نتائج البحث - "Agostina Nardone"

1

A Distinct Chromatin State Drives Therapeutic Resistance in Invasive Lobular Breast Cancer

المصدر: Cancer Res

مصطلحات موضوعية: Carcinoma, Lobular, Tamoxifen, Cancer Research, Receptors, Estrogen, Oncology, Drug Resistance, Neoplasm, Carcinoma, Ductal, Breast, Humans, Breast Neoplasms, Female, Prognosis, Chromatin, Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0ba56c1184a5cedf045c241e017be95Test
https://doi.org/10.1158/0008-5472.can-21-3186Test

2

The oral selective oestrogen receptor degrader (SERD) AZD9496 is comparable to fulvestrant in antagonising ER and circumventing endocrine resistance

المؤلفون: Agostina Nardone, Rachel Schiff, Henry Brown, Meghana V. Trivedi, Martin Shea, Mark Pilling, Jamunarani Veeraraghavan, Chandandeep Nagi, Rinath Jeselsohn, Carmine De Angelis, Oona Delpuech, Maria Letizia Cataldo, Tamika Mitchell, C. Kent Osborne, Mothaffar F. Rimawi, Hazel M. Weir, Gary C. Chamness, Xiaoyong Fu, Susan G. Hilsenbeck

المساهمون: Pilling, Mark [0000-0002-7446-6597], Apollo - University of Cambridge Repository, Nardone, A., Weir, H., Delpuech, O., Brown, H., De Angelis, C., Cataldo, M. L., Fu, X., Shea, M. J., Mitchell, T., Veeraraghavan, J., Nagi, C., Pilling, M., Rimawi, M. F., Trivedi, M., Hilsenbeck, S. G., Chamness, G. C., Jeselsohn, R., Osborne, C. K., Schiff, R.

المصدر: British Journal of Cancer

مصطلحات موضوعية: Cancer Research, Indoles, Neoplasms, Hormone-Dependent, Breast Neoplasms, Article, 03 medical and health sciences, chemistry.chemical_compound, Mice, MCF-7 Cell, 0302 clinical medicine, Breast cancer, Cinnamate, In vivo, medicine, Animals, Humans, Receptor, skin and connective tissue diseases, Fulvestrant, Cancer, Cell Proliferation, Estradiol, Animal, Cell growth, Estrogens, medicine.disease, Estrogen, Metastatic breast cancer, 3. Good health, Tamoxifen, Oncology, chemistry, Receptors, Estrogen, Indole, Cell culture, Cinnamates, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Cancer research, MCF-7 Cells, Heterografts, Female, Growth inhibition, Heterograft, Breast Neoplasm, Human, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1307add3c66d5075ec69b579adb4aedTest
http://europepmc.org/articles/PMC6353941Test

3

Abstract GS2-01: High levels of interferon-response gene signatures are associated with de novo and acquired resistance to CDK4/6 inhibitors in ER+ breast cancer

المصدر: Cancer Research. 80:GS2-01

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::62707dc1c64c8977590881b9cb8aac63Test
https://doi.org/10.1158/1538-7445.sabcs19-gs2-01Test

4

An epigenomic approach to therapy for tamoxifen-resistant breast cancer

المؤلفون: Nicholas Mitsiades, Rainer B. Lanz, Cristian Coarfa, Chad J. Creighton, Zheng Zhang, Yongcheng Song, Xiaoyong Fu, Bert W. O'Malley, C. Kent Osborne, Qin Feng, Constantine S. Mitsiades, Bin He, Agostina Nardone, James E. Bradner, Martin Shea, Rachel Schiff, Lei Wang, Susan G. Hilsenbeck

المصدر: Cell Research

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40c16f2d3cdf58d637fb10ef1da2be07Test
https://doi.org/10.1038/cr.2014.71Test

5

FOXA1 overexpression mediates endocrine resistance by altering the ER transcriptome and IL-8 expression in ER-positive breast cancer

المساهمون: Fu, X., Jeselsohn, R., Pereira, R., Hollingsworth, E. F., Creighton, C. J., Li, F., Shea, M., Nardone, A., De Angelis, C., Heiser, L. M., Anur, P., Wang, N., Grasso, C. S., Spellman, P. T., Griffith, O. L., Tsimelzon, A., Gutierrez, C., Huang, S., Edwards, D. P., Trivedi, M. V., Rimawi, M. F., Lopez-Terrada, D., Hilsenbeck, S. G., Gray, J. W., Brown, M., Osborne, C. K., Schiff, R.

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 113(43)

مصطلحات موضوعية: 0301 basic medicine, Hepatocyte Nuclear Factor 3-alpha, Antineoplastic Agents, Hormonal, Prognosi, Estrogen receptor, Breast Neoplasms, Biology, Transcriptome, 03 medical and health sciences, Breast cancer, Cell Line, Tumor, medicine, Humans, RNA, Small Interfering, Gene knockdown, Multidisciplinary, Pioneer factor, Interleukin-8, Estrogen Receptor alpha, medicine.disease, Prognosis, Survival Analysis, Gene Expression Regulation, Neoplastic, Tamoxifen, 030104 developmental biology, PNAS Plus, Drug Resistance, Neoplasm, Transcriptional reprogramming, Cancer research, Female, Survival Analysi, FOXA1, Estrogen receptor alpha, Breast Neoplasm, Endocrine resistance, Human, medicine.drug, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed2387c3c513051ae7743e2ef46a0318Test
https://pubmed.ncbi.nlm.nih.gov/27791031Test

6

Abstract P5-09-20: Development of a novel selective estrogen receptor down-regulator which shows efficacy in pre-clinical models of endocrine resistance

