المؤلفون: Sanne Patiwael, Christian U. Blank, Ton N. Schumacher, Antoni Ribas, John B. A. G. Haanen, Anastasia Gangaev, Daisy Philips, Dirk Schadendorf, Joost H. van den Berg, Maartje W. Rohaan, Bastian Schilling, Elisa A. Rozeman, Pia Kvistborg, Olga I. Isaeva

المصدر: Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 43

مصطلحات موضوعية: Male, Receptors, Antigen, T-Cell, alpha-beta, Programmed Cell Death 1 Receptor, Medizin, Epitopes, T-Lymphocyte, CD8-Positive T-Lymphocytes, Lymphocyte Activation, Epitope, Cohort Studies, Epitopes, melanoma-reactive CD8 T cells, Receptors, PD-1, 80 and over, Cytotoxic T cell, CTLA-4 Antigen, Hepatitis A Virus Cellular Receptor 2, Immune Checkpoint Inhibitors, Melanoma, Cancer, alpha-beta, Aged, 80 and over, Multidisciplinary, Middle Aged, Biological Sciences, medicine.anatomical_structure, 5.1 Pharmaceuticals, Antigen, Female, Development of treatments and therapeutic interventions, medicine.symptom, Melanoma-Specific Antigens, Adult, Receptors, CXCR5, T cell, In Vitro Techniques, Clinical Research, medicine, Humans, Aged, business.industry, Compartment (ship), T-Cell, medicine.disease, CXCR5, Blockade, Kinetics, T-Lymphocyte, Mechanism of action, CTLA-4, Cancer research, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::994323e563648a11d8ffa0127b701604Test
https://doi.org/10.1073/pnas.2102849118Test

المؤلفون: Ton N. Schumacher, Elisa A. Rozeman, Bastian Schilling, Maartje W. Rohaan, John B. A. G. Haanen, Pia Kvistborg, Antoni Ribas, Dirk Schadendorf, Sanne Patiwael, Joost H. van den Berg, Anastasia Gangaev, Daisy Philips, Christian U. Blank

مصطلحات موضوعية: business.industry, Melanoma, T cell, medicine.disease, Epitope, Peripheral, Blockade, medicine.anatomical_structure, Mechanism of action, CTLA-4, Cancer research, Medicine, Cytotoxic T cell, medicine.symptom, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::55f4778522d652e945a423a387342f2dTest
https://doi.org/10.1101/2020.12.15.422827Test

المؤلفون: Christian U. Blank, Elisa A. Rozeman, David W. Vredevoogd, Hugo M. Horlings, Stephanie A. Blankenstein, Marieke Brüggemann, Julia Boshuizen, Beaunelle de Bruijn, Juliana C.N. Kenski, Max F. Madu, Keith T. Flaherty, Alexander C.J. van Akkooi, Ji-Ying Song, Dennie T. Frederick, Mara Parren, Oscar Krijgsman, Daniel S. Peeper, Maarten A. Ligtenberg, Genevieve M. Boland

المساهمون: Plastic, Reconstructive and Hand Surgery

المصدر: Nature communications, 11(1):3946. Nature Publishing Group
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)

مصطلحات موضوعية: Male, 0301 basic medicine, Skin Neoplasms, medicine.medical_treatment, Programmed Cell Death 1 Receptor, General Physics and Astronomy, Cancer immunotherapy, 02 engineering and technology, Mice, Antineoplastic Agents, Immunological, Tumor Microenvironment, Cytotoxic T cell, RNA-Seq, lcsh:Science, Melanoma, education.field_of_study, Multidisciplinary, 021001 nanoscience & nanotechnology, Gene Expression Regulation, Neoplastic, Cancer therapeutic resistance, medicine.anatomical_structure, Female, 0210 nano-technology, Proto-Oncogene Proteins B-raf, Science, Tumour heterogeneity, T cell, Population, Nerve Tissue Proteins, Receptors, Nerve Growth Factor, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Immune system, Antigen, Cell Line, Tumor, medicine, Animals, Humans, education, neoplasms, Protein Kinase Inhibitors, Mitogen-Activated Protein Kinase Kinases, business.industry, Brain-Derived Neurotrophic Factor, General Chemistry, Immunotherapy, medicine.disease, Xenograft Model Antitumor Assays, HEK293 Cells, 030104 developmental biology, Drug Resistance, Neoplasm, Cancer research, lcsh:Q, Tumor Escape, business, T-Lymphocytes, Cytotoxic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169ac84a0fc19e200b0badf8c6a353cfTest
https://pure.amc.nl/en/publications/reversal-of-preexisting-ngfrdriven-tumor-and-immune-therapy-resistanceTest(dda4d8a2-a72f-4a5a-b05a-12bc7aa97702).html

