دورية أكاديمية
The Effects of Human Immunodeficiency Virus Type 1 (HIV-1) Antigen-Expanded Specific T-Cell Therapy and Vorinostat on Persistent HIV-1 Infection in People With HIV on Antiretroviral Therapy.
| العنوان: | The Effects of Human Immunodeficiency Virus Type 1 (HIV-1) Antigen-Expanded Specific T-Cell Therapy and Vorinostat on Persistent HIV-1 Infection in People With HIV on Antiretroviral Therapy. |
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| المؤلفون: | Gay, Cynthia L, Hanley, Patrick J, Falcinelli, Shane D, Kuruc, JoAnn D, Pedersen, Susan M, Kirchherr, Jennifer, Raines, Samuel L M, Motta, Cecilia M, Lazarski, Chris, Chansky, Pamela, Tanna, Jay, Shibli, Abeer, Datar, Anushree, McCann, Chase D, Sili, Uluhan, Ke, Ruian, Eron, Joseph J, Archin, Nancie, Goonetilleke, Nilu, Bollard, Catherine M, Margolis, David M |
| المصدر: | J Infect Dis ; ISSN:1537-6613 ; Volume:229 ; Issue:3 |
| بيانات النشر: | Silverchair Information Systems |
| سنة النشر: | 2024 |
| المجموعة: | PubMed Central (PMC) |
| مصطلحات موضوعية: | HIV latency, T-cell therapy, latency reversal |
| الوصف: | The histone deacetylase inhibitor vorinostat (VOR) can reverse human immunodeficiency virus type 1 (HIV-1) latency in vivo and allow T cells to clear infected cells in vitro. HIV-specific T cells (HXTCs) can be expanded ex vivo and have been safely administered to people with HIV (PWH) on antiretroviral therapy. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | https://doi.org/10.1093/infdis/jiad423Test; https://pubmed.ncbi.nlm.nih.gov/38349333Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10938201Test/ |
| DOI: | 10.1093/infdis/jiad423 |
| الإتاحة: | https://doi.org/10.1093/infdis/jiad423Test https://pubmed.ncbi.nlm.nih.gov/38349333Test https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10938201Test/ |
| حقوق: | © The Author(s) 2024. Published by Oxford University Press on behalf of Infectious Diseases Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. |
| رقم الانضمام: | edsbas.420F0344 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1093/infdis/jiad423 |
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