المؤلفون: Zena Wilson, Jon Curwen, Ermira Pazolli, Michael Hulse, N Reavey, Graeme Walker, Rachel Schiff, A.A. Rabow, Mandy Lawson, Rob H. Bradbury, Steve Powell, Agostina Nardone, Rachel Rowlinson, Celina M. D'Cruz, C. De Savi, Rowena Callis, Hazel M. Weir

المصدر: Cancer Research. 73:P5-09

مصطلحات موضوعية: Cancer Research, Fulvestrant, biology, medicine.drug_class, business.industry, Cancer, Pharmacology, medicine.disease, Breast cancer, Oncology, Estrogen, medicine, biology.protein, Aromatase, business, Estrogen receptor alpha, Selective Estrogen Receptor Down Regulator, Tamoxifen, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::c923447479bae56bc973afe1a903e8b2Test
https://doi.org/10.1158/0008-5472.sabcs13-p5-09-20Test

7

Overcoming endocrine resistance due to reduced PTEN levels in estrogen receptor-positive breast cancer by co-targeting mammalian target of rapamycin, protein kinase B, or mitogen-activated protein kinase kinase

المساهمون: Fu, Xiaoyong, Creighton, Chad J., Biswal, Nrusingh C., Kumar, Vijetha, Shea, Martin, Herrera, Sabrina, Contreras, Alejandro, Gutierrez, Carolina, Wang, Tao, Nanda, Sarmistha, Giuliano, Mario, Morrison, Glady, Nardone, Agostina, Karlin, Kristen L., Westbrook, Thomas F., Heiser, Laura M., Anur, Pavana, Spellman, Paul, Guichard, Sylvie M., Smith, Paul D., Davies, Barry R., Klinowska, Teresa, Lee, Adrian V., Mills, Gordon B., Rimawi, Mothaffar F., Hilsenbeck, Susan G., Gray, Joe W., Joshi, Amit, Osborne, C. K., Schiff, Rachel

المصدر: Breast Cancer Research : BCR

مصطلحات موضوعية: Cancer Research, Gene Expression, Mitogen-activated protein kinase kinase, Mitogen-Activated Protein Kinase, Phosphatidylinositol 3-Kinases, MCF-7 Cell, Sirolimu, ASK1, Molecular Targeted Therapy, Fulvestrant, Medicine(all), TOR Serine-Threonine Kinase, biology, Estradiol, TOR Serine-Threonine Kinases, 3. Good health, Editorial, Oncology, Receptors, Estrogen, Doxycycline, Gene Knockdown Techniques, MCF-7 Cells, Female, Mitogen-Activated Protein Kinases, Breast Neoplasm, Research Article, Human, Signal Transduction, Xenograft Model Antitumor Assay, Neoplasms, Hormone-Dependent, Antineoplastic Agents, Hormonal, Protein Kinase Inhibitor, Mice, Nude, Breast Neoplasms, PTEN, Animals, Humans, c-Raf, Protein kinase B, Protein Kinase Inhibitors, PI3K/AKT/mTOR pathway, Sirolimus, Animal, Cyclin-dependent kinase 4, Akt/PKB signaling pathway, PTEN Phosphohydrolase, Xenograft Model Antitumor Assays, Tamoxifen, Drug Resistance, Neoplasm, Gene Knockdown Technique, biology.protein, Cancer research, Phosphatidylinositol 3-Kinase, Proto-Oncogene Proteins c-akt

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b8e05d376b25b5859d608cc00f5d0fTest
https://pubmed.ncbi.nlm.nih.gov/25888162Test

8

Abstract LB-166: PARP inhibition effects on endocrine therapy and resistance in estrogen receptor positive (ER+) breast cancer models

المؤلفون: Susan G. Hilsenbeck, Amit Goldstein, Rachel Schiff, Tamika Mithchell, Xiaowei Xu, Martin Shea, Agostina Nardone, Huizhong Hu, Carmine De Angelis, Xiaoyong Fu, Mark J. O'Connor, Mahitha Rajendran, Kent Osborne, Gershon Y. Locker

المصدر: Cancer Research. 75:LB-166

مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, business.industry, medicine.drug_class, Estrogen receptor, Cancer, medicine.disease, Olaparib, chemistry.chemical_compound, Prostate cancer, Endocrinology, Breast cancer, Oncology, chemistry, Tumor progression, Estrogen, Internal medicine, Cancer research, medicine, business, Tamoxifen, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::643c6a2a882902cceef8a66f81038cafTest
https://doi.org/10.1158/1538-7445.am2015-lb-166Test

9

Pathway-Centric Integrative Analysis Identifies RRM2 as a Prognostic Marker in Breast Cancer Associated with Poor Survival and Tamoxifen Resistance

المصدر: Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 5, Pp 390-402 (2014)
Neoplasia (New York, N.Y.)

مصطلحات موضوعية: Cancer Research, Antineoplastic Agents, Hormonal, Ribonucleoside Diphosphate Reductase, Breast Neoplasms, Kaplan-Meier Estimate, Biology, In Vitro Techniques, Bioinformatics, lcsh:RC254-282, Mass Spectrometry, Article, Basal (phylogenetics), Metabolomics, Breast cancer, Cell Line, Tumor, medicine, Metabolome, Biomarkers, Tumor, Image Processing, Computer-Assisted, Humans, skin and connective tissue diseases, Oligonucleotide Array Sequence Analysis, Tissue microarray, medicine.disease, Prognosis, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Immunohistochemistry, 3. Good health, Tamoxifen, Cell culture, Drug Resistance, Neoplasm, Tissue Array Analysis, Cancer research, Female, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10499f112b6f653b9a2c4894b20cbe97Test

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