المؤلفون: Guangchun Han, Deborah A. Ledesma, Wenbin Liu, Jeffrey E. Lee, Michael T. Tetzlaff, Christine N. Spencer, Michael A. Davies, Vancheswaran Gopalakrishnan, Oscar Krijgsman, Daniel S. Peeper, Reetakshi Arora, Christian U. Blank, James P. Allison, Catherine Sautès-Fridman, Roberta Zapassodi, Sangeetha M. Reddy, Alexander J. Lazar, Raghu Kalluri, Wolf H. Fridman, Hao Zhao, Lisa H. Butterfield, Keren Yizhak, Lauren E. Haydu, Elisa A. Rozeman, Jennifer A. Wargo, Pierre Olivier Gaudreau, Fernanda G. Kugeratski, Alexandre Reuben, Valerie S. LeBleu, Jianjun Gao, Rafet Basar, Beth A. Helmink, Emily Z. Keung, Hussein Abdul-Hassan Tawbi, Padmanee Sharma, Alex P. Cogdill, Linghua Wang, Disha Rao, Kevin M. McBride, Patrick Hwu, Ton N. Schumacher, Monika A. Zelazowska, Elizabeth M. Burton, Rodabe N. Amaria, Moshe Sade-Feldman, Florent Petitprez, Sapna Pradyuman Patel, Yuanxin Xi, Anthony Lucci, Nir Hacohen, Jorge Blando, Shaojun Zhang, Katayoun Rezvani, Rohit Thakur, Scott E. Woodman, SuFey Ong, Michael Bailey, Sarah Warren, Courtney W. Hudgens, Jeffrey E. Gershenwald

المساهمون: The University of Texas M.D. Anderson Cancer Center [Houston], Massachusetts General Hospital [Boston], School of Engineering [Edinburgh], University of Edinburgh, Memorial Sloane Kettering Cancer Center [New York], Netherlands Cancer Institute (NKI), Antoni van Leeuwenhoek Hospital, University of Pittsburgh (PITT), Pennsylvania Commonwealth System of Higher Education (PCSHE), Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Gestionnaire, Hal Sorbonne Université

المصدر: Nature
Nature, Nature Publishing Group, 2020, 577 (7791), pp.549-555. ⟨10.1038/s41586-019-1922-8⟩
Nature, vol 577, iss 7791

مصطلحات موضوعية: 0301 basic medicine, T-Lymphocytes, medicine.medical_treatment, [SDV]Life Sciences [q-bio], Mass Spectrometry, 0302 clinical medicine, Cancer immunotherapy, Immunologic, Receptors, RNA-Seq, Receptors, Immunologic, Neoplasm Metastasis, Melanoma, Cancer, B-Lymphocytes, Tumor, Multidisciplinary, Prognosis, 3. Good health, [SDV] Life Sciences [q-bio], Gene Expression Regulation, Neoplastic, Phenotype, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Immunotherapy, Single-Cell Analysis, Stromal cell, General Science & Technology, T cell, [SDV.CAN]Life Sciences [q-bio]/Cancer, Biology, Article, Vaccine Related, 03 medical and health sciences, Immune system, [SDV.CAN] Life Sciences [q-bio]/Cancer, Biomarkers, Tumor, Genetics, medicine, Humans, Carcinoma, Renal Cell, B cell, Neoplastic, Carcinoma, Follicular, Renal Cell, Dendritic Cells, Cell Cycle Checkpoints, medicine.disease, Immune checkpoint, Clone Cells, Tertiary Lymphoid Structures, 030104 developmental biology, Gene Expression Regulation, Cancer research, Immunization, Transcriptome, Immunologic Memory, Dendritic Cells, Follicular, Biomarkers

