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المؤلفون: Yanli Wang, Xiaowan Huang, Xiao Zhang, Jingchen Wang, Keyan Li, Guotao Liu, Kexin Lu, Xiang Zhang, Chengping Xie, Teresa Zheng, Yung-Yi Cheng, Qiang Wang
المصدر: Molecules; Volume 27; Issue 15; Pages: 4738
مصطلحات موضوعية: Molecular Structure, Organic Chemistry, pentacyclic triterpene, allobetulin, conjugates, antitumor activity, apoptosis, nucleosides, Pharmaceutical Science, Antineoplastic Agents, Apoptosis, Nucleosides, Analytical Chemistry, Oxaliplatin, Structure-Activity Relationship, Chemistry (miscellaneous), Cell Line, Tumor, Drug Discovery, Molecular Medicine, Humans, Physical and Theoretical Chemistry, Cisplatin, Drug Screening Assays, Antitumor, Cell Proliferation
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab668889173c7650c98e9dc4545cb72fTest
https://pubmed.ncbi.nlm.nih.gov/35897914Test -
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المؤلفون: Susan L. Morris-Natschke, Kuo Hsiung Lee, Yung Yi Cheng, Hong Yin, Xue-Feng Huang, Ren-Feng An, Jing Zhou, Min-Jie Zhang, Wei Liu
المصدر: Journal of Natural Products. 84:616-629
مصطلحات موضوعية: Pharmaceutical Science, Antineoplastic Agents, Apoptosis, Diosgenin, Glutaric acid, 01 natural sciences, Analytical Chemistry, Structure-Activity Relationship, chemistry.chemical_compound, Cell Line, Tumor, Drug Discovery, medicine, Humans, Cytotoxic T cell, MTT assay, Cytotoxicity, Pharmacology, Molecular Structure, 010405 organic chemistry, Organic Chemistry, Cell Cycle Checkpoints, In vitro, 0104 chemical sciences, Molecular Docking Simulation, 010404 medicinal & biomolecular chemistry, Complementary and alternative medicine, chemistry, Biochemistry, Mechanism of action, Drug Design, Molecular Medicine, Drug Screening Assays, Antitumor, medicine.symptom, Lead compound
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e36bf14a8c68c0e0124e883af83df5Test
https://doi.org/10.1021/acs.jnatprod.0c00698Test -
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المؤلفون: Min-Tsang Hsieh, Yoshihisa Asada, Kuo Hsiung Lee, Wei Li, Qingbo Liu, Chin Ho Chen, Susan L. Morris-Natschke, Yung Yi Cheng, Kazuo Koike, Li Huang
المصدر: J Med Chem
مصطلحات موضوعية: Anti-HIV Agents, Human immunodeficiency virus (HIV), Pharmacology, medicine.disease_cause, Plant Roots, 01 natural sciences, Article, Rats, Sprague-Dawley, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Latency (engineering), 030304 developmental biology, 0303 health sciences, Plant roots, Plant Extracts, Gnidimacrin, Rats, Virus Latency, 0104 chemical sciences, Sprague dawley, 010404 medicinal & biomolecular chemistry, chemistry, HIV-1, Molecular Medicine, Diterpenes, Reactive Oxygen Species, Lead compound, DNA
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33ba19c905bb32372a0e043050d5a7f6Test
https://doi.org/10.1021/acs.jmedchem.9b00339Test -
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المؤلفون: Xiao-Lei, Huang, Jing-Lei, Chen, Xian-Lun, Li, Lei, Zhao, Ya-Dong, Cui, Jiang-Yun, Liu, Susan L, Morris-Natschke, Goto, Masuo, Yung-Yi, Cheng, Kuo-Hsiung, Lee, Dao-Feng, Chen, Jian, Zhang
المصدر: Journal of Asian natural products research. 23(7)
مصطلحات موضوعية: Structure-Activity Relationship, Molecular Structure, Cell Line, Tumor, MCF-7 Cells, Humans, Antineoplastic Agents, Drug Screening Assays, Antitumor, Diterpenes, Kaurane, Cell Proliferation
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::0e91994c3f3cbdcc53052ebb6544d568Test
https://pubmed.ncbi.nlm.nih.gov/32441118Test -
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المؤلفون: Shi‐Shan Yu, Kuo Hsiung Lee, Meihua Yang, Haifeng Wu, Susan L. Morris-Natschke, Xudong Xu, Yung Yi Cheng
المصدر: Med Res Rev
مصطلحات موضوعية: Anti-HIV Agents, Human immunodeficiency virus (HIV), HIV Infections, Drug resistance, medicine.disease_cause, Bioinformatics, Article, 03 medical and health sciences, Structure-Activity Relationship, 0302 clinical medicine, Triterpenoid, Acquired immunodeficiency syndrome (AIDS), Drug Discovery, medicine, Humans, Viral suppression, 030304 developmental biology, Pharmacology, 0303 health sciences, Anti hiv, Drug discovery, business.industry, Plant Extracts, medicine.disease, Triterpenes, Infectious disease (medical specialty), 030220 oncology & carcinogenesis, Molecular Medicine, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69e0a2f38d671805d103600672d486a7Test
https://pubmed.ncbi.nlm.nih.gov/32666531Test -
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المؤلفون: Yung Yi Cheng, Qi-Run Li, Masuo Goto, Kuo‐Hsiung Lee, Susan L. Morris-Natschke, Daofeng Chen, Jian Zhang, Xiao-Lei Huang, Ya-Dong Cui, Xiao-Gang Jiang, Chin Ho Chen, Lei Zhao
