown, Powel H., Kent Osborne, C., Schiff, Rachel

المصدر: Molecular cancer research : MCR, vol 14, iss 5

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Drug Resistance, Estrogen receptor, Mice, 0302 clinical medicine, Receptors, 2.1 Biological and endogenous factors, Aetiology, Promoter Regions, Genetic, Receptor, Cancer, Estradiol, Kinase, Drug Synergism, Receptors, Estrogen, Oncology, Cistrome, 030220 oncology & carcinogenesis, MCF-7 Cells, Female, medicine.drug, Oncology and Carcinogenesis, Breast Neoplasms, Biology, Article, Promoter Regions, 03 medical and health sciences, Genetic, Breast Cancer, Genetics, medicine, Animals, Humans, Endocrine system, Oncology & Carcinogenesis, Molecular Biology, Transcription factor, Cell Proliferation, medicine.disease, Estrogen, Xenograft Model Antitumor Assays, Transcription Factor AP-1, Tamoxifen, 030104 developmental biology, Drug Resistance, Neoplasm, Cancer research, Neoplasm, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a23f0374fb0ecd4ea52cee1eb879b96Test
https://doi.org/10.1158/1541-7786.mcr-15-0423Test

6

Abstract PD2-04: FOXA1 induces a pro-metastatic secretome through ER-dependent and independent transcriptional reprogramming in endocrine-resistant breast cancer

المصدر: Cancer Research. 77:PD2-04

مصطلحات موضوعية: Doxycycline, Cancer Research, business.industry, Cancer, medicine.disease, Metastasis, CTGF, Breast cancer, Oncology, Cancer cell, Cancer research, Medicine, FOXA1, business, Tamoxifen, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::66a25bd73c84b5487359ff901f667944Test
https://doi.org/10.1158/1538-7445.sabcs16-pd2-04Test

7

Abstract GS2-01: High levels of interferon-response gene signatures are associated with de novo and acquired resistance to CDK4/6 inhibitors in ER+ breast cancer

المصدر: Cancer Research. 80:GS2-01

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::62707dc1c64c8977590881b9cb8aac63Test
https://doi.org/10.1158/1538-7445.sabcs19-gs2-01Test

8

Mixed Invasive Ductal and Lobular Carcinoma of the Breast: Prognosis and the Importance of Histologic Grade

المؤلفون: Eric P. Winer, Melissa E. Hughes, Jane E. Brock, O. Metzger-Filho, Ines Vaz‐Luis, Nan Lin, Rinath Jeselsohn, Arlindo R. Ferreira, Deborah A. Dillon, William T. Barry

المصدر: The oncologist. 24(7)

مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, medicine.drug_class, Lobular carcinoma, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Internal medicine, Breast Cancer, medicine, Humans, skin and connective tissue diseases, neoplasms, Retrospective Studies, Aromatase inhibitor, business.industry, Proportional hazards model, Hazard ratio, Carcinoma, Ductal, Breast, Retrospective cohort study, Middle Aged, medicine.disease, Prognosis, body regions, Survival Rate, Carcinoma, Lobular, 030104 developmental biology, 030220 oncology & carcinogenesis, Invasive lobular carcinoma, Female, Neoplasm Grading, business, Tamoxifen, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca7a96cf8fe878b619c08b3d934cad22Test
https://pubmed.ncbi.nlm.nih.gov/30518616Test

9

The SERM/SERD Bazedoxifene Disrupts ESR1 Helix 12 to Overcome Acquired Hormone Resistance in Breast Cancer Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c4276046cfebc02ce194074611ff881Test
https://doi.org/10.1101/306472Test

10

Tamoxifen resistance in breast cancer is regulated by the EZH2–ERa–GREB1 transcriptional axis

المساهمون: Wu, Y., Zhang, Z., Cenciarini, M. E., Proietti, C. J., Amasino, M., Hong, T., Yang, M., Liao, Y., Chiang, H. -C., Kaklamani, V. G., Jeselsohn, R., Vadlamudi, R. K., Huang, T. H. -M., Li, R., De Angelis, C., Fu, X., Elizalde, P. V., Schiff, R., Brown, M., Xu, K.

المصدر: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, endocrine system diseases, Transcription, Genetic, Carcinogenesis, Estrogen receptor, Apoptosis, medicine.disease_cause, Epigenesis, Genetic, Mice, Tumor Cells, Cultured, Promoter Regions, Genetic, Carcinogenesi, DNA methylation, EZH2, Estrogen Antagonists, Tamoxifen resistance, purl.org/becyt/ford/3.1 [https], Estrogen Antagonist, Prognosis, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, Oncology, Histone methyltransferase, purl.org/becyt/ford/3 [https], Female, Breast Neoplasm, medicine.drug, Human, Xenograft Model Antitumor Assay, Prognosi, Mice, Nude, Breast Neoplasms, Biology, Article, Follow-Up Studie, Neoplasm Protein, 03 medical and health sciences, medicine, Biomarkers, Tumor, Animals, Humans, Enhancer of Zeste Homolog 2 Protein, Cell Proliferation, Epigenetic therapy, Animal, Estrogen Receptor alpha, Apoptosi, DNA Methylation, Antiestrogen, Xenograft Model Antitumor Assays, GREB1, ERalpha signaling, Tamoxifen, 030104 developmental biology, Drug Resistance, Neoplasm, Cancer research, Estrogen receptor alpha, Follow-Up Studies

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47146dd77fc4cad92104de67b3b101afTest
http://hdl.handle.net/11588/774418Test

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