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be208e7a5506de19270310bdcd5f46c7Test
https://hal.sorbonne-universite.fr/hal-02456277Test

المؤلفون: Christian U. Blank, Elisa A. Rozeman, Ines Pires da Silva, Esmée P. Hoefsmit, Kaspar Bresser, Annegien Broeks, Ton N. Schumacher, Ellen Kapiteijn, Richard A. Scolyer, Trieu-My Van, Jason Reeves, Oscar Krijgsman, Daniel S. Peeper, Steven L. C. Ketelaars, Jordan Conway, Ron M. Kerkhoven, Jacqueline E. van der Wal, Georgina V. Long, Sarah Warren, Petros Dimitriadis, Pia Kvistborg

المصدر: Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, 8(2). BMJ PUBLISHING GROUP
Journal for ImmunoTherapy of Cancer

مصطلحات موضوعية: Male, Uveal Neoplasms, 0301 basic medicine, Cancer Research, Skin Neoplasms, T cell, medicine.medical_treatment, Immunology, 03 medical and health sciences, 0302 clinical medicine, Antigen, melanoma, tumor microenvironment, Humans, Immunology and Allergy, Medicine, RC254-282, Retrospective Studies, Clinical/Translational Cancer Immunotherapy, Pharmacology, Tumor microenvironment, business.industry, Melanoma, Liver Neoplasms, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Immunotherapy, medicine.disease, immunity, Immune checkpoint, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, translational medical research, Cutaneous melanoma, Cancer research, Molecular Medicine, Immunohistochemistry, Female, immunotherapy, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::104977900a329903a1fe0ba46dec9971Test
https://doi.org/10.1136/jitc-2020-001501Test

المؤلفون: Arlene H. Sharpe, Andrea Schietinger, Anjana Rao, Dietmar Zehn, Axel Kallies, Christian U. Blank, E. John Wherry, Werner Held, Rachel C. Lynn, Patrick G. Hogan, Pamela L. Schwartzberg, Ton N. Schumacher, Mary Philip, Enrico Lugli, Daniel E. Speiser, Benjamin Youngblood, Nicholas P. Restifo, W. Nicholas Haining

المصدر: Nat Rev Immunol
Nature reviews. Immunology, vol. 19, no. 11, pp. 665-674
Nature Reviews Immunology

مصطلحات موضوعية: 0301 basic medicine, History, T cell, medicine.medical_treatment, T-Lymphocytes, Population, Programmed Cell Death 1 Receptor, Biology, medicine.disease_cause, Infections, Article, Education, Autoimmunity, 03 medical and health sciences, 0302 clinical medicine, Neoplasms, medicine, Animals, Humans, Epigenetics, Hepatocyte Nuclear Factor 1-alpha, education, education.field_of_study, Effector, High Mobility Group Proteins, Immunotherapy, 3. Good health, Computer Science Applications, Chronic infection, 030104 developmental biology, medicine.anatomical_structure, Immunology, Memory T cell, 030215 immunology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369ccb4fe5a58ae1653c78fa64943e41Test
https://pubmed.ncbi.nlm.nih.gov/31570879Test

المؤلفون: Wolfgang Mueller-Klieser, Evelyn Ullrich, E. K. Geissler, Andreas Villunger, Almut Brand, Sigrid Karrer, Kathrin Renner, André Steven, Peter J. Oefner, Stefan Walenta, Elisabeth Kohl, Annette Thiel, Christian U. Blank, Gudrun E. Koehl, Jacques Pouysségur, Sebastian Haferkamp, Maximilian Schmid, Marina Kreutz, Carina Matos, Stefan Fichtner-Feigl, Katja Dettmer, Petra Hoffmann, Ulrike Schleicher, Sebastian Klobuch, Barbara Seliger, Katrin Singer, Michael Kastenberger, Christian Bogdan, Matthias Mack, Mark Berneburg, K. Peter, Stephan Schreml, Uwe Ritter, Wolfgang Herr, Marlene Kolitzus, Andreas Mackensen, Christina Bruss, Rebecca Kesselring, Gabriele Schoenhammer