المصدر: Bioorganic & Medicinal Chemistry Letters. 50:128319
مصطلحات موضوعية: Anti-HIV Agents, Cell Survival, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Potential candidate, Antineoplastic Agents, Virus Replication, Biochemistry, Phorbol ester, Structure-Activity Relationship, Cell Line, Tumor, Phorbol Esters, Drug Discovery, Side chain, Humans, Potency, Cytotoxicity, Molecular Biology, Molecular Structure, Anti hiv, Chemistry, Organic Chemistry, Cell culture, HIV-1, Molecular Medicine, Selectivity
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1190fae77a4bbab3844268d6a60a20a3Test
https://doi.org/10.1016/j.bmcl.2021.128319Test -
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المؤلفون: Kuo Hsiung Lee, Meng Tung Tsai, Chin Yu Liu, Sheng-Chu Kuo, Tian Shung Wu, Hui-Yi Lin, Li-Jiau Huang, Jai Sing Yang, Yung Yi Cheng
المصدر: Bioorganic & Medicinal Chemistry Letters. 23:5223-5227
مصطلحات موضوعية: Vincristine, Pyrrolidines, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Quinolones, Biochemistry, Article, Structure-Activity Relationship, chemistry.chemical_compound, Cell Line, Tumor, Drug Discovery, medicine, Humans, Molecular Biology, Cell Proliferation, Dose-Response Relationship, Drug, Molecular Structure, Organic Chemistry, Prodrug, Mechanism of action, chemistry, Design synthesis, Cell culture, Drug Design, Molecular Medicine, Non small cell, Drug Screening Assays, Antitumor, medicine.symptom, Lead compound, Human cancer, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f7e1be6ff56a82e103ba5f0e603ec49Test
https://doi.org/10.1016/j.bmcl.2013.06.083Test -
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المؤلفون: Chin Yu Liu, Xiaoming Yang, Li-Jiau Huang, Chien-Ting Chen, Mei Hua Hsu, Li Chen Chou, Yung Yi Cheng, Kuo Hsiung Lee, Tian Shung Wu, Sheng-Chu Kuo
المصدر: European Journal of Medicinal Chemistry. 46:6046-6056
مصطلحات موضوعية: Vinca, Stereochemistry, Antineoplastic Agents, Methylenedioxy, Structure-Activity Relationship, chemistry.chemical_compound, Cell Line, Tumor, Neoplasms, Organoselenium Compounds, Drug Discovery, Benzene Derivatives, medicine, Humans, Cell Proliferation, Pharmacology, biology, Organic Chemistry, General Medicine, biology.organism_classification, Combinatorial chemistry, In vitro, Paclitaxel, chemistry, Mechanism of action, Cell culture, Quinolines, Antimitotic Agent, Drug Screening Assays, Antitumor, medicine.symptom, Lead compound
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8ffc7008d373ad69a808e87c260254bTest
https://doi.org/10.1016/j.ejmech.2011.10.017Test -
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المؤلفون: Li-Jiau Huang, Mei Hua Hsu, Yen Fang Wen, Chin Yu Liu, Chih Chang Liao, Sheng-Chu Kuo, Ling-Chu Chang, Meng Tung Tsai, Li Chen Chou, Kuo Hsiung Lee, Chi Hung Huang, Tian Shung Wu, Yung Yi Cheng, Hui-Yi Lin, Yu Zhao
المصدر: European journal of medicinal chemistry. 90
مصطلحات موضوعية: Male, Models, Molecular, Cell cycle checkpoint, Mice, Nude, Antineoplastic Agents, Apoptosis, HL-60 Cells, Pharmacology, Article, Mice, Structure-Activity Relationship, Liver Neoplasms, Experimental, Cell Line, Tumor, Drug Discovery, medicine, Potency, Structure–activity relationship, Animals, Humans, Naphthyridines, Cytotoxicity, Cell Proliferation, Mice, Inbred BALB C, Dose-Response Relationship, Drug, Molecular Structure, Cell growth, Chemistry, Organic Chemistry, Cell Cycle, General Medicine, Cell cycle, Mechanism of action, Drug Design, medicine.symptom, Drug Screening Assays, Antitumor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e42eec34bba439a6bf7e792fc48cf2eTest
https://pubmed.ncbi.nlm.nih.gov/25528332Test -
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المؤلفون: Chin Yu Liu, Sheng-Chu Kuo, Li-Jiau Huang, Yung Yi Cheng, Kuo Hsiung Lee, Cheng Tung Lin, Chi Hung Huang
المصدر: Molecules
Volume 18
Issue 7
Pages 8028-8045
Molecules, Vol 18, Iss 7, Pp 8028-8045 (2013)مصطلحات موضوعية: Stereochemistry, Pharmaceutical Science, Antineoplastic Agents, Methylenedioxy, Article, Analytical Chemistry, Dephosphorylation, lcsh:QD241-441, chemistry.chemical_compound, Mice, Structure-Activity Relationship, lcsh:Organic chemistry, prodrugs, Neoplasms, Drug Discovery, Animals, Humans, antitumor activity, Physical and Theoretical Chemistry, Phosphorylation, Chemistry, Quinolinium Compounds, Organic Chemistry, Regioselectivity, Prodrug, Phosphate, Xenograft Model Antitumor Assays, dephosphorylation, Diphosphates, MCF-7, Solubility, Chemistry (miscellaneous), MCF-7 Cells, Molecular Medicine, Methanol
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74ba9edd6e8bf34823bdb620aba50d21Test