المصدر: Cell Metabolism. 24:657-671

مصطلحات موضوعية: Male, 0301 basic medicine, Cell Survival, Physiology, T-Lymphocytes, T cell, Apoptosis, Cell Count, CD8-Positive T-Lymphocytes, Biology, Sodium Lactate, Interferon-gamma, 03 medical and health sciences, chemistry.chemical_compound, Interleukin 21, Downregulation and upregulation, Cell Line, Tumor, medicine, Animals, Humans, Lactic Acid, Immunologic Surveillance, Melanoma, Molecular Biology, Cell Proliferation, L-Lactate Dehydrogenase, NFATC Transcription Factors, NFAT, Cell Biology, medicine.disease, Up-Regulation, Lactic acid, Isoenzymes, Killer Cells, Natural, Mice, Inbred C57BL, Phenotype, 030104 developmental biology, medicine.anatomical_structure, chemistry, Cell culture, Immunology, Cancer research, Interleukin 12, Cytokines, Lactate Dehydrogenase 5, Glycolysis, Infiltration (medical)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf27413e12a732bc06c9d03eab4c8d3dTest
https://doi.org/10.1016/j.cmet.2016.08.011Test

المؤلفون: Christian U. Blank, Akhiad Bercovich, Aviezer Lifshitz, Ido Yofe, Hugo M. Horlings, John B. A. G. Haanen, Hanjie Li, Ton N. Schumacher, Alexander C.J. van Akkooi, Anne van der Leun, Elisa A. Rozeman, Eyal David, Yael Baran, Dikla Gelbard-Solodkin, Marlous van den Braber, Amos Tanay, Ido Amit, Yaniv Lubling

المصدر: Cell

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, medicine.medical_treatment, T cell, Programmed Cell Death 1 Receptor, Cell, Population, CD8-Positive T-Lymphocytes, Biology, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Lymphocytes, Tumor-Infiltrating, Immune system, 0302 clinical medicine, Tumor Microenvironment, medicine, Humans, Cytotoxic T cell, education, Melanoma, 030304 developmental biology, Tumor microenvironment, education.field_of_study, 0303 health sciences, T-cell receptor, Immunotherapy, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Cancer research, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1583fa0c8771edd3830192ca7506e17Test
https://europepmc.org/articles/PMC7253294Test/

المؤلفون: Kathrin Renner, Christian U. Blank, Elisa A. Rozeman, Ruben Lacroix, Marina Kreutz

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, T-Lymphocytes, medicine.medical_treatment, T cell, Immunology, 03 medical and health sciences, 0302 clinical medicine, Cancer immunotherapy, Checkpoint blockade, Neoplasms, Tumor Microenvironment, medicine, Animals, Humans, Immunology and Allergy, Cytotoxic T cell, Cancer, Tumor microenvironment, Bladder cancer, L-Lactate Dehydrogenase, business.industry, Melanoma, Acidity, Lactic acid, Immunotherapy, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, Metabolism, Oncology, Immune therapy, 030220 oncology & carcinogenesis, Cancer research, business, Glycolysis

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b3d6c1a78099559165e243e985201cbTest
https://hdl.handle.net/1887/3627642Test

المؤلفون: Christian U. Blank, Roberto Caporali, Leonard H. Calabrese, Allan D. Kirk

المصدر: Journal of Autoimmunity. 115:102546

مصطلحات موضوعية: Graft Rejection, 0301 basic medicine, T-Lymphocytes, T cell, Immunology, medicine.disease_cause, Autoimmune Diseases, Autoimmunity, 03 medical and health sciences, 0302 clinical medicine, Immune system, Immunity, Neoplasms, medicine, Animals, Humans, Immunology and Allergy, Immune Checkpoint Inhibitors, 030203 arthritis & rheumatology, Autoimmune disease, business.industry, Cancer, Immune Checkpoint Proteins, medicine.disease, Transplant rejection, Transplantation, Disease Models, Animal, Self Tolerance, 030104 developmental biology, medicine.anatomical_structure, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dc0e337d9b19689fc8e6a1232530980Test
https://doi.org/10.1016/j.jaut.2020.102546Test